المؤلفون: Jake Siu-Lun Leung, Kwok-Yung Yuen, Honglian Liu, Rachel Chun Yee Tam, Kwok-Hung Chan, Siwen Liu, Bobo Wing-Yee Mok, Pui Wang, Honglin Chen, Gilman Kit Hang Siu, Conor J. Cremin, Kelvin K. W. To, Jiayan Liu, Jasper Fuk-Woo Chan, Shaofeng Deng, Siu-Ying Lau, Timothy Ting-Leung Ng, Anna Jinxia Zhang, Lam-Kwong Lee

المصدر: Communications Biology, Vol 4, Iss 1, Pp 1-8 (2021)
Communications Biology

مصطلحات موضوعية: QH301-705.5, Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), Medicine (miscellaneous), Hamster, Alpha (ethology), Viral transmission, Biology, Virus Replication, Article, General Biochemistry, Genetics and Molecular Biology, Cell Line, law.invention, law, Cricetinae, Animals, Humans, Biology (General), Competitive fitness, SARS-CoV-2, Low dose, COVID-19, Virology, Disease Models, Animal, Key factors, Transmission (mechanics), Viral replication, General Agricultural and Biological Sciences

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0a24d7a0e1cd66aab346c80d73a3995Test
https://doi.org/10.1038/s42003-021-02640-xTest

المؤلفون: Yan Zhao, Kelvin K. W. To, Kwok-Yung Yuen, Fei-Fei Liu, Andrew Chak-Yiu Lee, Siu-Ying Lau, Honglin Chen, Hin Chu, Anna Jinxia Zhang, Yanxia Chen, Carol Ho-Yan Fong, Pui Wang, Can Li

المصدر: npj Vaccines, Vol 6, Iss 1, Pp 1-13 (2021)
NPJ Vaccines

مصطلحات موضوعية: Pharmacology, Vaccines, Live attenuated vaccines, business.industry, Immunogenicity, Immunology, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC581-607, Article, Virus, Proinflammatory cytokine, Vaccination, Infectious Diseases, Immunization, Medicine, Live attenuated influenza vaccine, Pharmacology (medical), Nasal administration, Intradermal injection, Immunologic diseases. Allergy, Influenza virus, business, RC254-282

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac7fd451b884977d6f009b985f938e12Test
https://doi.org/10.1038/s41541-021-00359-8Test

المؤلفون: Runhong Zhou, Pui Wang, Yik-Chun Wong, Haoran Xu, Siu-Ying Lau, Li Liu, Bobo Wing-Yee Mok, Qiaoli Peng, Na Liu, Kin-Fai Woo, Shaofeng Deng, Rachel Chun-Yee Tam, Haode Huang, Anna Jinxia Zhang, Dongyan Zhou, Biao Zhou, Chun-Yin Chan, Zhenglong Du, Dawei Yang, Ka-Kit Au, Kwok-Yung Yuen, Honglin Chen, Zhiwei Chen

المصدر: EBioMedicine, Vol 75, Iss, Pp 103762-(2022)
EBioMedicine

مصطلحات موضوعية: Male, Medicine (General), COVID-19 Vaccines, Immunization, Secondary, Mice, Transgenic, Live-attenuated influenza-based vaccine, Vaccines, Attenuated, General Biochemistry, Genetics and Molecular Biology, Article, Madin Darby Canine Kidney Cells, Mice, R5-920, Dogs, Mucosal immunity, Chlorocebus aethiops, Vaccines, DNA, Animals, Humans, Immunity, Mucosal, Vero Cells, Administration, Intranasal, Mice, Inbred BALB C, SARS-CoV-2, Nasal prevention, COVID-19, General Medicine, Disease Models, Animal, HEK293 Cells, Influenza Vaccines, PD1-based DNA vaccine, Medicine, Female, Receptor binding domain

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b48bb677d6e0aea724b90e7de057aee8Test
https://pubmed.ncbi.nlm.nih.gov/34942445Test

