المؤلفون: Mosaad S. Mohamed, Shahenda Mahgoub, Hend Medhat El-Shanbaky, Rania H. Abd El-Hameed, Sahar A. Ali

المصدر: Journal of Enzyme Inhibition and Medicinal Chemistry
article-version (VoR) Version of Record
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 36, Iss 1, Pp 977-986 (2021)

مصطلحات موضوعية: Chemokine, medicine.drug_class, Inflammation, RM1-950, 01 natural sciences, Anti-inflammatory, Lipoxygenase, Structure-Activity Relationship, 4-Butyrolactone, Heterocyclic Compounds, Drug Discovery, medicine, Humans, 15-LOX inhibitors, Lipoxygenase Inhibitors, Pyridazinone, anti-inflammatory, Pharmacology, chemistry.chemical_classification, Arachidonate 5-Lipoxygenase, biology, Cyclooxygenase 2 Inhibitors, Dose-Response Relationship, Drug, Molecular Structure, 010405 organic chemistry, Chemistry, Tumor Necrosis Factor-alpha, TNF-α inhibitor, Anti-Inflammatory Agents, Non-Steroidal, General Medicine, In vitro, 0104 chemical sciences, 010404 medicinal & biomolecular chemistry, Enzyme, Biochemistry, Cyclooxygenase 2, biology.protein, Tumor necrosis factor alpha, selective COX-2 inhibitor, Cyclooxygenase, Therapeutics. Pharmacology, medicine.symptom, Research Article, Research Paper

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19667daf6d13bb3c9f348e6d97dfab69Test
http://europepmc.org/articles/PMC8118430Test

المؤلفون: Afshin Zarghi, Mohammad Mahboubi-Rabbani

المصدر: Current Medicinal Chemistry. 28:1143-1175

مصطلحات موضوعية: Male, Leukotrienes, Peptidomimetic, Anti-Inflammatory Agents, Inflammation, Biology, 01 natural sciences, Biochemistry, 03 medical and health sciences, Lipoxygenase, chemistry.chemical_compound, Neoplasms, Drug Discovery, Gene expression, medicine, Animals, Humans, Cytotoxic T cell, Lipoxygenase Inhibitors, 0101 mathematics, 030304 developmental biology, Pharmacology, chemistry.chemical_classification, 0303 health sciences, Arachidonate 5-Lipoxygenase, Organic Chemistry, Cancer, medicine.disease, 010101 applied mathematics, Enzyme, chemistry, Cancer research, biology.protein, Molecular Medicine, Arachidonic acid, medicine.symptom

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::445a5fdbccc05b95edce1e6233b5ae4eTest
https://doi.org/10.2174/0929867326666191210104820Test

المؤلفون: Bivek Singh, Nour Ammar, Kuldeep Dhama, Sadeq A. Quraishi, Samuel Pecho-Silva, Mohammed Moustapha Anwar, Zareena Fathah, Alfonso J. Rodriguez-Morales, Rawan Sobhi Utt, Ranjit Sah, Areej Elba, Nohora Cristina Ayola-Serrano, Namrata Roy

المصدر: Inflammation Research

مصطلحات موضوعية: 0301 basic medicine, ARDS, Leukotrienes, Necrosis, Immunology, Review, Proinflammatory cytokine, 03 medical and health sciences, Tissue factor, 0302 clinical medicine, medicine, Animals, Humans, Lipoxygenase Inhibitors, Enzyme Inhibitors, Pharmacology, Inflammation, Leukotriene, Arachidonate 5-Lipoxygenase, Arachidonic Acid, biology, business.industry, SARS-CoV-2, 5-LOX inhibitors, Interleukins, COVID-19, medicine.disease, COVID-19 Drug Treatment, Cytokine release syndrome, 030104 developmental biology, Treatment Outcome, Virus Diseases, 030220 oncology & carcinogenesis, Arachidonate 5-lipoxygenase, biology.protein, 5-lipoxygenase, Cytokines, Tumor necrosis factor alpha, medicine.symptom, business, Cytokine Release Syndrome, CRS

