المؤلفون: Abernethie, A., Gastaldello, Annalisa, Maltese, G., Morgan, RM, McInnes, Kerry, Small, Gary R., Walker, Brian R., Livingstone, Dawn EW., Hadoke, P.W.F., Andrew, Ruth

المصدر: Abernethie , A , Gastaldello , A , Maltese , G , Morgan , RM , McInnes , K , Small , G R , Walker , B R , Livingstone , D EW , Hadoke , P W F & Andrew , R 2022 , ' Comparison of mechanisms of angiostasis caused by the anti-inflammatory steroid 5α-tetrahydrocorticosterone versus conventional glucocorticoids ' , European Journal of Pharmacology , vol. 929 , 175111 . https://doi.org/10.1016/j.ejphar.2022.175111Test

مصطلحات موضوعية: 5α-tetrahydrocorticosterone, Angiogenesis, Blood vessel, Glucocorticoids, Inflammation, Corticosterone/analogs & derivatives, Receptors, Glucocorticoid/metabolism, Hydrocortisone/pharmacology, Mice, Inbred C57BL, Neovascularization, Pathologic, Anti-Inflammatory Agents/pharmacology, Male, Glucocorticoids/pharmacology, Animals, Dexamethasone/pharmacology, Mifepristone/pharmacology

وصف الملف: application/pdf

العلاقة: https://pure.sruc.ac.uk/en/publications/de17dc4c-858a-4cdb-8f73-0bdfefc052ecTest

الإتاحة: https://doi.org/10.1016/j.ejphar.2022.175111Test
https://pure.sruc.ac.uk/en/publications/de17dc4c-858a-4cdb-8f73-0bdfefc052ecTest
https://pure.sruc.ac.uk/ws/files/48201772/Merged_Abernethie_for_PURE.pdfTest
https://pure.sruc.ac.uk/ws/files/48219077/1_s2.0_S0014299922003727_main.pdfTest
http://www.scopus.com/inward/record.url?scp=85133298909&partnerID=8YFLogxKTest

المؤلفون: Webster, Scott P, McBride, Andrew, Binnie, Margaret, Sooy, Karen, Seckl, Jonathan R, Andrew, Ruth, Pallin, T David, Hunt, Hazel J, Perrior, Trevor R, Ruffles, Vincent S, Ketelbey, J William, Boyd, Alan, Walker, Brian R

المصدر: British Journal of Pharmacology

مصطلحات موضوعية: Adult, Male, Adolescent, Hydrocortisone, Thiophenes, Rats, Sprague-Dawley, Inhibitory Concentration 50, Young Adult, Dogs, Double-Blind Method, 11-beta-Hydroxysteroid Dehydrogenase Type 1, Animals, Humans, Tissue Distribution, Enzyme Inhibitors, Tetrahydrocortisol, Dose-Response Relationship, Drug, Brain, Middle Aged, Research Papers, Rats, Tetrahydrocortisone, Female, hormones, hormone substitutes, and hormone antagonists, Research Paper, Half-Life, Tropanes

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=pmid________::307946c131c5394bb4a29f7d05606ca7Test
http://europepmc.org/articles/PMC5301048Test

المؤلفون: White, Christopher I., Jansen, Maurits A., McGregor, Kieran, Mylonas, Katie J., Richardson, Rachel V., Thomson, Adrian, Moran, Carmel M., Seckl, Jonathan R., Walker, Brian R., Chapman, Karen E., Gray, Gillian A.

المصدر: Endocrinology

مصطلحات موضوعية: Heart Failure, Male, Mice, Knockout, Heart Ventricles, Renal-Cardiac-Vascular, Myocardial Infarction, Neovascularization, Physiologic, Cardiomegaly, Mice, Transgenic, Pulmonary Edema, Stroke Volume, Organ Size, Muscle, Smooth, Vascular, Mice, Inbred C57BL, Gene Expression Regulation, Coronary Circulation, 11-beta-Hydroxysteroid Dehydrogenase Type 1, Animals, Myocytes, Cardiac, hormones, hormone substitutes, and hormone antagonists, Crosses, Genetic, Original Research

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=pmid________::19a6dc0ce49e39146d7e5cf6d4a23f8aTest
http://europepmc.org/articles/PMC4701896Test

المؤلفون: Sooy, Karen, Noble, June, McBride, Andrew, Binnie, Margaret, Yau, Joyce L. W., Seckl, Jonathan R., Walker, Brian R., Webster, Scott P.

