المؤلفون: Sam O’Toole, Peyman Björklund, Samuel Backman, Per Hellman, Eva Wozniak, Sumedha Garg, Morris J. Brown, Emily Goodchild, Junhua Zhou, Alison Marker, Antoinette Tuthill, Giulia Argentesi, Caroline Joyce, Xilin Wu, Sheerazed Boulkroun, Celso E Gomez Sanchez, Russell Senanayake, Satyamaanasa Polubothu, Kate E Lines, Lou Metherell, Suzanne Jordan, Jyn Ling Kuan, Zenia Tiang, Laila Parvanta, Fiona E. Karet Frankl, Veronica A Kinsler, Rajesh V. Thakker, Elena A.B. Azizan, Fabio L. Fernandes-Rosa, Maria-Christina Zennaro, David Klinzing, Laurence Amar, Emily Cottrell, William Drake, Helen L Storr, Ada E. D. Teo, Juan Pablo Kaski, Roger Foo, Charles A. Mein, Tobias Åkerström, Daniel M. Berney, Claudia P. Cabrera, Anna K Gluck, Mark Gurnell

المساهمون: Queen Mary University of London (QMUL), National University of Malaysia [Bandar Baru Bangi] (UKM), Paris-Centre de Recherche Cardiovasculaire (PARCC (UMR_S 970/ U970)), Hôpital Européen Georges Pompidou [APHP] (HEGP), Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôpitaux Universitaires Paris Ouest - Hôpitaux Universitaires Île de France Ouest (HUPO)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôpitaux Universitaires Paris Ouest - Hôpitaux Universitaires Île de France Ouest (HUPO)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris Cité (UPCité), Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôpitaux Universitaires Paris Ouest - Hôpitaux Universitaires Île de France Ouest (HUPO), Addenbrooke's Hospital, Cambridge University NHS Trust, Metabolic Research Laboratories [Cambridge, UK] (University of Cambridge), Wellcome Trust - MRC Cambridge-Addenbrooke’s Hospital [Cambridge, UK], Uppsala University, Royal Free Hospital [London, UK], University College of London [London] (UCL), University of Oxford, Cork University Hospital [Cork, Ireland] (CUH), University of Cambridge [UK] (CAM), National University of Singapore (NUS), St Bartholomew's Hospital (London), Agency for science, technology and research [Singapore] (A*STAR), University of Mississippi Medical Center (UMMC), Fernandes Rosa, Fabio

المصدر: Nat Genet
Nature Genetics
Nature Genetics, 2021, 53 (9), pp.1360-1372. ⟨10.1038/s41588-021-00906-y⟩

مصطلحات موضوعية: Adult, Male, endocrine system, medicine.medical_specialty, Adolescent, education, [SDV.GEN] Life Sciences [q-bio]/Genetics, Biology, medicine.disease_cause, Article, Human chorionic gonadotropin, chemistry.chemical_compound, [SDV.MHEP.CSC]Life Sciences [q-bio]/Human health and pathology/Cardiology and cardiovascular system, Pregnancy, Internal medicine, Hyperaldosteronism, Genetics, medicine, Humans, Aldosterone, beta Catenin, [SDV.MHEP.EM] Life Sciences [q-bio]/Human health and pathology/Endocrinology and metabolism, [SDV.GEN]Life Sciences [q-bio]/Genetics, Mutation, GNA11, Adrenal gland, Adrenal cortex, Puberty, [SDV.MHEP.EM]Life Sciences [q-bio]/Human health and pathology/Endocrinology and metabolism, Middle Aged, Adrenal Cortex Neoplasms, GTP-Binding Protein alpha Subunits, [SDV.MHEP.CSC] Life Sciences [q-bio]/Human health and pathology/Cardiology and cardiovascular system, medicine.anatomical_structure, Endocrinology, chemistry, Zona glomerulosa, Adrenocortical Adenoma, GTP-Binding Protein alpha Subunits, Gq-G11, Female, Menopause, GNAQ

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f4b06af371bc122514ed8222140e35aTest
https://doi.org/10.1038/s41588-021-00906-yTest

المؤلفون: Julien Schmidt, Lluis Fajas, Eric Renard, Gökhan S. Hotamisligil, Dominique Langin, Gwendal Lazennec, Anna Gumà, Irena Iankova, Hiroyasu Yamamoto, Rosario Sanches, Antonio Vidal-Puig, Carine Chavey, Jacques Teyssier, Robert M. Strieter, Bénédicte Jardin-Watelet, Sylviane Lagarrigue, Jean-Sébastien Annicotte, Antoinette Tuthill, Michaela Vitkova, Chikage Mataki, Cyrielle Clapé, Vladimir Stich, Antonio Zorzano

