المؤلفون: Daniel H. Katz, Usman A. Tahir, Alexander G. Bick, Akhil Pampana, Debby Ngo, Mark D. Benson, Zhi Yu, Jeremy M. Robbins, Zsu-Zsu Chen, Daniel E. Cruz, Shuliang Deng, Laurie Farrell, Sumita Sinha, Alec A. Schmaier, Dongxiao Shen, Yan Gao, Michael E. Hall, Adolfo Correa, Russell P. Tracy, Peter Durda, Kent D. Taylor, Yongmei Liu, W. Craig Johnson, Xiuqing Guo, Jie Yao, Yii-Der Ida Chen, Ani W. Manichaikul, Deepti Jain, Claude Bouchard, Mark A. Sarzynski, Stephen S. Rich, Jerome I. Rotter, Thomas J. Wang, James G. Wilson, Pradeep Natarajan, Robert E. Gerszten, Namiko Abe, Gonçalo Abecasis, Francois Aguet, Christine Albert, Laura Almasy, Alvaro Alonso, Seth Ament, Peter Anderson, Pramod Anugu, Deborah Applebaum-Bowden, Kristin Ardlie, Dan Arking, Donna K. Arnett, Allison Ashley-Koch, Stella Aslibekyan, Tim Assimes, Paul Auer, Dimitrios Avramopoulos, Najib Ayas, Adithya Balasubramanian, John Barnard, Kathleen Barnes, R. Graham Barr, Emily Barron-Casella, Lucas Barwick, Terri Beaty, Gerald Beck, Diane Becker, Lewis Becker, Rebecca Beer, Amber Beitelshees, Emelia Benjamin, Takis Benos, Marcos Bezerra, Larry Bielak, Joshua Bis, Thomas Blackwell, John Blangero, Eric Boerwinkle, Donald W. Bowden, Russell Bowler, Jennifer Brody, Ulrich Broeckel, Jai Broome, Deborah Brown, Karen Bunting, Esteban Burchard, Carlos Bustamante, Erin Buth, Brian Cade, Jonathan Cardwell, Vincent Carey, Julie Carrier, April Carson, Cara Carty, Richard Casaburi, Juan P. Casas Romero, James Casella, Peter Castaldi, Mark Chaffin, Christy Chang, Yi-Cheng Chang, Daniel Chasman, Sameer Chavan, Bo-Juen Chen, Wei-Min Chen, Michael Cho, Seung Hoan Choi, Lee-Ming Chuang, Mina Chung, Ren-Hua Chung, Clary Clish, Suzy Comhair, Matthew Conomos, Elaine Cornell, Carolyn Crandall, James Crapo, L. Adrienne Cupples, Joanne Curran, Jeffrey Curtis, Brian Custer, Coleen Damcott, Dawood Darbar, Sean David, Colleen Davis, Michelle Daya, Mariza de Andrade, Lisa de las Fuentes, Paul de Vries, Michael DeBaun, Ranjan Deka, Dawn DeMeo, Scott Devine, Huyen Dinh, Harsha Doddapaneni, Qing Duan, Shannon Dugan-Perez, Ravi Duggirala, Jon Peter Durda, Susan K. Dutcher, Charles Eaton, Lynette Ekunwe, Adel El Boueiz, Patrick Ellinor, Leslie Emery, Serpil Erzurum, Charles Farber, Jesse Farek, Tasha Fingerlin, Matthew Flickinger, Myriam Fornage, Nora Franceschini, Chris Frazar, Mao Fu, Stephanie M. Fullerton, Lucinda Fulton, Stacey Gabriel, Weiniu Gan, Shanshan Gao, Margery Gass, Heather Geiger, Bruce Gelb, Mark Geraci, Soren Germer, Robert Gerszten, Auyon Ghosh, Richard Gibbs, Chris Gignoux, Mark Gladwin, David Glahn, Stephanie Gogarten, Da-Wei Gong, Harald Goring, Sharon Graw, Kathryn J. Gray, Daniel Grine, Colin Gross, C. Charles Gu, Yue Guan, Namrata Gupta, David M. Haas, Jeff Haessler, Michael Hall, Yi Han, Patrick Hanly, Daniel Harris, Nicola L. Hawley, Jiang He, Ben Heavner, Susan Heckbert, Ryan Hernandez, David Herrington, Craig Hersh, Bertha Hidalgo, James Hixson, Brian Hobbs, John Hokanson, Elliott Hong, Karin Hoth, Chao (Agnes) Hsiung, Jianhong Hu, Yi-Jen Hung, Haley Huston, Chii Min Hwu, Marguerite Ryan Irvin, Rebecca Jackson, Cashell Jaquish, Jill Johnsen, Andrew Johnson, Craig Johnson, Rich Johnston, Kimberly Jones, Hyun Min Kang, Robert Kaplan, Sharon Kardia, Shannon Kelly, Eimear Kenny, Michael Kessler, Alyna Khan, Ziad Khan, Wonji Kim, John Kimoff, Greg Kinney, Barbara Konkle, Charles Kooperberg, Holly Kramer, Christoph Lange, Ethan Lange, Leslie Lange, Cathy Laurie, Cecelia Laurie, Meryl LeBoff, Jiwon Lee, Sandra Lee, Wen-Jane Lee, Jonathon LeFaive, David Levine, Dan Levy, Joshua Lewis, Xiaohui Li, Yun Li, Henry Lin, Honghuang Lin, Xihong Lin, Simin Liu, Yu Liu, Ruth J.F. Loos, Steven Lubitz, Kathryn Lunetta, James Luo, Ulysses Magalang, Michael Mahaney, Barry Make, Ani Manichaikul, Alisa Manning, JoAnn Manson, Lisa Martin, Melissa Marton, Susan Mathai, Rasika Mathias, Susanne May, Patrick McArdle, Merry-Lynn McDonald, Sean McFarland, Stephen McGarvey, Daniel McGoldrick, Caitlin McHugh, Becky McNeil, Hao Mei, James Meigs, Vipin Menon, Luisa Mestroni, Ginger Metcalf, Deborah A. Meyers, Emmanuel Mignot, Julie Mikulla, Nancy Min, Mollie Minear, Ryan L. Minster, Braxton D. Mitchell, Matt Moll, Zeineen Momin, May E. Montasser, Courtney Montgomery, Donna Muzny, Josyf C. Mychaleckyj, Girish Nadkarni, Rakhi Naik, Take Naseri, Sergei Nekhai, Sarah C. Nelson, Bonnie Neltner, Caitlin Nessner, Deborah Nickerson, Osuji Nkechinyere, Kari North, Jeff O’Connell, Tim O’Connor, Heather Ochs-Balcom, Geoffrey Okwuonu, Allan Pack, David T. Paik, Nicholette Palmer, James Pankow, George Papanicolaou, Cora Parker, Gina Peloso, Juan Manuel Peralta, Marco Perez, James Perry, Ulrike Peters, Patricia Peyser, Lawrence S. Phillips, Jacob Pleiness, Toni Pollin, Wendy Post, Julia Powers Becker, Meher Preethi Boorgula, Michael Preuss, Bruce Psaty, Pankaj Qasba, Dandi Qiao, Zhaohui Qin, Nicholas Rafaels, Laura Raffield, Mahitha Rajendran, Vasan S. Ramachandran, D.C. Rao, Laura Rasmussen-Torvik, Aakrosh Ratan, Susan Redline, Robert Reed, Catherine Reeves, Elizabeth Regan, Alex Reiner, Muagututi’a Sefuiva Reupena, Ken Rice, Stephen Rich, Rebecca Robillard, Nicolas Robine, Dan Roden, Carolina Roselli, Jerome Rotter, Ingo Ruczinski, Alexi Runnels, Pamela Russell, Sarah Ruuska, Kathleen Ryan, Ester Cerdeira Sabino, Danish Saleheen, Shabnam Salimi, Sejal Salvi, Steven Salzberg, Kevin Sandow, Vijay G. Sankaran, Jireh Santibanez, Karen Schwander, David Schwartz, Frank Sciurba, Christine Seidman, Jonathan Seidman, Frédéric Sériès, Vivien Sheehan, Stephanie L. Sherman, Amol Shetty, Aniket Shetty, Wayne Hui-Heng Sheu, M. Benjamin Shoemaker, Brian Silver, Edwin Silverman, Robert Skomro, Albert Vernon Smith, Jennifer Smith, Josh Smith, Nicholas Smith, Tanja Smith, Sylvia Smoller, Beverly Snively, Michael Snyder, Tamar Sofer, Nona Sotoodehnia, Adrienne M. Stilp, Garrett Storm, Elizabeth Streeten, Jessica Lasky Su, Yun Ju Sung, Jody Sylvia, Adam Szpiro, Daniel Taliun, Hua Tang, Margaret Taub, Matthew Taylor, Simeon Taylor, Marilyn Telen, Timothy A. Thornton, Machiko Threlkeld, Lesley Tinker, David Tirschwell, Sarah Tishkoff, Hemant Tiwari, Catherine Tong, Russell Tracy, Michael Tsai, Dhananjay Vaidya, David Van Den Berg, Peter VandeHaar, Scott Vrieze, Tarik Walker, Robert Wallace, Avram Walts, Fei Fei Wang, Heming Wang, Jiongming Wang, Karol Watson, Jennifer Watt, Daniel E. Weeks, Joshua Weinstock, Bruce Weir, Scott T. Weiss, Lu-Chen Weng, Jennifer Wessel, Cristen Willer, Kayleen Williams, L. Keoki Williams, Carla Wilson, James Wilson, Lara Winterkorn, Quenna Wong, Joseph Wu, Huichun Xu, Lisa Yanek, Ivana Yang, Ketian Yu, Seyedeh Maryam Zekavat, Yingze Zhang, Snow Xueyan Zhao, Wei Zhao, Xiaofeng Zhu, Michael Zody, Sebastian Zoellner