المصدر: Endocrinology
Sooy, K, Noble, J, McBride, A, Binnie, M, Yau, J L W, Seckl, J R, Walker, B R & Webster, S P 2015, ' Cognitive and disease-modifying effects of 11ß-hydroxysteroid dehydrogenase type 1 inhibition in male Tg2576 mice, a model of Alzheimer's disease ', Endocrinology . https://doi.org/10.1210/en.2015-1395Test

مصطلحات موضوعية: Cerebral Cortex, Amyloid beta-Peptides, Behavior, Animal, Mice, Transgenic, Plaque, Amyloid, Thiophenes, Insulysin, Mice, Inbred C57BL, Amyloid beta-Protein Precursor, Disease Models, Animal, Mice, Cognition, Alzheimer Disease, Memory, 11-beta-Hydroxysteroid Dehydrogenase Type 1, Animals, Humans, Pyrazoles, Maze Learning, Glucocorticoids-CRH-ACTH-Adrenal, hormones, hormone substitutes, and hormone antagonists, Original Research

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::16c04319bd8a86aa19b59cb4708de24bTest
http://europepmc.org/articles/PMC4655221Test

المؤلفون: Livingstone, Dawn E W, Di Rollo, Emma M, Mak, Tracy C-S, Sooy, Karen, Walker, Brian R, Andrew, Ruth

المصدر: Livingstone, D E W, Di Rollo, E M, Mak, T C-S, Sooy, K, Walker, B R & Andrew, R 2017, ' Metabolic dysfunction in female mice with disruption of 5α-reductase 1 ', Journal of Endocrinology, vol. 232, no. 1, pp. 29-36 . https://doi.org/10.1530/JOE-16-0125Test
The Journal of Endocrinology

مصطلحات موضوعية: obesity, Cholestenone 5 alpha-Reductase, Hypothalamo-Hypophyseal System, Research, Hypothalamus, Pituitary-Adrenal System, Mice, Transgenic, Diet, High-Fat, steroid metabolising hormones, Mice, Receptors, Glucocorticoid, Liver, Stress, Physiological, Animals, glucocorticoid, Female, Insulin Resistance, Corticosterone, Energy Metabolism, metabolism

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::c2d6cfda69fff1f290c53e4338199717Test
https://www.pure.ed.ac.uk/ws/files/29499804/29.full.pdfTest

المؤلفون: Livingstone, Dawn E W, Di Rollo, Emma M, Yang, Chenjing, Codrington, Lucy E, Mathews, John, Kara, Madina, Hughes, Katherine A, Kenyon, Christopher J, Walker, Brian R, Andrew, Ruth

المصدر: Livingstone , D E W , Di Rollo , E M , Yang , C , Codrington , L E , Mathews , J , Kara , M , Hughes , K A , Kenyon , C J , Walker , B R & Andrew , R 2014 , ' Relative adrenal insufficiency in mice deficient in 5α-reductase 1 ' , Journal of Endocrinology , vol. 222 , no. 2 , pp. 257-66 . https://doi.org/10.1530/JOE-13-0563Test

مصطلحات موضوعية: 3-Oxo-5-alpha-Steroid 4-Dehydrogenase, 5-alpha Reductase Inhibitors, Adrenal Insufficiency, Adrenocorticotropic Hormone, Animals, Corticosterone, Dexamethasone, Hypothalamo-Hypophyseal System, Male, Membrane Proteins, Mice, Knockout, Pituitary-Adrenal System, Stress, Psychological, Journal Article, Research Support, Non-U.S. Gov't

العلاقة: https://research-information.bris.ac.uk/en/publications/63267f9a-b45c-494a-87bb-78eabc48f82cTest