المساهمون: Institut de recherche en cancérologie de Montpellier (IRCM - U896 Inserm - UM1), Université Montpellier 1 (UM1)-CRLCC Val d'Aurelle - Paul Lamarque-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Montpellier (UM), Métabolisme et cancer, Université Montpellier 1 (UM1)-Institut National de la Santé et de la Recherche Médicale (INSERM), Cellules souches mésenchymateuses, environnement articulaire et immunothérapies de la polyarthrite rhumatoide, Université Montpellier 1 (UM1)-IFR3, Institut de Génétique et de Biologie Moléculaire et Cellulaire (IGBMC), Université de Strasbourg (UNISTRA)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Institute for Research in Biomedecine, and Departement de Bioquimina Biologia Molecular, Universitat de Barcelona (UB), Department of Sport Medicine and Obesity Unit, Charles University [Prague] (CU), CNRS/Bio-Rad, Centre National de la Recherche Scientifique (CNRS), Hôpital Arnaud de Villeneuve [CHRU Montpellier], Centre Hospitalier Régional Universitaire [Montpellier] (CHRU Montpellier), Centre de pharmacologie et innovation dans le diabète (CPID), Centre National de la Recherche Scientifique (CNRS)-Centre Hospitalier Régional Universitaire [Montpellier] (CHRU Montpellier)-Université Montpellier 1 (UM1), Department of Medecine, University of Virginia [Charlottesville], Metabolic Research Laboratories, University of Cambridge [UK] (CAM), Harvard School of Public Health, Institut de médecine moléculaire de Rangueil (I2MR), Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-IFR150-Institut National de la Santé et de la Recherche Médicale (INSERM), Laboratoire de Biochimie [Purpan], Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-CHU Toulouse [Toulouse]-Institut Fédératif de Biologie (IFB) - Hôpital Purpan, Hôpital Purpan [Toulouse], CHU Toulouse [Toulouse]-CHU Toulouse [Toulouse]-Hôpital Purpan [Toulouse], CHU Toulouse [Toulouse], IFR 31 Louis Bugnard (IFR 31), Centre National de la Recherche Scientifique (CNRS)-Institut National de la Santé et de la Recherche Médicale (INSERM)-CHU Toulouse [Toulouse]-Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées, This work was supported by grants of INSERM, Fondation pour la Recherche Médicale (équipe FRM), the European Commission (HEPADIP project, Contract LSHM-CT-2005-018734) and ANR (PHYSIO 2006). C.C is granted by Agence National pour la Recherche. GSH is supported by a grant from the National Institutes of Health USA (DK052539)., Institut de Recherche en Cancérologie de Montpellier (IRCM - U1194 Inserm - UM), CRLCC Val d'Aurelle - Paul Lamarque-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Montpellier (UM), Franco-czech Laboratory for clinical research on obesity, Charles University [Prague] (CU)-Institut National de la Santé et de la Recherche Médicale (INSERM), Modélisation et ingéniérie des systèmes complexes pour le diagnostic (MISCD), BIO-RAD FRANCE HOLDING-Centre National de la Recherche Scientifique (CNRS), University of Cambridge School of Clinical Medicine, Addenbrooke's Hospital, Le Ster, Yves, Université Montpellier 1 (UM1)-Centre Hospitalier Régional Universitaire [Montpellier] (CHRU Montpellier)-Centre National de la Recherche Scientifique (CNRS), University of Virginia, Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées- Institut Fédératif de Recherche Bio-médicale Institution (IFR150)-Institut National de la Santé et de la Recherche Médicale (INSERM), Laboratoire de Biochimie [CHU Toulouse], Institut Fédératif de Biologie (IFB), Centre Hospitalier Universitaire de Toulouse (CHU Toulouse)-Centre Hospitalier Universitaire de Toulouse (CHU Toulouse)-Pôle Biologie [CHU Toulouse], Centre Hospitalier Universitaire de Toulouse (CHU Toulouse), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Centre Hospitalier Universitaire de Toulouse (CHU Toulouse)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Institut de Génétique Moléculaire de Montpellier (IGMM), Centre National de la Recherche Scientifique (CNRS)-Université de Montpellier (UM)