المصدر: Circulation
Circulation, vol 145, iss 5

مصطلحات موضوعية: Adult, Male, Proteomics, Aging, Whole genome sequence analysis, Proteome, Clinical Sciences, Black People, Disease, Computational biology, race and ethnicity, Cardiorespiratory Medicine and Haematology, Cardiovascular, Article, proteomics, cardiovascular disease, Physiology (medical), Genetics, 2.1 Biological and endogenous factors, Humans, Medicine, Aetiology, Lung, Heart Disease - Coronary Heart Disease, and Blood Institute TOPMed (Trans-Omics for Precision Medicine) Consortium†, business.industry, Prevention, Human Genome, National Heart, Genomics, Blood proteins, Genetic architecture, Heart Disease, Good Health and Well Being, Cardiovascular System & Hematology, Cardiovascular Diseases, Public Health and Health Services, Female, Cardiology and Cardiovascular Medicine, business, Biotechnology, Genome-Wide Association Study

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::027a08b8289f9240dc2b3558b0b20fd1Test
https://doi.org/10.1161/circulationaha.121.055117Test

المؤلفون: Pi-Hua Liu, Hsiao-Lin Lee, Chen-Yang Shen, Chen-Hao Huang, Ru-Yi Tsai, Yi-Cheng Chang, Wei-Shun Yang, Meng-Lun Hsieh, Yu-Yao Huang, Chia-Ni Hsiung, Chia-Hung Lin, Chih-Neng Hsu, Jou-Wei Lin, Cassianne Robinson-Cohen, Tsui-Wei Chyan, Gwo-Tsann Chuang

المصدر: Scientific Reports, Vol 10, Iss 1, Pp 1-12 (2020)
Scientific Reports

مصطلحات موضوعية: 0301 basic medicine, Adult, Male, medicine.medical_specialty, FGF21, Taiwan, lcsh:Medicine, Genome-wide association study, Single-nucleotide polymorphism, Biology, Polymorphism, Single Nucleotide, Article, Body Mass Index, 03 medical and health sciences, PCSK9 Gene, 0302 clinical medicine, Endocrinology, Internal medicine, medicine, Genetics, SNP, Humans, Vitamin D, lcsh:Science, Gene, Aged, Multidisciplinary, lcsh:R, Middle Aged, TGFB2 Gene, Fibroblast Growth Factors, Fibroblast Growth Factor-23, 030104 developmental biology, Female, lcsh:Q, Body mass index, 030217 neurology & neurosurgery, Biomarkers, Genome-Wide Association Study

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66b3735c59972e44a584522b088b735eTest
http://link.springer.comTest/article/10.1038/s41598-020-71569-8

