التفاصيل البيبلوغرافية
| العنوان: |
The evaluation of efficacy of atmospheric pressure plasma in diabetic ulcers healing: A randomized clinical trial. |
| المؤلفون: |
Samsavar, Shirin, Mahmoudi, HamidReza, Shakouri, Reza, Khani, Mohammad Reza, Molavi, Behnam, Moosavi, Jamal, Daneshpazhooh, Maryam, Etesami, Ifa, Shokri, Babak |
| المصدر: |
Dermatologic Therapy; Nov2021, Vol. 34 Issue 6, p1-8, 8p |
| مصطلحات موضوعية: |
FOOT ulcers, CLINICAL trials, DIABETIC foot, ATMOSPHERIC pressure, HEALING, LOW temperature plasmas |
| مستخلص: |
The aim of this study is to evaluate the efficacy and safety of cold atmospheric plasma (CAP) as a novel therapy for diabetic foot ulcers. This was an investigator‐blinded, randomized controlled trial of 14 weeks (6 weeks of treatment and 8 weeks of follow‐up). Twenty patients with diabetic foot ulcers were divided into two groups: the control group receiving standard wound care and the plasma group, which received CAP twice a week for six consecutive weeks in addition to standard wound care. The ulcer size, amount of exudate, and wound grading were determined weekly. Cold plasma was produced by applying a high voltage (4.5 kV) and a high frequency (22 kHz) to helium gas. Exudate from wounds treated with CAP showed a significant reduction in the third week after complete treatment (p = 0.039). The wound grading of the ulcers improved by the sixth week (p = 0.019), and the sizes of ulcers significantly decreased in the plasma group at the end of the treatment period (p = 0.007). In this randomized clinical trial, CAP was an effective treatment option for diabetic foot ulcers in terms of wound surface reduction and antibacterial effects. [ABSTRACT FROM AUTHOR] |
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| قاعدة البيانات: |
Complementary Index |
