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المصدر: Mol Ther
مصطلحات موضوعية: Male, Necrosis, Duchenne muscular dystrophy, Genetic Vectors, Degeneration (medical), Dystrophin, Mice, 03 medical and health sciences, 0302 clinical medicine, Genome editing, Drug Discovery, Genetics, medicine, Animals, Myocytes, Cardiac, Guide RNA, Muscle, Skeletal, Molecular Biology, 030304 developmental biology, Gene Editing, Pharmacology, 0303 health sciences, biology, Myocardium, Regeneration (biology), Skeletal muscle, Genetic Therapy, Dependovirus, Muscular Dystrophy, Animal, medicine.disease, Cell biology, Mice, Inbred C57BL, Muscular Dystrophy, Duchenne, Disease Models, Animal, medicine.anatomical_structure, 030220 oncology & carcinogenesis, Mutation, biology.protein, Molecular Medicine, Original Article, CRISPR-Cas Systems, medicine.symptom, RNA, Guide, Kinetoplastida
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::418b4b5a189776174b4dca1a60b402ffTest
https://doi.org/10.1016/j.ymthe.2020.11.003Test -
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المؤلفون: Jeffrey S. Chamberlain
المصدر: The New England journal of medicine. 386(12)
مصطلحات موضوعية: Muscular Dystrophy, Duchenne, Disease Models, Animal, Mice, Genetic Vectors, Animals, Humans, General Medicine, Genetic Therapy, Dependovirus, Infusions, Intravenous, Muscle, Skeletal
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37efa317126c99614bef105eb7fb8543Test
https://pubmed.ncbi.nlm.nih.gov/35320650Test -
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المؤلفون: Niclas E. Bengtsson, Julie M. Crudele, Jordan M. Klaiman, Christine L. Halbert, Stephen D. Hauschka, Jeffrey S. Chamberlain
المصدر: Mol Ther
مصطلحات موضوعية: Pharmacology, Gene Editing, Aging, Dystrophin, Muscular Dystrophy, Duchenne, Disease Models, Animal, Dogs, Drug Discovery, Genetics, Disease Progression, Molecular Medicine, Animals, Original Article, CRISPR-Cas Systems, Muscle, Skeletal, Molecular Biology
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f33fd42d19d0dd0ec239a07eb87d1d4Test
https://europepmc.org/articles/PMC9171147Test/ -
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المؤلفون: Linzie A. Wildenauer, Maxwell McCaughey, Andrea M. Spiker, Matthew A. Halanski, Connie S. Chamberlain, Ray Vanderby, Katie Henry, John A. Kink, Peiman Hematti
المصدر: Stem Cells (Dayton, Ohio)
مصطلحات موضوعية: 0301 basic medicine, Male, Stromal cell, exosomes, Biology, Regenerative Medicine, Exosome, Achilles Tendon, Cell therapy, 03 medical and health sciences, Rats, Nude, 0302 clinical medicine, medicine, Animals, Humans, Rats, Wistar, Macrophages, Mesenchymal stem cell, ligament healing, Mesenchymal Stem Cells, Cell Biology, M2 Macrophage, Microvesicles, Rats, 030104 developmental biology, medicine.anatomical_structure, Ligament, Cancer research, Molecular Medicine, Heterografts, Female, Stem cell, mesenchymal stromal cells, 030217 neurology & neurosurgery, Developmental Biology
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1afce3f8fc823a410909263e6aa6f20Test
http://europepmc.org/articles/PMC7821004Test -
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المؤلفون: Alexander A. Sousa, J. Keith Joung, Casey A. Maguire, Xandra O. Breakefield, Adrienn Volak, Niclas E. Bengtsson, David P. Corey, Martin Ingelsson, Bence György, Martin J. Aryee, Jeffrey S. Chamberlain, Sara P. Garcia, Alissa Muller, Stefan E. Spirig, Camilla Lööv, Benjamin P. Kleinstiver, Killian S. Hanlon, Mikołaj Piotr Zaborowski, Shengdar Q. Tsai
المصدر: Nature Communications, Vol 10, Iss 1, Pp 1-11 (2019)