المؤلفون: George Hindy, Peter Dornbos, Mark D. Chaffin, Dajiang J. Liu, Minxian Wang, Margaret Sunitha Selvaraj, David Zhang, Joseph Park, Carlos A. Aguilar-Salinas, Lucinda Antonacci-Fulton, Diego Ardissino, Donna K. Arnett, Stella Aslibekyan, Gil Atzmon, Christie M. Ballantyne, Francisco Barajas-Olmos, Nir Barzilai, Lewis C. Becker, Lawrence F. Bielak, Joshua C. Bis, John Blangero, Eric Boerwinkle, Lori L. Bonnycastle, Erwin Bottinger, Donald W. Bowden, Matthew J. Bown, Jennifer A. Brody, Jai G. Broome, Noël P. Burtt, Brian E. Cade, Federico Centeno-Cruz, Edmund Chan, Yi-Cheng Chang, Yii-Der I. Chen, Ching-Yu Cheng, Won Jung Choi, Rajiv Chowdhury, Cecilia Contreras-Cubas, Emilio J. Córdova, Adolfo Correa, L. Adrienne Cupples, Joanne E. Curran, John Danesh, Paul S. de Vries, Ralph A. DeFronzo, Harsha Doddapaneni, Ravindranath Duggirala, Susan K. Dutcher, Patrick T. Ellinor, Leslie S. Emery, Jose C. Florez, Myriam Fornage, Barry I. Freedman, Valentin Fuster, Ma. Eugenia Garay-Sevilla, Humberto García-Ortiz, Soren Germer, Richard A. Gibbs, Christian Gieger, Benjamin Glaser, Clicerio Gonzalez, Maria Elena Gonzalez-Villalpando, Mariaelisa Graff, Sarah E. Graham, Niels Grarup, Leif C. Groop, Xiuqing Guo, Namrata Gupta, Sohee Han, Craig L. Hanis, Torben Hansen, Jiang He, Nancy L. Heard-Costa, Yi-Jen Hung, Mi Yeong Hwang, Marguerite R. Irvin, Sergio Islas-Andrade, Gail P. Jarvik, Hyun Min Kang, Sharon L.R. Kardia, Tanika Kelly, Eimear E. Kenny, Alyna T. Khan, Bong-Jo Kim, Ryan W. Kim, Young Jin Kim, Heikki A. Koistinen, Charles Kooperberg, Johanna Kuusisto, Soo Heon Kwak, Markku Laakso, Leslie A. Lange, Jiwon Lee, Juyoung Lee, Seonwook Lee, Donna M. Lehman, Rozenn N. Lemaitre, Allan Linneberg, Jianjun Liu, Ruth J.F. Loos, Steven A. Lubitz, Valeriya Lyssenko, Ronald C.W. Ma, Lisa Warsinger Martin, Angélica Martínez-Hernández, Rasika A. Mathias, Stephen T. McGarvey, Ruth McPherson, James B. Meigs, Thomas Meitinger, Olle Melander, Elvia Mendoza-Caamal, Ginger A. Metcalf, Xuenan Mi, Karen L. Mohlke, May E. Montasser, Jee-Young Moon, Hortensia Moreno-Macías, Alanna C. Morrison, Donna M. Muzny, Sarah C. Nelson, Peter M. Nilsson, Jeffrey R. O’Connell, Marju Orho-Melander, Lorena Orozco, Colin N.A. Palmer, Nicholette D. Palmer, Cheol Joo Park, Kyong Soo Park, Oluf Pedersen, Juan M. Peralta, Patricia A. Peyser, Wendy S. Post, Michael Preuss, Bruce M. Psaty, Qibin Qi, D.C. Rao, Susan Redline, Alexander P. Reiner, Cristina Revilla-Monsalve, Stephen S. Rich, Nilesh Samani, Heribert Schunkert, Claudia Schurmann, Daekwan Seo, Jeong-Sun Seo, Xueling Sim, Rob Sladek, Kerrin S. Small, Wing Yee So, Adrienne M. Stilp, E. Shyong Tai, Claudia H.T. Tam, Kent D. Taylor, Yik Ying Teo, Farook Thameem, Brian Tomlinson, Michael Y. Tsai, Tiinamaija Tuomi, Jaakko Tuomilehto, Teresa Tusié-Luna, Miriam S. Udler, Rob M. van Dam, Ramachandran S. Vasan, Karine A. Viaud Martinez, Fei Fei Wang, Xuzhi Wang, Hugh Watkins, Daniel E. Weeks, James G. Wilson, Daniel R. Witte, Tien-Yin Wong, Lisa R. Yanek, Sekar Kathiresan, Daniel J. Rader, Jerome I. Rotter, Michael Boehnke, Mark I. McCarthy, Cristen J. Willer, Pradeep Natarajan, Jason A. Flannick, Amit V. Khera, Gina M. Peloso

المساهمون: NIH - National Heart, Lung, and Blood Institute (NHLBI) (Estados Unidos), Centre of Excellence in Complex Disease Genetics, HUS Abdominal Center, Institute for Molecular Medicine Finland, Leif Groop Research Group, Clinicum, Department of Medicine, HUS Internal Medicine and Rehabilitation, University of Helsinki, Department of Public Health

