Antimicrobial susceptibility of Neisseria gonorrhoeae isolates from patients attending a public referral center for sexually transmitted diseases in Belo Horizonte, State of Minas Gerais, Brazil
| العنوان: | Antimicrobial susceptibility of Neisseria gonorrhoeae isolates from patients attending a public referral center for sexually transmitted diseases in Belo Horizonte, State of Minas Gerais, Brazil |
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| المؤلفون: | Virgilio Vieira Neto, Viviane Cata Preta Souza, Maria Juliana Bastos Teixeira, Enio Roberto Pietra Pedroso, Ligia Maria Bedeschi Costa |
| المصدر: | Revista da Sociedade Brasileira de Medicina Tropical v.46 n.3 2013 Revista da Sociedade Brasileira de Medicina Tropical Sociedade Brasileira de Medicina Tropical (SBMT) instacron:SBMT Revista da Sociedade Brasileira de Medicina Tropical, Vol 46, Iss 3, Pp 304-309 (2013) Revista da Sociedade Brasileira de Medicina Tropical, Volume: 46, Issue: 3, Pages: 304-309, Published: JUN 2013 |
| سنة النشر: | 2013 |
| مصطلحات موضوعية: | Microbiology (medical), Adult, Male, Spectinomycin, lcsh:Arctic medicine. Tropical medicine, Adolescent, lcsh:RC955-962, Gonorrhea, Microbial Sensitivity Tests, medicine.disease_cause, Azithromycin, Antimicrobial susceptibility, Microbiology, Young Adult, Antibiotic resistance, medicine, Humans, Urethritis, business.industry, E-test, Middle Aged, medicine.disease, bacterial infections and mycoses, Neisseria gonorrhoeae, Anti-Bacterial Agents, Penicillin, Infectious Diseases, Cross-Sectional Studies, Phenotype, Parasitology, Disk diffusion, Female, business, Cefixime, medicine.drug |
| الوصف: | Introduction The aim of this study was to determine the antimicrobial susceptibility of Neisseria gonorrhoeae isolates obtained from patients attending a public referral center for sexually transmitted diseases and specialized care services (STD/SCS) in Belo Horizonte, Brazil. Methods Between March 2011 and February 2012, 201 specimens of Neisseria gonorrhoeae were consecutively obtained from men with symptoms of urethritis and women with symptons of cervicitis or were obtained during their initial consultation. The strains were tested using the disk diffusion method, and the minimum inhibitory concentrations of azithromycin, cefixime, ceftriaxone, ciprofloxacin, chloramphenicol, penicillin, tetracycline and spectinomycin were determined using the E-test. Results The specimens were 100% sensitive to cefixime, ceftriaxone and spectinomycin and exhibited resistances of 4.5% (9/201), 21.4% (43/201), 11.9% (24/201), 22.4% (45/201) and 32.3% (65/201) to azithromycin, ciprofloxacin, chloramphenicol, penicillin and tetracycline, respectively. Intermediate sensitivities of 17.9% (36/201), 4% (8/201), 16.9% (34/201), 71.1% (143/201) and 22.9% (46/201) were observed for azithromycin, ciprofloxacin, chloramphenicol, penicillin and tetracycline, respectively. The specimens had plasmid-mediated resistance to penicillin PPNG 14.5% (29/201) and tetracycline TRNG 11.5% (23/201). Conclusions The high percentage of detected resistance to penicillin, tetracycline, chloramphenicol and ciprofloxacin indicates that these antibiotics are not appropriate for gonorrhea treatment at the Health Clinic and possibly in Belo Horizonte. The resistance and intermediate sensitivity of these isolates indicates that caution is recommended in the use of azithromycin and emphasizes the need to establish mechanisms for the surveillance of antimicrobial resistance for the effective control of gonorrhea. |
| وصف الملف: | text/html |
| تدمد: | 1678-9849 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8e175dd48a2cc3442c1bf1200acdb0dTest https://pubmed.ncbi.nlm.nih.gov/23856869Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....d8e175dd48a2cc3442c1bf1200acdb0d |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 16789849 |
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