دورية أكاديمية

Appropriate Use of Short-Course Antibiotics in Common Infections: Best Practice Advice From the American College of Physicians.

التفاصيل البيبلوغرافية
العنوان: Appropriate Use of Short-Course Antibiotics in Common Infections: Best Practice Advice From the American College of Physicians.
المؤلفون: Lee, Rachael A., Centor, Robert M., Humphrey, Linda L., Jokela, Janet A., Andrews, Rebecca, Qaseem, Amir, Scientific Medical Policy Committee of the American College of Physicians, Akl, Elie A., Bledsoe, Thomas A., Forciea, Mary Ann, Haeme, Ray, Kansagara, Devan L., Marcucci, Maura, Miller, Matthew C., Obley, Adam J.
المصدر: Annals of Internal Medicine; 6/15/2021, Vol. 174 Issue 6, p822-827, 6p, 1 Chart
مصطلحات موضوعية: URINARY tract infections, MEDICAL personnel, PHYSICIANS, OBSTRUCTIVE lung diseases, BEST practices, COMMUNITY-acquired pneumonia, PNEUMONIA, PYELONEPHRITIS, CYSTITIS, CELLULITIS, DRUG administration, BRONCHITIS, PRIMARY health care, COMMUNITY-acquired infections, BACTERIAL diseases, ANTIBIOTICS
مستخلص: Description: Antimicrobial overuse is a major health care issue that contributes to antibiotic resistance. Such overuse includes unnecessarily long durations of antibiotic therapy in patients with common bacterial infections, such as acute bronchitis with chronic obstructive pulmonary disease (COPD) exacerbation, community-acquired pneumonia (CAP), urinary tract infections (UTIs), and cellulitis. This article describes best practices for prescribing appropriate and short-duration antibiotic therapy for patients presenting with these infections.Methods: The authors conducted a narrative literature review of published clinical guidelines, systematic reviews, and individual studies that addressed bronchitis with COPD exacerbations, CAP, UTIs, and cellulitis. This article is based on the best available evidence but was not a formal systematic review. Guidance was prioritized to the highest available level of synthesized evidence.Best Practice Advice1: Clinicians should limit antibiotic treatment duration to 5 days when managing patients with COPD exacerbations and acute uncomplicated bronchitis who have clinical signs of a bacterial infection (presence of increased sputum purulence in addition to increased dyspnea, and/or increased sputum volume).Best Practice Advice2: Clinicians should prescribe antibiotics for community-acquired pneumonia for a minimum of 5 days. Extension of therapy after 5 days of antibiotics should be guided by validated measures of clinical stability, which include resolution of vital sign abnormalities, ability to eat, and normal mentation.Best Practice Advice3: In women with uncomplicated bacterial cystitis, clinicians should prescribe short-course antibiotics with either nitrofurantoin for 5 days, trimethoprim-sulfamethoxazole (TMP-SMZ) for 3 days, or fosfomycin as a single dose. In men and women with uncomplicated pyelonephritis, clinicians should prescribe short-course therapy either with fluoroquinolones (5 to 7 days) or TMP-SMZ (14 days) based on antibiotic susceptibility.Best Practice Advice4: In patients with nonpurulent cellulitis, clinicians should use a 5- to 6-day course of antibiotics active against streptococci, particularly for patients able to self-monitor and who have close follow-up with primary care. [ABSTRACT FROM AUTHOR]
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قاعدة البيانات: Complementary Index