المصدر: Hindy, G, Dornbos, P, Chaffin, M D, Liu, D J, Wang, M, Selvaraj, M S, Zhang, D, Park, J, Aguilar-Salinas, C A, Antonacci-Fulton, L, Ardissino, D, Arnett, D K, Aslibekyan, S, Atzmon, G, Ballantyne, C M, Barajas-Olmos, F, Barzilai, N, Becker, L C, Bielak, L F, Bis, J C, Blangero, J, Boerwinkle, E, Bonnycastle, L L, Bottinger, E, Bowden, D W, Bown, M J, Brody, J A, Broome, J G, Burtt, N P, Cade, B E, Centeno-Cruz, F, Chan, E, Chang, Y C, Chen, Y D I, Cheng, C Y, Choi, W J, Chowdhury, R, Contreras-Cubas, C, Córdova, E J, Correa, A, Cupples, L A, Curran, J E, Danesh, J, de Vries, P S, Grarup, N, Hansen, T, Linneberg, A, Loos, R J F, Pedersen, O, Witte, D R, AMP-T2D-GENES, Myocardial Infarction Genetics Consortium, NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium & NHLBI TOPMed Lipids Working Group 2022, ' Rare coding variants in 35 genes associate with circulating lipid levels-A multi-ancestry analysis of 170,000 exomes ', American Journal of Human Genetics, vol. 109, no. 1, pp. 81-96 . https://doi.org/10.1016/j.ajhg.2021.11.021Test
Am J Hum Genet
Hindy, G, Dornbos, P, Chaffin, M D, Liu, D J, Wang, M, Selvaraj, M S, Zhang, D, Park, J, Aguilar-Salinas, C A, Antonacci-Fulton, L, Ardissino, D, Arnett, D K, Aslibekyan, S, Atzmon, G, Ballantyne, C M, Barajas-Olmos, F, Barzilai, N, Becker, L C, Bielak, L F, Bis, J C, Blangero, J, Boerwinkle, E, Bonnycastle, L L, Bottinger, E, Bowden, D W, Bown, M J, Brody, J A, Broome, J G, Burtt, N P, Cade, B E, Centeno-Cruz, F, Chan, E, Chang, Y C, Chen, Y D I, Cheng, C Y, Choi, W J, Chowdhury, R, Contreras-Cubas, C, Córdova, E J, Correa, A, Cupples, L A, Curran, J E, Danesh, J, de Vries, P S, DeFronzo, R A, Grarup, N, Hansen, T, Pedersen, O, Wang, F F, Witte, D R, AMP-T2D-GENES, Myocardial Infarction Genetics Consortium, NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium & NHLBI TOPMed Lipids Working Group 2022, ' Rare coding variants in 35 genes associate with circulating lipid levels—A multi-ancestry analysis of 170,000 exomes ', American Journal of Human Genetics, vol. 109, no. 1, pp. 81-96 . https://doi.org/10.1016/j.ajhg.2021.11.021Test
Hindy, G, Dornbos, P, Chaffin, M D, Liu, D J, Wang, M, Selvaraj, M S, Zhang, D, Park, J, Aguilar-Salinas, C A, Antonacci-Fulton, L, Ardissino, D, Arnett, D K, Aslibekyan, S, Atzmon, G, Ballantyne, C M, Barajas-Olmos, F, Barzilai, N, Becker, L C, Bielak, L F, Bis, J C, Blangero, J, Boerwinkle, E, Bonnycastle, L L, Bottinger, E, Bowden, D W, Bown, M J, Brody, J A, Broome, J G, Burtt, N P, Cade, B E, Centeno-Cruz, F, Chan, E, Chang, Y-C, Chen, Y-D I, Cheng, C-Y, Choi, W J, Chowdhury, R, Contreras-Cubas, C, Córdova, E J, Correa, A, Cupples, L A, Curran, J E, Danesh, J, de Vries, P S, DeFronzo, R A, Doddapaneni, H, Duggirala, R, Dutcher, S K, Ellinor, P T, Grarup, N, Hansen, T, Pedersen, O, Linneberg, A, Witte, D R & AMP-T2D-GENES, Myocardial Infarction Genetics Consortium 2022, ' Rare coding variants in 35 genes associate with circulating lipid levels-A multi-ancestry analysis of 170,000 exomes ', American Journal of Human Genetics, vol. 109, no. 1, pp. 81-96 . https://doi.org/10.1016/j.ajhg.2021.11.021Test

مصطلحات موضوعية: APOC3, Blood Glucose, Multifactorial Inheritance, gene-based association, Polymorphism, Single Nucleotide, Article, Open Reading Frames, ANGPTL3, lipid, OF-FUNCTION MUTATIONS, BINDING, Databases, Genetic, SEQUENCE VARIANTS, Genetics, Humans, Exome, Genetic Predisposition to Disease, SINUSOIDAL ENDOTHELIAL-CELLS, Genetics (clinical), Alleles, RISK, IDENTIFICATION, 1184 Genetics, developmental biology, physiology, association, cholesterol, Genetic Variation, Computational Biology, Molecular Sequence Annotation, PERILIPIN, Lipid Metabolism, Lipids, Genetics, Population, Phenotype, Diabetes Mellitus, Type 2, Liver, Case-Control Studies, exome sequencing, TRIGLYCERIDES, Genome-Wide Association Study

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d53d518c5a9781ccf6a21517fa2887b9Test
https://hdl.handle.net/20.500.12105/15626Test

المؤلفون: Sheng-Nan Chang, Jien-Jiun Chen, Jo-Hsuan Wu, Yao-Te Chung, Jin-Wun Chen, Chu-Hsuan Chiu, Chia-Ju Liu, Meng-Tsun Liu, Yi-Cheng Chang, Chin Li, Jou-Wei Lin, Juey-Jen Hwang, Wen-Pin Lien

المصدر: Cells; Volume 11; Issue 1; Pages: 98
Cells
Cells, Vol 11, Iss 98, p 98 (2022)

مصطلحات موضوعية: Male, QH301-705.5, High-Throughput Nucleotide Sequencing, General Medicine, Coronary Artery Disease, exosomes, Middle Aged, Article, MicroRNAs, micro RNAs, Linear Models, Humans, Female, next-generation sequencing, cardiovascular diseases, Biology (General), coronary artery disease, Aged

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29f88d2b398e011fd00fda5aed56289aTest

المؤلفون: Yih Giun Cherng, Chun-Chuan Shih, Yi-Cheng Chang, Chien-Chang Liao, Chun Chieh Yeh, Chao-Shun Lin, Ta-Liang Chen, Chun-Cheng Li, Chaur-Jong Hu, Chuen Chau Chang

المصدر: Scientific Reports
Scientific Reports, Vol 11, Iss 1, Pp 1-7 (2021)

مصطلحات موضوعية: Adult, Male, medicine.medical_specialty, Databases, Factual, Science, Taiwan, Diseases, Risk Assessment, Article, Young Adult, Epilepsy, Endocrinology, Patient Admission, Risk Factors, Sepsis, Internal medicine, Diabetes mellitus, Diabetes Mellitus, medicine, Humans, Adverse effect, Aged, Proportional Hazards Models, Retrospective Studies, Aged, 80 and over, Multidisciplinary, business.industry, Incidence, Hazard ratio, Health care, Pneumonia, Odds ratio, Middle Aged, medicine.disease, Confidence interval, Case-Control Studies, Urinary Tract Infections, Cohort, Medicine, Female, business, Follow-Up Studies, Cohort study

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::402567440114c081c5a969339fe78eceTest
https://doi.org/10.1038/s41598-021-98340-xTest

المؤلفون: Gabriel M. Hauswirth, Victoria C. Garside, Lisa S. F. Wong, Heidi Bildsoe, Jan Manent, Yi-Cheng Chang, Christian M. Nefzger, Jaber Firas, Joseph Chen, Fernando J. Rossello, Jose M. Polo, Edwina McGlinn

المصدر: Nature Communications
Nature Communications, Vol 13, Iss 1, Pp 1-12 (2022)

مصطلحات موضوعية: Homeodomain Proteins, Mammals, Tail, Multidisciplinary, Science, Soft materials, Genes, Homeobox, General Physics and Astronomy, Tretinoin, General Chemistry, Biological Evolution, General Biochemistry, Genetics and Molecular Biology, Spine, Article, Growth Differentiation Factors, Mice, MicroRNAs, Engineering, Bone Morphogenetic Proteins, Animals, Transcriptome, Body Patterning

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::185bc1c180d5f59b2f31e437b02087cdTest
https://pubmed.ncbi.nlm.nih.gov/35017475Test

