التفاصيل البيبلوغرافية
| العنوان: |
Antioxidant Status, Antidiabetic Properties and Effects on Caco-2 Cells of Colored and Non-Colored Enriched Extracts of Sweet Cherry Fruits. |
| المؤلفون: |
Gonçalves, Ana C., Rodrigues, Márcio, Santos, Adriana O., Alves, Gilberto, Silva, Luís R. |
| المصدر: |
Nutrients; Nov2018, Vol. 10 Issue 11, p1688, 1p |
| مستخلص: |
This study aimed to compare three different extracts of Saco sweet cherry, namely the non-colored fraction, colored fraction, and total extract concerning phenolic composition, antioxidant and antidiabetic potential, and erythrocytes' protection and effects on Caco-2 cells. Twenty-two phenolic compounds were identified using high-performance liquid chromatography with diode-array detection. Hydroxycinnamic acids were the most predominant in both the non-colored fraction and total extract, while cyanidin-3-O-rutinoside was the main anthocyanin found in the colored fraction. The total extract was the most effective against 1,1-diphenyl-2-picrylhydrazyl, nitric oxide, and superoxide radicals, and in the inhibition of α-glucosidase enzyme. The colored fraction revealed the best activity against hemoglobin oxidation and hemolysis. Regarding to Caco-2 cells, the colored extract exhibited the highest cytotoxic effects, while the total extract was the most efficient in protecting these cells against oxidative damage induced by tert-butyl hydroperoxide. [ABSTRACT FROM AUTHOR] |
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| قاعدة البيانات: |
Complementary Index |
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