المؤلفون: Jessie D. Trujillo, Emily R. Miraldi, Jan Bakker, Benjamin R. tenOever, Andre L. Moreira, Helen Ray-Jones, Ivan Marazzi, Simin Zheng, Nan Zhao, Laura Campisi, Michael Schotsaert, Zeyu Zhu, Sven Heinz, Elaine Shum, Christopher Benner, Jessica Sook Yuin Ho, Anna Junxia Zhang, Adolfo García-Sastre, Sreeja Parameswaran, Joseph A. Wayman, Matthew T. Weirauch, Anand D. Jeyasekharan, Yesai Fstkchyan, Igor Morozov, Wen-Chun Liu, Minji Byun, Sumit K. Chanda, Sabarish V. Indran, Natasha N. Gaudreault, Mikhail Spivakov, Honglin Chen, Alba Escalera, Bobo Wing-Yee Mok, Kris M. White, Juergen A. Richt, Mariano Carossino, Valeriya Malysheva, Randy A. Albrecht, Tristan X. Jordan, Teresa Aydillo, Robert Sebra, Betsaida Salom Melo, Andrew Chak-Yiu Lee, Sonia Jangra, Udeni B. R. Balasuriya, David A. Meekins, Ernesto Guccione, Siu Ying Lau, Soner Yildiz, Michiel J. Thiecke, David A. Kaufman, Raveen Rathnasinghe, Honglian Liu

المساهمون: Intensive Care

المصدر: Cell, 184(10), 2618-2632.e17. Cell Press
Cell, vol 184, iss 10
Cell

مصطلحات موضوعية: THP-1 Cells, Type I, Pharmacology, Medical and Health Sciences, Transgenic, Mice, 0302 clinical medicine, inducible genes, Chlorocebus aethiops, Lung, topoisomerase, 0303 health sciences, Biological Sciences, Infectious Diseases, 5.1 Pharmaceuticals, cytokine storm, Pneumonia & Influenza, Development of treatments and therapeutic interventions, medicine.symptom, transcription, medicine.drug, Genetically modified mouse, Inflammation, Biology, Topoisomerase-I Inhibitor, Article, General Biochemistry, Genetics and Molecular Biology, Proinflammatory cytokine, Vaccine Related, 03 medical and health sciences, Pharmacotherapy, topotecan, Biodefense, medicine, Animals, Humans, Vero Cells, 030304 developmental biology, Mesocricetus, epigenetics, SARS-CoV-2, Prevention, Inflammatory and immune system, Topoisomerase, COVID-19, Pneumonia, medicine.disease, COVID-19 Drug Treatment, Emerging Infectious Diseases, Good Health and Well Being, inflammation, biology.protein, chromatin, Topotecan, Topoisomerase I Inhibitors, Cytokine storm, 030217 neurology & neurosurgery, DNA Topoisomerases, Developmental Biology

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d169781a64bf58af62230f5b19d8e6adTest
https://pure.eur.nl/en/publications/c6a3d84a-3a2d-4ff6-9904-1d7f6b018446Test

المؤلفون: Jessica Sook Yuin Ho, Bobo Wing-Yee Mok, Laura Campisi, Tristan Jordan, Soner Yildiz, Sreeja Parameswaran, Joseph A Wayman, Natasha N Gaudreault, David A Meekins, Sabarish V. Indran, Igor Morozov, Jessie D Trujillo, Yesai S Fstkchyan, Raveen Rathnasinghe, Zeyu Zhu, Simin Zheng, Nan Zhao, Kris White, Helen Ray-Jones, Valeriya Malysheva, Michiel J Thiecke, Siu-Ying Lau, Honglian Liu, Anna Junxia Zhang, Andrew Chak-Yiu Lee, Wen-Chun Liu, Teresa Aydillo, Betsaida Salom Melo, Ernesto Guccione, Robert Sebra, Elaine Shum, Jan Bakker, David A. Kaufman, Andre L. Moreira, Mariano Carossino, Udeni B R Balasuriya, Minji Byun, Emily R Miraldi, Randy A Albrecht, Michael Schotsaert, Adolfo Garcia-Sastre, Sumit K Chanda, Anand D Jeyasekharan, Benjamin R TenOever, Mikhail Spivakov, Matthew T Weirauch, Sven Heinz, Honglin Chen, Christopher Benner, Juergen A Richt, Ivan Marazzi

