المؤلفون: Georg Jocher, Vincent Grass, Sarah K Tschirner, Lydia Riepler, Stephan Breimann, Tuğberk Kaya, Madlen Oelsner, M Sabri Hamad, Laura I Hofmann, Carl P Blobel, Carsten B Schmidt‐Weber, Ozgun Gokce, Constanze A Jakwerth, Jakob Trimpert, Janine Kimpel, Andreas Pichlmair, Stefan F Lichtenthaler

المصدر: EMBO Rep. 23:e54305 (2022)
EMBO reports 23(6), e54305 (2022). doi:10.15252/embr.202154305

مصطلحات موضوعية: EMBO23, EMBO24, EMBO31, Article, Articles, A549, apratastat, DPC-333, ectodomain shedding, syncytia formation, genetics [Amyloid Precursor Protein Secretases], ADAM17 Protein, 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit::616 Krankheiten, genetics [Spike Glycoprotein, Coronavirus], Biochemistry, Cell Fusion, DPC‐333, ADAM10 Protein, genetics [ADAM10 Protein], ddc:570, Genetics, Humans, Lung, Molecular Biology, SARS-CoV-2, Apratastat, Dpc-333, Ectodomain Shedding, Syncytia Formation, Membrane Proteins, COVID-19, Virus Internalization, ddc, genetics [Membrane Proteins], metabolism [Spike Glycoprotein, Coronavirus], Spike Glycoprotein, Coronavirus, Metalloproteases, Angiotensin-Converting Enzyme 2, Amyloid Precursor Protein Secretases, metabolism [Membrane Proteins]

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2fa416da9c2b0eb78067136b09f89a20Test
https://doi.org/10.15252/embr.202154305Test

المؤلفون: Schlosser, Pascal, Tin, Adrienne, Matias-Garcia, Pamela R., Thio, Chris H. L., Joehanes, Roby, Liu, Hongbo, Weihs, Antoine, Yu, Zhi, Hoppmann, Anselm, Grundner-Culemann, Franziska, Min, Josine L., Adeyemo, Adebowale A., Agyemang, Charles, Ärnlöv, Johan, Aziz, Nasir A., Baccarelli, Andrea, Bochud, Murielle, Brenner, Hermann, Breteler, Monique M. B., Carmeli, Cristian, Chaker, Layal, Chambers, John C., Cole, Shelley A., Coresh, Josef, Corre, Tanguy, Correa, Adolfo, Cox, Simon R., de Klein, Niek, Delgado, Graciela E., Domingo-Relloso, Arce, Eckardt, Kai-Uwe, Ekici, Arif B., Endlich, Karlhans, Evans, Kathryn L., Floyd, James S., Fornage, Myriam, Franke, Lude, Fraszczyk, Eliza, Gao, Xu, Gào, Xīn, Ghanbari, Mohsen, Ghasemi, Sahar, Gieger, Christian, Greenland, Philip, Grove, Megan L., Harris, Sarah E., Hemani, Gibran, Henneman, Peter, Herder, Christian, Horvath, Steve, Hou, Lifang, Hurme, Mikko A., Hwang, Shih-Jen, Jarvelin, Marjo-Riitta, Kardia, Sharon L. R., Kasela, Silva, Kleber, Marcus E., Koenig, Wolfgang, Kooner, Jaspal S., Kramer, Holly, Kronenberg, Florian, Kühnel, Brigitte, Lehtimäki, Terho, Lind, Lars, Liu, Dan, Liu, Yongmei, Lloyd-Jones, Donald M., Lohman, Kurt, Lorkowski, Stefan, Lu, Ake T., Marioni, Riccardo E., März, Winfried, McCartney, Daniel L., Meeks, Karlijn A. C., Milani, Lili, Mishra, Pashupati P., Nauck, Matthias, Navas-Acien, Ana, Nowak, Christoph, Peters, Annette, Prokisch, Holger, Psaty, Bruce M., Raitakari, Olli T., Ratliff, Scott M., Reiner, Alex P., Rosas, Sylvia E., Schöttker, Ben, Schwartz, Joel, Sedaghat, Sanaz, Smith, Jennifer A., Sotoodehnia, Nona, Stocker, Hannah R., Stringhini, Silvia, Sundström, Johan, Swenson, Brenton R., Tellez-Plaza, Maria, van Meurs, Joyce B. J., van Vliet-Ostaptchouk, Jana V., Venema, Andrea, Verweij, Niek, Walker, Rosie M., Wielscher, Matthias, Winkelmann, Juliane, Wolffenbuttel, Bruce H. R., Zhao, Wei, Zheng, Yinan, Esko, Tõnu, Metspalu, Andres, Mägi, Reedik, Nelis, Mari, Loh, Marie, Snieder, Harold, Levy, Daniel, Waldenberger, Melanie, Susztak, Katalin, Köttgen, Anna, Teumer, Alexander

