المؤلفون: Musisi, Emmanuel, Dide-Agossou, Christian, Mubarak, Reem Al, Rossmassler, Karen, Ssesolo, Abdul Wahab, Kaswabuli, Sylvia, Byanyima, Patrick, Sanyu, Ingvar, Zawedde, Josephine, Worodria, William, Voskuil, Martin I, Savic, Rada M, Nahid, Payam, Davis, J Lucian, Huang, Laurence, Moore, Camille M, Walter, Nicholas D

المصدر: Microbiology Spectrum. 9(2)

مصطلحات موضوعية: Infectious Diseases, Orphan Drug, Lung, Clinical Research, Emerging Infectious Diseases, Antimicrobial Resistance, Tuberculosis, HIV/AIDS, Rare Diseases, Infection, Good Health and Well Being, Adult, Biomarkers, Female, Humans, Male, Mycobacterium tuberculosis, RNA, Bacterial, RNA, Ribosomal, Sputum, Tuberculosis, Pulmonary, human, sputum, assay development, pharmacodynamics

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/5q5654f0Test

المؤلفون: Ernest, Jacqueline P, Strydom, Natasha, Wang, Qianwen, Zhang, Nan, Nuermberger, Eric, Dartois, Véronique, Savic, Rada M

المصدر: The Annual Review of Pharmacology and Toxicology. 61(1)

مصطلحات موضوعية: Tuberculosis, Infectious Diseases, Vaccine Related, Emerging Infectious Diseases, Antimicrobial Resistance, Prevention, Biodefense, Orphan Drug, HIV/AIDS, Rare Diseases, Evaluation of treatments and therapeutic interventions, Development of treatments and therapeutic interventions, 5.9 Resources and infrastructure (treatment development), 5.1 Pharmaceuticals, 6.1 Pharmaceuticals, Infection, Good Health and Well Being, Antitubercular Agents, Drug Combinations, Humans, Tuberculosis, Multidrug-Resistant, pharmacokinetics-pharmacodynamics, drug development, tuberculosis, antituberculosis agents, translational science, modeling, simulation, Biological Sciences, Medical and Health Sciences, Pharmacology & Pharmacy

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/7nb0x802Test

المؤلفون: Zhang, Nan, Strydom, Natasha, Tyagi, Sandeep, Soni, Heena, Tasneen, Rokeya, Nuermberger, Eric L, Savic, Rada M

المصدر: Antimicrobial Agents and Chemotherapy. 64(3)

مصطلحات موضوعية: Prevention, Orphan Drug, Tuberculosis Vaccine, Infectious Diseases, Vaccine Related, Immunization, Tuberculosis, Emerging Infectious Diseases, Rare Diseases, Antimicrobial Resistance, Biotechnology, Biodefense, 3.4 Vaccines, 6.1 Pharmaceuticals, 5.1 Pharmaceuticals, Prevention of disease and conditions, and promotion of well-being, Evaluation of treatments and therapeutic interventions, Development of treatments and therapeutic interventions, Infection, Good Health and Well Being, Adaptive Immunity, Animals, Antitubercular Agents, Bacterial Load, Disease Models, Animal, Female, Host-Pathogen Interactions, Immunogenicity, Vaccine, Isoniazid, Lung, Mice, Mice, Inbred BALB C, Mice, Nude, Mycobacterium tuberculosis, Pyrazinamide, Recurrence, Rifampin, Tuberculosis Vaccines, TB disease, mouse model, mechanistic modeling, adaptive immunity, drug discovery and development, vaccine, pyrazinamide, Microbiology, Medical Microbiology, Pharmacology and Pharmaceutical Sciences

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/8vj3v30wTest

المؤلفون: Denti, Paolo, Garcia-Prats, Anthony J, Draper, Heather R, Wiesner, Lubbe, Winckler, Jana, Thee, Stephanie, Dooley, Kelly E, Savic, Rada M, McIlleron, Helen M, Schaaf, H Simon, Hesseling, Anneke C

المصدر: Antimicrobial Agents and Chemotherapy. 62(2)

