التفاصيل البيبلوغرافية
| العنوان: |
Exploring the prevalence, impact and experience of cardiac cachexia in patients with advanced heart failure and their caregivers: A sequential phased study. |
| المؤلفون: |
Carson, Matthew A, Reid, Joanne, Hill, Loreena, Dixon, Lana, Donnelly, Patrick, Slater, Paul, Hill, Alyson, Piper, Susan E, McDonagh, Theresa A, Fitzsimons, Donna |
| المصدر: |
Palliative Medicine; Jul2022, Vol. 36 Issue 7, p1118-1128, 11p |
| مصطلحات موضوعية: |
RESEARCH, ASSOCIATIONS, institutions, etc., C-reactive protein, CAREGIVERS, CROSS-sectional method, RESEARCH methodology, ANTHROPOMETRY, QUANTITATIVE research, INTERVIEWING, QUALITATIVE research, QUALITY of life, CACHEXIA, HEART failure |
| مصطلحات جغرافية: |
UNITED Kingdom |
| مستخلص: |
Background: Cardiac Cachexia is a wasting syndrome that has a significant impact on patient mortality and quality of life world-wide, although it is poorly understood in clinical practice. Aim: Identify the prevalence of cardiac cachexia in patients with advanced New York Heart Association (NYHA) functional class and explore its impact on patients and caregivers. Design: An exploratory cross-sectional study. The sequential approach had two phases, with phase 1 including 200 patients with NYHA III-IV heart failure assessed for characteristics of cardiac cachexia. Phase 2 focussed on semi-structured interviews with eight cachectic patients and five caregivers to ascertain the impact of the syndrome. Setting/participants: Two healthcare trusts within the United Kingdom. Results: Cardiac Cachexia was identified in 30 out of 200 participants, giving a prevalence rate of 15%. People with cachexia had a significantly reduced average weight and anthropometric measures (p < 0.05). Furthermore, individuals with cachexia experienced significantly more fatigue, had greater issues with diet and appetite, reduced physical wellbeing and overall reduced quality of life. C-reactive protein was significantly increased, whilst albumin and red blood cell count were significantly decreased in the cachectic group (p < 0.05). From qualitative data, four key themes were identified: (1) 'Changed relationship with food and eating', (2) 'Not me in the mirror', (3) 'Lack of understanding regarding cachexia' and (4) 'Uncertainty regarding the future'. Conclusions: Cardiac cachexia has a debilitating effect on patients and caregivers. Future work should focus on establishing a specific definition and clinical pathway to enhance patient and caregiver support. [ABSTRACT FROM AUTHOR] |
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| قاعدة البيانات: |
Complementary Index |
