المؤلفون: Geetika Singh, Cristina D. Guibao, Jayaraman Seetharaman, Anup Aggarwal, Christy R. Grace, Dan E. McNamara, Sivaraja Vaithiyalingam, M. Brett Waddell, Tudor Moldoveanu

المصدر: Nature Communications, Vol 13, Iss 1, Pp 1-15 (2022)
Nature Communications

مصطلحات موضوعية: Multidisciplinary, Cell Death, Science, General Physics and Astronomy, Membrane Proteins, Apoptosis, General Chemistry, Crystallography, X-Ray, Ligands, General Biochemistry, Genetics and Molecular Biology, Article, Mitochondria, bcl-2 Homologous Antagonist-Killer Protein, Proto-Oncogene Proteins c-bcl-2, Liposomes, Humans, biological phenomena, cell phenomena, and immunity, BH3 Interacting Domain Death Agonist Protein, X-ray crystallography

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb8385f4f44c0480b152b55aa3c2761dTest
https://doaj.orgTest/article/948c7729db444ae0965cb207d8ea6853

المؤلفون: Barbara Jonchere, Jonathan Low, Michele Connelly, Liying Chi, Sergio C. Chai, R. Kiplin Guy, Kevin W. Freeman, Brandon Young, Jeanine E. Price, Mi-Kyung Yun, Marie Morfouace, Anang A. Shelat, Geoffrey Neale, Rachelle R. Olsen, Nagakumar Bharatham, Daniel Savic, Stephen W. White, P. Jake Slavish, Vincent A. Boyd, Lyudmila Tsurkan, Jun J. Yang, Nancy E. Martinez, Zhenmei Li, Martine F. Roussel, Philip M. Potter, M. Brett Waddell, William R. Shadrick, Richard E. Lee, Taosheng Chen, Sourav Das

المصدر: Cancer Res

مصطلحات موضوعية: 0301 basic medicine, Cancer Research, Antineoplastic Agents, Context (language use), Mice, SCID, Article, Proto-Oncogene Proteins c-myc, Mice, Structure-Activity Relationship, 03 medical and health sciences, 0302 clinical medicine, Protein Domains, Cell Line, Tumor, Neoplasms, Neuroblastoma, medicine, Animals, Humans, Child, Cytotoxicity, Oncogene, Chemistry, Cancer, medicine.disease, Xenograft Model Antitumor Assays, Pediatric cancer, Bromodomain, 030104 developmental biology, Oncology, Drug development, Drug Design, 030220 oncology & carcinogenesis, Cancer research, Female, Transcription Factors

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86d687ae06b408a0a8a364651477a03fTest
https://doi.org/10.1158/0008-5472.can-19-3934Test

المؤلفون: Mi-Kyung Yun, Maksym Tsytlonok, Peter Tompa, Sivaraja Vaithiyalingam, Suren Felekyan, Claus A. M. Seidel, Aaron H. Phillips, Luigi I. Iconaru, Yuefeng Wang, Hugo Sanabria, Stephen W. White, M. Brett Waddell, Richard W. Kriwacki, Katherina Hemmen, Cheon-Gil Park

المصدر: Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
Nature Communications

مصطلحات موضوعية: Threonine, 0301 basic medicine, Quantitative Biology - Subcellular Processes, Cell division, Cyclin A, Fusion Proteins, bcr-abl, General Physics and Astronomy, 02 engineering and technology, Crystallography, X-Ray, Quantitative Biology - Quantitative Methods, chemistry.chemical_compound, Phosphorylation, lcsh:Science, Quantitative Methods (q-bio.QM), Multidisciplinary, biology, Chemistry, 021001 nanoscience & nanotechnology, Recombinant Proteins, Cell biology, src-Family Kinases, 0210 nano-technology, Tyrosine kinase, Cell Division, Cyclin-Dependent Kinase Inhibitor p27, Protein Binding, Signal Transduction, Proto-oncogene tyrosine-protein kinase Src, Science, Molecular Dynamics Simulation, Article, General Biochemistry, Genetics and Molecular Biology, 03 medical and health sciences, Cyclin-dependent kinase, Subcellular Processes (q-bio.SC), Cyclin-Dependent Kinase 2, Cyclin-dependent kinase 2, Tyrosine phosphorylation, Biomolecules (q-bio.BM), General Chemistry, Protein Structure, Tertiary, 030104 developmental biology, Quantitative Biology - Biomolecules, FOS: Biological sciences, Proteolysis, Mutagenesis, Site-Directed, biology.protein, Tyrosine, lcsh:Q, Protein Processing, Post-Translational

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aebf5b582a25ff50bd576925e3ed1b6aTest
http://arxiv.org/abs/1812.07009Test

المؤلفون: Richard E. Lee, Stephen W. White, Zhenmei Li, M. Brett Waddell, Ying Zhao, Donald Bashford, Antonio M. Ferreira, Yinan Wu, Mi Kyung Yun