المساهمون: Public and occupational health, APH - Personalized Medicine, APH - Global Health, Human Genetics, AGEM - Amsterdam Gastroenterology Endocrinology Metabolism, ARD - Amsterdam Reproduction and Development, ACS - Diabetes & metabolism, ACS - Atherosclerosis & ischemic syndromes, Stem Cell Aging Leukemia and Lymphoma (SALL), Groningen Institute for Gastro Intestinal Genetics and Immunology (3GI), Center for Liver, Digestive and Metabolic Diseases (CLDM), Life Course Epidemiology (LCE), Tampere University, BioMediTech, Department of Clinical Chemistry, Clinical Medicine, Estonian Biobank Research Team, Genetics of DNA Methylation Consortium, Milani, L., Clinical Genetics, Amsterdam Gastroenterology Endocrinology Metabolism, Amsterdam Reproduction & Development, Epidemiology, Internal Medicine, Lee Kong Chian School of Medicine (LKCMedicine)

المصدر: Nature communications, 12(1):7174. Nature Publishing Group
Nature Communications, 12:7174. Nature Publishing Group
Nature communications, vol. 12, no. 1, pp. 7174
Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
Repisalud
Instituto de Salud Carlos III (ISCIII)
Nature Communications
Nat. Commun. 12:7174 (2021)
Nature Communications, 12(1):7174. Nature Publishing Group
et al. 2021, ' Meta-analyses identify DNA methylation associated with kidney function and damage ', Nature Communications, vol. 12, 7174 (2021) . https://doi.org/10.1038/s41467-021-27234-3Test
Schlosser, P, Tin, A, Matias-garcia, P R, Thio, C H L, Joehanes, R, Liu, H, Weihs, A, Yu, Z, Hoppmann, A, Grundner-culemann, F, Min, J L, Adeyemo, A A, Agyemang, C, Ärnlöv, J, Aziz, N A, Baccarelli, A, Bochud, M, Brenner, H, Breteler, M M B, Carmeli, C, Chaker, L, Chambers, J C, Cole, S A, Coresh, J, Corre, T, Correa, A, Cox, S R, De Klein, N, Delgado, G E, Domingo-relloso, A, Eckardt, K, Ekici, A B, Endlich, K, Evans, K L, Floyd, J S, Fornage, M, Franke, L, Fraszczyk, E, Gao, X, Gào, X, Ghanbari, M, Ghasemi, S, Gieger, C, Greenland, P, Grove, M L, Harris, S E, Hemani, G, Henneman, P, Herder, C, Horvath, S, Hou, L, Hurme, M A, Hwang, S, Jarvelin, M, Kardia, S L R, Kasela, S, Kleber, M E, Koenig, W, Kooner, J S, Kramer, H, Kronenberg, F, Kühnel, B, Lehtimäki, T, Lind, L, Liu, D, Liu, Y, Lloyd-jones, D M, Lohman, K, Lorkowski, S, Lu, A T, Marioni, R E, März, W, Mccartney, D L, Meeks, K A C, Milani, L, Mishra, P P, Nauck, M, Navas-acien, A, Nowak, C, Peters, A, Prokisch, H, Psaty, B M, Raitakari, O T, Ratliff, S M, Reiner, A P, Rosas, S E, Schöttker, B, Schwartz, J, Sedaghat, S, Smith, J A, Sotoodehnia, N, Stocker, H R, Stringhini, S, Sundström, J, Swenson, B R, Tellez-plaza, M, Van Meurs, J B J, Van Vliet-ostaptchouk, J V, Venema, A, Verweij, N, Walker, R M, Wielscher, M, Winkelmann, J, Wolffenbuttel, B H R, Zhao, W, Zheng, Y, Milani, L, Loh, M, Snieder, H, Levy, D, Waldenberger, M, Susztak, K, Köttgen, A & Teumer, A 2021, ' Meta-analyses identify DNA methylation associated with kidney function and damage ', Nature Communications, vol. 12, no. 1, 7174 . https://doi.org/10.1038/s41467-021-27234-3Test
Nature Communications 12(1), 7174 (2021). doi:10.1038/s41467-021-27234-3

