المؤلفون: Refolo MG1, D'Alessandro R, Malerba N, Laezza C, Bifulco M, Messa C, Caruso MG, Notarnicola M, Tutino V.

المساهمون: Refolo Maria, Grazia, D'Alessandro, Rosalba, Malerba, Natascia, Laezza, Chiara, Bifulco, Maurizio, Messa, Caterina, Caruso Maria, Gabriella, Notarnicola, Maria, Tutino, Valeria

المصدر: Journal of cellular physiology
(2015). doi:10.1002/jcp.25026
info:cnr-pdr/source/autori:Refolo MG1, D'Alessandro R, Malerba N, Laezza C, Bifulco M, Messa C, Caruso MG, Notarnicola M, Tutino V./titolo:Anti Proliferative and Pro Apoptotic Effects of Flavonoid Quercetin Are Mediated by CB1 Receptor in Human Colon Cancer Cell Lines./doi:10.1002%2Fjcp.25026/rivista:Journal of cellular physiology (Print)/anno:2015/pagina_da:/pagina_a:/intervallo_pagine:/volume

مصطلحات موضوعية: Physiology, Clinical Biochemistry, Antineoplastic Agents, Apoptosis, Adenocarcinoma, Antineoplastic Agent, Receptor, Cannabinoid, CB1, Cell Movement, CB1 receptor, Wnt/?-catenin pathway, colon cancer, intracellular signaling, quercetin, Phytogenic, Humans, heterocyclic compounds, Cannabinoid, Antineoplastic Agents, Phytogenic, Caco-2 Cells, Cannabinoid Receptor Agonists, Cell Proliferation, Colonic Neoplasms, Quercetin, Signal Transduction, Up-Regulation, Medicine (all), Cell Biology, Caco-2 Cell, Colonic Neoplasm, Cannabinoid Receptor Agonist, food and beverages, Apoptosi, CB1, lipids (amino acids, peptides, and proteins), Human, Receptor

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::d0dee8932667db6e133aa701d261de19Test
http://hdl.handle.net/11588/747074Test

المؤلفون: Di Marzo V., Melck D., Orlando P., Bisogno T., Zagoory O., Bifulco M., Vogel Z., De Petrocellis L.

المصدر: Biochemical journal (Lond., 1984) 358 (2001): 249–255. doi:10.1042/0264-6021:3580249
info:cnr-pdr/source/autori:Di Marzo V., Melck D., Orlando P., Bisogno T., Zagoory O., Bifulco M., Vogel Z., De Petrocellis L./titolo:Palmitoylethanolamide inhibits the expression of fatty acid amide hydrolase and enhances the anti-proliferative effect of anandamide in human breast cancer cells/doi:10.1042%2F0264-6021:3580249/rivista:Biochemical journal (Lond., 1984)/anno:2001/pagina_da:249/pagina_a:255/intervallo_pagine:249–255/volume:358

مصطلحات موضوعية: Polyunsaturated Alkamides, Receptors, Drug, Blotting, Western, receptors, Antineoplastic Agents, Breast Neoplasms, Arachidonic Acids, Palmitic Acids, Transfection, arvanil, Amidohydrolases, Glycerides, Inhibitory Concentration 50, Cannabinoid Receptor Modulators, Cyclic AMP, Tumor Cells, Cultured, Animals, Humans, Receptors, Cannabinoid, Camphanes, Dose-Response Relationship, Drug, Cannabinoids, Reverse Transcriptase Polymerase Chain Reaction, Hydrolysis, Anti-Inflammatory Agents, Non-Steroidal, Colforsin, food and beverages, Amides, 2-arachidonoylglycerol, cell proliferation, Ethanolamines, COS Cells, Pyrazoles, lipids (amino acids, peptides, and proteins), Capsaicin, Cell Division, Endocannabinoids, Protein Binding, Research Article

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::156b5b3c9596b3846a7df48b82bbff5dTest
https://pubmed.ncbi.nlm.nih.gov/11485574Test