Nature Communicationsمصطلحات موضوعية: 0301 basic medicine, CRISPR-Cas9 genome editing, Male, viruses, General Physics and Astronomy, Medical Biotechnology (with a focus on Cell Biology (including Stem Cell Biology), Molecular Biology, Microbiology, Biochemistry or Biopharmacy), Genome, Transduction (genetics), Mice, 0302 clinical medicine, CRISPR, Clustered Regularly Interspaced Short Palindromic Repeats, lcsh:Science, Gene Editing, Neurons, Multidisciplinary, Muscles, Brain, Chromosome Mapping, Dependovirus, Bacteriophage lambda, 3. Good health, Cochlea, Treatment Outcome, 030220 oncology & carcinogenesis, Dna breaks, Gene Targeting, Transgene, Virus Integration, Science, Genetic Vectors, Mice, Transgenic, Computational biology, Biology, General Biochemistry, Genetics and Molecular Biology, Virus, Article, Cell Line, Vector integration, 03 medical and health sciences, Animals, Humans, Medicinsk bioteknologi (med inriktning mot cellbiologi (inklusive stamcellsbiologi), molekylärbiologi, mikrobiologi, biokemi eller biofarmaci), DNA Breaks, General Chemistry, Genetic Therapy, Endonucleases, Mice, Inbred C57BL, Targeted gene repair, 030104 developmental biology, Cell culture, lcsh:Q, CRISPR-Cas Systems, Neuroscience
وصف الملف: application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb20ae11699351b7bf4e115cf53a116aTest
https://doaj.org/article/d463e02a3bdc40c4aca343f4b409877aTest -
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المؤلفون: Neha Rastogi, Lisa E. Dorn, Megan D. Gertzen, Jeovanna Lowe, Zachary M. Howard, Guy L. Odom, Jill A. Rafael-Fortney, Jeffrey S. Chamberlain, Federica Accornero, Pierce C. Ciccone
المصدر: JCI Insight, Vol 6, Iss 7 (2021)
JCI Insightمصطلحات موضوعية: 0301 basic medicine, Cardiac function curve, Male, musculoskeletal diseases, medicine.medical_specialty, congenital, hereditary, and neonatal diseases and abnormalities, Utrophin, Duchenne muscular dystrophy, Genetic enhancement, Cardiomyopathy, Cardiology, Inflammation, Mice, Transgenic, Mouse models, Dystrophin, 03 medical and health sciences, Electrocardiography, 0302 clinical medicine, Gene therapy, Fibrosis, Internal medicine, medicine, Animals, Humans, Heart Failure, Mice, Knockout, business.industry, General Medicine, Genetic Therapy, medicine.disease, Cardiovascular disease, Clinical trial, Mice, Inbred C57BL, Muscular Dystrophy, Duchenne, Disease Models, Animal, 030104 developmental biology, 030220 oncology & carcinogenesis, Heart failure, Medicine, Female, medicine.symptom, business, Cardiomyopathies, Research Article
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5b194e6e4ff3065281aa84d4f9b50d2Test
https://doaj.org/article/edf8afa3bfcf4133a3ecce62112683f8Test -
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المؤلفون: Jeffrey S. Chamberlain, Julie M. Crudele
المصدر: Hum Mol Genet
مصطلحات موضوعية: Invited Review Article, Genetic enhancement, Genetic Vectors, Biology, Bioinformatics, Myotonic dystrophy, Muscular Dystrophies, Viral vector, 03 medical and health sciences, 0302 clinical medicine, Transduction, Genetic, Genetics, medicine, Animals, Humans, Genetic Predisposition to Disease, Transgenes, Muscular dystrophy, Molecular Biology, Gene, Genetics (clinical), 030304 developmental biology, Gene Editing, Regulation of gene expression, 0303 health sciences, Gene knockdown, Genetic disorder, Genetic Therapy, General Medicine, Dependovirus, medicine.disease, Combined Modality Therapy, Gene Expression Regulation, 030217 neurology & neurosurgery
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ba590c9a17fc0a5b963a2ef2e4bb3c0Test
https://doi.org/10.1093/hmg/ddz128Test -
