نتائج البحث - "Xueyong Zhu"

1

Structural and functional ramifications of antigenic drift in recent SARS-CoV-2 variants

المؤلفون: Nicholas C. Wu, Xueyong Zhu, Marit J. van Gils, Jakob Kreye, Chang-Chun D Lee, Linghang Peng, Hejun Liu, Meng Yuan, Abigail M. Jackson, Dennis R. Burton, Andrew B. Ward, Rogier W. Sanders, David Nemazee, S. Momsen Reincke, Harald Prüss, Ian A. Wilson, Deli Huang

المساهمون: Medical Microbiology and Infection Prevention, AII - Infectious diseases

المصدر: Science 373(6556), 818-823 (2021). doi:10.1126/science.abh1139
bioRxiv
article-version (status) pre
article-version (number) 1
Science, 373(6556), 818-823. American Association for the Advancement of Science
Science (New York, N.y.)

مصطلحات موضوعية: virology [COVID-19], medicine.disease_cause, Antibodies, Viral, metabolism [Angiotensin-Converting Enzyme 2], genetics [Spike Glycoprotein, Coronavirus], Neutralization, Germline, Epitopes, genetics [Antigens, Viral], immunology [SARS-CoV-2], immunology [COVID-19], Antigens, Viral, Coronavirus, chemistry.chemical_classification, Mutation, Multidisciplinary, Microbio, genetics [SARS-CoV-2], spike protein, SARS-CoV-2, Antigenic Variation, Vaccination, Spike Glycoprotein, Coronavirus, chemistry [Antigens, Viral], ddc:500, Angiotensin-Converting Enzyme 2, Antibody, chemistry [SARS-CoV-2], Protein Binding, chemistry [Spike Glycoprotein, Coronavirus], Coronavirus disease 2019 (COVID-19), Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), ACE2 protein, human, metabolism [Antibodies, Neutralizing], Biology, Receptor binding site, Article, Antigenic drift, immunology [Antibodies, Viral], Protein Domains, Report, medicine, Humans, metabolism [Receptors, Coronavirus], Gene, Immune Evasion, Binding Sites, metabolism [Antibodies, Viral], immunology [Spike Glycoprotein, Coronavirus], SARS-CoV-2, Biochem, COVID-19, Virology, immunology [Antigens, Viral], Antibodies, Neutralizing, immunology [Antibodies, Neutralizing], metabolism [Antigens, Viral], Enzyme, chemistry, metabolism [Spike Glycoprotein, Coronavirus], biology.protein, Binding Sites, Antibody, Reports, Receptors, Coronavirus

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a44f112f84d84b18800a45c2c75d8b9Test
http://www.scopus.com/inward/record.url?scp=85112522453&partnerID=8YFLogxKTest

2

Sequence signatures of two public antibody clonotypes that bind SARS-CoV-2 receptor binding domain

المؤلفون: Nicholas C. Wu, Gilberto C. Padron, Xueyong Zhu, Kaylee Kuzelka, Jacob R. Beal, Yiquan Wang, Beth M. Stadtmueller, Xin Chen, Ian A. Wilson, Timothy J. C. Tan, Meng Yuan, Joel Rivera-Cardona, Christopher B. Brooke

المصدر: bioRxiv
article-version (status) pre
article-version (number) 1
Nature Communications, Vol 12, Iss 1, Pp 1-10 (2021)
Nature Communications

مصطلحات موضوعية: 0301 basic medicine, Models, Molecular, Science, Protein domain, General Physics and Astronomy, Somatic hypermutation, Plasma protein binding, Immunoglobulin light chain, Crystallography, X-Ray, General Biochemistry, Genetics and Molecular Biology, Antibodies, Article, 03 medical and health sciences, 0302 clinical medicine, Protein Domains, Humans, Amino Acid Sequence, Peptide sequence, Binding selectivity, X-ray crystallography, Genetics, Multidisciplinary, biology, SARS-CoV-2, COVID-19, High-Throughput Nucleotide Sequencing, General Chemistry, Antibodies, Neutralizing, Complementarity Determining Regions, 030104 developmental biology, Antibody Formation, Spike Glycoprotein, Coronavirus, biology.protein, Angiotensin-Converting Enzyme 2, Antibody, Sequence motif, 030217 neurology & neurosurgery, Protein Binding

