المؤلفون: Nielsen, Sebastian R, Strøbech, Jan E, Horton, Edward R, Jackstadt, Rene, Laitala, Anu, Bravo, Marina C, Maltese, Giorgia, Jensen, Adina RD, Reuten, Raphael, Rafaeva, Maria, Karim, Saadia A, Hwang, Chang-Il, Arnes, Luis, Tuveson, David A, Sansom, Owen J, Morton, Jennifer P, Erler, Janine T

المصدر: Nature Communications. 12(1)

مصطلحات موضوعية: Cancer, Rare Diseases, Digestive Diseases, Pancreatic Cancer, 5.1 Pharmaceuticals, Aetiology, 2.1 Biological and endogenous factors, Development of treatments and therapeutic interventions, Aminopyridines, Animals, Antineoplastic Combined Chemotherapy Protocols, CD8-Positive T-Lymphocytes, Carcinoma, Pancreatic Ductal, Cell Line, Tumor, Disease Models, Animal, Drug Synergism, Female, Humans, Immune Checkpoint Inhibitors, Lactams, Lactams, Macrocyclic, Lymphocyte Activation, Lymphocytes, Tumor-Infiltrating, Male, Mice, Mice, Transgenic, Neutrophils, Pancreatic Neoplasms, Programmed Cell Death 1 Receptor, Pyrazoles, Tumor Microenvironment

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/2g5382r1Test

المؤلفون: Azkanaz, Maria, Corominas-Murtra, Bernat, Ellenbroek, Saskia IJ, Bruens, Lotte, Webb, Anna T, Laskaris, Dimitrios, Oost, Koen C, Lafirenze, Simona JA, Annusver, Karl, Messal, Hendrik A, Iqbal, Sharif, Flanagan, Dustin J, Huels, David J, Rojas-Rodríguez, Felipe, Vizoso, Miguel, Kasper, Maria, Sansom, Owen J, Snippert, Hugo J, Liberali, Prisca, Simons, Benjamin D, Katajisto, Pekka, Hannezo, Edouard, van Rheenen, Jacco

مصطلحات موضوعية: Animals, Cell Count, Cell Movement, Intestinal Mucosa, Intestine, Small, Intestines, Mice, Receptors, G-Protein-Coupled, Stem Cells, Wnt Proteins

وصف الملف: Print-Electronic; application/pdf

العلاقة: https://www.repository.cam.ac.uk/handle/1810/346215Test

الإتاحة: https://doi.org/10.17863/CAM.93635Test
https://www.repository.cam.ac.uk/handle/1810/346215Test

المؤلفون: Knight, John Rp, Vlahov, Nikola, Gay, David M, Ridgway, Rachel A, Faller, William James, Proud, Christopher, Mallucci, Giovanna R, von der Haar, Tobias, Smales, Christopher Mark, Willis, Anne E, Sansom, Owen J

المصدر: nlmid: 101579614 ; essn: 2050-084X

مصطلحات موضوعية: RPL24, cancer biology, cell biology, eEF2K, in vivo models, intestinal cancer, mouse, protein sythesis, translation, Animals, Colorectal Neoplasms, Disease Models, Animal, Elongation Factor 2 Kinase, Female, Male, Mice, Transgenic, Mutation, Phosphorylation, Ribosomal Proteins, Signal Transduction

وصف الملف: application/pdf

العلاقة: https://www.repository.cam.ac.uk/handle/1810/333113Test

الإتاحة: https://doi.org/10.17863/CAM.80536Test
https://www.repository.cam.ac.uk/handle/1810/333113Test

المؤلفون: Parker, Christopher, Chambers, Adam C, Flanagan, Dustin J, Ho, Jasmine Wing Yu, Collard, Tracey J, Ngo, Greg, Baird, Duncan M, Timms, Penny, Morgan, Rhys G., Sansom, Owen J, Williams, Ann C

المصدر: Parker , C , Chambers , A C , Flanagan , D J , Ho , J W Y , Collard , T J , Ngo , G , Baird , D M , Timms , P , Morgan , R G , Sansom , O J & Williams , A C 2022 , ' BCL-3 loss sensitises colorectal cancer cells to DNA damage by targeting homologous recombination ' , DNA repair , vol. 115 , 103331 . https://doi.org/10.1016Test/j.dnarep.2022.103331

مصطلحات موضوعية: Animals, Cell Line, Tumor, Cisplatin/therapeutic use, Colorectal Neoplasms/drug therapy, DNA Damage, Homologous Recombination, Humans, Mice

وصف الملف: application/pdf

الإتاحة: https://doi.org/10.1016Test/j.dnarep.2022.103331
https://hdl.handle.net/1983/a562c74f-57b8-47be-b70e-d9e1984cfa3dTest
https://research-information.bris.ac.uk/en/publications/a562c74f-57b8-47be-b70e-d9e1984cfa3dTest
https://research-information.bris.ac.uk/ws/files/339239049/1_s2.0_S1568786422000647_main.pdfTest

