نتائج البحث - "Giovanna Chiorino"

1

Targeting p63 Upregulation Abrogates Resistance to MAPK Inhibitors in Melanoma

المؤلفون: Giovanna Chiorino, Monica Rodolfo, Tania Maffucci, Daniele Bergamaschi, Lucia Fraile Garcia, Christian Posch, Elisabetta Vergani, Catherine A. Harwood, Viviana Mannella, Tiffanie-Marie Borg, Ankit Kumar Patel, Andrea Maurichi, Luke Gammon, Maria Scatolini, Rubeta Nishat Matin

المصدر: Cancer research. 80(12)

مصطلحات موضوعية: 0301 basic medicine, MAPK/ERK pathway, Male, Cancer Research, F-Box-WD Repeat-Containing Protein 7, Skin Neoplasms, medicine.medical_treatment, Drug resistance, Piperazines, Targeted therapy, 0302 clinical medicine, Antineoplastic Combined Chemotherapy Protocols, Medicine, Melanoma, Skin, Aged, 80 and over, biology, Imidazoles, Proto-Oncogene Proteins c-mdm2, Middle Aged, Ubiquitin ligase, Up-Regulation, Gene Expression Regulation, Neoplastic, Oncology, 030220 oncology & carcinogenesis, Mdm2, Female, Adult, Proto-Oncogene Proteins B-raf, 03 medical and health sciences, Young Adult, Downregulation and upregulation, Cell Line, Tumor, Humans, neoplasms, Protein Kinase Inhibitors, Aged, Mitogen-Activated Protein Kinase Kinases, Dose-Response Relationship, Drug, business.industry, Tumor Suppressor Proteins, medicine.disease, 030104 developmental biology, Apoptosis, Drug Resistance, Neoplasm, Mutation, Proteolysis, biology.protein, Cancer research, business, Transcription Factors

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e54d74ec9ad2fb13d2ce515d9138937aTest
https://pubmed.ncbi.nlm.nih.gov/32291316Test

2

The IKK/NF-κB signaling pathway requires Morgana to drive breast cancer metastasis

المصدر: Nature Communications, Vol 8, Iss 1, Pp 1-17 (2017)
Nature Communications

مصطلحات موضوعية: 0301 basic medicine, Science, General Physics and Astronomy, Apoptosis, Breast Neoplasms, IκB kinase, Biology, General Biochemistry, Genetics and Molecular Biology, Article, Metastasis, Gene product, 03 medical and health sciences, Mice, 0302 clinical medicine, Breast cancer, Cell Line, Tumor, medicine, Gene silencing, Animals, Humans, Neoplasm Metastasis, lcsh:Science, Cell Proliferation, Mice, Inbred BALB C, Multidisciplinary, NF-kappa B, General Chemistry, Phosphate-Binding Proteins, medicine.disease, Primary tumor, I-kappa B Kinase, Gene Expression Regulation, Neoplastic, IκBα, 030104 developmental biology, 030220 oncology & carcinogenesis, Cancer cell, Cancer research, lcsh:Q, Female, Carrier Proteins, Molecular Chaperones, Signal Transduction

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d12f258f4a97fb7dfa25be4704f10beTest
https://doaj.org/article/12fe3e6cb2cb4e56ad2f805e25c15661Test

3

Gene and microRNA modulation upon trabectedin treatment in a human intrahepatic cholangiocarcinoma paired patient derived xenograft and cell line

المؤلفون: Massimo Aglietta, Giuliana Cavalloni, Francesco Leone, Giovanna Chiorino, Paola Ostano, Caterina Peraldo Neia

المصدر: Oncotarget

مصطلحات موضوعية: 0301 basic medicine, MAPK/ERK pathway, Microarray, Syk, Apoptosis, Dioxoles, Bioinformatics, Cholangiocarcinoma, Transcriptome, Mice, 03 medical and health sciences, 0302 clinical medicine, Cell Movement, Cell Line, Tumor, Tetrahydroisoquinolines, microRNA, medicine, Animals, Cluster Analysis, Humans, Gene silencing, Antineoplastic Agents, Alkylating, Trabectedin, Intrahepatic cholangiocarcinoma, business.industry, Xenograft Model Antitumor Assays, microarray, silencing, trabectedin, Gene Expression Regulation, Neoplastic, MicroRNAs, Gene Ontology, 030104 developmental biology, Bile Duct Neoplasms, Oncology, Tumor progression, 030220 oncology & carcinogenesis, Cancer research, business, Research Paper, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf6bd7e75a8ea45ae86e35714638391bTest
https://doi.org/10.18632/oncotarget.13575Test