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e784dbd316650c21de5dfb1c24d1d6a6Test
http://europepmc.org/articles/PMC8176665Test

المؤلفون: Zongduo Guo, Ping Zhang, Liu Liu, Yongbing Deng, Zhaohui He, Yidan Liang, Hong Chen, Zhaosi Zhang, Xiaochuan Sun

المصدر: Aging (Albany NY)

مصطلحات موضوعية: Male, Aging, subarachnoid hemorrhage, Morpholines, Administration, Oral, Apoptosis, Inflammation, Pharmacology, Phosphatidylinositol 3-Kinases, chemistry.chemical_compound, early brain injury, Downregulation and upregulation, Animals, Humans, Hydroxyurea, Medicine, LY294002, Lipoxygenase Inhibitors, 5-LOX, Protein kinase B, PI3K/AKT/mTOR pathway, Phosphoinositide-3 Kinase Inhibitors, Neurons, Arachidonate 5-Lipoxygenase, biology, business.industry, Cell Biology, Zileuton, Rats, Disease Models, Animal, Infusions, Intraventricular, chemistry, Chromones, Brain Injuries, Arachidonate 5-lipoxygenase, biology.protein, medicine.symptom, business, Proto-Oncogene Proteins c-akt, Signal Transduction, Research Paper, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ab727b90d24c0887f137ed7ce4dbcd6Test
https://doi.org/10.18632/aging.202869Test

المؤلفون: Minakshi A. Meshram, Venkata Rao Kaki, Priyanka N. Makhal, Utkarsha O. Bhise

المصدر: European journal of medicinal chemistry. 225

مصطلحات موضوعية: Inflammation, Pharmacology, chemistry.chemical_compound, Lipoxygenase, Drug Discovery, medicine, Animals, Humans, Lipoxygenase Inhibitors, Adverse effect, Biological Products, Arachidonate 5-Lipoxygenase, biology, Cyclooxygenase 2 Inhibitors, Molecular Structure, Chemistry, Organic Chemistry, General Medicine, medicine.disease, Cyclooxygenase 2, Rheumatoid arthritis, Arachidonate 5-lipoxygenase, biology.protein, Arachidonic acid, Cyclooxygenase, medicine.symptom, Pharmacophore

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ec66a875b168f9d4ad2cf49b8353df6Test
https://pubmed.ncbi.nlm.nih.gov/34479036Test

المؤلفون: Andreas Koeberle, Denis Séraphin, Stefan Lorkowski, Tiago Rodrigues, Oliver Werz, Daniela Schuster, Dimitri Bréard, Hermann Stuppner, Ida Cerqua, Antonietta Rossi, Simona Pace, Marta C. Marques, Alexander S. Mosig, Paul M. Jordan, Stephan Permann, Jana Gerstmeier, Martin Raasch, Gonçalo J. L. Bernardes, André Gollowitzer, Ulrike Garscha, Chau-Phi Dinh, Alexia Ville, Jean-Jacques Helesbeux, Fiorentina Roviezzo, Guillaume Viault, Elena Brunner, Pascal Richomme, Veronika Temml, Rossella Bilancia, Khaled Alsabil, Konstantin Loeser, Konstantin Neukirch

المساهمون: Neukirch, K., Alsabil, K., Dinh, C. -P., Bilancia, R., Raasch, M., Ville, A., Cerqua, I., Viault, G., Breard, D., Pace, S., Temml, V., Brunner, E., Jordan, P. M., Marques, M. C., Loeser, K., Gollowitzer, A., Permann, S., Gerstmeier, J., Lorkowski, S., Stuppner, H., Garscha, U., Rodrigues, T., Bernardes, G. J. L., Schuster, D., Seraphin, D., Richomme, P., Rossi, A., Mosig, A. S., Roviezzo, F., Werz, O., Helesbeux, J. -J., Koeberle, A., Neukirch, Konstantin [0000-0003-0630-1624], Dinh, Chau-Phi [0000-0002-3683-3472], Gollowitzer, André [0000-0003-1524-8298], Stuppner, Hermann [0000-0001-8862-0201], Rodrigues, Tiago [0000-0002-1581-5654], Bernardes, Gonçalo J L [0000-0001-6594-8917], Schuster, Daniela [0000-0002-9933-8938], Séraphin, Denis [0000-0002-0509-5788], Mosig, Alexander S [0000-0002-5687-2444], Werz, Oliver [0000-0002-5064-4379], Koeberle, Andreas [0000-0001-6269-5088], Apollo - University of Cambridge Repository, Bernardes, Gonçalo JL [0000-0001-6594-8917]