المؤلفون: Topham, Caroline, Tighe, Anthony, Ly, Peter, Bennett, Ailsa, Sloss, Olivia, Nelson, Louisa, Ridgway, Rachel A, Huels, David, Littler, Samantha, Schandl, Claudia, Sun, Ying, Bechi, Beatrice, Procter, David J, Sansom, Owen J, Cleveland, Don W, Taylor, Stephen S

المصدر: Cancer Cell. 28(1)

مصطلحات موضوعية: Biochemistry and Cell Biology, Biomedical and Clinical Sciences, Oncology and Carcinogenesis, Biological Sciences, Cancer, Breast Cancer, Genetics, 2.1 Biological and endogenous factors, Aetiology, Generic health relevance, Animals, Antimitotic Agents, Apoptosis, Breast Neoplasms, Cell Line, Tumor, Colonic Neoplasms, Early Growth Response Protein 1, Female, Gene Expression Regulation, Neoplastic, Humans, Lung Neoplasms, Mice, Mitochondrial Membrane Transport Proteins, Mitosis, Molecular Sequence Data, Neoplasms, Ovarian Neoplasms, Paclitaxel, Proto-Oncogene Proteins c-bcl-2, Proto-Oncogene Proteins c-myc, bcl-X Protein, Neurosciences, Oncology & Carcinogenesis, Biochemistry and cell biology, Oncology and carcinogenesis

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/7423w4kdTest

المؤلفون: Knight, John R.P., Alexandrou, Constantinos, Skalka, George L., Vlahov, Nikola, Pennel, Kathryn, Officer, Leah, Teodosio, Ana, Kanellos, Georgios, Gay, David M., May-Wilson, Sebastian, Smith, Ewan M., Najumudeen, Arafath K., Gilroy, Kathryn, Ridgway, Rachel A., Flanagan, Dustin J., Smith, Rachael C.L., McDonald, Laura, MacKay, Craig, Cheasty, Anne, McArthur, Kerri, Stanway, Emma, Leach, Joshua D., Jackstadt, Rene, Waldron, Joseph A., Campbell, Andrew D., Vlachogiannis, Georgios, Valeri, Nicola, Haigis, Kevin M., Sonenberg, Nahum, Proud, Christopher G., Jones, Neil P., Swarbrick, Martin E., McKinnon, Heather J., Faller, William J., Quesne, John Le, Edwards, Joanne, Willis, Anne E., Bushell, Martin, Sansom, Owen J.

المصدر: Knight , J R P , Alexandrou , C , Skalka , G L , Vlahov , N , Pennel , K , Officer , L , Teodosio , A , Kanellos , G , Gay , D M , May-Wilson , S , Smith , E M , Najumudeen , A K , Gilroy , K , Ridgway , R A , Flanagan , D J , Smith , R C L , McDonald , L , MacKay , C , Cheasty , A , McArthur , K , Stanway , E , Leach , J D , ....

مصطلحات موضوعية: Animals, Colorectal Neoplasms/genetics, Disease Models, Animal, Eukaryotic Initiation Factor-4E/drug effects, Humans, Intracellular Signaling Peptides and Proteins/drug effects, MTOR Inhibitors/pharmacology, Mice, Inbred C57BL, Phosphorylation, Protein Serine-Threonine Kinases/drug effects, ResearchInstitutes_Networks_Beacons/mcrc, name=Manchester Cancer Research Centre

العلاقة: https://research.manchester.ac.uk/en/publications/e2b9afde-dfcb-40fe-b3a3-ece044a73148Test

الإتاحة: https://doi.org/10.1158/2159-8290.CD-20-0652Test
https://research.manchester.ac.uk/en/publications/e2b9afde-dfcb-40fe-b3a3-ece044a73148Test

المؤلفون: Grosso, Stefano, Marini, Alberto, Gyuraszova, Katarina, Voorde, Johan Vande, Sfakianos, Aristeidis, Garland, Gavin D, Tenor, Angela Rubio, Mordue, Ryan, Chernova, Tanya, Morone, Nobu, Sereno, Marco, Smith, Claire P, Officer, Leah, Farahmand, Pooyeh, Rooney, Claire, Sumpton, David, Das, Madhumita, Teodósio, Ana, Ficken, Catherine, Martin, Maria Guerra, Spriggs, Ruth V, Sun, Xiao-Ming, Bushell, Martin, Sansom, Owen J, Murphy, Daniel, MacFarlane, Marion, Le Quesne, John PC, Willis, Anne E

مصطلحات موضوعية: Animals, Asbestos, Humans, Mechanistic Target of Rapamycin Complex 1, Mechanistic Target of Rapamycin Complex 2, Mesothelioma, Malignant, Mice, Inbred C57BL, Knockout, Mitochondria, Naphthyridines, Oncogenes, Polyribosomes, Protein Biosynthesis, RNA, Messenger, Tumor Cells, Cultured

وصف الملف: Electronic; application/pdf

العلاقة: https://www.repository.cam.ac.uk/handle/1810/326930Test

الإتاحة: https://doi.org/10.17863/CAM.74379Test
https://www.repository.cam.ac.uk/handle/1810/326930Test

