المؤلفون: Klinsmann Carolo dos Santos, Camilla Olofsson, João Paulo M. C. M. Cunha, Fiona Roberts, Sergiu‐Bogdan Catrina, Malin Fex, Neda Rajamand Ekberg, Peter Spégel

المصدر: Acta physiologica (Oxford, England). 236(4)

مصطلحات موضوعية: Adult, Blood Glucose, Glycated Hemoglobin, Cross-Over Studies, Physiology, Palmitates, Nutrients, Middle Aged, Glucagon, Mice, Glucose, Diabetes Mellitus, Type 2, Glucagon-Like Peptide 1, Animals, Humans, Insulin, Obesity, Aged

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4f8ced57fb315a63119080a9abdbd8bTest
https://pubmed.ncbi.nlm.nih.gov/36056607Test

المؤلفون: Hindrik Mulder, Peter Spégel

المصدر: Journal of Molecular Biology

مصطلحات موضوعية: Anabolism, medicine.medical_treatment, Enteroendocrine cell, Biology, Mass Spectrometry, Islets of Langerhans, 03 medical and health sciences, 0302 clinical medicine, Metabolomics, Structural Biology, Insulin-Secreting Cells, medicine, Animals, Humans, Insulin, Secretion, Molecular Biology, 030304 developmental biology, 0303 health sciences, Catabolism, Nutrients, Metabolism, Cell biology, Diabetes Mellitus, Type 2, Metabolome, 030217 neurology & neurosurgery, Hormone

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::645e003bfd27a6c320dee7b364ef270aTest
https://doi.org/10.1016/j.jmb.2019.07.020Test

المؤلفون: Anna-Karin Larsson-Callerfelt, Irene Rodríguez-Meizoso, Oskar Rosmark, Alicia Gil-Ramírez, Gunilla Westergren-Thorsson, Karl Swärd, Peter Spégel

المصدر: Scientific Reports, Vol 10, Iss 1, Pp 1-12 (2020)
Scientific Reports

مصطلحات موضوعية: Quality of life, 0301 basic medicine, Swine, lcsh:Medicine, 02 engineering and technology, Pulmonary Artery, Article, Extracellular matrix, 03 medical and health sciences, chemistry.chemical_compound, Medical research, In vivo, Animals, Solvent composition, lcsh:Science, Analytical biochemistry, Multidisciplinary, Decellularization, Chromatography, Tissue Scaffolds, lcsh:R, Carbon Dioxide, 021001 nanoscience & nanotechnology, Lipids, Supercritical fluid, Extracellular Matrix, 3. Good health, 030104 developmental biology, chemistry, Carbon dioxide, lcsh:Q, 0210 nano-technology

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9a0b09dcbe35dced9957d99408b216fTest
http://link.springer.com/article/10.1038/s41598-020-60827-4Test

المؤلفون: David G. Nicholls, Anya Wernersson, Vamsi K. Mootha, Peter Spégel, Kimberli J. Kamer, H. Barnard, Elaine Cowan, Neelanjan Vishnu, Annika Bagge, Alexander Hamilton, Malin Fex, Anders Tengholm, Hindrik Mulder, Y. Sancak

المصدر: Molecular Metabolism, Vol 51, Iss, Pp 101239-(2021)
Molecular Metabolism

مصطلحات موضوعية: 0301 basic medicine, Male, Voltage-dependent calcium channels, chemistry.chemical_element, 030209 endocrinology & metabolism, Mitochondrial calcium uniporter, Calcium, Mitochondrion, Bioenergetics, 03 medical and health sciences, Mice, 0302 clinical medicine, Insulin-Secreting Cells, Insulin Secretion, Animals, Humans, Uniporter, Inner mitochondrial membrane, Molecular Biology, Internal medicine, Mice, Knockout, Calcium-Binding Proteins, Cell Biology, Hyperpolarization (biology), RC31-1245, Cell biology, Mitochondria, Rats, Cytosol, 030104 developmental biology, HEK293 Cells, chemistry, Cell culture, Gene Knockdown Techniques, Stimulus-secretion coupling, Mitochondrial Membranes, Original Article, Female, Calcium Channels, Intracellular, Knockout mice

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::896292a8a6b0f86d39660eb55ca5d9ffTest
http://www.sciencedirect.com/science/article/pii/S2212877821000843Test

المؤلفون: Vladimir V. Sharoyko, Hindrik Mulder, Neelanjan Vishnu, Anya Medina, David G. Nicholls, Peter Spégel, Lisa M. Nicholas, Malin Fex

