دورية أكاديمية
Incidence, Etiology, and Outcomes of Community-Acquired Pneumonia: A Population-Based Study
| العنوان: | Incidence, Etiology, and Outcomes of Community-Acquired Pneumonia: A Population-Based Study |
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| المؤلفون: | Bjarnason, Agnar, Westin, Johan, Lindh, Magnus, Andersson, Lars-Magnus, Kristinsson, Karl G, Löve, Arthur, Baldursson, Olafur, Gottfredsson, Magnus |
| المساهمون: | 1 Univ Iceland, Fac Med, Reykjavik, Iceland Show more 2 Sahlgrens Univ Hosp, Dept Infect Dis, Gothenburg, Sweden Show more 3 Univ Gothenburg, Dept Infect Dis Clin Virol, Gothenburg, Sweden Show more 4 Landspitali Univ Hosp, Dept Med, Reykjavik, Iceland Show more 5 Landspitali Univ Hosp, Dept Microbiol, Reykjavik, Iceland Show more 6 Landspitali Univ Hosp, Dept Virol, Reykjavik, Iceland |
| بيانات النشر: | Oxford University Press |
| سنة النشر: | 2018 |
| المجموعة: | Hirsla - Landspítali University Hospital research archive |
| مصطلحات موضوعية: | Lungnabólga, Faraldsfræði, BAC12, VEI12, PAD12, TMD12, Pneumonia, etiology, Incidence |
| الوصف: | To access publisher's full text version of this article, please click on the hyperlink in Additional Links field or click on the hyperlink at the top of the page marked Files ; BACKGROUND: The microbial etiology of community-acquired pneumonia (CAP) is often unclear in clinical practice, and previous studies have produced variable results. Population-based studies examining etiology and incidence are lacking. This study examined the incidence and etiology of CAP requiring hospitalization in a population-based cohort as well as risk factors and outcomes for specific etiologies. METHODS: Consecutive admissions due to CAP in Reykjavik, Iceland were studied. Etiologic testing was performed with cultures, urine-antigen detection, and polymerase chain reaction analysis of airway samples. Outcomes were length of stay, intensive care unit admission, assisted ventilation, and mortality. RESULTS: The inclusion rate was 95%. The incidence of CAP requiring hospitalization was 20.6 cases per 10000 adults/year. A potential pathogen was detected in 52% (164 of 310) of admissions and in 74% (43 of 58) with complete sample sets. Streptococcuspneumoniae was the most common pathogen (61 of 310, 20%; incidence: 4.1/10000). Viruses were identified in 15% (47 of 310; incidence: 3.1/10000), Mycoplasmapneumoniae were identified in 12% (36 of 310; incidence: 2.4/10000), and multiple pathogens were identified in 10% (30 of 310; incidence: 2.0/10000). Recent antimicrobial therapy was associated with increased detection of M pneumoniae (P < .001), whereas a lack of recent antimicrobial therapy was associated with increased detection of S pneumoniae (P = .02). Symptoms and outcomes were similar irrespective of microbial etiology. CONCLUSIONS: Pneumococci, M pneumoniae, and viruses are the most common pathogens associated with CAP requiring hospital admission, and they all have a similar incidence that increases with age. Symptoms do not correlate with specific agents, and outcomes are similar irrespective of pathogens identified. ... |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| تدمد: | 2328-8957 |
| العلاقة: | Incidence, Etiology, and Outcomes of Community-Acquired Pneumonia: A Population-Based Study 2018, 5 (2) Open Forum Infectious Diseases; http://hdl.handle.net/2336/620570Test; Open Forum Infectious Diseases |
| DOI: | 10.1093/ofid/ofy010 |
| الإتاحة: | https://doi.org/10.1093/ofid/ofy010Test http://hdl.handle.net/2336/620570Test |
| حقوق: | Archived with thanks to Open Forum Infectious Diseases ; Open Access - Opinn aðgangur |
| رقم الانضمام: | edsbas.6865ED72 |
| قاعدة البيانات: | BASE |
Full Text Finder | تدمد: | 23288957 |
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| DOI: | 10.1093/ofid/ofy010 |