المؤلفون: Flanagan, Dustin J, Pentinmikko, Nalle, Luopajärvi, Kalle, Willis, Nicky J, Gilroy, Kathryn, Raven, Alexander P, Mcgarry, Lynn, Englund, Johanna I, Webb, Anna T, Scharaw, Sandra, Nasreddin, Nadia, Hodder, Michael C, Ridgway, Rachel A, Minnee, Emma, Sphyris, Nathalie, Gilchrist, Ella, Najumudeen, Arafath K, Romagnolo, Beatrice, Perret, Christine, Williams, Ann C, Clevers, Hans, Nummela, Pirjo, Lähde, Marianne, Alitalo, Kari, Hietakangas, Ville, Hedley, Ann, Clark, William, Nixon, Colin, Kirschner, Kristina, Jones, E Yvonne, Ristimäki, Ari, Leedham, Simon J, Fish, Paul V, Vincent, Jean-Paul, Katajisto, Pekka, Sansom, Owen J

المصدر: Flanagan , D J , Pentinmikko , N , Luopajärvi , K , Willis , N J , Gilroy , K , Raven , A P , Mcgarry , L , Englund , J I , Webb , A T , Scharaw , S , Nasreddin , N , Hodder , M C , Ridgway , R A , Minnee , E , Sphyris , N , Gilchrist , E , Najumudeen , A K , Romagnolo , B , Perret , C , Williams , A C , Clevers , H , Nummela , P , Lähde , ....

مصطلحات موضوعية: Adenoma/genetics, Adenomatous Polyposis Coli Protein/genetics, Animals, Cell Competition/genetics, Cell Differentiation, Cell Proliferation, Cell Transformation, Neoplastic/genetics, Colorectal Neoplasms/genetics, Culture Media, Conditioned, Disease Progression, Esterases/antagonists & inhibitors, Female, Genes, APC, Humans, Ligands, Male, Mice, Inbred C57BL, Mutation, Organoids/cytology, Stem Cells/cytology, Wnt Proteins/metabolism, Wnt Signaling Pathway

العلاقة: https://pure.knaw.nl/portal/en/publications/69a3582f-fc29-4f40-bc5f-17ba7825a11aTest

الإتاحة: https://doi.org/10.1038/s41586-021-03525-zTest
https://doi.org/20.500.11755/69a3582f-fc29-4f40-bc5f-17ba7825a11aTest
https://pure.knaw.nl/portal/en/publications/69a3582f-fc29-4f40-bc5f-17ba7825a11aTest
https://hdl.handle.net/20.500.11755/69a3582f-fc29-4f40-bc5f-17ba7825a11aTest

المؤلفون: Knight, John RP, Garland, Gavin, Pöyry, Tuija, Mead, Emma, Vlahov, Nikola, Sfakianos, Aristeidis, Grosso, Stefano, De-Lima-Hedayioglu, Fabio, Mallucci, Giovanna R, von der Haar, Tobias, Smales, C Mark, Sansom, Owen J, Willis, Anne E

مصطلحات موضوعية: Elongation control, Protein synthesis, mRNA translation control, Aminoacylation, Animals, Carcinogenesis, Disease, Health, Humans, Peptide Chain Elongation, Translational, RNA, Transfer

وصف الملف: Electronic; application/pdf

العلاقة: https://www.repository.cam.ac.uk/handle/1810/304820Test

الإتاحة: https://doi.org/10.17863/CAM.51902Test
https://www.repository.cam.ac.uk/handle/1810/304820Test

المؤلفون: Chong, Jean-Leon, Wenzel, Pamela L, Sáenz-Robles, M Teresa, Nair, Vivek, Ferrey, Antoney, Hagan, John P, Gomez, Yorman M, Sharma, Nidhi, Chen, Hui-Zi, Ouseph, Madhu, Wang, Shu-Huei, Trikha, Prashant, Culp, Brian, Mezache, Louise, Winton, Douglas J, Sansom, Owen J, Chen, Danian, Bremner, Rod, Cantalupo, Paul G, Robinson, Michael L, Pipas, James M, Leone, Gustavo

المصدر: Nature. 462(7275)

مصطلحات موضوعية: Biochemistry and Cell Biology, Biological Sciences, Stem Cell Research, Genetics, Stem Cell Research - Nonembryonic - Human, Stem Cell Research - Nonembryonic - Non-Human, 2.1 Biological and endogenous factors, Aetiology, 1.1 Normal biological development and functioning, Underpinning research, Alleles, Animals, Apoptosis, Cell Cycle, Cell Differentiation, Cell Proliferation, E2F Transcription Factors, E2F1 Transcription Factor, E2F2 Transcription Factor, E2F3 Transcription Factor, Embryo, Mammalian, Embryonic Stem Cells, Female, Gene Expression Regulation, Intestine, Small, Mice, Mice, Transgenic, Repressor Proteins, Retinoblastoma Protein, General Science & Technology

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/6n91b42hTest