المصدر: Journal of Medicinal Chemistry

مصطلحات موضوعية: medicine.medical_treatment, Administration, Oral, Inflammation, Endogeny, Lipoxygenase Inhibitor, Pharmacology, Article, chemistry.chemical_compound, Structure-Activity Relationship, Immune system, Drug Discovery, medicine, Humans, Vitamin E, Lipoxygenase Inhibitors, Prostaglandin E2, Leukotriene, Arachidonate 5-Lipoxygenase, Dose-Response Relationship, Drug, Molecular Structure, Chemistry, Lipid signaling, Recombinant Protein, Recombinant Proteins, Molecular Docking Simulation, Molecular Medicine, medicine.symptom, Resolvin, medicine.drug, Human

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::197aa94407387a7b89fbecdcc110c28aTest
http://hdl.handle.net/11588/879642Test

المؤلفون: Drago Šubarić, Maja Molnar, Ivica Strelec, Melita Lončarić, Tihomir Moslavac, Valentina Pavić

المصدر: Biomolecules
Biomolecules, Vol 11, Iss 152, p 152 (2021)

مصطلحات موضوعية: plant extracts, Food spoilage, Lipoxygenase, lcsh:QR1-502, Inflammation, Stimulation, Review, Flowers, 01 natural sciences, Biochemistry, lcsh:Microbiology, 03 medical and health sciences, chemistry.chemical_compound, Inhibitory Concentration 50, medicine, Animals, Arachidonate 15-Lipoxygenase, Humans, Lipoxygenase Inhibitors, Molecular Biology, 030304 developmental biology, chemistry.chemical_classification, 0303 health sciences, Arachidonate 5-Lipoxygenase, Arachidonic Acid, lipoxygenase, polyphenols, biology, fungi, Fatty Acids, food and beverages, Polyphenols, Hydrogen Peroxide, 3. Good health, 0104 chemical sciences, Oxygen, Plant Leaves, 010404 medicinal & biomolecular chemistry, Enzyme, chemistry, Polyphenol, biology.protein, Fatty Acids, Unsaturated, Arachidonic acid, medicine.symptom, Oxidation-Reduction, Polyunsaturated fatty acid

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a98b336fb16017d9575d9f866f54f9efTest
http://europepmc.org/articles/PMC7911790Test

المؤلفون: Linlin Xie, Siqi Wang, Jing Liu, Ronghua Dai, Jun Liao, Xiaotong Cao, Teng Zhang, David Y.W. Lee, Ying Shang

المصدر: Phytomedicine. 93:153813

مصطلحات موضوعية: Male, Drug, media_common.quotation_subject, Lipoxygenase, Prostatic Hyperplasia, Pharmaceutical Science, Inflammation, Pharmacology, Inhibitory postsynaptic potential, chemistry.chemical_compound, Alkaloids, Berberine, Drug Discovery, medicine, Animals, Humans, Lipoxygenase Inhibitors, media_common, chemistry.chemical_classification, Arachidonate 5-Lipoxygenase, Cyclooxygenase 2 Inhibitors, Alkaloid, Palmatine, Hyperplasia, medicine.disease, Rats, Molecular Docking Simulation, Enzyme, Complementary and alternative medicine, chemistry, Cyclooxygenase 2, Molecular Medicine, medicine.symptom

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ee457f0880d26aa0d0f03cc56ca4ebdTest
https://doi.org/10.1016/j.phymed.2021.153813Test