المؤلفون: Manuela Grimaldi, Maurizio Bifulco, Maria Proto, Verdiana Covelli, Mohammad Firoznezhad, Rosario Randino, Anna Maria D'Ursi, Patrizia Gazzerro, Manuela Rodriquez, Veronica De Simone, Gianluca Matteoli

المساهمون: Covelli, V., Grimaldi, M., Randino, R., Firoznezhad, M., Proto, M. C., De Simone, V., Matteoli, G., Gazzerro, P., Bifulco, M., D'Ursi, A. M., Rodriquez, M.

المصدر: Molecules, Vol 26, Iss 7146, p 7146 (2021)
Molecules; Volume 26; Issue 23; Pages: 7146
Molecules

مصطلحات موضوعية: Colorectal cancer, FPPS, N6-benzyladenosine derivatives, Adenosine, Animals, Antineoplastic Agents, Apoptosis, Cell Proliferation, Cell Survival, Colorectal Neoplasms, Computer Simulation, Drug Screening Assays, Antitumor, Geranyltranstransferase, HCT116 Cells, Humans, Mevalonic Acid, Mice, Structure-Activity Relationship, User-Computer Interface, Chemistry, Multidisciplinary, FARNESYL DIPHOSPHATE SYNTHASE, Farnesyl pyrophosphate, Pharmaceutical Science, Drug Screening Assays, Analytical Chemistry, chemistry.chemical_compound, QD241-441, colorectal cancer, Drug Discovery, CYTOKININ, chemistry.chemical_classification, ATP synthase, biology, TRANSFER DIFFERENCE NMR, APOPTOSIS, Chemistry, N6-ISOPENTENYLADENOSINE, Biochemistry, Chemistry (miscellaneous), Physical Sciences, Molecular Medicine, Life Sciences & Biomedicine, medicine.drug, Biochemistry & Molecular Biology, NUCLEOSIDES, ISOPRENOID END-PRODUCT, Article, CELL-PROLIFERATION, Prenylation, In vivo, medicine, Viability assay, BIOLOGICAL EVALUATION, Physical and Theoretical Chemistry, Science & Technology, Organic Chemistry, Antitumor, In vitro, Enzyme, chemistry, biology.protein, LIGAND

وصف الملف: Electronic; application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd05b972cb880efd7575b524e110c2e6Test
https://doi.org/10.3390/molecules26237146Test

المؤلفون: Elena Ciaglia, Michela Buonocore, Patrizia Gazzerro, Alessandra Tosco, Ilaria Stillitano, Rosario Randino, Mario Scrima, Mario Abate, Anna Maria D'Ursi, Manuela Grimaldi, Manuela Rodriquez, Verdiana Covelli, Maurizio Bifulco

المساهمون: Grimaldi, M., Randino, R., Ciaglia, E., Scrima, M., Buonocore, M., Stillitano, I., Abate, M., Covelli, V., Tosco, A., Gazzerro, P., Bifulco, M., Rodriquez, M., D'Ursi, A. M.

مصطلحات موضوعية: NMR enzymatic assay, Cell Survival, Drug Evaluation, Preclinical, Farnesyl pyrophosphate, Antineoplastic Agents, Adenosine derivatives, 01 natural sciences, Biochemistry, Structure-Activity Relationship, Isoprenoid, chemistry.chemical_compound, Drug Discovery, Humans, Cytotoxic T cell, Enzyme Inhibitors, Nuclear Magnetic Resonance, Biomolecular, Molecular Biology, Cells, Cultured, Cell Proliferation, chemistry.chemical_classification, Dose-Response Relationship, Drug, Molecular Structure, ATP synthase, biology, 010405 organic chemistry, FPPS, Organic Chemistry, Geranyltranstransferase, Isoprenoids, Terpenoid, In vitro, 0104 chemical sciences, Molecular Docking Simulation, 010404 medicinal & biomolecular chemistry, Enzyme, chemistry, biology.protein, Mevalonate pathway, Drug Screening Assays, Antitumor, Adenosine derivative, Ex vivo