المؤلفون: Jiang He, Ruth Loos, Stephanie Gogarten, C. Charles Gu, Alexi Runnels, Xiuwen Zheng, Pradeep Natarajan, Vipin Menon, James Pankow, Matthew Conomos, Karin Hoth, Joanne Curran, Marilyn Telen, Jennifer Body, Gregory Kinney, Tamar Sofer, Zeineen Momin, Frank Sciurba, Stephen Rich, Yi-Cheng Chang, Albert Vernon Smith, LEE-MING CHUANG, Harshavardhan Doddapaneni

المصدر: Nature communications, vol 12, iss 1
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)

مصطلحات موضوعية: 0301 basic medicine, Statistical methods, Science, General Physics and Astronomy, Genome-wide association study, 030105 genetics & heredity, Biology, Population stratification, Genome-wide association studies, Article, General Biochemistry, Genetics and Molecular Biology, Statistical power, 03 medical and health sciences, NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium, Gene Frequency, Genetics research, Statistics, False positive paradox, Genetics, Humans, Computer Simulation, Allele frequency, Genetic association, Multidisciplinary, Human Genome, Genetic Variation, General Chemistry, Variance (accounting), 030104 developmental biology, Phenotype, Good Health and Well Being, Sample size determination, Sample Size, Next-generation sequencing, Generic health relevance, Algorithms, Genome-Wide Association Study

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a8b1b6f4880c565e1a53c0af90309c4Test
https://escholarship.org/uc/item/98x5h10tTest

المؤلفون: Albertine J. Oldehinkel, Wieland Kiess, Xueling Sim, Norihiro Kato, Philippe Froguel, Astrid van Hylckama Vlieg, Josée Dupuis, Nanette R. Lee, Symen Ligthart, Harry Campbell, Marta E. Alarcón-Riquelme, P. Eline Slagboom, Massimo Mangino, Tian Xie, Niek Verweij, James B. Meigs, Chaolong Wang, Michael Y. Tsai, Erik Ingelsson, Colin N. A. Palmer, Erik B. van den Akker, Fumihiko Matsuda, Rainer Rauramaa, Yi-Cheng Chang, Lars Lind, Stefan R. Bornstein, Mandy Vogel, Sven Bergmann, Ya X. Wang, Ching-Ti Liu, Annette Schürmann, Michael Boehnke, David J. Porteous, Kazuya Setoh, Qibin Qi, Ayse Demirkan, Francesco Cucca, Allan Linneberg, Claire J. Steves, Jun Liu, Leslie A. Lange, Noël P. Burtt, Diana Kuh, Cassandra N. Spracklen, Ken K. Ong, Charumathi Sabanayagam, Jost B. Jonas, Ele Ferrannini, Lawrence J. Beilin, Qing Duan, Blair H. Smith, Isobel D. Stewart, Alexander P. Reiner, Simon P. Mooijaart, Tim D. Spector, Paul W. Franks, E. Shyong Tai, Mark I. McCarthy, Anna L. Gloyn, D.I. Boomsma, Dennis Raven, Nicholas J. Timpson, Rona J. Strawbridge, George Dedoussis, Susan Redline, Jaeyoung Hong, Harald Grallert, Jagadish Vangipurapu, Rico Rueedi, Diane M. Becker, Marian Beekman, Claudia P. Cabrera, Johannes Waage, Jin Fang Chai, Yii-Der Ida Chen, Graciela E. Delgado, Thibaud S. Boutin, Yang Hai, Yoriko Heianza, Wei Zhao, Andres Metspalu, Tien Yin Wong, Mila Desi Anasanti, Inger Njølstad, Hans Bisgaard, Valeriya Lyssenko, Denis Rybin, Wanqing Wen, Torben Hansen, James F. Wilson, Sameline Grimsgaard, Annette Peters, Michele K. Evans, Damia Noce, Sarah C. Nelson, May E. Montasser, Nan Wang, Geltrude Mingrone, Gudny Eiriksdottir, Nicholas J. Wareham, Fouad Kandeel, Linda S. Adair, Kelvin Lam, Jaana Lindström, Eco J. C. de Geus, Debbie A Lawlor, Sara M. Willems, Xu Lin, Harold Snieder, Matt J. Neville, Naveed Sattar, Chelsea K. Raulerson, Paul M. Ridker, Jer-Yuarn Wu, Weihua Zhang, H. Janaka de Silva, Jana V. van Vliet-Ostaptchouk, Elena Tremoli, Toru Nabika, Jing Hua Zhao, Vilmundur Gudnason, Tao Huang, Robert C. Kaplan, Sohee Han, Mohammad Hadi Zafarmand, Aaron Leong, Yen-Feng Chiu, Kumaraswamy Naidu Chitrala, Ivana Kolcic, Franco Giulianini, Tao Wang, Lu Qi, Stephan J. L. Bakker, Laura J Corbin, Zoltán Kutalik, Bruna Gigante, Willa A. Hsueh, Peter J. van der Most, Tin Louie, Yujie Wang, Stella Trompet, Fernando Rivideneira, Yasumasa Ohyagi, Lynne E. Wagenknecht, Jerry L. Nadler, Michael Stumvoll, Mark O. Goodarzi, Sahoko Ichihara, Jeffrey R. O'Connell, Tomohiro Katsuya, Giorgio Pistis, Alice Stanton, Sirkka Keinänen-Kiukaanniemi, Momoko Horikoshi, Honglan Li, Tanja G. M. Vrijkotte, Caroline Hayward, Karen L. Mohlke, Carola Marzi, Girish N. Nadkarni, Laura J. Rasmussen-Torvik, Alain G. Bertoni, Andrew R. Wood, Annique Claringbould, Mi Yeong Hwang, Hugh Watkins, Heikki A. Koistinen, Mattias Frånberg, Jani Heikkinen, Elizabeth Selvin, Donald W. Bowden, Abbas Dehghan, Christian Fuchsberger, Audrey Y. Chu, Kent D. Taylor, Katherine A. Kentistou, Johanna Kuusisto, Jingyi Tan, Huaixing Li, Eric Boerwinkle, Catharina A. Hartman, Archie Campbell, Kari E. North, Oluf Pedersen, Sölve Elmståhl, Emil V. R. Appel, Chang-Hsun Hsieh, Dennis O. Mook-Kanamori, Rob M. van Dam, Pontiano Kaleebu, Corri Black, Jennifer A. Brody, Bengt Sennblad, Shaofeng Huo, M. Larissa Avilés-Santa, Ruth J. F. Loos, Patricia B. Munroe, Chien-Hsiun Chen, Liang Sun, Zorayr Arzumanyan, Rebecca Rohde, Yasuharu Tabara, Albert V. Smith, Betina H. Thuesen, Niels Grarup, Jorgen Engmann, Tatijana Zemunik, M. Arfan Ikram, Marit E. Jørgensen, Christian Herder, Ching-Yu Cheng, Serena Sanna, Damiano Baldassarre, Tarunveer S. Ahluwalia, Mark J. Caulfield, Anne Ndungu, Carl D. Langefeld, Lisa R. Yanek, Luigi Ferrucci, Ananda R. Wickremasinghe, Raymond Noordam, Trevor A. Mori, Tom Wilsgaard, Mika Kivimäki, Rita R. Kalyani, Alan B. Zonderman, Veronique Vitart, Patricia A. Peyser, Shuiqing Lai, Richa Saxena, Li-Ching Chang, Karin Leander, Wei Huang, Peter Vollenweider, Tanya M. Teslovich, Ying Wu, Shufa Du, Brian E. Cade, Patrik K. E. Magnusson, John C. Chambers, Stephen C. J. Parker, Tamar Sofer, Winfried März, Sharon L.R. Kardia, Peter K. Joshi, Neil R. Robertson, Anny H. Xiang, Fumihiko Takeuchi, N. Amin, Jouke-Jan Hottenga, Carol A. Wang, Stefan Gustafsson, Jung Ho Gong, Penny Gordon-Larsen, Yu-Tang Gao, Abhishek Nag, Gonneke Willemsen, Michael A. Province, Aliki-Eleni Farmaki, Segun Fatumo, Antje Körner, Pim van der Harst, Marie Loh, Kei Hang Katie Chan, Gonçalo R. Abecasis, Nicholette D. Palmer, Simin Liu, Ishminder K. Kooner, Javier Gayán, Arne Astrup, Laura J. Scott, Erwin P. Bottinger, Andrew Wong, Inga Prokopenko, Ping An, Markku Laakso, Matthias Blüher, Susan R. Heckbert, Thomas A. Buchanan, Tatsuaki Matsubara, Andrew P. Morris, Brian H. Chen, Kristi Läll, Teresa Tusie, Timo A. Lakka, Jie Yao, Michael Preuss, Teemu Kuulasmaa, Carlos Lorenzo, Stephen S. Rich, Marie Lauzon, Laura M. Raffield, Pankow S. James, Takahisa Kawaguchi, Kathleen A. Ryan, Wei Zheng, Igor Rudan, Thomas Sparsø, Hugoline G. de Haan, Sandosh Padmanabhan, Richard M. Watanabe, Alicia Huerta-Chagoya, Anette P. Gjesing, Andrew A. Hicks, Richard N. Bergman, Mitsuhiro Yokota, Heather M. Stringham, Bruce M. Psaty, Jian'an Luan, Anuj Goel, Eleanor Wheeler, Masahiro Nakatochi, Young-Jin Kim, Xiao-Ou Shu, Mickaël Canouil, Robert A. Scott, Marika Kaakinen, Mari Nelis, Adolfo Correa, Jaspal S. Kooner, Michiya Igase, Anubha Mahajan, Peter E. H. Schwarz, Craig E. Pennell, Claudia Schurmann, Xiaoran Chai, Ji Chen, Lori L. Bonnycastle, Peter S. Sever, Thorkild I. A. Sørensen, André G. Uitterlinden, Ilja M. Nolte, Gaëlle Marenne, Timothy M. Frayling, Bong-Jo Kim, Kerrin S. Small, Cecilia M. Lindgren, Bernhard O. Böhm, Shih-Yi Lin, Katharina E. Schraut, Cornelia M. van Duijn, Sanghoon Moon, Mark Walker, Chiea Chuen Khor, Ruifang Li-Gao, Qiuyin Cai, Neil Schneiderman, Ko Willems van Dijk, Ozren Polasek, W. Craig Johnson, Dermot F. Reilly, Inês Barroso, Anke Tönjes, Manjinder S. Sandhu, Wen B. Wei, Jose C. Florez, Lorraine Southam, Leif Groop, Lawrence F. Bielak, Peter Kovacs, Jianjun Liu, Jouko Saramies, Helen R. Warren, Man Li, Daniel I. Chasman, Eleftheria Zeggini, Xiaoshuai Zhang, Loic Yengo, Shi Jinxiu, Jirong Long, Xiuqing Guo, Meena Kumari, Leslie J. Raffel, Jill M. Norris, Henrik Vestergaard, Jing He, Peter P. Pramstaller, Diana van Heemst, Kevin Sandow, Marjo-Ritta Jarvelin, Carlos A. Aguilar-Salinas, Peitao Wu, Hortensia Moreno-Macías, Jerome I. Rotter, Kathryn Roll, Frits R. Rosendaal, Bernardo L. Horta, Heming Wang, Fernando Pires Hartwig, Richard A. Jensen, Matti Uusitupa, Rozenn N. Lemaitre, Paul R. H. J. Timmers, Timo Saaristo, Jaakko Tuomilehto, Reedik Mägi, Debashree Ray, J. Wouter Jukema, Claudia Langenberg, Marcus E. Kleber, Francis S. Collins, Klaus Bønnelykke, Lenore J. Launer, Arushi Varshney, Anders Hamsten

