المساهمون: SeongShick Ryu, Jung-Eun Park, Young Jin Ham, Daniel C Lim, Nicholas P Kwiatkowski, Do-Hee Kim, Debabrata Bhunia, Nam Doo Kim, Michael B Yaffe, Woolim Son, Namkyoung Kim, Tae-Ik Choi, Puspanjali Swain, Cheol-Hee Kim, Jin-Young Lee, Nathanael S Gray, Kyung S Lee, Taebo Sim, Sim, Taebo

مصطلحات موضوعية: Animals, Cell Cycle Proteins / antagonists & inhibitors, Cell Cycle Proteins / chemistry, Cell Cycle Proteins / metabolism, HEK293 Cells, HeLa Cells, Humans, Molecular Docking Simulation, Molecular Structure, Peptides, Cyclic / chemical synthesis, Cyclic / metabolism, Cyclic / pharmacology, Peptidomimetics / chemical synthesis, Peptidomimetics / metabolism, Peptidomimetics / pharmacology, Protein Binding, Protein Domains, Protein Kinase Inhibitors / chemical synthesis, Protein Kinase Inhibitors / metabolism, Protein Kinase Inhibitors / pharmacology, Protein Serine-Threonine Kinases / antagonists & inhibitors, Protein Serine-Threonine Kinases / chemistry, Protein Serine-Threonine Kinases / metabolism, Proto-Oncogene Proteins / antagonists & inhibitors, Proto-Oncogene Proteins / chemistry, Proto-Oncogene Proteins / metabolism, Structure-Activity Relationship, Zebrafish

العلاقة: JOURNAL OF MEDICINAL CHEMISTRY; J01588; OAK-2022-00700; https://ir.ymlib.yonsei.ac.kr/handle/22282913/188018Test; T202200436; JOURNAL OF MEDICINAL CHEMISTRY, Vol.65(3) : 1915-1932, 2022-01

الإتاحة: https://doi.org/10.1021/acs.jmedchem.1c01359Test
https://ir.ymlib.yonsei.ac.kr/handle/22282913/188018Test

المؤلفون: Yang, Z., Liang, S.Q., Yang, H., Xu, D., Bruggmann, R., Gao, Y., Deng, H., Berezowska, S., Hall, SRR, Marti, T.M., Kocher, G.J., Zhou, Q., Schmid, R.A., Peng, R.W.

المصدر: Cancer research, vol. 81, no. 11, pp. 3121-3133

مصطلحات موضوعية: Aged, Animals, Apoptosis, Benzamides/pharmacology, CRISPR-Cas Systems, Cell Cycle, Cell Cycle Proteins/antagonists & inhibitors, Cell Cycle Proteins/genetics, Cell Proliferation, Combined Modality Therapy, Gene Amplification, Gene Expression Regulation, Neoplastic, Humans, Lung Neoplasms/genetics, Lung Neoplasms/metabolism, Lung Neoplasms/pathology, Lung Neoplasms/therapy, Male, Mice, Piperazines/pharmacology, Protein Kinase Inhibitors/pharmacology, Protein Serine-Threonine Kinases/antagonists & inhibitors, Protein Serine-Threonine Kinases/genetics, Proto-Oncogene Proteins/antagonists & inhibitors, Proto-Oncogene Proteins/genetics, Pyrazoles/pharmacology, Receptor, Fibroblast Growth Factor, Type 1/antagonists & inhibitors

وصف الملف: application/pdf

العلاقة: info:eu-repo/semantics/altIdentifier/pmid/33685992; info:eu-repo/semantics/altIdentifier/eissn/1538-7445; info:eu-repo/semantics/altIdentifier/urn/urn:nbn:ch:serval-BIB_6D844130F3DD5; https://serval.unil.ch/notice/serval:BIB_6D844130F3DDTest; urn:issn:0008-5472; https://serval.unil.ch/resource/serval:BIB_6D844130F3DD.P001/REF.pdfTest; http://nbn-resolving.org/urn/resolver.pl?urn=urn:nbn:ch:serval-BIB_6D844130F3DD5Test