المصدر: Science. 335:1110-1114

مصطلحات موضوعية: Models, Molecular, Sulfamethoxazole, Protein Conformation, Yersinia pestis, Stereochemistry, Molecular Sequence Data, Parabens, DHPS, Biology, Crystallography, X-Ray, Article, chemistry.chemical_compound, Sulfathiazole, Protein structure, Catalytic Domain, parasitic diseases, Drug Resistance, Bacterial, 4-Aminobenzoic acid, Transferase, Magnesium, Amino Acid Sequence, Pterin, Sulfathiazoles, chemistry.chemical_classification, Dihydropteroate Synthase, Multidisciplinary, Mutagenesis, Anti-Bacterial Agents, Sulfonamide, Diphosphates, Models, Chemical, Biochemistry, chemistry, Bacillus anthracis, Biocatalysis, Crystallization, Dihydropteroate synthase, 4-Aminobenzoic Acid

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::972532e2c1adb13ccd74474a72d311baTest
https://doi.org/10.1126/science.1214641Test

المؤلفون: Steven N. Seyedin, Timothy Hoggard, Jiang Liu, Amanda Nourse, Min Zhuang, Michal Hammel, David M. Duda, Kevin P. White, J. Wade Harper, Helen Walden, Matthew F. Calabrese, Darcie J. Miller, Brenda A. Schulman, M. Brett Waddell

المصدر: Molecular Cell. 36(1):39-50

مصطلحات موضوعية: Models, Molecular, Co-Repressor Proteins, Recombinant Fusion Proteins, Ubiquitin-Protein Ligases, Computational biology, SPOP, Crystallography, X-Ray, Article, Histones, Protein structure, Consensus Sequence, Phosphoprotein Phosphatases, Animals, Drosophila Proteins, Humans, Protein Interaction Domains and Motifs, Amino Acid Sequence, Protein Structure, Quaternary, Molecular Biology, Adaptor Proteins, Signal Transducing, biology, Cullin Proteins, Ubiquitination, Nuclear Proteins, Cell Biology, Peptide Fragments, Chromatin, Ubiquitin ligase, DNA-Binding Proteins, Repressor Proteins, Drosophila melanogaster, Biochemistry, Mutation, biology.protein, Protein Multimerization, Cullin, Molecular Chaperones, Protein Binding, Transcription Factors

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba3c3d9cbf9cfaab45e912fafb9471e2Test

المؤلفون: Daniel Hoagland, M. Brett Waddell, Richard E. Lee, Mi-Kyung Yun, Charles O. Rock, Gyanendra Kumar, Stephen W. White

المصدر: Bioorganicmedicinal chemistry. 22(7)

مصطلحات موضوعية: Models, Molecular, Stereochemistry, Clinical Biochemistry, Pharmaceutical Science, Crystallography, X-Ray, Biochemistry, Article, chemistry.chemical_compound, Structure-Activity Relationship, Drug Discovery, Structure–activity relationship, Hydroxymethyl, Pterin, Enzyme Inhibitors, Thioguanine, Molecular Biology, chemistry.chemical_classification, Dose-Response Relationship, Drug, Molecular Structure, Organic Chemistry, Antimicrobial, Enzyme, chemistry, Diphosphotransferases, Molecular Medicine, Structure based

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90f9921bdc40b87ae834f986df41d1ceTest
https://pubmed.ncbi.nlm.nih.gov/24613625Test

المؤلفون: M. Brett Waddell, Richard W. Kriwacki, Li Ou

المصدر: ACS chemical biology. 7(4)

مصطلحات موضوعية: Cyclin-dependent kinase 1, biology, Cyclin D, Cyclin A, Cell Cycle, Cyclin-Dependent Kinase 4, General Medicine, Cell Cycle Checkpoints, Cell cycle, Biochemistry, Cyclin-Dependent Kinases, Article, Cell biology, Cyclin-dependent kinase, Cyclins, biology.protein, Cyclin-dependent kinase complex, Molecular Medicine, Animals, Humans, Protein phosphorylation, Phosphorylation, Cyclin A2, Cyclin-Dependent Kinase Inhibitor p27

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3cb241f71b4facc2cd3f6723af9ab755Test
https://pubmed.ncbi.nlm.nih.gov/22276948Test

المؤلفون: David M. Duda, Laura A. Borg, Mary-Ann Bjornsti, M. Brett Waddell, Brenda A. Schulman, Robert C.A.M. van Waardenburg, Amanda Nourse, Sierra McGarity

مصطلحات موضوعية: Saccharomyces cerevisiae Proteins, Molecular Sequence Data, Molecular Conformation, SUMO binding, SUMO enzymes, Plasma protein binding, Saccharomyces cerevisiae, Biology, Ubiquitin-conjugating enzyme, Crystallography, X-Ray, Article, Ubiquitin, Structural Biology, Small Ubiquitin-Related Modifier Proteins, Catalytic Domain, Humans, Amino Acid Sequence, Cysteine, Binding site, Cloning, Molecular, Molecular Biology, Sequence Homology, Amino Acid, Effector, Proteins, Cell biology, Repressor Proteins, Biochemistry, Ubiquitin-Conjugating Enzymes, biology.protein, Protein Binding

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0130a7febb824b9e831dbd4b9b8596dTest
https://europepmc.org/articles/PMC1936411Test/