المساهمون: European Commission, Génétique, génomique fonctionnelle et biotechnologies (UMR 1078) (GGB), Institut Brestois Santé Agro Matière (IBSAM), Université de Brest (UBO)-Université de Brest (UBO)-EFS-Institut National de la Santé et de la Recherche Médicale (INSERM), Sanger Institute, Wellcome Trust, Marenne, Gaëlle [0000-0002-4363-7170], Varshney, Arushi [0000-0001-9177-9707], Corbin, Laura J [0000-0002-4032-9500], Parker, Stephen CJ [0000-0001-8122-0117], Langenberg, Claudia [0000-0002-5017-7344], Wheeler, Eleanor [0000-0002-8616-6444], Morris, Andrew P [0000-0002-6805-6014], Barroso, Inês [0000-0001-5800-4520], Apollo - University of Cambridge Repository, Lifelines Cohort Study, Meta-Analysis of Glucose and Insulin-related Traits Consortium (MAGIC), de Haan, H.G., van den Akker, E., van der Most, P.J., de Geus, EJC, van Dam, R.M., van Heemst, D., van Hylckama Vlieg, A., van Willems van Dijk, K., de Silva, H.J., van der Harst, P., van Duijn, C., Centre of Excellence in Complex Disease Genetics, HUS Abdominal Center, Institute for Molecular Medicine Finland, Leif Groop Research Group, HUS Internal Medicine and Rehabilitation, Department of Medicine, Department of Biochemistry and Developmental Biology, Helsinki University Hospital Area, University of Helsinki, Clinicum, Department of Public Health, Biological Psychology, APH - Health Behaviors & Chronic Diseases, APH - Personalized Medicine, Physiology, AMS - Musculoskeletal Health, AMS - Tissue Function & Regeneration, APH - Mental Health, Nutrition and Health, APH - Methodology, Epidemiology and Data Science, ACS - Atherosclerosis & ischemic syndromes, APH - Aging & Later Life, ARD - Amsterdam Reproduction and Development, Public and occupational health, Epidemiology, Internal Medicine, Life Course Epidemiology (LCE), Groningen Institute for Gastro Intestinal Genetics and Immunology (3GI), Groningen Institute for Organ Transplantation (GIOT), Groningen Kidney Center (GKC), Interdisciplinary Centre Psychopathology and Emotion regulation (ICPE), Center for Liver, Digestive and Metabolic Diseases (CLDM), Cardiovascular Centre (CVC)

