المؤلفون: Stephen R. Brooks, Hong-Wei Sun, Vittorio Sartorelli, Kan Jiang, Marco Sandri, Laura Ortet, Stefania Dell'Orso, Srikanth Ravichandran, Sonia Alonso-Martin, Aster H. Juan, Laura García-Prat, Victoria Moiseeva, Marta Flández, Eusebio Perdiguero, Vanessa Ruiz-Bonilla, Pura Muñoz-Cánoves, Elena Rebollo, Mercè Jardí, Antonio Musarò, Xiaotong Hong, Antonio del Sol, Silvia Campanario

المساهمون: Ministerio de Economía y Competitividad (España), Ministerio de Ciencia, Innovación y Universidades (España), Agencia Estatal de Investigación (España), European Commission, Foundation for the National Institutes of Health, Fundación Severo Ochoa

المصدر: Nature Cell Biology
Digital.CSIC. Repositorio Institucional del CSIC
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مصطلحات موضوعية: aging, satellite cells, foxO, stem-cell, Male, Antigens, CD34, Cell Cycle Proteins, Mice, SCID, 0302 clinical medicine, Cell Self Renewal, Stem Cell Niche, Cells, Cultured, Cellular Senescence, Mice, Knockout, 0303 health sciences, Forkhead Box Protein O1, Forkhead Box Protein O3, Age Factors, Quiescent state, Forkhead Transcription Factors, Cell biology, Phenotype, medicine.anatomical_structure, 030220 oncology & carcinogenesis, Signal Transduction, Myogenic differentiation, Satellite Cells, Skeletal Muscle, education, Biology, Cardiotoxins, 03 medical and health sciences, Muscle stem cells, medicine, Animals, Regeneration, Muscle, Skeletal, Protein kinase B, Cell Proliferation, 030304 developmental biology, Skeletal muscle, Cell Biology, Mice, Inbred C57BL, Young age, Gene Expression Regulation, Ageing, Proto-Oncogene Proteins c-akt, Homeostasis, Muscle stem cell

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9bd712fed7a626160dc61b98ee2ae203Test
https://doi.org/10.1038/s41556-020-00593-7Test

المؤلفون: Tian Luo, Zhao Li, Xue-Mei Deng, Kan Jiang, Dan Liu, Hong-Hua Zhang, Tao Shi, Lin-Yi Liu, Huai-Xiu Wen, Qi-En Li, Zhen Wang

المصدر: Bioorganic & Medicinal Chemistry. 60:116705

مصطلحات موضوعية: Organic Chemistry, Clinical Biochemistry, Mice, Nude, Pharmaceutical Science, Apoptosis, Isoquinolines, Biochemistry, Mice, Phosphatidylinositol 3-Kinases, Alkaloids, Corydalis, Stomach Neoplasms, Drug Discovery, Animals, Humans, Molecular Medicine, Molecular Biology

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69cb313021ed46c71d3e6eea53f0bf9eTest
https://doi.org/10.1016/j.bmc.2022.116705Test

المؤلفون: Kan Jiang, Xiao-Bo Zhao, Xin-yue Chen, Yan-Ping Shi, Wei Ha

المصدر: ACS Applied Materials & Interfaces. 10:21149-21159

مصطلحات موضوعية: Drug, Materials science, Combination therapy, media_common.quotation_subject, 02 engineering and technology, 010402 general chemistry, 01 natural sciences, Micelle, Combination drug therapy, Drug Delivery Systems, Neoplasms, Animals, Prodrugs, General Materials Science, Cytotoxicity, Micelles, media_common, Drug Carriers, Prodrug, 021001 nanoscience & nanotechnology, 0104 chemical sciences, Cascade, Biophysics, Drug Therapy, Combination, Self-assembly, 0210 nano-technology

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a70b42fc8a4476386c1d8acdf465174bTest
https://doi.org/10.1021/acsami.8b05170Test

