دورية أكاديمية

Evaluation of a method for the determination of antibacterial activity of chitosan.

التفاصيل البيبلوغرافية
العنوان: Evaluation of a method for the determination of antibacterial activity of chitosan.
المؤلفون: Kulikov, S., Bayazitova, L., Tyupkina, O., Zelenikhin, P., Salnikova, M., Bezrodnykh, E., Tikhonov, V.
المصدر: Applied Biochemistry & Microbiology; Sep2016, Vol. 52 Issue 5, p502-507, 6p
مصطلحات موضوعية: CHITOSAN, ANTI-infective agents, MOLECULAR weights, SOLUBILITY, CHITIN
مستخلص: A method for the determination of the antimicrobial activity of chitosan with the use of organic salts for the production of pH in the range of 5.5-8.2 was studied. The double-dilution method demonstrated the effectiveness of the determination of the antimicrobial activity of chitosan samples with different molecular weights and solubilities. It was found that the antibacterial activity increased at low pH values with increasing molecular weight, but chitosans with a molecular weight of 5-6 kDa showed higher activity at neutral and slightly alkaline pH levels. Determination of the antimicrobial activity of various chitosan samples at different pH values allowed a more reliable assessment of the potential biological activity of chitosan. [ABSTRACT FROM AUTHOR]
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قاعدة البيانات: Complementary Index
الوصف
تدمد:00036838
DOI:10.1134/S0003683816050100