المصدر: Nature Genetics
Nature Genetics, Nature Publishing Group, 2021, ⟨10.1038/s41588-021-00852-9⟩
Lifelines Cohort Study & Meta-Analysis of Glucose and Insulin-related Traits Consortium (MAGIC) 2021, ' The trans-ancestral genomic architecture of glycemic traits ', Nature Genetics, vol. 53, no. 6, pp. 840-860 . https://doi.org/10.1038/s41588-021-00852-9Test
Nature genetics, vol. 53, no. 6, pp. 840-860
Chen, J, Spracklen, C N, Marenne, G, Varshney, A, Corbin, L J, Luan, J, Willems, S M, Wu, Y, Zhang, X, Horikoshi, M, Boutin, T S, Magi, R, Waage, J, Li-Gao, R, Chan, K H K, Yao, J, Anasanti, M D, Chu, A Y, Claringbould, A, Heikkinen, J, Hong, J, Hottenga, J-J, Huo, S, Kaakinen, M A, Louie, T, Maerz, W, Moreno-Macias, H, Ndungu, A, Nelson, S C, Nolte, I M, North, K E, Appel, E V R, Liu, J, Sparso, T, Zhao, J-H, Astrup, A, Jørgensen, M E, Linneberg, A, Vestergaard, H, Bisgaard, H, Bønnelykke, K, Grarup, N, Hansen, T, Kovacs, P, Lind, L, Loos, R J F, Njølstad, I, Pedersen, O, Schwarz, P, Sorensen, T I A & Meta-Analysis of Glucose and Insulin-Related Trait Consortium (MAGIC) 2021, ' The trans-ancestral genomic architecture of glycemic traits ', Nature Genetics, vol. 53, no. 6, pp. 840-860 . https://doi.org/10.1038/s41588-021-00852-9Test
Nature genetics
Nature Genetics, 53(6), 840-860. NATURE RESEARCH
Chen, J, Spracklen, C N, Marenne, G, Varshney, A, Corbin, L J, Hottenga, J, De Geus, E J C, Van Dam, R M, Boomsma, D I, Vrijkotte, T G M, Willemsen, G & MAGIC Investigators 2021, ' The trans-ancestral genomic architecture of glycemic traits ', Nature Genetics, vol. 53, no. 6, pp. 840-860 . https://doi.org/10.1038/s41588-021-00852-9Test
2021, ' The trans-ancestral genomic architecture of glycemic traits ', Nature Genetics, vol. 53 . https://doi.org/10.1038/s41588-021-00852-9Test
Nature Genetics, 53(6), 840-860. Nature Publishing Group
Nature genetics, 53(6), 840-860. Nature Publishing Group
Corbin, L J, Timpson, N J, Lawlor, D A, Barroso, I & et al. 2021, ' The Trans-Ancestral Genomic Architecture of Glycemic Traits ', Nature Genetics, vol. 53, no. 6, pp. 840-860 . https://doi.org/10.1038/s41588-021-00852-9Test
Nature Genetics, 53, 840-860. Nature Publishing Group

مصطلحات موضوعية: Blood Glucose, Disease risk, Multifactorial Inheritance, Glycated Hemoglobin A, [SDV]Life Sciences [q-bio], Meta-Analysis of Glucose and Insulin-related Traits Consortium (MAGIC), LOCI, Genome-wide association study, Type 2 diabetes, VARIANTS, GLUCOSE, Epigenesis, Genetic, chemistry.chemical_compound, 0302 clinical medicine, Mechanisms, WIDE ASSOCIATION, genetics, Gene-expression, HEMOGLOBIN, ComputingMilieux_MISCELLANEOUS, 11 Medical and Health Sciences, GENE-EXPRESSION, Genetics, Genetics & Heredity, 0303 health sciences, INSULIN-RESISTANCE, Genome, Loci, 1184 Genetics, developmental biology, physiology, Variants, ALSPAC, Physical Chromosome Mapping, Life Sciences & Biomedicine, Human, Quantitative Trait Loci, Wide association study, Biology, Quantitative trait locus, Article, White People, diseases, MECHANISMS, Quantitative Trait, 03 medical and health sciences, Insulin resistance, Quantitative Trait, Heritable, SDG 3 - Good Health and Well-being, Genetic, Lifelines Cohort Study, Diabetes mellitus, medicine, Humans, Hemoglobin, Heritable, METAANALYSIS, Alleles, 030304 developmental biology, Genetic association, Glycemic, Glycated Hemoglobin, Science & Technology, Genome, Human, Whites, Gene Expression Profiling, DISEASE RISK, Settore MED/13 - ENDOCRINOLOGIA, Insulin-resistance, 06 Biological Sciences, medicine.disease, Glucose, chemistry, Blood Glucose/genetics, European Continental Ancestry Group/genetics, Genome-Wide Association Study, Glycated Hemoglobin A/metabolism, Multifactorial Inheritance/genetics, Quantitative Trait Loci/genetics, Glycated hemoglobin, 030217 neurology & neurosurgery, Meta analysis, Epigenesis, Developmental Biology

وصف الملف: application/pdf; application/vnd.openxmlformats-officedocument.spreadsheetml.sheet; Print-Electronic

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dfd7b30b504793e1c50aff861c4059faTest
http://hdl.handle.net/10044/1/98553Test

المؤلفون: Dan Mishmar, Douglas C. Wallace, Olga Derbeneva, Larry N. Singh, Dimitra Chalkia, Lee-Ming Chuang, Yi-Cheng Chang, Xiaogang Liu, Ping H. Wang, Maria Lvova