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96eaee52f68d9ad9f4b3f9ec7e52b607Test
http://hdl.handle.net/11386/4736255Test

المؤلفون: Mariarosaria Santillo, Tiziana Annella, Rosalba Serù, Mario Vitale, S. Iossa, Paolo Mondola, Maurizio Bifulco, Anna Gioielli

المساهمون: Santillo, Mariarosaria, Mondola, Paolo, Gioielli, A., Seru, R., Iossa, S., Annella, T., Vitale, M., Bifulco, M., Serù, R., Vitale, Mario

المصدر: Biochemical and Biophysical Research Communications. 229:739-745

مصطلحات موضوعية: Mutant, Organophosphonates, Protein Prenylation, Biophysics, Cancer therapy, Antineoplastic Agents, medicine.disease_cause, Biochemistry, 3T3 cells, Mice, Prenylation, medicine, Animals, Lovastatin, Molecular Biology, chemistry.chemical_classification, Reactive oxygen species, Lipid peroxide, Chemistry, 3T3 Cells, Cell Biology, Molecular biology, Oxidative Stress, Cell Transformation, Neoplastic, Genes, ras, medicine.anatomical_structure, lipids (amino acids, peptides, and proteins), Oxidative stress, medicine.drug

وصف الملف: STAMPA

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f13f223bb25066915804880ef31bbb2bTest
https://doi.org/10.1006/bbrc.1996.1874Test

المؤلفون: Simona Pisanti, Patrizia Gazzerro, Maria Proto, Maurizio Bifulco, Anna Maria Malfitano, Antonietta Santoro, Giuseppina Gangemi, Chiara Laezza, Elena Ciaglia

المساهمون: Gazzerro, P., Proto, M. C., Gangemi, G., Malfitano, A. M., Ciaglia, E., Pisanti, S., Santoro, A., Laezza, C., Bifulco, M.

المصدر: Pharmacological reviews (2012).
info:cnr-pdr/source/autori:Gazzerro P, Proto MC, Gangemi G, Malfitano AM, Ciaglia E, Pisanti S, Santoro A, Laezza C, Bifulco M./titolo:Pharmacological Actions of Statins: A Critical Appraisal in the Management of Cancer./doi:/rivista:Pharmacological reviews/anno:2012/pagina_da:/pagina_a:/intervallo_pagine:/volume

مصطلحات موضوعية: Statin, medicine.drug_class, medicine.medical_treatment, Context (language use), Antineoplastic Agents, Pharmacology, Bioinformatics, Neuroprotection, Antineoplastic Agent, Neoplasms, medicine, Animals, Anticarcinogenic Agents, Humans, Drug Interactions, cardiovascular diseases, Anticarcinogenic Agent, business.industry, Animal, Cancer, nutritional and metabolic diseases, medicine.disease, Coronary heart disease, Clinical trial, Critical appraisal, Drug Interaction, Molecular Medicine, lipids (amino acids, peptides, and proteins), Hydroxymethylglutaryl-CoA Reductase Inhibitor, Hydroxymethylglutaryl-CoA Reductase Inhibitors, business, Adjuvant, Human

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3f13b33138e6dc68fd9392080a564e6Test
http://hdl.handle.net/11386/3324078Test

المؤلفون: Anna Maria Malfitano, Giuseppe Saccomanni, Adriano Martinelli, Valentina Lucchesi, Tiziano Tuccinardi, Francesca Castelli, Simone Bertini, Antonio Giordano, Alessia Ligresti, Clementina Manera, Maurizio Bifulco, Flavio Rizzolio, Chiara Laezza, Vincenzo Di Marzo, Marco Macchia

المساهمون: Manera, C, Saccomanni, G, Malfitano, Am, Bertini, S, Castelli, F, Laezza, C, Ligresti, A, Lucchesi, V, Tuccinardi, T, Rizzolio, F, Bifulco, M, Di Marzo, V, Giordano, A, Macchia, M, Martinelli, A.