الإتاحة: https://doi.org/10.1158/0008-5472.CAN-20-2276Test
https://serval.unil.ch/notice/serval:BIB_6D844130F3DDTest
https://serval.unil.ch/resource/serval:BIB_6D844130F3DD.P001/REF.pdfTest
http://nbn-resolving.org/urn/resolver.pl?urn=urn:nbn:ch:serval-BIB_6D844130F3DD5Test

المؤلفون: Hu, Yiguo, Liu, Yuhua, Pelletier, Shawn, Buchdunger, Elisabeth, Warmuth, Markus, Fabbro, Doriano, Hallek, Michael, Van Etten, Richard A, Li, Shaoguang

المصدر: Nature genetics. 36(5)

مصطلحات موضوعية: Animals, Benzamides, Burkitt Lymphoma: enzymology, pathology, Cell Division: drug effects, Drug Therapy, Combination, Enzyme Activation, Enzyme Inhibitors: pharmacology, Fusion Proteins, bcr-abl: metabolism, Humans, Leukemia, Myelogenous, Chronic, BCR-ABL Positive: enzymology, pathology, Male, Mice, Mice, Inbred BALB C, Mice, Inbred C57BL, Mice, Knockout, Piperazines: pharmacology, Protein-Tyrosine Kinases: antagonists & inhibitors, physiology, Proto-Oncogene Proteins: antagonists & inhibitors, physiology, Proto-Oncogene Proteins c-hck, Pyrimidines: pharmacology, Pyrroles: pharmacology, src-Family Kinases: antagonists & inhibitors, physiology

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/9pq0v9wmTest

المؤلفون: Shun-Qing Liang, Haibin Deng, Ren-Wang Peng, Gregor J. Kocher, Sabina Berezowska, Qinghua Zhou, Zhang Yang, Rémy Bruggmann, Sean Hall, Yanyun Gao, Duo Xu, Thomas M. Marti, Ralph A. Schmid, Haitang Yang

المصدر: Cancer research, vol. 81, no. 11, pp. 3121-3133

مصطلحات موضوعية: 0301 basic medicine, Cancer Research, animal structures, Aged, Animals, Apoptosis, Benzamides/pharmacology, CRISPR-Cas Systems, Cell Cycle, Cell Cycle Proteins/antagonists & inhibitors, Cell Cycle Proteins/genetics, Cell Proliferation, Combined Modality Therapy, Gene Amplification, Gene Expression Regulation, Neoplastic, Humans, Lung Neoplasms/genetics, Lung Neoplasms/metabolism, Lung Neoplasms/pathology, Lung Neoplasms/therapy, Male, Mice, Piperazines/pharmacology, Protein Kinase Inhibitors/pharmacology, Protein Serine-Threonine Kinases/antagonists & inhibitors, Protein Serine-Threonine Kinases/genetics, Proto-Oncogene Proteins/antagonists & inhibitors, Proto-Oncogene Proteins/genetics, Pyrazoles/pharmacology, Receptor, Fibroblast Growth Factor, Type 1/antagonists & inhibitors, Receptor, Fibroblast Growth Factor, Type 1/genetics, Tumor Cells, Cultured, Xenograft Model Antitumor Assays, Cas9, DNA damage, business.industry, Drug resistance, medicine.disease, PLK1, 3. Good health, 03 medical and health sciences, 030104 developmental biology, 0302 clinical medicine, Oncology, 030220 oncology & carcinogenesis, embryonic structures, Cancer cell, Cancer research, medicine, CRISPR, Kinome, biological phenomena, cell phenomena, and immunity, Lung cancer, business

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3974a8b4da8571f690f7572bb8db80fTest
https://doi.org/10.1158/0008-5472.can-20-2276Test

المؤلفون: Cuttano, Roberto, Rudini, Noemi, Bravi, Luca, Corada, Monica, Giampietro, Costanza, Papa, Eleanna, Morini, Marco Francesco, Maddaluno, Luigi, Baeyens, Nicolas, Adams, Ralf H, Jain, Mukesh MK, Owens, Gary GK, Schwartz, Martin A, Lampugnani, Maria Grazia, Dejana, Elisabetta

