المؤلفون: Cross, W., Kovac, M., Mustonen, V., Temko, D., Davis, H., Baker, A.-M., Biswas, S., Arnold, R., Chegwidden, L., Gatenbee, C., Anderson, A.R., Koelzer, V.H., Martinez, P., Jiang, X., Domingo, E., Woodcock, D.J., Feng, Y., Kovacova, M., Maughan, T., Adams, R., Bach, S., Beggs, A., Brown, L., Buffa, F., Cazier, J.-B., Blake, A., Wu, C.-H., Chatzpili, E., Richman, S., Dunne, P., Harkin, P., Higgins, G., Hill, J., Holmes, C., Horgan, D., Kaplan, R., Kennedy, R., Lawler, M., Leedham, S., McDermott, U., McKenna, G., Middleton, G., Morton, D., Murray, G., Quirke, P., Salto-Tellez, M., Samuel, L., Schuh, A., Sebag-Montefiore, D., Seymour, M., Sharma, R., Sullivan, R., Tomlinson, I., West, N., Wilson, R., Jansen, M., Rodriguez-Justo, M., Ashraf, S., Guy, R., Cunningham, C., East, J.E., Wedge, D.C., Wang, L.M., Palles, C., Heinimann, K., Sottoriva, A., Graham, T.A., Tomlinson, I.P.M.

المصدر: Cross, W, Kovac, M, Mustonen, V, Temko, D, Davis, H, Baker, A-M, Biswas, S, Arnold, R, Chegwidden, L, Gatenbee, C, Anderson, A R, Koelzer, V H, Martinez, P, Jiang, X, Domingo, E, Woodcock, D J, Feng, Y, Kovacova, M, Maughan, T, Adams, R, Bach, S, Beggs, A, Brown, L, Buffa, F, Cazier, J-B, Domingo, E, Blake, A, Wu, C-H, Chatzpili, E, Richman, S, Dunne, P, Harkin, P, Higgins, G, Hill, J, Holmes, C, Horgan, D, Kaplan, R, Kennedy, R, Lawler, M, Leedham, S, Maughan, T, McDermott, U, McKenna, G, Middleton, G, Morton, D, Murray, G, Quirke, P, Salto-Tellez, M, Samuel, L, Schuh, A, Sebag-Montefiore, D, Seymour, M, Sharma, R, Sullivan, R, Tomlinson, I, West, N, Wilson, R, Jansen, M, Rodriguez-Justo, M, Ashraf, S, Guy, R, Cunningham, C, East, J E, Wedge, D C, Wang, L M, Palles, C, Heinimann, K, Sottoriva, A, Leedham, S, Graham, T A & Tomlinson, I P M 2018, ' The evolutionary landscape of colorectal tumorigenesis ', Nature Ecology and Evolution . https://doi.org/10.1038/s41559-018-0642-zTest
Nature ecology & evolution

مصطلحات موضوعية: 0301 basic medicine, Adenoma, Fitness landscape, Carcinogenesis, Evolutionary landscape, Biology, medicine.disease_cause, Models, Biological, Article, Evolution, Molecular, 03 medical and health sciences, medicine, Humans, Stabilizing selection, Ecology, Evolution, Behavior and Systematics, Exome sequencing, Ecology, Manchester Cancer Research Centre, Genetic heterogeneity, ResearchInstitutes_Networks_Beacons/mcrc, Carcinoma, Cancer, medicine.disease, 030104 developmental biology, Evolutionary biology, Mutation, Colorectal Neoplasms

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3ca8e66b8acd7d108cf45e67d5a470dTest
http://eprints.whiterose.ac.uk/139375Test/

المؤلفون: Cazier, J.-B., Rao, S.R., McLean, C.M., Walker, A.L., Wright, B.J., Jaeger, E.E.M., Kartsonaki, C., Marsden, L., Yau, C., Camps, C., Kaisaki, P., Taylor, J., Catto, J.W., Tomlinson, I.P.M., Kiltie, A.E., Hamdy, F.C.

المصدر: Nature Communications

مصطلحات موضوعية: Cyclin-Dependent Kinase Inhibitor p21, Genome, Base Sequence, Urinary Bladder Neoplasms, Molecular Sequence Data, Mutation, Genetic Variation, Humans, Sequence Analysis, DNA, Neoplasm Grading, Cadherins, Article

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=pmid________::985f474858323a73b1c19ae7bfc5050cTest
http://europepmc.org/articles/PMC4010643Test