مصطلحات موضوعية: Male, Epidemiology, physiopathology [Renal Insufficiency, Chronic], General Physics and Astronomy, genetics [Renal Insufficiency, Chronic], Kidney, Kidney Function Tests, genetics [Interferon Regulatory Factors], Chronic kidney disease, Urologi och njurmedicin, metabolism [Transcription Factors], Cardiac and Cardiovascular Systems, Membrane Protein, DNA methylation, Kardiologi, Multidisciplinary, metabolism [LIM Domain Proteins], genetics [Transcription Factors], LIM Domain Proteins, Middle Aged, ddc, genetics [Membrane Proteins], Interferon Regulatory Factors, Female, ddc:500, Medical Genetics, Glomerular Filtration Rate, Adult, Science, Article, General Biochemistry, Genetics and Molecular Biology, SDG 3 - Good Health and Well-being, metabolism [Renal Insufficiency, Chronic], Humans, Urology and Nephrology, physiopathology [Kidney], Medicine [Science], Renal Insufficiency, Chronic, Interferon Regulatory Factor, Medicinsk genetik, Aged, metabolism [Interferon Regulatory Factors], urogenital system, metabolism [Kidney], Membrane Proteins, General Chemistry, Translational research, 1182 Biochemistry, cell and molecular biology, CpG Islands, 3111 Biomedicine, genetics [LIM Domain Proteins], metabolism [Membrane Proteins], Transcription Factors

وصف الملف: application/pdf; fulltext

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a666ac8780ee854739b2d4005651ff27Test
https://pure.amc.nl/en/publications/metaanalyses-identify-dna-methylation-associated-with-kidney-function-and-damageTest(0b3d0490-c103-42d9-a83e-999de439d3e1).html

المؤلفون: Galina Apostolova, Isabella Cera, Patrick Feurle, Andre Fischer, Georg Dechant, Derek W. Morris, Andreas Abentung, Aodán Laighneach, Nico Wahl, Simon Sprenger, Michael Bucher, Eduard Stefan, Laura Whitton, David Teis, Cornelia Ablinger

المصدر: The EMBO journal 40(3), e103701 (2021). doi:10.15252/embj.2019103701
The EMBO Journal

مصطلحات موضوعية: Scaffold protein, Male, Cell Plasticity, human cognitive ability, metabolism [Endosomal Sorting Complexes Required for Transport], metabolism [Hippocampus], chemistry [Nuclear Proteins], Hippocampus, Chromatin, Epigenetics, Genomics & Functional Genomics, neuronal activity, Mice, 0302 clinical medicine, Cognition, Gene expression, Premovement neuronal activity, Gene Regulatory Networks, genetics [Schizophrenia], metabolism [Transcription Factors], Membrane & Intracellular Transport, metabolism [Nuclear Envelope], Cells, Cultured, Neurons, 0303 health sciences, General Neuroscience, chemistry [Transcription Factors], genetics [Matrix Attachment Region Binding Proteins], Nuclear Proteins, genetics [Nuclear Proteins], Articles, nuclear envelope, genetics [Transcription Factors], metabolism [Intellectual Disability], Chromatin, genetics [Membrane Proteins], Schizophrenia, metabolism [Neurons], metabolism [Schizophrenia], metabolism [Nuclear Proteins], Vacuolar Proton-Translocating ATPases, Nuclear Envelope, Biology, Article, General Biochemistry, Genetics and Molecular Biology, metabolism [Vacuolar Proton-Translocating ATPases], chemistry [Matrix Attachment Region Binding Proteins], 03 medical and health sciences, SATB2, Intellectual Disability, ddc:570, medicine, Inner membrane, Animals, Humans, chemistry [Membrane Proteins], metabolism [Cell Nucleus], Molecular Biology, Gene, 030304 developmental biology, Cell Nucleus, Endosomal Sorting Complexes Required for Transport, General Immunology and Microbiology, Mechanism (biology), Membrane Proteins, Matrix Attachment Region Binding Proteins, medicine.disease, cytology [Hippocampus], metabolism [Matrix Attachment Region Binding Proteins], Mutation, cytology [Neurons], ATPases Associated with Diverse Cellular Activities, chromatin, genetics [Intellectual Disability], metabolism [ATPases Associated with Diverse Cellular Activities], Neuroscience, 030217 neurology & neurosurgery, metabolism [Membrane Proteins], Transcription Factors, HeLa Cells