المصدر: EMBO molecular medicine, 8 (1

مصطلحات موضوعية: Sciences bio-médicales et agricoles, Animals, Bone Morphogenetic Protein 6 -- antagonists & inhibitors -- genetics -- metabolism, Cell Proliferation, Disease Models, Animal, Disease Progression, Endothelial Cells -- cytology -- metabolism, HEK293 Cells, Hemangioma, Cavernous, Central Nervous System -- genetics -- metabolism -- pathology, Humans, Kruppel-Like Transcription Factors -- antagonists & inhibitors -- genetics -- metabolism, Mice, Inbred C57BL, Knockout, Microtubule-Associated Proteins -- antagonists & inhibitors -- genetics -- metabolism, Mitogen-Activated Protein Kinase 7 -- metabolism, Mutation, Proto-Oncogene Proteins -- antagonists & inhibitors -- genetics -- metabolism, RNA Interference, Signal Transduction, Smad1 Protein -- metabolism, Transforming Growth Factor beta -- metabolism, CCM, EndMT, KLF4, TGFβ‐BMP, endothelial cells

وصف الملف: 1 full-text file(s): application/pdf

العلاقة: uri/info:doi/10.15252/emmm.201505433; uri/info:pii/emmm.201505433; uri/info:pmid/26612856; uri/info:pmcid/PMC4718159; https://dipot.ulb.ac.be/dspace/bitstream/2013/260000/4/doi_243627.pdfTest; http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/260000Test

الإتاحة: http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/260000Test

المؤلفون: Andrade Da Cunha, Daniel, Igoillo Esteve, Mariana, Gurzov, Esteban Nicolas, Germano, Carla Maria Ramos C.M., Naamane, Najib, Marhfour, Ihsane, Fukaya, Makiko, Vanderwinden, Jean-Marie, Gysemans, Conny, Mathieu, Chantal, Marselli, Lorella, Marchetti, Piero, Harding, Heather HP, Ron, David, Eizirik, Decio, Cnop, Miriam

المصدر: Diabetes (New York, N.Y.), 61 (11

مصطلحات موضوعية: Sciences bio-médicales et agricoles, Aged, Animals, Apoptosis, Apoptosis Regulatory Proteins -- antagonists & inhibitors -- genetics -- metabolism, Cell Line, Cells, Cultured, Endoplasmic Reticulum Stress, Gene Expression Profiling, Humans, Insulin-Secreting Cells -- cytology -- metabolism, Male, Mice, Inbred C57BL, Knockout, Middle Aged, Mitochondria -- metabolism, Palmitic Acid -- adverse effects, Proto-Oncogene Proteins -- antagonists & inhibitors -- genetics -- metabolism, RNA Interference, RNA, Messenger -- metabolism, Small Interfering, Rats

وصف الملف: 1 full-text file(s): application/pdf

العلاقة: uri/info:doi/10.2337/db12-0123; uri/info:pii/db12-0123; uri/info:pmid/22773666; uri/info:pmcid/PMC3478544; https://dipot.ulb.ac.be/dspace/bitstream/2013/222103/1/doi_205730.pdfTest; http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/222103Test

الإتاحة: http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/222103Test

المؤلفون: Gary Gk Owens, Roberto Cuttano, Monica Corada, Ralf H. Adams, Marco Francesco Morini, Martin A. Schwartz, Maria Grazia Lampugnani, Elisabetta Dejana, Costanza Giampietro, Luigi Maddaluno, Nicolas Baeyens, Noemi Rudini, Mukesh Mk Jain, Eleanna Papa, Luca Bravi

المصدر: EMBO molecular medicine, 8 (1
Cuttano, R, Rudini, N, Bravi, L, Corada, M, Giampietro, C, Papa, E, Morini, M F, Maddaluno, L, Baeyens, N, Adams, R H, Jain, M K, Owens, G K, Schwartz, M, Lampugnani, M G & Dejana, E 2016, ' KLF4 is a key determinant in the development and progression of cerebral cavernous malformations ', EMBO Molecular Medicine, vol. 8, no. 1, PMID 26612856, pp. 6-24 . https://doi.org/10.15252/emmm.201505433Test
EMBO Molecular Medicine, 8 (1)
EMBO Molecular Medicine