المصدر: Journal of Endocrinology. 236:R145-R159

مصطلحات موضوعية: 0301 basic medicine, medicine.medical_specialty, Transcription, Genetic, Endocrinology, Diabetes and Metabolism, medicine.medical_treatment, Cell, Oxidative phosphorylation, Type 2 diabetes, Disease, Mitochondrion, Mice, 03 medical and health sciences, Endocrinology, Insulin-Secreting Cells, Internal medicine, Insulin Secretion, Translational regulation, medicine, Animals, Humans, Glycolysis, business.industry, Insulin, medicine.disease, Mitochondria, Mice, Inbred C57BL, Glucose, 030104 developmental biology, medicine.anatomical_structure, Diabetes Mellitus, Type 2, Protein Biosynthesis, Calcium, Energy Metabolism, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7ae350e968a70db2729aebb66cc4761Test
https://doi.org/10.1530/joe-17-0367Test

المؤلفون: Liliya Shcherbina, Malin Fex, Nils Wierup, Neelanjan Vishnu, Claudia Balderas Arroyo, Claes B. Wollheim, Lotta Andersson, Mahmoud Al-Majdoub, Jonathan Aste Carrara, Peter Spégel, Hindrik Mulder

المصدر: Diabetes, Vol. 67, No 3 (2018) pp. 372-384

مصطلحات موضوعية: 0301 basic medicine, Enteroendocrine Cells, Glutamine, Endocrinology, Diabetes and Metabolism, medicine.medical_treatment, Enzyme-Linked Immunosorbent Assay, Carbohydrate metabolism, Models, Biological, Catechin, Cell Line, 03 medical and health sciences, Glutamate Dehydrogenase, Glutamates, Administration, Rectal, Glucagon-Like Peptide 1, Insulin-Secreting Cells, Insulin Secretion, Internal Medicine, medicine, Animals, Insulin, Secretion, Enzyme Inhibitors, ddc:612, Chemistry, Glutamate dehydrogenase, Metabolism, Glucagon-like peptide-1, Peptide Fragments, Mitochondria, Rats, Enzyme Activation, Mice, Inbred C57BL, Glucose, 030104 developmental biology, Biochemistry, Female, Single-Cell Analysis, Intestinal L Cells

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c1cc6446d1531afadc9a0f33c97255dTest
https://doi.org/10.2337/db16-1441Test

المؤلفون: Ian R. Sweet, Hindrik Mulder, Jean-Christophe Jonas, Peter Spégel, Heeyoung Chae, Carole Muller, Arnaldo H. de Souza, Laila Romagueira Bichara dos Santos, Hilton Kenji Takahashi

المساهمون: UCL - SSS/IREC/EDIN - Pôle d'endocrinologie, diabète et nutrition

المصدر: Molecular Metabolism, Vol. 6, no. 6, p. 535-547 (2017)
Molecular Metabolism, Vol 6, Iss 6, Pp 535-547 (2017)
Molecular Metabolism

مصطلحات موضوعية: 0301 basic medicine, Redox-sensitive GFP, Mitochondrion, Mice, chemistry.chemical_compound, GSIS, glucose stimulation of insulin secretion, Mitochondrial shuttles, [Ca2+]i, intracellular Ca2+ concentration, Insulin-Secreting Cells, Glutaredoxin, DTT, dithiotreitol, Dz, diazoxide, Insulin, OCR, oxygen consumption rate, Cells, Cultured, Glucose metabolism, Insulin secretion, GRX1, glutaredoxin 1, Mitochondrial shuttle, ME, malic enzyme, Glutathione, NNT, nicotinamide nucleotide transhydrogenase, medicine.anatomical_structure, Mitochondrial matrix, GRX1-roGFP2, Original Article, Female, AT2, aldrithiol, Oxidation-Reduction, lcsh:Internal medicine, endocrine system, medicine.medical_specialty, IDH, isocitrate dehydrogenase, Biology, KRB, Krebs solution, Exocytosis, NADP Transhydrogenase, AB-Specific, Pancreatic islet, Mitochondrial Proteins, 03 medical and health sciences, health services administration, Internal medicine, C57BL/6J mice, C57BL/6N mice, medicine, Animals, ddc:610, lcsh:RC31-1245, Molecular Biology, 030102 biochemistry & molecular biology, Pancreatic islets, CMV, cytomegalovirus, Cell Biology, WT, wild-type, Mice, Inbred C57BL, Cytosol, Glucose, 030104 developmental biology, Endocrinology, chemistry, Stimulus-secretion coupling, FCCP, carbonyl cyanide-p-trifluoromethoxyphenylhydrazone, Calcium, Carbonyl cyanide-p-trifluoromethoxyphenylhydrazone, NADP