المصدر: bioRxiv

مصطلحات موضوعية: Genetically modified mouse, THP-1 Cells, Inflammation, Mice, Transgenic, Pharmacology, Article, Proinflammatory cytokine, Mice, In vivo, Chlorocebus aethiops, medicine, Animals, Humans, Epigenetics, Vero Cells, biology, Mesocricetus, business.industry, SARS-CoV-2, Topoisomerase, COVID-19, In vitro, COVID-19 Drug Treatment, DNA Topoisomerases, Type I, biology.protein, Topotecan, medicine.symptom, Topoisomerase I Inhibitors, business, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0569b26060aba6559d1d01d0d172051Test
https://pubmed.ncbi.nlm.nih.gov/33836156Test

المؤلفون: Honglian Liu, Xiaofeng Huang, Bobo Wing-Yee Mok, Yixin Chen, Wenjun Song, Min Zheng, Pin Chen, Siu-Ying Lau, Honglin Chen, Pui Wang, Yen-Chin Liu, Kwok-Yung Yuen, Siwen Liu

المصدر: Nature Communications, Vol 8, Iss 1, Pp 1-15 (2017)
Nature Communications

مصطلحات موضوعية: 0301 basic medicine, Gene Expression Regulation, Viral, animal structures, RNA Splicing, viruses, Science, Exonic splicing enhancer, General Physics and Astronomy, Biology, Viral Nonstructural Proteins, medicine.disease_cause, Influenza A Virus, H7N9 Subtype, Virus Replication, General Biochemistry, Genetics and Molecular Biology, Virus, Article, 03 medical and health sciences, Exon, Influenza, Human, Influenza A virus, medicine, Influenza A Virus, H9N2 Subtype, Humans, RNA, Messenger, Genetics, Messenger RNA, Multidisciplinary, HEK 293 cells, fungi, virus diseases, General Chemistry, Exons, 030104 developmental biology, Enhancer Elements, Genetic, HEK293 Cells, Viral replication, A549 Cells, RNA splicing, RNA, Viral

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bce1339915de215274fd46638cb93d90Test
https://doaj.orgTest/article/2633172c87034f53bb00b4b09dbedbec

المؤلفون: Kwok-Yung Yuen, Ivan Hung, Honglin Chen, Wenjun Song, Kelvin K. W. To, Tak-Lun Que, Siu-Ying Lau, David Christopher Lung

المصدر: The Journal of Infection

مصطلحات موضوعية: Adult, Microbiology (medical), Evolution, Molecular Sequence Data, Sequence Homology, Avian influenza, Disease, Biology, Influenza A Virus, H7N9 Subtype, medicine.disease_cause, Communicable Diseases, Emerging, H5N1 genetic structure, Article, Virus, Evolution, Molecular, H7N9, Viral Proteins, Influenza, Human, medicine, Cluster Analysis, Humans, Phylogeny, Cytopenia, Mutation, Sequence Analysis, DNA, RNA-Dependent RNA Polymerase, medicine.disease, Virology, Influenza A virus subtype H5N1, L336M, Trachea, Infectious Diseases, Viral replication, Hong Kong, RNA, Viral, Female, Liver function, Reassortant Viruses, Phylogenetic tree, PA

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b0cf77380a59c19aebef0e10419d5a2Test
https://doi.org/10.1016/j.jinf.2014.02.012Test

المؤلفون: Wenjun Song, Siu-Ying Lau, Bobo Wing-Yee Mok, Honglian Liu, Xiaofeng Huang, Conor J. Cremin, Honglin Chen, Pui Wang, Min Zheng, Pin Chen, Siwen Liu

المصدر: Viruses
Volume 11
Issue 3
Viruses, Vol 11, Iss 3, p 292 (2019)