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd6c12f384e7aa85602f7c65d2d82289Test
https://pub.dzne.de/record/155832Test

المؤلفون: Prelli Bozzo, Caterina, Nchioua, Rayhane, Volcic, Meta, Koepke, Lennart, Krüger, Jana, Schütz, Desiree, Heller, Sandra, Stürzel, Christina M., Kmiec, Dorota, Conzelmann, Carina, Müller, Janis, Zech, Fabian, Braun, Elisabeth, Groß, Rüdiger, Wettstein, Lukas, Weil, Tatjana, Weiß, Johanna, Diofano, Federica, Rodríguez Alfonso, Armando A., Wiese, Sebastian, Sauter, Daniel, Münch, Jan, Goffinet, Christine, Catanese, Alberto, Schön, Michael, Boeckers, Tobias M., Stenger, Steffen, Sato, Kei, Just, Steffen, Kleger, Alexander, Sparrer, Konstantin M. J., Kirchhoff, Frank

المصدر: Nature Communications 12(1), 4584 (2021). doi:10.1038/s41467-021-24817-y
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Nature Communications

مصطلحات موضوعية: IFITM3 protein, human, viruses, virology [COVID-19], drug effects [Virus Attachment], genetics [RNA, Small Interfering], metabolism [Angiotensin-Converting Enzyme 2], genetics [Spike Glycoprotein, Coronavirus], antagonists & inhibitors [Membrane Proteins], antagonists & inhibitors [RNA-Binding Proteins], DDC 570 / Life sciences, Virusinfektion, Angeborene Immunität, drug effects [SARS-CoV-2], metabolism [Antigens, Differentiation], genetics [RNA-Binding Proteins], RNA, Small Interfering, skin and connective tissue diseases, Innate immunity, genetics [Angiotensin-Converting Enzyme 2], RNA-Binding Proteins, genetics [SARS-CoV-2], spike protein, SARS-CoV-2, respiratory system, genetics [Membrane Proteins], Host-Pathogen Interactions, pharmacology [Antibodies, Neutralizing], Spike Glycoprotein, Coronavirus, pharmacology [Interferon-beta], ddc:500, Angiotensin-Converting Enzyme 2, Virus diseases, Interferon inducers, Immunology, Protein Binding, Cells, Interferon-Induktor, Science, Virus Attachment, ACE2 protein, human, Angeborene Immunit��t, metabolism [RNA-Binding Proteins], IFITM2 protein, human, Article, metabolism [SARS-CoV-2], antagonists & inhibitors [Angiotensin-Converting Enzyme 2], ddc:570, Humans, Protein Interaction Domains and Motifs, ddc:610, Amino Acid Sequence, metabolism [RNA, Small Interfering], Fusion, leu-13 antigen, Binding Sites, Sequence Homology, Amino Acid, SARS-CoV-2, fungi, genetics [Antigens, Differentiation], COVID-19, Membrane Proteins, Interferon-beta, Antibodies, Neutralizing, Antigens, Differentiation, Immunity, Innate, respiratory tract diseases, body regions, Gene Expression Regulation, Viral infection, drug effects [Host-Pathogen Interactions], metabolism [Spike Glycoprotein, Coronavirus], genetics [Host-Pathogen Interactions], DDC 610 / Medicine & health, Sequence Alignment, metabolism [Membrane Proteins]

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc49410437957521bf8a06e7e4be82f2Test
https://pub.dzne.de/record/162717Test

