المؤلفون: Nicholas C. Wu, Gilberto C. Padron, Xueyong Zhu, Kaylee Kuzelka, Jacob R. Beal, Yiquan Wang, Beth M. Stadtmueller, Xin Chen, Ian A. Wilson, Timothy J. C. Tan, Meng Yuan, Joel Rivera-Cardona, Christopher B. Brooke

المصدر: bioRxiv
article-version (status) pre
article-version (number) 1
Nature Communications, Vol 12, Iss 1, Pp 1-10 (2021)
Nature Communications

مصطلحات موضوعية: 0301 basic medicine, Models, Molecular, Science, Protein domain, General Physics and Astronomy, Somatic hypermutation, Plasma protein binding, Immunoglobulin light chain, Crystallography, X-Ray, General Biochemistry, Genetics and Molecular Biology, Antibodies, Article, 03 medical and health sciences, 0302 clinical medicine, Protein Domains, Humans, Amino Acid Sequence, Peptide sequence, Binding selectivity, X-ray crystallography, Genetics, Multidisciplinary, biology, SARS-CoV-2, COVID-19, High-Throughput Nucleotide Sequencing, General Chemistry, Antibodies, Neutralizing, Complementarity Determining Regions, 030104 developmental biology, Antibody Formation, Spike Glycoprotein, Coronavirus, biology.protein, Angiotensin-Converting Enzyme 2, Antibody, Sequence motif, 030217 neurology & neurosurgery, Protein Binding

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc5289ed4f2dd2b49ed24da6bed5e59aTest
https://pubmed.ncbi.nlm.nih.gov/33532781Test

المؤلفون: Ryan P. Irving, Robin G. Bombardi, Randy A. Albrecht, Ian A. Wilson, Sandhya Bangaru, Shanshan Lang, Heng Zhang, Hillary A. Vanderven, Pavlo Gilchuk, Iuliia M. Gilchuk, Stephen J. Kent, Travis Nieusma, Pranathi Matta, James E. Crowe, Thomas G. Voss, Xueyong Zhu, Juergen A. Richt, Andrew B. Ward

المصدر: Nature Communications, Vol 9, Iss 1, Pp 1-15 (2018)
Nature Communications

مصطلحات موضوعية: 0301 basic medicine, medicine.drug_class, Viral protein, Swine, Science, viruses, 030106 microbiology, General Physics and Astronomy, Hemagglutinin (influenza), Hemagglutinin Glycoproteins, Influenza Virus, Cross Reactions, Monoclonal antibody, medicine.disease_cause, Antibodies, Viral, General Biochemistry, Genetics and Molecular Biology, Epitope, Antigenic drift, Article, 03 medical and health sciences, Epitopes, Orthomyxoviridae Infections, Influenza, Human, medicine, Influenza A virus, Animals, Humans, Neutralizing antibody, lcsh:Science, Swine Diseases, Multidisciplinary, biology, Influenza A Virus, H3N2 Subtype, Antibody-Dependent Cell Cytotoxicity, Antibodies, Monoclonal, food and beverages, General Chemistry, Virology, Antibodies, Neutralizing, 3. Good health, 030104 developmental biology, biology.protein, lcsh:Q, Antibody

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7b25d168b923eb482e8c9e2486e0d3cTest
http://link.springer.comTest/article/10.1038/s41467-018-04704-9

المؤلفون: Sijun Yang, Xueyong Zhu, Guang-Nian Zhao, Yan Zhang, Xiao-Jing Zhang, Junhong Guo, Peng Zhang, Xi Jiang, Pengcheng Luo, Hongliang Li, Pi-Xiao Wang

المصدر: Nature Communications, Vol 7, Iss 1, Pp 1-22 (2016)
Nature Communications

مصطلحات موضوعية: 0301 basic medicine, Genetically modified mouse, Male, medicine.medical_specialty, Science, General Physics and Astronomy, FOXO1, Biology, General Biochemistry, Genetics and Molecular Biology, Article, 03 medical and health sciences, Mice, Insulin resistance, Downregulation and upregulation, Internal medicine, medicine, Animals, Humans, Multidisciplinary, TNF Receptor-Associated Factor 3, Kinase, Fatty liver, General Chemistry, medicine.disease, MAP Kinase Kinase Kinases, Fatty Liver, Mice, Inbred C57BL, 030104 developmental biology, Endocrinology, medicine.anatomical_structure, Liver, Hepatocyte, Hepatocytes, Female, Steatosis, Insulin Resistance, Protein Binding, Signal Transduction

