التفاصيل البيبلوغرافية
| العنوان: |
Clinical characteristics and prognosis of paroxysmal sympathetic hyperactivity in patients with severe nontraumatic brain injury. |
| المؤلفون: |
Miao, He1,2 (AUTHOR), Huang, Huijin1 (AUTHOR), Chen, Weibi1 (AUTHOR), Su, Ying-Ying1 (AUTHOR), Zhang, Yan1 (AUTHOR) zhangylq@sina.com |
| المصدر: |
Brain Injury. 2023, Vol. 37 Issue 2, p95-100. 6p. |
| مصطلحات موضوعية: |
*HYPERKINESIA, *NEUROLOGICAL disorders, *ANALGESICS, *CEREBRAL infarction, *POSTVACCINAL encephalitis, *GLASGOW Coma Scale, *RESEARCH funding, *ANTI-NMDA receptor encephalitis, *BRAIN injuries, *CEREBRAL anoxia, *MIDAZOLAM, *SYMPATHETIC nervous system, *LONGITUDINAL method, *CLONAZEPAM, *ASPARTIC acid, *CEREBRAL ischemia, *DIAZEPAM |
| مستخلص: |
This prospective study investigated and analyzed the clinical characteristics and prognosis of paroxysmal sympathetic hyperactivity (PSH) in patients with severe nontraumatic brain injury. Patients presenting with severe nontraumatic brain injury with PSH from July 2018 to June 2019 were enrolled. A PSH assessment measure ≥ 8 points was used as the criterion for PSH. Clinical data, indicators related to PSH, treatment effects and the prognosis were prospectively collected and analyzed. A total of 220 patients with severe nontraumatic brain injury were analyzed, and PSH occurred in 8 patients (3.6%). The primary neurological diseases included acute cerebral infarction, anti-N-methyl-D-aspartate receptor encephalitis, hypoxic encephalopathy and acute disseminated encephalitis. The Glasgow Coma Scale score was lower than 8 in the 8 patients with PSH. Seven of these eight patients had a Glasgow outcome scale (GOS) score of 3 or less than 3, and one patient had a GOS of 5 after 6 months. The medicines that effectively controlled PSH included dexmedetomidine, clonazepam, midazolam and diazepam. Although the incidence was lower for nontraumatic brain injury complicated with PSH than for traumatic brain injury, patients with PSH had a more severe disease state and poorer prognoses. Dexmedetomidine might effectively control PSH. [ABSTRACT FROM AUTHOR] |
| قاعدة البيانات: |
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