التفاصيل البيبلوغرافية
| العنوان: |
Development of a Modular Tissue Phantom for Evaluating Vascular Access Devices |
| المؤلفون: |
Emily N. Boice, David Berard, Jose M. Gonzalez, Sofia I. Hernandez Torres, Zechariah J. Knowlton, Guy Avital, Eric J. Snider |
| المصدر: |
Bioengineering; Volume 9; Issue 7; Pages: 319 |
| بيانات النشر: |
Multidisciplinary Digital Publishing Institute |
| سنة النشر: |
2022 |
| المجموعة: |
MDPI Open Access Publishing |
| مصطلحات موضوعية: |
model development, automation, tissue phantom, vascular access device, medical devices, porcine, human, femoral, hypovolemia, nerve fiber |
| جغرافية الموضوع: |
agris |
| الوصف: |
Central vascular access (CVA) may be critical for trauma care and stabilizing the casualty. However, it requires skilled personnel, often unavailable during remote medical situations and combat casualty care scenarios. Automated CVA medical devices have the potential to make life-saving therapeutics available in these resource-limited scenarios, but they must be properly designed. Unfortunately, currently available tissue phantoms are inadequate for this use, resulting in delayed product development. Here, we present a tissue phantom that is modular in design, allowing for adjustable flow rate, circulating fluid pressure, vessel diameter, and vessel positions. The phantom consists of a gelatin cast using a 3D-printed mold with inserts representing vessels and bone locations. These removable inserts allow for tubing insertion which can mimic normal and hypovolemic flow, as well as pressure and vessel diameters. Trauma to the vessel wall is assessed using quantification of leak rates from the tubing after removal from the model. Lastly, the phantom can be adjusted to swine or human anatomy, including modeling the entire neurovascular bundle. Overall, this model can better recreate severe hypovolemic trauma cases and subject variability than commercial CVA trainers and may potentially accelerate automated CVA device development. |
| نوع الوثيقة: |
text |
| وصف الملف: |
application/pdf |
| اللغة: |
English |
| العلاقة: |
Biomedical Engineering and Biomaterials; https://dx.doi.org/10.3390/bioengineering9070319Test |
| DOI: |
10.3390/bioengineering9070319 |
| الإتاحة: |
https://doi.org/10.3390/bioengineering9070319Test |
| حقوق: |
https://creativecommons.org/licenses/by/4.0Test/ |
| رقم الانضمام: |
edsbas.914DC729 |
| قاعدة البيانات: |
BASE |