المؤلفون: María Inés Mateo, Stephanie Schwartz, María Jesús Martín-Bermejo, Balbino Alarcón, Michael T. Heneka, Guadalupe Pereyra, José P. López-Atalaya, Markus P. Kummer, Paola Bovolenta, Frederic Brosseron, Aldo Borroto, Pilar Esteve, Javier Rueda-Carrasco

المساهمون: Ministerio de Economía y Competitividad (España), Agencia Estatal de Investigación (España), Ministerio de Ciencia, Innovación y Universidades (España), European Commission, Fundación Ramón Areces

المصدر: EMBO reports 22(11), e51696 (2021). doi:10.15252/embr.202051696
Digital.CSIC. Repositorio Institucional del CSIC
instname
EMBO Reports

مصطلحات موضوعية: Immunology, Regulator, Inflammation, metabolism [Microglia], multiple sclerosis, Biochemistry, Article, Mice, Downregulation and upregulation, reactive astrocytes, ddc:570, Genetics, medicine, Animals, Molecular Biology of Disease, Molecular Biology, Neuroinflammation, metabolism [Inflammation], activated microglia, Microglia, business.industry, Multiple sclerosis, Intracellular Signaling Peptides and Proteins, Membrane Proteins, Articles, Alzheimer's disease, medicine.disease, HIF pathway, Crosstalk (biology), genetics [Membrane Proteins], medicine.anatomical_structure, Astrocytes, Neuroinflammatory Diseases, medicine.symptom, business, Neuroscience, Alzheimer’s disease, metabolism [Intracellular Signaling Peptides and Proteins], metabolism [Membrane Proteins], Astrocyte

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13cb2528f4b06c69f59b945a6c441d04Test

المؤلفون: Emma Ong-Pålsson, Jasenka Rudan Njavro, Yvette Wilson, Martina Pigoni, Andree Schmidt, Stephan A. Müller, Michael Meyer, Jana Hartmann, Marc Aurel Busche, Jenny M. Gunnersen, Kathryn M. Munro, Stefan F. Lichtenthaler

المصدر: Molecular neurobiology 59(2), 1183-1198 (2022). doi:10.1007/s12035-021-02660-y

مصطلحات موضوعية: Article, Seizure protein 6, DigiGait, Rotarod, Anxiety, Spatial learning and memory, Neuroscience (miscellaneous), Motor Activity, Mice, Cellular and Molecular Neuroscience, ddc:570, Aspartic Acid Endopeptidases, Animals, Humans, Maze Learning, Mice, Knockout, Membrane Proteins, metabolism [Aspartic Acid Endopeptidases], metabolism [Amyloid Precursor Protein Secretases], ddc, Mice, Inbred C57BL, genetics [Membrane Proteins], Neurology, Amyloid Precursor Protein Secretases, metabolism [Membrane Proteins]

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa386019a5cc6178d4c136884ad54dafTest
https://mediatum.ub.tum.de/1704966Test

المؤلفون: Carl P. Blobel, Stefan F. Lichtenthaler, Samantha G. Lessard, Tak W. Mak, Renpeng Fang, David R. McIlwain, Miguel Otero, Gisela Weskamp, Coline Haxaire

المصدر: International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 21, Iss 8732, p 8732 (2020)
Volume 21
Issue 22
International journal of molecular sciences 21(22), 8732-(2020). doi:10.3390/ijms21228732