مصطلحات موضوعية: Medical Microbiology, Biomedical and Clinical Sciences, Infectious Diseases, Emerging Infectious Diseases, Clinical Trials and Supportive Activities, Antimicrobial Resistance, Tuberculosis, HIV/AIDS, Clinical Research, Pediatric, Rare Diseases, Pediatric Research Initiative, Orphan Drug, Prevention, 6.1 Pharmaceuticals, Evaluation of treatments and therapeutic interventions, Infection, Good Health and Well Being, Anti-HIV Agents, Antiretroviral Therapy, Highly Active, Antitubercular Agents, Area Under Curve, Child, Child, Preschool, Coinfection, Drug Administration Schedule, Drug Dosage Calculations, Female, HIV, HIV Infections, Humans, Infant, Levofloxacin, Male, Models, Statistical, Mycobacterium tuberculosis, Prospective Studies, South Africa, Tablets, Tuberculosis, Multidrug-Resistant, NONMEM, allometric scaling, dosing recommendations, fluoroquinolones, maturation, pediatric, population PK modeling, Microbiology, Pharmacology and Pharmaceutical Sciences, Medical microbiology, Pharmacology and pharmaceutical sciences

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/1w32j082Test

المؤلفون: Karen Rossmassler, Nicholas D. Walter, Martin I. Voskuil, Abdul Wahab Ssesolo, Patrick Byanyima, Rada M. Savic, Sylvia Kaswabuli, Josephine Zawedde, J. Lucian Davis, Payam Nahid, Reem Al Mubarak, William Worodria, Christian Dide-Agossou, Ingvar Sanyu, Emmanuel Musisi, Camille M. Moore, Laurence Huang

المساهمون: University of St Andrews. School of Medicine, University of St Andrews. Infection and Global Health Division, Lainhart, William

المصدر: Microbiology spectrum, vol 9, iss 2
Microbiology Spectrum, Vol 9, Iss 2 (2021)
Microbiology Spectrum

مصطلحات موضوعية: Male, Drug trial, assay development, Physiology, QH301 Biology, Lung, Ecology, biology, Bacterial, Pulmonary, QR1-502, RNA, Bacterial, Infectious Diseases, HIV/AIDS, Female, medicine.symptom, Infection, Research Article, Adult, Microbiology (medical), RM, Tuberculosis, RRNA synthesis, Microbiology, Mycobacterium tuberculosis, QH301, Rare Diseases, SDG 3 - Good Health and Well-being, Clinical Research, Genetics, medicine, pharmacodynamics, Humans, human, Pharmacodynamic monitoring, Tuberculosis, Pulmonary, Ribosomal, General Immunology and Microbiology, business.industry, sputum, DAS, Cell Biology, NIS, Ribosomal RNA, medicine.disease, biology.organism_classification, RM Therapeutics. Pharmacology, Good Health and Well Being, Emerging Infectious Diseases, Orphan Drug, RNA, Ribosomal, Pharmacodynamics, Immunology, RNA, Sputum, Antimicrobial Resistance, business, Biomarkers

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26d5f248c1f0a49d6cecfac372ca1a64Test
https://escholarship.org/uc/item/5q5654f0Test

المؤلفون: Qianwen Wang, Véronique Dartois, Rada M. Savic, Natasha Strydom, Eric L. Nuermberger, Jacqueline P Ernest, Nan Zhang

المصدر: Annu Rev Pharmacol Toxicol
Annual review of pharmacology and toxicology, vol 61, iss 1

مصطلحات موضوعية: 0301 basic medicine, Antitubercular Agents, Toxicology, Bioinformatics, Medical and Health Sciences, Tuberculosis, Multidrug-Resistant, Pharmacology & Pharmacy, media_common, Multidrug-Resistant, Biological Sciences, simulation, Drug Combinations, Infectious Diseases, Drug development, 5.1 Pharmaceuticals, 6.1 Pharmaceuticals, HIV/AIDS, Development of treatments and therapeutic interventions, Translational science, Infection, Drug, Tuberculosis, translational science, media_common.quotation_subject, 030106 microbiology, Article, Vaccine Related, 03 medical and health sciences, Rare Diseases, Disease severity, Biodefense, medicine, Humans, pharmacokinetics-pharmacodynamics, Pharmacology, business.industry, Prevention, antituberculosis agents, Evaluation of treatments and therapeutic interventions, modeling, medicine.disease, drug development, 5.9 Resources and infrastructure (treatment development), Multiple drug resistance, Regimen, Emerging Infectious Diseases, Orphan Drug, Good Health and Well Being, 030104 developmental biology, Infectious disease (medical specialty), Antimicrobial Resistance, business