4

PARP1 expression drives the synergistic antitumor activity of trabectedin and PARP1 inhibitors in sarcoma preclinical models

المصدر: Molecular Cancer
Molecular Cancer, Vol 16, Iss 1, Pp 1-15 (2017)

مصطلحات موضوعية: 0301 basic medicine, Cancer Research, Cell cycle checkpoint, Poly (ADP-Ribose) Polymerase-1, Apoptosis, Pharmacology, Piperazines, Mice, chemistry.chemical_compound, 0302 clinical medicine, PARP1, Olaparib, Predictive biomarkers, Tetrahydroisoquinolines, Trabectedin, Comparative Genomic Hybridization, Sarcoma, lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens, Gene Expression Regulation, Neoplastic, Oncology, 030220 oncology & carcinogenesis, Molecular Medicine, medicine.symptom, medicine.drug, DNA damage, Dioxoles, Biology, lcsh:RC254-282, 03 medical and health sciences, Cell Line, Tumor, Biomarkers, Tumor, medicine, Animals, Humans, Gene silencing, Bone and soft tissue sarcomas, DNA-damaging agents, Drug synergism, PARP1 inhibitors, Research, Xenograft Model Antitumor Assays, Molecular medicine, 030104 developmental biology, chemistry, Mechanism of action, Cancer research, Phthalazines, DNA Damage

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0bac95fcb4d78dfaa034b6b64a689629Test
http://hdl.handle.net/2318/1636100Test

5

c-Myc Phosphorylation Is Required for Cellular Response to Oxidative Stress

المؤلفون: Massimo Loda, Francesco Fiorentino, Maurizio Fanciulli, Giovanna Chiorino, Annamaria Biroccio, Alessandro Porrello, Gabriella Zupi, Barbara Benassi

المصدر: Molecular Cell. 21:509-519

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42f85ac386f119cb69bb4c17aaf0461aTest
https://doi.org/10.1016/j.molcel.2006.01.009Test

6

Glutathione Influences c-Myc-induced Apoptosis in M14 Human Melanoma Cells

المؤلفون: M.R. Ciriolo, Giovanna Chiorino, Gabriella Zupi, Sarah Amodei, Annamaria Biroccio, Barbara Benassi, Giuseppe Filomeni, Sergio Marchini, Giuseppe Rotilio

المصدر: Journal of Biological Chemistry. 277:43763-43770

مصطلحات موضوعية: GPX1, Time Factors, GPX3, Glutathione reductase, Apoptosis, reactive oxygen metabolite, NADPH Oxidoreductases, Biochemistry, chemistry.chemical_compound, Cytosol, caspase 3, Tumor Cells, Cultured, NADH, NADPH Oxidoreductases, glutathione, caspase 9, Melanoma, Oligonucleotide Array Sequence Analysis, glutamate cysteine ligase, chemistry.chemical_classification, Cultured, biology, oncogene c myc, Blotting, Cytochrome c, article, Flow Cytometry, Enzymes, enzyme activity, Anti-Bacterial Agents, Tumor Cells, Cell biology, cytochrome c, glutathione ethyl ester, Glutathione Reductase, priority journal, Caspases, Doxycycline, Western, melanoma cell, Programmed cell death, Thioredoxin-Disulfide Reductase, Cells, Glutamate-Cysteine Ligase, Blotting, Western, Down-Regulation, Cytochrome c Group, Proto-Oncogene Proteins c-myc, Oxidation, acetylcysteine, reduced nicotinamide adenine dinucleotide phosphate, Humans, controlled study, human, Settore BIO/10, Molecular Biology, Genetic engineering, Metabolism, glutathione reductase, apoptosis, enzyme activation, gene expression, human cell, metabolism, oxidation reduction reaction, Caspase 3, Caspase 9, Glutathione, Reactive Oxygen Species, Reactive oxygen species, Cell Biology, Molecular biology, chemistry, NADH, biology.protein