مصطلحات موضوعية: 0301 basic medicine, cytology [Chondrocytes], Appendicular skeleton, iRhom1 protein, mouse, EGFR protein, mouse, a disintegrin and metalloprotease 17, Cre recombinase, Cell Communication, genetics [Carrier Proteins], genetics [Integrases], lcsh:Chemistry, Mice, 0302 clinical medicine, Osteogenesis, metabolism [Transforming Growth Factor alpha], Growth Plate, lcsh:QH301-705.5, Spectroscopy, Bone growth, Mice, Knockout, Metalloproteinase, ADAM17, biology, Col2a1 protein, mouse, growth & development [Growth Plate], genetics [Chondrogenesis], Cell Differentiation, General Medicine, musculoskeletal system, Computer Science Applications, Cell biology, ddc, ErbB Receptors, genetics [Membrane Proteins], genetics [Osteogenesis], medicine.anatomical_structure, endochondral ossification, 030220 oncology & carcinogenesis, ddc:540, embryonic structures, Chondrogenesis, metabolism [ErbB Receptors], Signal Transduction, animal structures, genetics [ADAM17 Protein], ADAM17 Protein, Catalysis, Adam17 protein, mouse, Article, iRhom1, 2, Inorganic Chemistry, genetics [ErbB Receptors], genetics [Transforming Growth Factor alpha], 03 medical and health sciences, metabolism [ADAM17 Protein], Calcification, Physiologic, Chondrocytes, metabolism [Integrases], iRhom2 protein, mouse, Disintegrin, medicine, Animals, Egfr signaling, Physical and Theoretical Chemistry, Molecular Biology, Endochondral ossification, deficiency [Membrane Proteins], Collagen Type II, genetics [Calcification, Physiologic], Cell Proliferation, Integrases, Organic Chemistry, metabolism [Collagen Type II], metabolism [Chondrocytes], metabolism [Growth Plate], Membrane Proteins, Transforming Growth Factor alpha, 030104 developmental biology, genetics [Collagen Type II], lcsh:Biology (General), lcsh:QD1-999, Gene Expression Regulation, Egfr mutation, biology.protein, Growth plates, inactive Rhomboid 1, 2, Carrier Proteins, metabolism [Membrane Proteins], metabolism [Carrier Proteins]

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a5dfc577f0ef5f1640706ce4216013dTest
https://pubmed.ncbi.nlm.nih.gov/33227998Test

المؤلفون: Martin H. Schludi, Markus Damme, Wolfgang Wurst, Matthias Brendel, Dieter Edbauer, Katrin Fellerer, Anja Capell, Benedikt Wefers, Johannes Gnörich, Georg Werner, Christian Haass, Karin Wind

المصدر: EMBO reports 21(10), 19 (2020). doi:10.15252/embr.202050241
EMBO Reports
EMBO Rep. 21:e50241 (2020)

مصطلحات موضوعية: Pathology, medicine.medical_specialty, TDP-43, Nerve Tissue Proteins, Biology, Biochemistry, Article, 03 medical and health sciences, Mice, genetics [Progranulins], 0302 clinical medicine, Progranulins, Downregulation and upregulation, Ftd, Neurodegeneration, Progranulin, Tdp-43, Tmem106b, ddc:570, Gene expression, mental disorders, Genetics, medicine, progranulin, Animals, Humans, Molecular Biology of Disease, Molecular Biology, Gene knockout, Loss function, 030304 developmental biology, Mice, Knockout, 0303 health sciences, genetics [Intercellular Signaling Peptides and Proteins], neurodegeneration, Membrane Proteins, FTD, Frontotemporal lobar degeneration, Articles, medicine.disease, TDP‐43, genetics [Membrane Proteins], Proteostasis, TMEM106B, Intercellular Signaling Peptides and Proteins, genetics [Frontotemporal Lobar Degeneration], Frontotemporal Lobar Degeneration, Haploinsufficiency, Lysosomes, 030217 neurology & neurosurgery, Neuroscience

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df22da9d1bf1034c18000cc5bb17bb30Test
https://pub.dzne.de/record/154374Test

المؤلفون: Franz Hagn, Kai Schlepckow, Bettina Brunner, Harald Steiner, Andrea Steiner, Christian Haass

المصدر: The EMBO journal 39(20), e104247 (2020). doi:10.15252/embj.2019104247
The EMBO Journal

