التفاصيل البيبلوغرافية
| العنوان: |
Blockade of the Interleukin-21/Interleukin-21 Receptor Pathway Ameliorates Disease in Animal Models of Rheumatoid Arthritis. |
| المؤلفون: |
Young, Deborah A., Hegen, Martin, Margery Ma, Hak Ling, Whitters, Matthew J., Albert, Leo M., Lowe, Leslie, Senices, Mayra, Wu, Paul W., Sibley, Barbara, Leathurby, Yelena, Brown, Tom P., Nickerson-Nutter, Cheryl, Keith Jr., James C., Collins, Mary |
| المصدر: |
Arthritis & Rheumatism; Apr2007, Vol. 56 Issue 4, p1152-1163, 12p, 1 Black and White Photograph, 2 Charts, 4 Graphs |
| مصطلحات موضوعية: |
INTERLEUKINS, RHEUMATOID arthritis, RHEUMATOLOGY, PATHOLOGY, CYTOKINES, AUTOANTIBODIES |
| مستخلص: |
This article discusses findings of a study, which examined the effects of blocking interleukin-21 (IL-21) in two rodent models of rheumatoid arthritis (RA) to determine whether IL-21 contributes to their pathologic processes. A member of the type I cytokine family, IL-21 is related closely to IL-2 and IL-15. T cells produce inflammatory cytokines and help T cell-dependent autoantibody responses. |
| قاعدة البيانات: |
Complementary Index |
Full Text Finder