المصدر: European journal of medicinal chemistry (Online) (2012).
info:cnr-pdr/source/autori:Manera C, Saccomanni G, Malfitano AM, Bertini S, Castelli F, Laezza C, Ligresti A, Lucchesi V, Tuccinardi T, Rizzolio F, Bifulco M, Di Marzo V, Giordano A, Macchia M, Martinelli A./titolo:Rational design, synthesis and anti-proliferative properties of new CB2 selective cannabinoid receptor ligands: an investigation of the 1,8-naphthyridin-2(1H)-one scaffold./doi:/rivista:European journal of medicinal chemistry (Online)/anno:2012/pagina_da:/pagina_a:/intervallo_pagine:/volume
European journal of medicinal chemistry (2012).
info:cnr-pdr/source/autori:Manera C, Saccomanni G, Malfitano AM, Bertini S, Castelli F, Laezza C, Ligresti A, Lucchesi V, Tuccinardi T, Rizzolio F, Bifulco M, Di Marzo V, Giordano A, Macchia M, Martinelli A./titolo:Rational design, synthesis and anti-proliferative properties of new CB2 selective cannabinoid receptor ligands: an investigation of the 1,8-naphthyridin-2(1H)-one scaffold./doi:/rivista:European journal of medicinal chemistry/anno:2012/pagina_da:/pagina_a:/intervallo_pagine:/volume

مصطلحات موضوعية: Anti-proliferative, Cannabinoid, CB1 receptor, CB2 receptor, Antineoplastic Agents, Cell Line, Tumor, Cell Proliferation, Humans, Ligands, Models, Molecular, Molecular Conformation, Naphthyridines, Receptor, Cannabinoid, CB1, Receptor, Cannabinoid, CB2, Substrate Specificity, Chemistry Techniques, Synthetic, Drug Design, Drug Discovery3003 Pharmaceutical Science, Organic Chemistry, Pharmacology, Scaffold, Cannabinoid receptor, Stereochemistry, medicine.medical_treatment, Cell Line, Models, Drug Discovery, Cannabinoid receptor type 2, medicine, Receptor, Tumor, Chemistry, Synthetic, Rational design, Molecular, Chemistry Techniques, General Medicine, Anti proliferative, CB1, Settore CHIM/08 - Chimica Farmaceutica, CB2, Cell culture, lipids (amino acids, peptides, and proteins)

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::792b5ba1fa57da3022f3c3fd743f9b0eTest
http://hdl.handle.net/11588/830241Test

المؤلفون: Chiara Laezza, Patrizia Gazzerro, Maurizio Bifulco, Giuseppina Gangemi, Elena Ciaglia, Anna Maria Malfitano

المساهمون: Malfitano, A. M., Ciaglia, E., Gangemi, G., Gazzerro, P., Laezza, C., Bifulco, M.

المصدر: Expert opinion on therapeutic patents 15 (2011): 297–308.
info:cnr-pdr/source/autori:Malfitano AM, Ciaglia E, Gangemi G, Gazzerro P, Laezza C, Bifulco M./titolo:Update on the endocannabinoid system as an anticancer target./doi:/rivista:Expert opinion on therapeutic patents/anno:2011/pagina_da:297/pagina_a:308/intervallo_pagine:297–308/volume:15

مصطلحات موضوعية: Cannabinoid receptor, Endocannabinoid system, medicine.medical_treatment, Clinical Biochemistry, Antineoplastic Agents, Pharmacology, Biology, Antineoplastic Agent, Receptor, Cannabinoid, CB2, Drug Delivery Systems, Receptor, Cannabinoid, CB1, Neoplasms, Cannabinoid Receptor Modulators, Drug Discovery, medicine, Cannabinoid receptor type 2, Animals, Humans, Receptor, Cancer, Endocannabinoid, Animal, medicine.disease, Cannabinoid Receptor Modulator, Drug Design, Cancer cell, Cancer research, Neoplasm, Molecular Medicine, lipids (amino acids, peptides, and proteins), Cannabinoid, Signal transduction, Drug Delivery System, Human, Signal Transduction, Endocannabinoids