مصطلحات موضوعية: Protein Conformation, alpha-Helical, chemistry [Membrane Glycoproteins], Magnetic Resonance Spectroscopy, genetics [Amyloid Precursor Protein Secretases], genetics [Alzheimer Disease], metabolism [Microglia], 0302 clinical medicine, genetics [Membrane Glycoproteins], Membrane region, Structural Biology, Risk Factors, genetics [Adaptor Proteins, Signal Transducing], TREM2, genetics [Receptors, Immunologic], Receptors, Immunologic, Receptor, chemistry.chemical_classification, 0303 health sciences, Membrane Glycoproteins, General Neuroscience, Circular Dichroism, metabolism [Receptors, Immunologic], Articles, dynamics, Amino acid, ddc, Molecular Docking Simulation, Transmembrane domain, genetics [Membrane Proteins], Ectodomain, chemistry [Receptors, Immunologic], Microglia, metabolism [Alzheimer Disease], Signal Transduction, Intramembrane protease, Biology, Molecular Dynamics Simulation, Cleavage (embryo), genetics [Signal Transduction], General Biochemistry, Genetics and Molecular Biology, Article, metabolism [Cell Membrane], 03 medical and health sciences, metabolism [Adaptor Proteins, Signal Transducing], Protein Domains, Alzheimer Disease, ddc:570, Humans, chemistry [Membrane Proteins], structure, Molecular Biology, 030304 developmental biology, Adaptor Proteins, Signal Transducing, General Immunology and Microbiology, Cell Membrane, enzymology [Alzheimer Disease], Membrane Proteins, Post-translational Modifications, Proteolysis & Proteomics, chemistry [Adaptor Proteins, Signal Transducing], NMR, metabolism [Amyloid Precursor Protein Secretases], HEK293 Cells, chemistry, Mutation, biology.protein, Biophysics, Amyloid Precursor Protein Secretases, metabolism [Membrane Glycoproteins], 030217 neurology & neurosurgery, metabolism [Membrane Proteins], intramembrane protease, Neuroscience

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::336001d0982d8a4fa0349c4e2f1ac011Test

المؤلفون: Björn Rabe, Torben Mentrup, Florencia Cabrera-Cabrera, Ann-Christine Gradtke, Akio Fukumori, Kosta Theodorou, Regina Fluhrer, Andreas Tholey, Marjo M. P. C. Donners, Kathrin Happ, Marion J.J. Gijbels, Andreas O. Helbig, Harald Steiner, Bernd Schröder

المساهمون: RS: CARIM - R3 - Vascular biology, Pathologie, Moleculaire Genetica, RS: Carim - B07 The vulnerable plaque: makers and markers, Medical Biochemistry, ACS - Atherosclerosis & ischemic syndromes, AII - Inflammatory diseases

المصدر: Journal of Experimental Medicine, 216(4), 807-830. Rockefeller University Press
Journal of experimental medicine 216(4), 807-830 (2019). doi:10.1084/jem.20171438
Journal of experimental medicine, 216(4), 807-830. Rockefeller University Press
The Journal of Experimental Medicine

مصطلحات موضوعية: 0301 basic medicine, medicine.medical_treatment, NF-KAPPA-B, TISSUE GROWTH-FACTOR, NUCLEAR TRANSLOCATION, 030204 cardiovascular system & hematology, PROTEASE SPPL2A, ADAM10 Protein, Mice, 0302 clinical medicine, metabolism [Scavenger Receptors, Class E], Aspartic Acid Endopeptidases, Immunology and Allergy, metabolism [Atherosclerosis], Receptor, Research Articles, OXIDIZED LDL RECEPTOR-1, Mice, Knockout, integumentary system, Kinase, Chemistry, Dipeptides, OX-LDL, antagonists & inhibitors [Aspartic Acid Endopeptidases], metabolism [Aspartic Acid Endopeptidases], Scavenger Receptors, Class E, Cell biology, Transmembrane domain, genetics [Membrane Proteins], Ectodomain, metabolism [ADAM10 Protein], lipids (amino acids, peptides, and proteins), pharmacology [Dipeptides], Signal peptide, Proteases, Immunology, LOW-DENSITY-LIPOPROTEIN, Transfection, PEPTIDASE-LIKE 2A, DENDRITIC CELLS, Article, 03 medical and health sciences, metabolism [Endothelial Cells], medicine, Animals, Humans, genetics [Scavenger Receptors, Class E], ddc:610, PROMOTES ATHEROSCLEROSIS, Growth factor, Endothelial Cells, Membrane Proteins, Atherosclerosis, metabolism [Amyloid Precursor Protein Secretases], CTGF, Mice, Inbred C57BL, 030104 developmental biology, HEK293 Cells, genetics [Aspartic Acid Endopeptidases], Proteolysis, Amyloid Precursor Protein Secretases, metabolism [Membrane Proteins], HeLa Cells

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ffa6a4d6e22e67e518e3fac901144feTest
https://cris.maastrichtuniversity.nl/en/publications/cee764c5-af8e-4b98-b7d7-845e25dbe728Test