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c20c1a5d324efd393963b1e73839a207Test
https://doaj.orgTest/article/77626b712e6848859314d54a4402770d

المؤلفون: Chih Wei Lin, Richard A. Lerner, Corwin M. Nycholat, Xueyong Zhu, James C. Paulson, Ian A. Wilson, Andrew J. Thompson, Nicholas C. Wu, Jia Xie

المصدر: Nature Communications
Nature Communications, Vol 9, Iss 1, Pp 1-13 (2018)

مصطلحات موضوعية: 0301 basic medicine, Viral protein, viruses, Science, Reversion, General Physics and Astronomy, Mutagenesis (molecular biology technique), Hemagglutinin (influenza), Oligosaccharides, Hemagglutinin Glycoproteins, Influenza Virus, Biology, Receptor binding site, medicine.disease_cause, General Biochemistry, Genetics and Molecular Biology, Article, 03 medical and health sciences, Immune system, Antigen, Influenza, Human, medicine, Humans, lcsh:Science, Antigens, Viral, Genetics, Multidisciplinary, Binding Sites, Influenza A Virus, H3N2 Subtype, Epistasis, Genetic, Hydrogen Bonding, General Chemistry, 3. Good health, 030104 developmental biology, HEK293 Cells, Immune System, Mutation, biology.protein, Epistasis, Receptors, Virus, lcsh:Q, Protein Binding

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51d9b14b03353755f5c8639e76323d31Test
http://europepmc.org/articles/PMC5871881Test

المؤلفون: Xueyong Zhu, Xi Jiang, Lingchen Gao, Yichao Zhao, Xiang Wei, Xue-Hai Zhu, Hongliang Li, Yan-Xiao Ji, Xiao-Jing Zhang, Peng Zhang, Qinglin Yang, Jing Fang, Ke-Qiong Deng, Aibing Wang, Jun Pu, Lu Gao, Yan Zhang

المصدر: Nature Communications
Nature Communications, Vol 7, Iss 1, Pp 1-21 (2016)

مصطلحات موضوعية: Male, 0301 basic medicine, medicine.medical_specialty, Science, Transgene, Down-Regulation, General Physics and Astronomy, Cardiomegaly, Mice, Transgenic, Protein Serine-Threonine Kinases, Biology, Article, General Biochemistry, Genetics and Molecular Biology, Mice, 03 medical and health sciences, TANK-binding kinase 1, Downregulation and upregulation, Internal medicine, medicine, Animals, Humans, Myocyte, Myocytes, Cardiac, Protein kinase B, Mice, Knockout, Multidisciplinary, Intracellular Signaling Peptides and Proteins, General Chemistry, medicine.disease, Hedgehog signaling pathway, Rats, Mice, Inbred C57BL, Disease Models, Animal, Macaca fascicularis, 030104 developmental biology, Endocrinology, Heart failure, Cancer research, Female, Signal transduction, Protein Binding, Signal Transduction

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ae059a746db916eb9370a8abe1f7323Test
https://doi.org/10.1038/ncomms11432Test

المؤلفون: Carlos F. Barbas, Richard A. Lerner, Fujie Tanaka, Xueyong Zhu, Ian A. Wilson

المصدر: Journal of the American Chemical Society. 131(51)

مصطلحات موضوعية: biology, Aldolase A, Rational design, Direct observation, General Chemistry, Ketones, Biochemistry, Combinatorial chemistry, Small molecule, Antibodies, Catalysis, Article, Enamine, chemistry.chemical_compound, Colloid and Surface Chemistry, chemistry, biology.protein, Organic chemistry, Amine gas treating, Amines, Crystallization, Derivative (chemistry), Aldehyde-Lyases

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9aa25d13df56012b3be2b2b510647c52Test
https://pubmed.ncbi.nlm.nih.gov/19968282Test