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20036669d62b7e8a15807ad8bde88356Test
http://hdl.handle.net/11386/3040452Test

المؤلفون: Anna Maria Malfitano, Chiara Laezza, Tiziana Di Matola, Paolo Ricchi, Maurizio Bifulco

المساهمون: Laezza, C, Malfitano, Am, Di Matola, T, Ricchi, P, Bifulco, M.

المصدر: Molecular carcinogenesis
49 (2010): 892–901.
info:cnr-pdr/source/autori:Laezza C; Malfitano AM; Di Matola T; Ricchi P; Bifulco M./titolo:Involvement of Akt%2FNF-ºB pathway in N6-isopentenyladenosine-induced apoptosis in human breast cancer cells./doi:/rivista:Molecular carcinogenesis (Print)/anno:2010/pagina_da:892/pagina_a:901/intervallo_pagine:892–901/volume:49

مصطلحات موضوعية: Cancer Research, Cyclin E, Cell Survival, Antineoplastic Agents, Apoptosis, Breast Neoplasms, Biology, Isopentenyladenosine, Cyclin D1, Cell Line, Tumor, Humans, Molecular Biology, Protein kinase B, PI3K/AKT/mTOR pathway, Cell Proliferation, bcl-2-Associated X Protein, Cell Nucleus, Cell growth, Caspase 3, Cell Cycle, Cyclin-Dependent Kinase 2, NF-kappa B, Cytochromes c, Cell biology, Cancer cell, Cancer research, Female, Signal transduction, N(6)-isopentenyladenosine, NF-kappa B pathway, apoptosis, Proto-Oncogene Proteins c-akt, Signal Transduction

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c6834d9a3a499c59e4216345fa16a07Test
https://publications.cnr.it/doc/21320Test

المؤلفون: Simona Pisanti, Mario Vitale, Chiara Laezza, Maurizio Bifulco, Michele Caraglia, Patrizia Gazzerro, Laura Fiorentino, Giuseppe Portella

المساهمون: Laezza, C, Fiorentino, L, Pisanti, S, Gazzerro, P, Caraglia, Michele, Portella, G, Vitale, M, Bifulco, M., Caraglia, M, Portella, Giuseppe, Vitale, Mario

المصدر: Journal of molecular medicine (Berl., Print) 86 (2008): 1341–1351.
info:cnr-pdr/source/autori:Laezza C; Fiorentino L; Pisanti S; Gazzerro P; Caraglia M; Portella G; Vitale M; Bifulco M/titolo:Lovastatin induces apoptosis of k-ras-transformed thyroid cells via inhibition of ras farnesylation and by modulating redox state./doi:/rivista:Journal of molecular medicine (Berl., Print)/anno:2008/pagina_da:1341/pagina_a:1351/intervallo_pagine:1341–1351/volume:86

مصطلحات موضوعية: MAPK/ERK pathway, Male, Programmed cell death, p38 mitogen-activated protein kinases, Thyroid Gland, Mice, Nude, lovastatin, Antineoplastic Agents, Apoptosis, Biology, medicine.disease_cause, Cell Line, thyroid, Mice, Drug Discovery, medicine, Animals, Protein kinase A, Genetics (clinical), Prenylation, Kinase, Cell Cycle, apoptosi, Cell biology, Rats, Cell Transformation, Neoplastic, Genes, ras, Biochemistry, Molecular Medicine, Female, Lovastatin, Carcinogenesis, Reactive Oxygen Species, medicine.drug, Signal Transduction

وصف الملف: STAMPA

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc9e7416ee9bd745bc061465fc310d94Test
http://hdl.handle.net/11591/185931Test