مصطلحات موضوعية: 0301 basic medicine, Hemangioma, Cavernous, Central Nervous System, Vascular Biology & Angiogenesis, Bone Morphogenetic Protein 6, Proto-Oncogene Proteins -- antagonists & inhibitors -- genetics -- metabolism, Microtubule-Associated Proteins -- antagonists & inhibitors -- genetics -- metabolism, TGF beta-BMP, Cardiovascular System, Mice, Transforming Growth Factor beta, EndMT, News & Views, KRIT1 Protein, Endothelial Cells -- cytology -- metabolism, Mice, Knockout, Basic Medicine, Sciences bio-médicales et agricoles, Phenotype, Hemangioma, Cavernous, Central Nervous System -- genetics -- metabolism -- pathology, KLF4, endothelial cells, 3. Good health, Bone morphogenetic protein 6, medicine.anatomical_structure, TGFβ‐BMP, embryonic structures, Disease Progression, Molecular Medicine, RNA Interference, Smad1 Protein -- metabolism, Signal transduction, Microtubule-Associated Proteins, Signal Transduction, CCM, Endothelial cells, TGFβ-BMP, Medicinska och farmaceutiska grundvetenskaper, Central nervous system, Kruppel-Like Transcription Factors, Mitogen-Activated Protein Kinase 7 -- metabolism, Biology, Bone morphogenetic protein, Smad1 Protein, 03 medical and health sciences, Kruppel-Like Factor 4, Kruppel-Like Transcription Factors -- antagonists & inhibitors -- genetics -- metabolism, Proto-Oncogene Proteins, medicine, Animals, Humans, Transforming Growth Factor beta -- metabolism, Mitogen-Activated Protein Kinase 7, Cell Proliferation, HEK 293 cells, Endothelial Cells, Transforming growth factor beta, Bone Morphogenetic Protein 6 -- antagonists & inhibitors -- genetics -- metabolism, Mice, Inbred C57BL, Disease Models, Animal, 030104 developmental biology, HEK293 Cells, Mutation, Cancer research, biology.protein, Genetics, Gene Therapy & Genetic Disease

وصف الملف: application/pdf; 1 full-text file(s): application/pdf; application/application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40d09206d63d5e3952c0a878de00d86eTest
http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-276831Test

المؤلفون: Bruce, E, Shenoy, V, Rathinasabapathy, A, Espejo, A, Horowitz, A, Oswalt, A, Francis, J, Nair, A, Unger, T, Raizada, M K, Steckelings, Ulrike Muscha, Sumners, C, Katovich, M J

المصدر: Bruce , E , Shenoy , V , Rathinasabapathy , A , Espejo , A , Horowitz , A , Oswalt , A , Francis , J , Nair , A , Unger , T , Raizada , M K , Steckelings , U M , Sumners , C & Katovich , M J 2015 , ' Selective activation of angiotensin AT 2 receptors attenuates progression of pulmonary hypertension and inhibits cardiopulmonary fibrosis ' , British Journal of Pharmacology , vol. 172 , no. 9 , pp. 2219-2231 . https://doi.org/10.1111/bph.13044Test

مصطلحات موضوعية: Angiotensin II Type 2 Receptor Blockers/pharmacology, Angiotensin II/analogs & derivatives, Animals, Cardiovascular Agents/pharmacology, Disease Models, Animal, Fibrosis, Hemodynamics/drug effects, Hypertension, Pulmonary/chemically induced, Hypertrophy, Right Ventricular/chemically induced, Imidazoles/pharmacology, Lung/drug effects, Male, Monocrotaline, Myocardium/metabolism, Peptide Fragments/pharmacology, Proto-Oncogene Proteins/antagonists & inhibitors, Pulmonary Fibrosis/chemically induced, Pyridines/pharmacology, Rats, Sprague-Dawley, Receptor, Angiotensin, Type 2/agonists, Receptors, G-Protein-Coupled/antagonists & inhibitors, Signal Transduction/drug effects, Vascular Remodeling/drug effects