المصدر: Biochimica et biophysica acta. Bioenergetics, vol 1859, iss 9

مصطلحات موضوعية: Male, 0301 basic medicine, Pedigree chart, Eastern, medicine.disease_cause, Biochemistry, Haplogroup, Gene duplication, 2.1 Biological and endogenous factors, Aetiology, Metabolic Syndrome, Genetics, Mutation, mtDNA, Asia, Eastern, Diabetes, Single Nucleotide, Middle Aged, humanities, Mitochondrial, Mitochondria, Pedigree, Phenotype, Female, Type 2, Physical Chemistry (incl. Structural), Adult, Cybrids, Mitochondrial DNA, Asia, Biophysics, Biology, DNA, Mitochondrial, Polymorphism, Single Nucleotide, Article, 03 medical and health sciences, Asian People, Diabetes Mellitus, medicine, Humans, Obesity, Polymorphism, Risk factor, Metabolic and endocrine, Nutrition, nutritional and metabolic diseases, DNA, social sciences, Cell Biology, medicine.disease, eye diseases, 030104 developmental biology, Diabetes Mellitus, Type 2, Haplotypes, Case-Control Studies, Biochemistry and Cell Biology, Metabolic syndrome, Human mitochondrial DNA haplogroup

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8dd9665760fdb958fb41606487468a7Test
https://doi.org/10.1016/j.bbabio.2018.07.002Test

المؤلفون: Pradeep Natarajan, Akhil Pampana, Sarah E. Graham, Sanni E. Ruotsalainen, James A. Perry, Paul S. de Vries, Jai G. Broome, James P. Pirruccello, Michael C. Honigberg, Krishna Aragam, Brooke Wolford, Jennifer A. Brody, Lucinda Antonacci-Fulton, Moscati Arden, Stella Aslibekyan, Themistocles L. Assimes, Christie M. Ballantyne, Lawrence F. Bielak, Joshua C. Bis, Brian E. Cade, Ron Do, Harsha Doddapaneni, Leslie S. Emery, Yi-Jen Hung, Marguerite R. Irvin, Alyna T. Khan, Leslie Lange, Jiwon Lee, Rozenn N. Lemaitre, Lisa W. Martin, Ginger Metcalf, May E. Montasser, Jee-Young Moon, Donna Muzny, Jeffrey R. O’Connell, Nicholette D. Palmer, Juan M. Peralta, Patricia A. Peyser, Adrienne M. Stilp, Michael Tsai, Fei Fei Wang, Daniel E. Weeks, Lisa R. Yanek, James G. Wilson, Goncalo Abecasis, Donna K. Arnett, Lewis C. Becker, John Blangero, Eric Boerwinkle, Donald W. Bowden, Yi-Cheng Chang, Yii-Der I. Chen, Won Jung Choi, Adolfo Correa, Joanne E. Curran, Mark J. Daly, Susan K. Dutcher, Patrick T. Ellinor, Myriam Fornage, Barry I. Freedman, Stacey Gabriel, Soren Germer, Richard A. Gibbs, Jiang He, Kristian Hveem, Gail P. Jarvik, Robert C. Kaplan, Sharon L. R. Kardia, Eimear Kenny, Ryan W. Kim, Charles Kooperberg, Cathy C. Laurie, Seonwook Lee, Don M. Lloyd-Jones, Ruth J. F. Loos, Steven A. Lubitz, Rasika A. Mathias, Karine A. Viaud Martinez, Stephen T. McGarvey, Braxton D. Mitchell, Deborah A. Nickerson, Kari E. North, Aarno Palotie, Cheol Joo Park, Bruce M. Psaty, D. C. Rao, Susan Redline, Alexander P. Reiner, Daekwan Seo, Jeong-Sun Seo, Albert V. Smith, Russell P. Tracy, Ramachandran S. Vasan, Sekar Kathiresan, L. Adrienne Cupples, Jerome I. Rotter, Alanna C. Morrison, Stephen S. Rich, Samuli Ripatti, Cristen Willer, NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium, FinnGen, Gina M. Peloso

المساهمون: Institute for Molecular Medicine Finland, Samuli Olli Ripatti / Principal Investigator, Complex Disease Genetics, Centre of Excellence in Complex Disease Genetics, Research Programs Unit, Aarno Palotie / Principal Investigator, Genomics of Neurological and Neuropsychiatric Disorders, Department of Public Health, Biostatistics Helsinki, Department of Clinical Chemistry and Hematology, Doctoral Programme in Social Sciences, HYKS erva, Päijät-Häme Welfare Consortium, Department of Medicine, HUS Inflammation Center, Clinicum, HUS Heart and Lung Center, Marja-Riitta Taskinen Research Group, Tiinamaija Tuomi Research Group, HUS Abdominal Center, Department of Oncology, Heikki Joensuu / Principal Investigator, HUS Comprehensive Cancer Center, Department of Medical and Clinical Genetics, Lauri Antti Aaltonen / Principal Investigator, HUS Head and Neck Center, Silmäklinikka, Department of Dermatology, Allergology and Venereology, Department of Food and Nutrition, Medicum, Data Science Genetic Epidemiology Lab, HUSLAB, Department of Mathematics and Statistics, University Management, Biosciences, Pregnancy and Genes, HUS Gynecology and Obstetrics

المصدر: Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)

مصطلحات موضوعية: 0301 basic medicine, Male, Apolipoprotein B, General Physics and Astronomy, Blood lipids, Adipose tissue, Genome-wide association study, 030204 cardiovascular system & hematology, Genome-wide association studies, PCSK9, 0302 clinical medicine, Subcutaneous Tissue, GENETIC-VARIANTS, Phenomics, X chromosome, RISK, Multidisciplinary, biology, 1184 Genetics, developmental biology, physiology, Middle Aged, Lipids, X-CHROMOSOME, CORONARY-ARTERY-DISEASE, Female, medicine.medical_specialty, CHOLESTEROL/APOLIPOPROTEIN-B RATIO, APOLIPOPROTEIN-B, Genotype, Science, Nerve Tissue Proteins, Polymorphism, Single Nucleotide, General Biochemistry, Genetics and Molecular Biology, Article, 03 medical and health sciences, Diabetes mellitus, Internal medicine, medicine, Humans, Genetic Predisposition to Disease, GENOME-WIDE ASSOCIATION, Allele, Eye Proteins, Genetic Association Studies, Chromosomes, Human, X, DENSITY-LIPOPROTEIN-CHOLESTEROL, Whole Genome Sequencing, business.industry, Cardiometabolic Risk Factors, FAT DISTRIBUTION, General Chemistry, Cardiovascular genetics, medicine.disease, 030104 developmental biology, Endocrinology, Gene Expression Regulation, Genetic Loci, biology.protein, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9f5d93ee105f4a0e18899e311053c6cTest
https://pubmed.ncbi.nlm.nih.gov/33846329Test