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc5289ed4f2dd2b49ed24da6bed5e59aTest
https://pubmed.ncbi.nlm.nih.gov/33532781Test

3

Cross-Neutralization of a SARS-CoV-2 Antibody to a Functionally Conserved Site Is Mediated by Avidity

المؤلفون: Xueyong Zhu, Nicholas C. Wu, Andrew B. Ward, Hejun Liu, Rogier W. Sanders, Jonathan L. Torres, Jelle van Schooten, Sandhya Bangaru, Chang-Chun D Lee, Marit J. van Gils, Tom G. Caniels, Philip J. M. Brouwer, Meng Yuan, Ian A. Wilson

المساهمون: Graduate School, Medical Microbiology and Infection Prevention, AII - Infectious diseases, AII - Inflammatory diseases

المصدر: Immunity
bioRxiv
article-version (status) pre
article-version (number) 1
Immunity, 53(6), 1272-1280.e5. Cell Press

مصطلحات موضوعية: 0301 basic medicine, COVID-19 Vaccines, Protein Conformation, Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), viruses, Immunology, Trimer, Cross Reactions, medicine.disease_cause, Antibodies, Viral, Epitope, Neutralization, Article, 03 medical and health sciences, Immunoglobulin Fab Fragments, 0302 clinical medicine, medicine, Humans, Immunology and Allergy, Avidity, Protein Interaction Domains and Motifs, Receptor, skin and connective tissue diseases, Conserved Sequence, Coronavirus, chemistry.chemical_classification, biology, SARS-CoV-2, fungi, COVID-19, Virology, body regions, 030104 developmental biology, Infectious Diseases, chemistry, Severe acute respiratory syndrome-related coronavirus, 030220 oncology & carcinogenesis, biology.protein, Epitopes, B-Lymphocyte, Angiotensin-Converting Enzyme 2, Antibody, Glycoprotein, Crystallization, Broadly Neutralizing Antibodies, Epitope Mapping, Protein Binding

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45e3a281dce912960aa758706ac56819Test

4

A natural mutation between SARS-CoV-2 and SARS-CoV determines neutralization by a cross-reactive antibody

المؤلفون: Linghang Peng, Meng Yuan, Xueyong Zhu, Dennis R. Burton, Deli Huang, David Nemazee, Sandhya Bangaru, Chang-Chun D Lee, Hannah L. Turner, Linlin Yang, Andrew B. Ward, Ian A. Wilson, Nicholas C. Wu

المصدر: PLoS Pathogens, Vol 16, Iss 12, p e1009089 (2020)
PLoS Pathogens
bioRxiv
article-version (status) pre
article-version (number) 1

مصطلحات موضوعية: RNA viruses, Viral Diseases, Coronaviruses, Physiology, viruses, Mutant, Antibodies, Viral, Crystallography, X-Ray, Severe Acute Respiratory Syndrome, medicine.disease_cause, Biochemistry, Epitope, Neutralization, Epitopes, 0302 clinical medicine, Medical Conditions, Immune Physiology, Electron Microscopy, Biology (General), Neutralizing antibody, skin and connective tissue diseases, Pathology and laboratory medicine, Coronavirus, Data Management, 0303 health sciences, Mutation, Microscopy, Immune System Proteins, Crystallography, biology, Chemistry, Physics, virus diseases, Phylogenetic Analysis, Medical microbiology, Condensed Matter Physics, Antigenic Variation, Phylogenetics, Infectious Diseases, Severe acute respiratory syndrome-related coronavirus, Viruses, Physical Sciences, Crystal Structure, Antibody, SARS CoV 2, Pathogens, Research Article, Computer and Information Sciences, SARS coronavirus, QH301-705.5, Protein subunit, Immunology, Cross Reactions, Research and Analysis Methods, Microbiology, Article, Antibodies, 03 medical and health sciences, Virology, Genetics, medicine, Antigenic variation, Humans, Solid State Physics, Evolutionary Systematics, Antigens, Molecular Biology, 030304 developmental biology, Taxonomy, Medicine and health sciences, Evolutionary Biology, Biology and life sciences, SARS-CoV-2, Mutagenesis, fungi, Organisms, Viral pathogens, COVID-19, Proteins, Electron Cryo-Microscopy, Covid 19, RC581-607, Antibodies, Neutralizing, Microbial pathogens, body regions, biology.protein, Parasitology, Immunologic diseases. Allergy, 030217 neurology & neurosurgery