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c00850ba23c276bca7ed3827e9bdda94Test
https://pubmed.ncbi.nlm.nih.gov/32806997Test

المؤلفون: Eric L. Nuermberger, Heena Soni, Natasha Strydom, Nan Zhang, Rokeya Tasneen, Rada M. Savic, Sandeep Tyagi

المصدر: Antimicrobial Agents and Chemotherapy
Antimicrobial agents and chemotherapy, vol 64, iss 3

مصطلحات موضوعية: and promotion of well-being, Nude, Antitubercular Agents, Adaptive Immunity, drug discovery and development, Efficacy, Mice, Tuberculosis Vaccine, Immunogenicity, Vaccine, Recurrence, vaccine, Pharmacology (medical), Tuberculosis Vaccines, Lung, Inbred BALB C, media_common, Mice, Inbred BALB C, 0303 health sciences, biology, Pharmacology and Pharmaceutical Sciences, Acquired immune system, Immunogenicity, mechanistic modeling, 3. Good health, Infectious Diseases, 3.4 Vaccines, 5.1 Pharmaceuticals, Medical Microbiology, 6.1 Pharmaceuticals, Host-Pathogen Interactions, Female, Development of treatments and therapeutic interventions, Rifampin, Infection, Biotechnology, medicine.drug, Drug, pyrazinamide, Tuberculosis, mouse model, media_common.quotation_subject, Mice, Nude, Microbiology, Vaccine Related, Mycobacterium tuberculosis, 03 medical and health sciences, Rare Diseases, Immune system, Biodefense, Isoniazid, medicine, Animals, Experimental Therapeutics, 030304 developmental biology, Pharmacology, Animal, 030306 microbiology, business.industry, Prevention, Evaluation of treatments and therapeutic interventions, biochemical phenomena, metabolism, and nutrition, Pyrazinamide, Prevention of disease and conditions, Editor's Pick, medicine.disease, biology.organism_classification, Vaccine efficacy, TB disease, Bacterial Load, Disease Models, Animal, Good Health and Well Being, Emerging Infectious Diseases, Orphan Drug, Disease Models, Immunology, bacteria, Immunization, Antimicrobial Resistance, business

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70d8fb5222a39d8667d2e25174a13225Test
https://doi.org/10.1128/aac.01727-19Test

المؤلفون: Anneke C. Hesseling, Jana Winckler, Rada M. Savic, Helen McIlleron, Kelly E. Dooley, Paolo Denti, Heather Draper, Stephanie Thee, Lubbe Wiesner, H. Simon Schaaf, Anthony J. Garcia-Prats

المصدر: Antimicrobial agents and chemotherapy, vol 62, iss 2

مصطلحات موضوعية: 0301 basic medicine, Male, Pediatrics, Antitubercular Agents, dosing recommendations, HIV Infections, Levofloxacin, Pharmacology, South Africa, 0302 clinical medicine, Models, Antiretroviral Therapy, Highly Active, Tuberculosis, Multidrug-Resistant, Medicine, Pharmacology (medical), Drug Dosage Calculations, 030212 general & internal medicine, Prospective Studies, fluoroquinolones, Child, NONMEM, Pediatric, Coinfection, Pharmacology and Pharmaceutical Sciences, Multidrug-Resistant, Statistical, Infectious Diseases, Medical Microbiology, 6.1 Pharmaceuticals, Area Under Curve, Child, Preschool, HIV/AIDS, Female, Infection, allometric scaling, medicine.drug, Tablets, medicine.medical_specialty, Pediatric Research Initiative, Tuberculosis, Anti-HIV Agents, 030106 microbiology, Clinical Trials and Supportive Activities, Antiretroviral Therapy, Population pharmacokinetics, Microbiology, Drug Administration Schedule, 03 medical and health sciences, Rare Diseases, Pharmacokinetics, Clinical Research, Humans, Highly Active, Dosing, Preschool, Models, Statistical, business.industry, maturation, Prevention, Evaluation of treatments and therapeutic interventions, HIV, Infant, Mycobacterium tuberculosis, medicine.disease, Multiple drug resistance, population PK modeling, Emerging Infectious Diseases, Orphan Drug, Good Health and Well Being, Antimicrobial Resistance, business, Dose selection

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bdbc4d0cf3bad153e9c71c4073c8773cTest
https://pubmed.ncbi.nlm.nih.gov/29133560Test