المصدر: Cell Metabolism
Cell Metabolism, Elsevier, 2009, 9 (4), pp.339-49. ⟨10.1016/j.cmet.2009.03.002⟩
Cell Metabolism, Elsevier, 2009, 9 (4), pp.339-349. ⟨10.1016/j.cmet.2009.03.002⟩
Cell Metabolism, 2009, 9 (4), pp.339-49. ⟨10.1016/j.cmet.2009.03.002⟩
Cell Metabolism, Elsevier, 2009, 9 (4), pp.339--49. ⟨10.1016/j.cmet.2009.03.002⟩

مصطلحات موضوعية: MESH: Signal Transduction, Chemokine CXCL5, [SDV.MHEP.PHY] Life Sciences [q-bio]/Human health and pathology/Tissues and Organs [q-bio.TO], Physiology, Glucose uptake, HUMDISEASE, Adipose tissue, White adipose tissue, MESH: Thiazolidinediones, Mice, 0302 clinical medicine, Adipose Tissue/cytology/drug effects/*metabolism Animals Chemokine CXCL5/deficiency/genetics/*metabolism Gene Expression Regulation/drug effects Humans *Insulin Resistance Macrophages/drug effects/metabolism Mice Obesity/*metabolism RNA, Messenger/genetics/metabolism Signal Transduction/drug effects Thiazolidinediones/pharmacology Tumor Necrosis Factor-alpha/pharmacology, MESH: Obesity, MESH: Animals, CXC chemokine receptors, Receptor, ComputingMilieux_MISCELLANEOUS, [SDV.MHEP.EM] Life Sciences [q-bio]/Human health and pathology/Endocrinology and metabolism, 0303 health sciences, [SDV.MHEP.EM]Life Sciences [q-bio]/Human health and pathology/Endocrinology and metabolism, MESH: Gene Expression Regulation, 3. Good health, MESH: Insulin Resistance, Adipose Tissue, medicine.symptom, MESH: Adipose Tissue, Signal Transduction, medicine.medical_specialty, MESH: Rosiglitazone, MESH: Chemokine CXCL5, 030209 endocrinology & metabolism, Inflammation, [SDV.CAN]Life Sciences [q-bio]/Cancer, Biology, Article, Rosiglitazone, 03 medical and health sciences, Insulin resistance, Internal medicine, medicine, [SDV.MHEP.PHY]Life Sciences [q-bio]/Human health and pathology/Tissues and Organs [q-bio.TO], Animals, Humans, [SDV.BBM]Life Sciences [q-bio]/Biochemistry, Molecular Biology, Obesity, RNA, Messenger, Molecular Biology, MESH: Mice, 030304 developmental biology, MESH: RNA, Messenger, MESH: Humans, Tumor Necrosis Factor-alpha, Macrophages, MESH: Macrophages, Cell Biology, medicine.disease, Insulin receptor, Endocrinology, Gene Expression Regulation, MESH: Tumor Necrosis Factor-alpha, biology.protein, Thiazolidinediones, Insulin Resistance

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a24a42232b845fd25849db6f64d1c16eTest
https://www.hal.inserm.fr/inserm-00375507Test

المؤلفون: Caroline S. S. Hyden, Nuno Rocha, Eleanor Raffan, Anni R. Thomsen, Inês Barroso, John Gregory, Maria A. Soos, Elaine Cochran, Stephen O'Rahilly, Mehul T. Dattani, P Gorden, J. Al Kaabi, Niels Morling, Robert K. Semple, Peter C. Hindmarsh, Antoinette Tuthill

المساهمون: Raffan, Eleanor [0000-0002-1403-3538], Barroso, Ines [0000-0001-5800-4520], O'Rahilly, Stephen [0000-0003-2199-4449], Semple, Robert [0000-0001-6539-3069], Apollo - University of Cambridge Repository

المصدر: Diabetologia

مصطلحات موضوعية: Receptor recycling, Adult, Male, medicine.medical_specialty, medicine.medical_treatment, Endocrinology, Diabetes and Metabolism, 030209 endocrinology & metabolism, Type A insulin resistance, Biology, medicine.disease_cause, Polymerase Chain Reaction, Article, 03 medical and health sciences, Young Adult, 0302 clinical medicine, Insulin resistance, Internal medicine, medicine, Genetics, Internal Medicine, Missense mutation, Humans, Protein Precursors, Receptor, Child, Cells, Cultured, 030304 developmental biology, 0303 health sciences, Mutation, Insulin, Diabetes, Infant, medicine.disease, Receptor, Insulin, 3. Good health, Insulin receptor, Endocrinology, Haplotypes, Africa, biology.protein, Mutagenesis, Site-Directed, Female, Insulin Resistance, Founder effect

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5739682db3e5e7e687e2808e0bb4a001Test