الإتاحة: https://doi.org/10.1530/JOE-13-0563Test
https://hdl.handle.net/1983/63267f9a-b45c-494a-87bb-78eabc48f82cTest
https://research-information.bris.ac.uk/en/publications/63267f9a-b45c-494a-87bb-78eabc48f82cTest

المؤلفون: McNeilly, Alison D, Macfarlane, David P, O'Flaherty, Emmett, Livingstone, Dawn E, Mitić, Tijana, McConnell, Kirsty M, McKenzie, Scott M, Davies, Eleanor, Reynolds, Rebecca M, Thiesson, Helle C, Skøtt, Ole, Walker, Brian R, Andrew, Ruth

المصدر: McNeilly , A D , Macfarlane , D P , O'Flaherty , E , Livingstone , D E , Mitić , T , McConnell , K M , McKenzie , S M , Davies , E , Reynolds , R M , Thiesson , H C , Skøtt , O , Walker , B R & Andrew , R 2010 , ' Bile acids modulate glucocorticoid metabolism and the hypothalamic-pituitary-adrenal axis in obstructive jaundice ' , Journal of Hepatology , vol. 52 , no. 5 , pp. 705-11 . https://doi.org/10.1016/j.jhep.2009.10.037Test

مصطلحات موضوعية: 3-Hydroxysteroid Dehydrogenases, Animals, Base Sequence, Bile Acids and Salts, Bile Ducts, Cytosol, Female, Glucocorticoids, Humans, Hydrocortisone, Hypothalamo-Hypophyseal System, Jaundice, Obstructive, Kinetics, Ligation, Liver, Male, Pituitary-Adrenal System, Promoter Regions, Genetic, Rats, Wistar, Tetrahydrocortisol, Transcription

العلاقة: https://portal.findresearcher.sdu.dk/da/publications/6d8453ee-f01b-4376-ab8c-16ccf17bd0aeTest

الإتاحة: https://doi.org/10.1016/j.jhep.2009.10.037Test
https://portal.findresearcher.sdu.dk/da/publications/6d8453ee-f01b-4376-ab8c-16ccf17bd0aeTest

المؤلفون: Malavasi, Elise L.V., Kelly, Val, Nath, Nikita, Gambineri, Alessandra, Dakin, Rachel S., Pagotto, Uberto, Pasquali, Renato, Walker, Brian R., Chapman, Karen E.

مصطلحات موضوعية: Adult, Adolescent, Base Sequence, CHO Cells, Middle Aged, Polymorphism, Single Nucleotide, Article, Gene Expression Regulation, Enzymologic, Young Adult, Cricetulus, Cricetinae, Protein Biosynthesis, 11-beta-Hydroxysteroid Dehydrogenase Type 1, Animals, Humans, Female, Promoter Regions, Genetic, hormones, hormone substitutes, and hormone antagonists, Cells, Cultured, Polycystic Ovary Syndrome

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=pmid________::63669c6a7f74d627770386326b37dd6dTest
https://europepmc.org/articles/PMC3971150Test/

المؤلفون: Morgan, Ruth A., Keen, John A., Walker, Brian R., Hadoke, Patrick W. F.

المصدر: PLoS ONE; 9/29/2016, Vol. 11 Issue 9, p1-14, 14p

مصطلحات موضوعية: VASCULAR diseases, LAMINITIS, MEDICAL economics, ENDOTHELIAL cells, VASOCONSTRICTORS, PHENYLEPHRINE

المؤلفون: Hadoke, Patrick W. F., Iqbal, Javaid, Walker, Brian R.

المصدر: British Journal of Pharmacology; Mar2009, Vol. 156 Issue 5, p689-712, 24p, 2 Diagrams, 3 Charts, 1 Graph

مصطلحات موضوعية: CARDIOVASCULAR diseases, GLUCOCORTICOID receptors, ANTI-inflammatory agents, ADRENOCORTICAL hormones, BIOCHEMISTRY, THERAPEUTIC use of glucocorticoids, HEART metabolism, GLUCOCORTICOIDS, BLOOD vessels, SMOOTH muscle, CELL receptors, ATHEROSCLEROSIS, IMMUNITY, OXIDOREDUCTASES, ANIMALS, CHEMICAL inhibitors