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c1ff527488800907f7f8fdf56006633Test
https://doaj.orgTest/article/7a26590600364280b6b438a6bfd964df

5

An Alternative Binding Mode of IGHV3-53 Antibodies to the SARS-CoV-2 Receptor Binding Domain

المؤلفون: Jonathan L. Torres, Hejun Liu, Xueyong Zhu, Philip J. M. Brouwer, Tom G. Caniels, Ian A. Wilson, Nicholas C. Wu, Marit J. van Gils, Andrew B. Ward, Rogier W. Sanders, Sandhya Bangaru, Chang-Chun D Lee, Meng Yuan

المساهمون: Graduate School, Medical Microbiology and Infection Prevention, AII - Infectious diseases

المصدر: Cell Reports, Vol 33, Iss 3, Pp 108274-(2020)
bioRxiv
Cell Reports
Cell reports, 33(3):108274. Cell Press

مصطلحات موضوعية: 0301 basic medicine, Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), Protein domain, Pneumonia, Viral, Virus Neutralization, Complementarity determining region, Immunoglobulin light chain, Receptor binding site, Antibodies, Viral, Crystallography, X-Ray, spike protein, General Biochemistry, Genetics and Molecular Biology, Article, 03 medical and health sciences, Betacoronavirus, 0302 clinical medicine, Protein Domains, Neutralization Tests, Humans, antibodies, Pandemics, lcsh:QH301-705.5, x-ray crystallography, Molecular interactions, biology, Chemistry, SARS-CoV-2, COVID-19, Antibodies, Neutralizing, Complementarity Determining Regions, Cell biology, 030104 developmental biology, Antibody response, lcsh:Biology (General), Spike Glycoprotein, Coronavirus, biology.protein, Immunoglobulin heavy chain, Antibody, receptor-binding domain, Coronavirus Infections, Immunoglobulin Heavy Chains, 030217 neurology & neurosurgery

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f66d871d1e0cf835ceb8d20f1978676aTest
http://www.sciencedirect.com/scienceTest/article/pii/S2211124720312638

6

A therapeutic non-self-reactive SARS-CoV-2 antibody protects from lung pathology in a COVID-19 hamster model

المؤلفون: Julius Hoffmann, Laura Stöffler, Christian Drosten, Ian A. Wilson, Stefan Hippenstiel, Niels von Wardenburg, Jakob Trimpert, Xueyong Zhu, Dietmar Schmitz, Scott van Hoof, Andreas C. Hocke, Florian Kurth, Marcel A. Müller, Lucie Y Li, Hejun Liu, Leif E. Sander, Christiana Franke, Daria Vladimirova, Chang-Chun D Lee, Anja Richter, Marie Luisa Schmidt, Kristina Dietert, Elisa Sanchez-Sendin, Jakob Kreye, Karl Skriner, Harald Prüss, Lara Maria Jeworowski, Martin Witzenrath, Marie A Homeyer, Nikolaus Osterrieder, Nicholas C. Wu, Daniel Wendisch, Victor M. Corman, Paula Charlotte Barthel, Matthias Endres, Luca D. Bertzbach, Azza Abdelgawad, Meng Yuan, Norbert Suttorp, S. Momsen Reincke, Markus Höltje, Tatjana Schwarz, Hans Christian Kornau, Achim D. Gruber

