Major depression and generalized anxiety disorder among HTLV-I/II infected former blood donors
| العنوان: | Major depression and generalized anxiety disorder among HTLV-I/II infected former blood donors |
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| المؤلفون: | Zhanna Kaidarova, Dee Behan, S Hutching, Edward L Murphy, Anne M. Guiltinan, Mandi Kaiser, Elane Moore, Cheryl Marosi, Deborah DeVita |
| المصدر: | Retrovirology, Vol 8, Iss Suppl 1, p A70 (2011) Retrovirology Guiltinan, Anne M; Kaidarova, Zhanna; Behan, Dee; Marosi, Cheryl; Hutching, Sheila; Kaiser, Mandi; et al.(2011). Major depression and generalized anxiety disorder among HTLV-I/II infected former blood donors. Retrovirology, 8(Suppl 1), A70. doi: http://dx.doi.org/10.1186/1742-4690-8-S1-A70Test. Retrieved from: http://www.escholarship.org/uc/item/5mm3h88pTest |
| بيانات النشر: | BMC, 2011. |
| سنة النشر: | 2011 |
| مصطلحات موضوعية: | Male, lcsh:Immunologic diseases. Allergy, medicine.medical_specialty, Generalized anxiety disorder, viruses, Population, Blood Donors, Article, immune system diseases, hemic and lymphatic diseases, Virology, Internal medicine, Humans, Medicine, Htlv i ii, Psychiatry, education, Depression (differential diagnoses), Aged, Depressive Disorder, Major, education.field_of_study, business.industry, Confounding, virus diseases, Middle Aged, medicine.disease, Anxiety Disorders, HTLV-I Infections, Infectious Diseases, Blood donor, HTLV-II Infections, Meeting Abstract, Population data, Female, business, lcsh:RC581-607 |
| الوصف: | Other studies have reported high rates of depression and anxiety among human T-lymphotropic virus Type I (HTLV-I)-infected subjects and have even suggested that HTLV-I causes psychiatric disease.We interviewed HTLV-I, HTLV-II, and demographically similar HTLV-seronegative blood donors with the Mini-International Neuropsychiatric Interview. Prevalences of major depression and generalized anxiety disorder in each group were calculated and compared to published US population data. Adjusted odds ratios (aOR) and 95% confidence intervals (CIs) controlling for educational achievement, alcohol intake, and self-reported health status were calculated with multivariate logistic regression.Major depression was diagnosed in five (5.4%) of 93 HTLV-I-positive subjects (aOR, 2.19; 95% CI, 0.63-7.55) and 17 (6.6%) of 256 HTLV-II-positive subjects (aOR, 1.61; 95% CI, 0.66-3.927), compared to 12 (2.1%) of 585 HTLV-seronegative blood donors. The prevalence of major depression among infected subjects was comparable to the 6.7% prevalence in the US general population. Generalized anxiety disorder was diagnosed in five (5.4%) HTLV-I-positive subjects (OR, 2.32; 95% CI, 0.74-7.26) and 12 (4.7%) HTLV-II-positive subjects (OR, 1.65; 95% CI, 0.68-4.01), compared to 15 (2.6%) seronegative subjects and 3.1% in the US general population.Major depression and generalized anxiety disorder were not significantly more prevalent among HTLV-I- and HTLV-II-infected former blood donors after controlling for health status and other confounding variables. HTLV-seronegative blood donors had lower prevalences of these conditions than the US population, probably due to a "healthy blood donor effect." |
| وصف الملف: | application/pdf |
| اللغة: | English |
| تدمد: | 1742-4690 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9bcafd2f35d838813e7aebde2df4b45Test https://doaj.org/article/d06b39cdd7f54c4596628448763a00f3Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....e9bcafd2f35d838813e7aebde2df4b45 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 17424690 |
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