المؤلفون: Ewgenij Proschak, Dieter Steinhilber, Angelo Sala, G. Enrico Rovati

المساهمون: Publica

المصدر: Biochemical Pharmacology. 158:161-173

مصطلحات موضوعية: 0301 basic medicine, Epoxide hydrolase 2, medicine.drug_class, Pain, Inflammation, Pharmacology, Prostaglandin E synthase, Biochemistry, Anti-inflammatory, 03 medical and health sciences, medicine, Animals, Humans, Lipoxygenase Inhibitors, Receptor, Prostaglandin-E Synthases, Arachidonate 5-Lipoxygenase, Arachidonic Acid, Cyclooxygenase 2 Inhibitors, biology, business.industry, Anti-Inflammatory Agents, Non-Steroidal, Lipid signaling, 030104 developmental biology, Cyclooxygenase 2, biology.protein, Thromboxane-A synthase, Cyclooxygenase, medicine.symptom, business, Metabolic Networks and Pathways

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f50364eb95a3e7e6470fe95ab51459d1Test
https://doi.org/10.1016/j.bcp.2018.10.007Test

المؤلفون: Simona Pace, Daniela Schuster, Marc Birringer, Maria Wallert, Christina Weinigel, Hermann Stuppner, Denis Séraphin, David Guilet, Veronika Temml, Martin Raasch, Silke Rummler, Helmut Pein, Fiorentina Roviezzo, Jean-Jacques Helesbeux, Rosella Bilancia, Lidia Sautebin, Stefanie König, Guillaume Viault, Chau-Phi Dinh, Alexia Ville, Ulrike Garscha, Birgit Waltenberger, Alexander S. Mosig, Stefan Lorkowski, Andreas Koeberle, Fabiana Troisi, Pascal Richomme, Oliver Werz, Khaled Alsabil, Antonietta Rossi, Konstantin Neukirch

المساهمون: Pein, Helmut, Ville, Alexia, Pace, Simona, Temml, Veronika, Garscha, Ulrike, Raasch, Martin, Alsabil, Khaled, Viault, Guillaume, Dinh, Chau-Phi, Guilet, David, Troisi, Fabiana, Neukirch, Konstantin, König, Stefanie, Bilancia, Rosella, Waltenberger, Birgit, Stuppner, Hermann, Wallert, Maria, Lorkowski, Stefan, Weinigel, Christina, Rummler, Silke, Birringer, Marc, Roviezzo, Fiorentina, Sautebin, Lidia, Helesbeux, Jean-Jacque, Séraphin, Deni, Mosig, Alexander S., Schuster, Daniela, Rossi, Antonietta, Richomme, Pascal, Werz, Oliver, Koeberle, Andreas, Substances d'Origine Naturelle et Analogues Structuraux (SONAS), Université d'Angers (UA)

المصدر: Nature Communications, Vol 9, Iss 1, Pp 1-17 (2018)
Nature Communications
Nature Communications, Nature Publishing Group, 2018, 9 (1), pp.3834. ⟨10.1038/s41467-018-06158-5⟩

مصطلحات موضوعية: 0301 basic medicine, [SDV]Life Sciences [q-bio], Metabolite, medicine.medical_treatment, General Physics and Astronomy, Pharmacology, chemistry.chemical_compound, Mice, 0302 clinical medicine, Leukocytes, Vitamin E, Lipoxygenase Inhibitors, lcsh:Science, Multidisciplinary, biology, Chemistry (all), Middle Aged, Recombinant Proteins, 3. Good health, Liver, 030220 oncology & carcinogenesis, Arachidonate 5-lipoxygenase, Metabolome, medicine.symptom, Bronchial Hyperreactivity, Adult, Cell signaling, Adolescent, Cell Survival, Science, Inflammation, Peritonitis, General Biochemistry, Genetics and Molecular Biology, 03 medical and health sciences, Physics and Astronomy (all), Inhibitory Concentration 50, Young Adult, Immune system, medicine, Animals, Humans, Aged, Biochemistry, Genetics and Molecular Biology (all), Arachidonate 5-Lipoxygenase, Cell-Free System, General Chemistry, Lipid signaling, 030104 developmental biology, chemistry, biology.protein, lcsh:Q

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bfee7afdff0d4990f14ad8886b080055Test
http://link.springer.com/article/10.1038/s41467-018-06158-5Test