المصدر: Cell
Cell 183(4), 1058-1069.e19 (2020). doi:10.1016/j.cell.2020.09.049

مصطلحات موضوعية: virology [Pneumonia, Viral], chemistry [Peptidyl-Dipeptidase A], Ace2 protein, mouse, viruses, Antibodies, Viral, Crystallography, X-Ray, Epitope, Antigen-Antibody Reactions, Mice, crystal structures, 0302 clinical medicine, Cricetinae, Neutralizing antibody, Lung, virology [Coronavirus Infections], pathology [Lung], 0303 health sciences, drug therapy [Coronavirus Infections], biology, Antibodies, Monoclonal, neutralizing antibody, spike protein, SARS-CoV-2, Pathophysiology, medicine.anatomical_structure, Spike Glycoprotein, Coronavirus, Angiotensin-Converting Enzyme 2, Antibody, Function and Dysfunction of the Nervous System, Coronavirus Infections, pathogenicity [Betacoronavirus], post-exposure, therapeutic use [Antibodies, Monoclonal], Protein Binding, chemistry [Spike Glycoprotein, Coronavirus], medicine.drug_class, Pneumonia, Viral, Hamster, ACE2 protein, human, Molecular Dynamics Simulation, Peptidyl-Dipeptidase A, Monoclonal antibody, metabolism [Lung], General Biochemistry, Genetics and Molecular Biology, Article, immunology [Antibodies, Viral], 03 medical and health sciences, Betacoronavirus, medicine, hamster model, Animals, Humans, ddc:610, metabolism [Peptidyl-Dipeptidase A], Pandemics, self-antigens, autoreactivity, 030304 developmental biology, immunology [Lung], Binding Sites, immunology [Spike Glycoprotein, Coronavirus], SARS-CoV-2, therapeutic use [Antibodies, Viral], pathology [Pneumonia, Viral], COVID-19, drug therapy [Pneumonia, Viral], metabolism [Betacoronavirus], pathology [Coronavirus Infections], Virology, Antibodies, Neutralizing, immunology [Antibodies, Neutralizing], immunology [Betacoronavirus], Mice, Inbred C57BL, Disease Models, Animal, Kinetics, immunology [Antibodies, Monoclonal], Immunization, monoclonal antibody, metabolism [Spike Glycoprotein, Coronavirus], biology.protein, self-reactivity, 030217 neurology & neurosurgery

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5418ec544a5ad15fbfd4125ba4fd2f9dTest
http://europepmc.org/articles/PMC7510528Test

7

A Sars-Cov-2 Neutralizing Antibody Protects from Lung Pathology in a Covid-19 Hamster Model

المؤلفون: Jakob Trimpert, Florian Kurth, Marcel A. Müller, Chang-Chun D Lee, Kristina Dietert, Nicholas C. Wu, Lucie Y Li, Scott van Hoof, Daniel Wendisch, Leif E. Sander, Azza Abdelgawad, Martin Witzenrath, Marie A Homeyer, Meng Yuan, Julius Hoffmann, Achim D. Gruber, Tatjana Schwarz, Stefan Hippenstiel, Laura Stöffler, Karl Skriner, S. Momsen Reincke, Jakob Kreye, Hejun Liu, Dietmar Schmitz, Matthias Endres, Paula Charlotte Barthel, Elisa Sanchez-Sendin, Hans-Christian Kornau, Harald Prüss, Markus Höltje, Xueyong Zhu, Marie Luisa Schmidt, Andreas C. Hocke, Norbert Suttorp, Christiana Franke, Daria Vladimirova, Nikolaus Osterrieder, Ian A. Wilson, Luca D. Bertzbach, Anja Richter, Christian Drosten, Niels von Wardenburg, Lara Maria Jeworowski, Victor M. Corman

المصدر: bioRxiv
article-version (status) pre
article-version (number) 1

مصطلحات موضوعية: biology, business.industry, medicine.drug_class, viruses, Hamster, Monoclonal antibody, Virology, Article, Pathophysiology, Epitope, medicine.anatomical_structure, Immunization, medicine, biology.protein, Antibody, Function and Dysfunction of the Nervous System, business, Neutralizing antibody, IC50, B cell

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f02561afb0072fcde8e7af1b6fb4153eTest
https://doi.org/10.2139/ssrn.3680870Test

8

A multifunctional human monoclonal neutralizing antibody that targets a unique conserved epitope on influenza HA

المؤلفون: Ryan P. Irving, Robin G. Bombardi, Randy A. Albrecht, Ian A. Wilson, Sandhya Bangaru, Shanshan Lang, Heng Zhang, Hillary A. Vanderven, Pavlo Gilchuk, Iuliia M. Gilchuk, Stephen J. Kent, Travis Nieusma, Pranathi Matta, James E. Crowe, Thomas G. Voss, Xueyong Zhu, Juergen A. Richt, Andrew B. Ward