وصف الملف: application/octet-stream

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c758fdf0926d9dd70b439b45b682dd7Test
https://doi.org/10.1016/j.molmet.2017.04.004Test

المؤلفون: Petter Storm, Anders Rosengren, Lotta Andersson, Vladimir V. Sharoyko, Isabel Göhring, Peter Spégel, Hindrik Mulder

المصدر: Endocrinology. 156:1995-2005

مصطلحات موضوعية: Male, 0301 basic medicine, medicine.medical_specialty, Metabolite, Lactate dehydrogenase A, Cell, Population, Biology, Islets of Langerhans, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Endocrinology, Insulin-Secreting Cells, Internal medicine, Gene expression, medicine, Animals, Insulin, Metabolomics, Rats, Wistar, education, geography, education.field_of_study, geography.geographical_feature_category, Glutamate receptor, Metabolism, Islet, Rats, Glucose, 030104 developmental biology, medicine.anatomical_structure, chemistry, 030217 neurology & neurosurgery

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1eb90213cf7c5cf85969b5978f02eb2Test
https://doi.org/10.1210/en.2014-1391Test

المؤلفون: James D. Johnson, Thomas Reinbothe, Joshua Millstein, Anna Wendt, Sonja Hänzelmann, Sofia Salö, Jinling Wang, Malin Fex, Hindrik Mulder, Annika Bagge, Taman Mahdi, B Mecham, Xia Yang, Anders Rosengren, Tania Singh, Peter Spégel, Ivan G. Costa, Eduardo G. Gusmao, Jonathan M. J. Derry, Enming Zhang, Claes B. Wollheim, Lena Eliasson, Bin Zhang, Le Shu, Isabella Artner, Annika S. Axelsson, M Szabat, Hannah Nenonen, Yunzhao Tang

المصدر: Nature Communications, Vol. 8 (2017) P. 15652
Nature Communications, Vol 8, Iss 1, Pp 1-16 (2017)
Nature Communications 8, 15652 (2017). doi:10.1038/ncomms15652

مصطلحات موضوعية: 0301 basic medicine, Male, endocrine system diseases, Regulator, General Physics and Astronomy, Mice, Insulin-Secreting Cells, Gene expression, Insulin, RNA, Small Interfering, Oligonucleotide Array Sequence Analysis, Regulation of gene expression, Gene knockdown, Multidisciplinary, Phenotype, Chromatin, Insulin oscillation, Female, Beta cell, SOXD Transcription Factors, endocrine system, medicine.medical_specialty, Science, Biology, General Biochemistry, Genetics and Molecular Biology, Exocytosis, Diabetes Mellitus, Experimental, 03 medical and health sciences, Islets of Langerhans, Insulin resistance, Internal medicine, medicine, Animals, Humans, ddc:612, Valproic Acid, nutritional and metabolic diseases, General Chemistry, medicine.disease, Rats, Mice, Inbred C57BL, 030104 developmental biology, Endocrinology, Phlorhizin, Diabetes Mellitus, Type 2, Gene Expression Regulation, Calcium, Calcium Channels

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec7bea2c4c995c64a58f986b5f944ebeTest
https://pubmed.ncbi.nlm.nih.gov/28643804Test

المؤلفون: Julie, Adam, Reshma, Ramracheya, Margarita V, Chibalina, Nicola, Ternette, Alexander, Hamilton, Andrei I, Tarasov, Quan, Zhang, Eduardo, Rebelato, Nils J G, Rorsman, Rafael, Martín-Del-Río, Amy, Lewis, Gizem, Özkan, Hyun Woong, Do, Peter, Spégel, Kaori, Saitoh, Keiko, Kato, Kaori, Igarashi, Benedikt M, Kessler, Christopher W, Pugh, Jorge, Tamarit-Rodriguez, Hindrik, Mulder, Anne, Clark, Norma, Frizzell, Tomoyoshi, Soga, Frances M, Ashcroft, Andrew, Silver, Patrick J, Pollard, Patrik, Rorsman

المصدر: Repositorio Institucional de la Consejería de Sanidad de la Comunidad de Madrid
Consejería de Sanidad de la Comunidad de Madrid
Cell Reports, Vol 20, Iss 13, Pp 3135-3148 (2017)
Cell Reports

مصطلحات موضوعية: endocrine system, fumarate hydratase, insulin, fumarate, diabetes, pH, glucose metabolism, mouse model, β cell, Article, Islets of Langerhans, Mice, lcsh:Biology (General), Diabetes Mellitus, Type 2, Insulin-Secreting Cells, Animals, Humans, hyperglycemia, succination, lcsh:QH301-705.5

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::48d3b9987dee790820050727259da981Test
https://hdl.handle.net/20.500.12530/30286Test