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42219fdc21552ca79c0505d048dd8b72Test
https://doi.org/10.1074/jbc.m207684200Test

7

Cell cycle phase perturbations and apoptosis in tumour cells induced by aplidine

المؤلفون: Eugenio Erba, Jose Jimeno, I Muradore, Giovanna Chiorino, L Bassano, Paolo Ubezio, G Di Liberti, Maria Alfonsina Desiderio, A.M. Codegoni, Maurizio D'Incalci, Sara Vignati, Glynn Faircloth

المصدر: British Journal of Cancer

مصطلحات موضوعية: Cancer Research, Programmed cell death, Aplidine, Antineoplastic Agents, Biology, Peptides, Cyclic, Cell cycle phase, natural compound, Depsipeptides, medicine, Putrescine, Tumor Cells, Cultured, Humans, Experimental Therapeutics, Cytotoxicity, Depsipeptide, Leukemia, Kinase, Cell Cycle, apoptosis, Cell cycle, Cell biology, Oncology, Mechanism of action, Apoptosis, Immunology, medicine.symptom

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e7bbcdb2d255e5e233deab16fb810c0Test
http://europepmc.org/articles/PMC2375382Test

8

iASPP is a novel autophagy inhibitor in keratinocytes

المؤلفون: Gary Warnes, Claudio Raimondi, Catherine A. Harwood, O Akinduro, Paolo Sanza, Daniele Bergamaschi, Anissa Chikh, Carolyn Byrne, Giovanna Chiorino

المصدر: Journal of cell science. 127(Pt 14)

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a65546173371d626542c2b9dc633a14aTest
https://pubmed.ncbi.nlm.nih.gov/35876107Test

9

Characterization of a new trabectedin-resistant myxoid liposarcoma cell line that shows collateral sensitivity to methylating agents

مصطلحات موضوعية: Cancer Research, DNA Repair, Oncogene Proteins, Fusion, Ultraviolet Rays, DNA repair, Apoptosis, Dioxoles, Biology, Fusion gene, Cell Line, Tumor, Tetrahydroisoquinolines, CCAAT-Enhancer-Binding Protein-alpha, Temozolomide, medicine, Humans, Settore BIO/10, Promoter Regions, Genetic, Antineoplastic Agents, Alkylating, DNA Modification Methylases, Trabectedin, Genetics, CCAAT-Enhancer-Binding Protein-beta, Tumor Suppressor Proteins, Promoter, DNA Methylation, Liposarcoma, Myxoid, Fibronectins, Dacarbazine, Serum Amyloid P-Component, C-Reactive Protein, DNA Repair Enzymes, Oncology, Drug Resistance, Neoplasm, Cell culture, DNA methylation, Cancer research, RNA-Binding Protein FUS, Chromatin immunoprecipitation, Transcription Factor CHOP, Signal Transduction, Nucleotide excision repair, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a83c1380bfac3594fb417e4b96a40a9Test
http://hdl.handle.net/2108/64209Test

10

Altered molecular pathways in melanocytic lesions

المؤلفون: Maria, Scatolini, Maurizia Mello, Grand, Enrico, Grosso, Tiziana, Venesio, Alberto, Pisacane, Antonella, Balsamo, Roberta, Sirovich, Mauro, Risio, Giovanna, Chiorino

المصدر: International journal of cancer. 126(8)

مصطلحات موضوعية: Adult, Male, Skin Neoplasms, Reverse Transcriptase Polymerase Chain Reaction, Gene Expression Profiling, Gene Expression, Apoptosis, Middle Aged, Humans, Female, Melanoma, Nevus, Aged, Oligonucleotide Array Sequence Analysis

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=pmid________::2e90e93c073f2842a6c2d3aa8e3c65aeTest
https://pubmed.ncbi.nlm.nih.gov/19795447Test

تنقيح النتائج