المصدر: Nature Communications, Vol 9, Iss 1, Pp 1-15 (2018)
Nature Communications

مصطلحات موضوعية: 0301 basic medicine, medicine.drug_class, Viral protein, Swine, Science, viruses, 030106 microbiology, General Physics and Astronomy, Hemagglutinin (influenza), Hemagglutinin Glycoproteins, Influenza Virus, Cross Reactions, Monoclonal antibody, medicine.disease_cause, Antibodies, Viral, General Biochemistry, Genetics and Molecular Biology, Epitope, Antigenic drift, Article, 03 medical and health sciences, Epitopes, Orthomyxoviridae Infections, Influenza, Human, medicine, Influenza A virus, Animals, Humans, Neutralizing antibody, lcsh:Science, Swine Diseases, Multidisciplinary, biology, Influenza A Virus, H3N2 Subtype, Antibody-Dependent Cell Cytotoxicity, Antibodies, Monoclonal, food and beverages, General Chemistry, Virology, Antibodies, Neutralizing, 3. Good health, 030104 developmental biology, biology.protein, lcsh:Q, Antibody

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7b25d168b923eb482e8c9e2486e0d3cTest
http://link.springer.comTest/article/10.1038/s41467-018-04704-9

9

A combination of cross-neutralizing antibodies synergizes to prevent SARS-CoV-2 and SARS-CoV pseudovirus infection

المساهمون: Medical Microbiology and Infection Prevention, AII - Infectious diseases

المصدر: bioRxiv
article-version (status) pre
article-version (number) 1
Cell host & microbe, 29(5), 806-818.e6. Cell Press
Cell host and microbe 29(5), 806-818.e6 (2021). doi:10.1016/j.chom.2021.04.005
Cell Host & Microbe

مصطلحات موضوعية: viruses, cross-neutralizing antibody, coronavirus, synergy, 3D structure, Antibodies, Viral, Severe Acute Respiratory Syndrome, medicine.disease_cause, metabolism [Angiotensin-Converting Enzyme 2], chemistry [Antibodies, Viral], immunology [SARS Virus], Neutralization, 0302 clinical medicine, Pandemic, immunology [SARS-CoV-2], prevention & control [Severe Acute Respiratory Syndrome], skin and connective tissue diseases, Coronavirus, 0303 health sciences, biology, virus diseases, immunology [Severe acute respiratory syndrome-related coronavirus], Severe acute respiratory syndrome-related coronavirus, Spike Glycoprotein, Coronavirus, Angiotensin-Converting Enzyme 2, Antibody, 2019-20 coronavirus outbreak, Coronavirus disease 2019 (COVID-19), Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), ACE2 protein, human, prevention & control [COVID-19], Cross Reactions, Microbiology, Article, Antigenic drift, immunology [Antibodies, Viral], antibody cocktail, chemistry [Antibodies, Neutralizing], 03 medical and health sciences, ddc:570, Virology, medicine, Antigenic variation, Humans, crystallography, 030304 developmental biology, SARS-CoV-2, fungi, COVID-19, Antibodies, Neutralizing, immunology [Antibodies, Neutralizing], body regions, metabolism [Spike Glycoprotein, Coronavirus], antibody-antigen interaction, biology.protein, Parasitology, 030217 neurology & neurosurgery

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::adf08c7509dedd958cc92d18c46463d3Test
https://doi.org/10.1016/j.chom.2021.04.005Test

10

Genetically encoding phosphotyrosine and its nonhydrolyzable analog in bacteria

المؤلفون: Yuhan Zhang, Feng Wang, Anzhi Yao, Xiaoxuan Lyu, Sean A. Reed, Xiaozhou Luo, Peng-Yu Yang, Chunhui Huang, Xueyong Zhu, Renhe Liu, Peter G. Schultz, Rongsheng E. Wang, Weimin Xuan, Ian A. Wilson, Mingchao Kang, Claudio Zambaldo, Tao Liu, Guangsen Fu, Hui Guo, Jintang Du

المصدر: Nature chemical biology

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94dc84c54ebf75d6a7e032304bb4e894Test
http://europepmc.org/articles/PMC5577365Test

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