مصطلحات موضوعية: 0301 basic medicine, animal diseases, viruses, 030106 microbiology, lcsh:QR1-502, Mutation, Missense, Cross-species transmission, Biology, Virus Replication, medicine.disease_cause, lcsh:Microbiology, Article, Virus, RNP, Birds, Mice, Viral Proteins, 03 medical and health sciences, Virology, Influenza, Human, medicine, Animals, Humans, Clade, Mice, Inbred BALB C, Mutation, cross species transmission, Influenza A Virus, H5N1 Subtype, Host (biology), virus diseases, H5N1, host adaptation, Adaptation, Physiological, humanities, Influenza A virus subtype H5N1, 030104 developmental biology, Infectious Diseases, Amino Acid Substitution, PB2, Indonesia, Influenza in Birds, Host-Pathogen Interactions, Egypt, Host adaptation, Adaptation, Influenza virus

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0b179542abd7b4b375ea92503562993Test
https://doi.org/10.3390/v11030292Test

المؤلفون: Xing Yao, Lanjuan Li, Hainv Gao, Shichang Xia, Shigui Yang, Jifang Sheng, Yanjun Zhang, Dawei Cui, Jade Lee-Lee Teng, Yu Chen, Yun-Tao Zhang, Qiang Fang, Nanping Wu, Haibo Wu, Jasper Fuk-Woo Chan, Hongyan Diao, Honglin Chen, Pui Wang, Kwok-Hung Chan, Hangping Yao, Min Zheng, Kwok-Yung Yuen, Yongcheng Li, Shufa Zheng, Wenjun Song, Kelvin K. W. To, Weifeng Liang, Siu-Ying Lau, Jianer Wo, Hoi-Wah Tsoi

المصدر: Lancet (London, England)

مصطلحات موضوعية: Male, China, medicine.drug_class, viruses, Antibiotics, Genome, Viral, Biology, medicine.disease_cause, Communicable Diseases, Emerging, Poultry, Article, Virus, Zoonoses, Influenza, Human, medicine, Animals, Humans, Transmission (medicine), General Medicine, Middle Aged, medicine.disease, Virology, Influenza A virus subtype H5N1, Influenza A virus, Influenza in Birds, Viral evolution, Sputum, Female, Human Virus, medicine.symptom, Tomography, X-Ray Computed, Pneumonia (non-human)

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ee40bd87f8ba5998cb44644994a4fc7Test
https://doi.org/10.1016/s0140-6736Test(13)60903-4

المؤلفون: Honglin Chen, Pui Wang, Wai Lan Wu, Wenjun Song, Tianwei Lin, Bobo Wing-Yee Mok, Xi Wen, Kwok-Yung Yuen, Genyan Wang, Yixin Chen, Kwok-Hung Chan, Siu-Ying Lau

المصدر: Antiviral Research. 93:144-153

مصطلحات موضوعية: viruses, Resistance, Mice, chemistry.chemical_compound, Mice, Inbred BALB/c, Influenza A Virus, H1N1 Subtype, H275Y, Phylogeny, Mice, Inbred BALB C, biology, Immunogenicity, H1N1, Antibody titer, Drug resistance, Viral - genetics, Antibodies, Monoclonal, virus diseases, Middle Aged, Female, Viral proteins - genetics - immunology - metabolism, Antibody, Adult, Oseltamivir, Genotype, Influenza A virus, H1N1 subtype - drug effects - genetics - immunology, Neuraminidase, Antiviral Agents, Article, Virus, Cell Line, Microbiology, Viral Proteins, Young Adult, Orthomyxoviridae Infections, Antigen, Oseltamivir - pharmacology, Orthomyxoviridae infections - immunology, Virology, Drug Resistance, Viral, Animals, Humans, Pharmacology, Hemagglutination assay, Influenza, Antibodies, Monoclonal - immunology, respiratory tract diseases, Neuraminidase - genetics - immunology - metabolism, Amino Acid Substitution, chemistry, Mutation, biology.protein, Antiviral agents - pharmacology

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86179addf55142e4c3490470efd56ea3Test
https://doi.org/10.1016/j.antiviral.2011.11.006Test