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المؤلفون: Peter Muir, Zhengling Hao, Connie S. Chamberlain, Benjamin W. Yarnall
المصدر: Veterinary Surgery. 48:1005-1012
مصطلحات موضوعية: Pathology, medicine.medical_specialty, 040301 veterinary sciences, Macrophage polarization, C-C chemokine receptor type 7, Proinflammatory cytokine, 0403 veterinary science, 03 medical and health sciences, Dogs, 0302 clinical medicine, Synovitis, Osteoarthritis, Synovial Fluid, medicine, Animals, Synovial fluid, Dog Diseases, Prospective Studies, Rupture, General Veterinary, CD68, business.industry, Anterior Cruciate Ligament Injuries, Macrophages, 04 agricultural and veterinary sciences, M2 Macrophage, medicine.disease, Stifle, Case-Control Studies, 030220 oncology & carcinogenesis, Ligaments, Articular, Joint Diseases, business, CD163, Biomarkers
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b82dbc93871335b00c36688bc1acfe1Test
https://doi.org/10.1111/vsu.13261Test -
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المؤلفون: Matthew A. Halanski, Connie S. Chamberlain, Ray Vanderby, Geoffrey S. Baer, Ugeun Choi, Peiman Hematti, Anna E. B. Clements, John A. Kink
المصدر: Stem Cells (Dayton, Ohio)
مصطلحات موضوعية: Achilles tendon injury, Mesenchymal stromal cells, Cell- and Tissue-Based Therapy, Neovascularization, Physiologic, Inflammation, Biology, Regenerative Medicine, Tendon healing, Mesenchymal Stem Cell Transplantation, Achilles Tendon, Mice, medicine, Animals, Humans, Macrophage, Cell Proliferation, Wound Healing, Achilles tendon, Macrophages, Mesenchymal stem cell, Endothelial Cells, Mesenchymal Stem Cells, Cell Biology, Extracellular vesicle, Extracellular vesicles, Disease Models, Animal, medicine.anatomical_structure, Cancer research, Molecular Medicine, medicine.symptom, Achilles tendon rupture, Stem cell, Wound healing, Developmental Biology
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a69356a27379cc95c152d399e3b8099Test
https://doi.org/10.1002/stem.2988Test -
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المؤلفون: Jeffrey S. Chamberlain, Glen B. Banks, Guy L. Odom
المصدر: PLoS Genetics
PLoS Genetics, Vol 16, Iss 11, p e1009179 (2020)مصطلحات موضوعية: Cancer Research, Utrophin, Physiology, Genetic enhancement, Muscle Fibers, Skeletal, Endogeny, Immunostaining, QH426-470, Biochemistry, Nervous System, Dystrophin, Mice, 0302 clinical medicine, Sarcolemma, Animal Cells, Medicine and Health Sciences, Morphogenesis, Myocyte, Musculoskeletal System, Genetics (clinical), Staining, 0303 health sciences, biology, Muscles, Gastrocnemius Muscles, Gene Transfer Techniques, Neuromuscular Junctions, Dependovirus, musculoskeletal system, Cell biology, Electrophysiology, Anatomy, Cellular Types, Muscle Regeneration, Muscle Contraction, Research Article, Genetic Vectors, Neuromuscular Junction, Muscle Tissue, Neurophysiology, Research and Analysis Methods, Sarcolemmas, 03 medical and health sciences, Genetics, Animals, Humans, Regeneration, Muscle, Skeletal, Molecular Biology, Ecology, Evolution, Behavior and Systematics, 030304 developmental biology, Muscle Cells, Specific force, Biology and Life Sciences, Proteins, Genetic Therapy, Cell Biology, Muscular Dystrophy, Duchenne, Disease Models, Animal, Microscopy, Electron, Cytoskeletal Proteins, HEK293 Cells, Biological Tissue, Skeletal Muscles, Specimen Preparation and Treatment, Synapses, biology.protein, Mice, Inbred mdx, Organism Development, 030217 neurology & neurosurgery, Neuroscience, Developmental Biology
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea5e5beaf8e83f1cb59a68636fd0fe39Test
https://pubmed.ncbi.nlm.nih.gov/33175853Test