العلاقة: https://portal.findresearcher.sdu.dk/da/publications/9a3e9de0-246f-4aaf-bda2-dd58392a466dTest

الإتاحة: https://doi.org/10.1111/bph.13044Test
https://portal.findresearcher.sdu.dk/da/publications/9a3e9de0-246f-4aaf-bda2-dd58392a466dTest

المؤلفون: Bruce, E, Shenoy, V, Rathinasabapathy, A, Espejo, A, Horowitz, A, Oswalt, A, Francis, J, Nair, A, Unger, T, Raizada, M K, Steckelings, Ulrike Muscha, Sumners, C, Katovich, M J

المصدر: Bruce, E, Shenoy, V, Rathinasabapathy, A, Espejo, A, Horowitz, A, Oswalt, A, Francis, J, Nair, A, Unger, T, Raizada, M K, Steckelings, U M, Sumners, C & Katovich, M J 2015, ' Selective activation of angiotensin AT 2 receptors attenuates progression of pulmonary hypertension and inhibits cardiopulmonary fibrosis ', British Journal of Pharmacology, vol. 172, no. 9, pp. 2219-2231 . https://doi.org/10.1111/bph.13044Test

مصطلحات موضوعية: Male, Myocardium/metabolism, Pyridines, Angiotensin II Type 2 Receptor Blockers/pharmacology, Hypertension, Pulmonary, Pulmonary Fibrosis, Ventricular Dysfunction, Right, Proto-Oncogene Proteins/antagonists & inhibitors, Ventricular Remodeling/drug effects, Angiotensin II Type 2 Receptor Blockers, Vascular Remodeling, Proto-Oncogene Mas, Receptor, Angiotensin, Type 2, Receptors, G-Protein-Coupled, Rats, Sprague-Dawley, Signal Transduction/drug effects, Proto-Oncogene Proteins, Animals, Angiotensin II/analogs & derivatives, Ventricular Dysfunction, Right/chemically induced, Lung, Imidazoles/pharmacology, Pyridines/pharmacology, Receptors, G-Protein-Coupled/antagonists & inhibitors, Peptide Fragments/pharmacology, Monocrotaline, Lung/drug effects, Hypertrophy, Right Ventricular, Ventricular Remodeling, Angiotensin II, Myocardium, Ventricular Function, Right/drug effects, Hemodynamics, Imidazoles, Pulmonary Fibrosis/chemically induced, Hypertrophy, Right Ventricular/chemically induced, Cardiovascular Agents, Receptor, Angiotensin, Type 2/agonists, Research Papers, Fibrosis, Peptide Fragments, Disease Models, Animal, Hemodynamics/drug effects, Cardiovascular Agents/pharmacology, Hypertension, Pulmonary/chemically induced, Ventricular Function, Right, Vascular Remodeling/drug effects, Signal Transduction

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::b3e044c48f01f109844d8f467705bbddTest
https://europepmc.org/articles/PMC4403089Test/

المؤلفون: Gazit, Aviv, Yee, Kevin, Uecker, Andrea, Böhmer, Frank-D., Sjöblom, Tobias, Östman, Arne, Waltenberger, Johannes, Golomb, Gershon, Banai, Shmuel, Heinrich, Michael C., Levitzki, Alexander

المصدر: Bioorganic & Medicinal Chemistry. 11(9):2007-2018

مصطلحات موضوعية: Animals, Cell Line, Enzyme Inhibitors/chemistry/*pharmacology, Humans, Proto-Oncogene Proteins/*antagonists & inhibitors/metabolism, Proto-Oncogene Proteins c-kit/*metabolism, Quinoxalines/chemistry/*pharmacology, Receptor Protein-Tyrosine Kinases/*antagonists & inhibitors/metabolism, Receptors, Platelet-Derived Growth Factor/*antagonists & inhibitors/metabolism, Swine, fms-Like Tyrosine Kinase 3

وصف الملف: print

الوصول الحر: https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-10494Test
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Retrieve&list_uids=12670652&dopt=CitationTest