المؤلفون: Xiaofei Deng, Kan Jiang, Jinxia Zhang, Jing Wang, Binjiao Yin, Feili Gong, John J. O'Shea, Yu Xia, Jae Jin Chae, Hongping Ba, Arian Laurence, Na Liu, Zhuoya Li, Yongwon Choi, Xiang Cheng, Yao Yao, Lin Li, Guoyu Bi, Xiuxiu Xie, Zhaohui Tang, Xiang-Ping Yang

مصطلحات موضوعية: Salmonella typhimurium, 0301 basic medicine, Vacuolar Proton-Translocating ATPases, Inflammasomes, Protein subunit, Peritonitis, Biology, Membrane Fusion, R-SNARE Proteins, Mice, 03 medical and health sciences, Autophagy, medicine, Animals, Humans, Macrophage, V-ATPase, Molecular Biology, Cells, Cultured, Adenosine Triphosphatases, Mice, Knockout, 030102 biochemistry & molecular biology, Qa-SNARE Proteins, Macrophages, Autophagosomes, Inflammasome, Cell Biology, Colitis, Autophagosome formation, Mitochondria, Cell biology, Mice, Inbred C57BL, HEK293 Cells, 030104 developmental biology, Salmonella Infections, Autophagosome lysosome fusion, Lysosomes, human activities, Research Paper, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab4cf19855026892ca89d9067c32b258Test

المؤلفون: Rishi R. Goel, Paul R. Thompson, Yaíma L. Lightfoot, Hong-Wei Sun, Yudong Liu, Scott A. Coonrod, Erica Moore, Pragnesh Mistry, Santanu Mondal, Padmavathy Nandha Premnath, Nickie L Seto, Liam J. O’Neil, Kan Jiang, Stefania Dell'Orso, Carmelo Carmona-Rivera, Katherine Gribbons, Victoria Hoffmann, Mariana J. Kaplan

مصطلحات موضوعية: 0301 basic medicine, CD4-Positive T-Lymphocytes, Hydrolases, T-Lymphocytes, Inflammation, Biology, Adaptive Immunity, medicine.disease_cause, Extracellular Traps, Autoimmunity, Autoimmune Diseases, Histones, 03 medical and health sciences, Mice, 0302 clinical medicine, Immune system, Protein-Arginine Deiminase Type 4, Protein-Arginine Deiminase Type 2, medicine, Animals, Humans, Lupus Erythematosus, Systemic, Mice, Knockout, Systemic lupus erythematosus, Autoantibody, General Medicine, Neutrophil extracellular traps, Immune dysregulation, Th1 Cells, medicine.disease, Acquired immune system, Immunity, Innate, Disease Models, Animal, 030104 developmental biology, Gene Expression Regulation, Toll-Like Receptor 7, Immunology, Interferon Type I, Protein-Arginine Deiminases, Th17 Cells, Female, medicine.symptom, Transcriptome, 030215 immunology, Research Article

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d95abeb0d2f62d76402a5728bf77136Test
https://europepmc.org/articles/PMC6328098Test/

المؤلفون: Dragana Jankovic, Chen Yao, Alan Sher, Franziska Petermann, Catrina A. Johnson, Aleksandra Pekowska, William H. Hudson, Hong-Wei Sun, Yuka Kanno, Han-Yu Shih, Stephen R. Brooks, Kentner Singleton, Alejandro V. Villarino, Kan Jiang, Rama Akondy, John J. O'Shea, Rafael Casellas, Rafi Ahmed

المصدر: Mol Cell

مصطلحات موضوعية: RNA, Untranslated, T-Lymphocytes, Locus (genetics), Biology, Infections, Article, 03 medical and health sciences, chemistry.chemical_compound, Interferon-gamma, Mice, 0302 clinical medicine, Genetic model, medicine, Animals, Interferon gamma, Molecular Biology, 030304 developmental biology, 0303 health sciences, Gene knockdown, RNA, Cell Biology, Chromatin, Cell biology, chemistry, Gene Expression Regulation, CTCF, Gene Knockdown Techniques, Female, Immunologic Memory, 030217 neurology & neurosurgery, DNA, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b68cf0533becfe11b2ffc65afb7afccTest
https://pubmed.ncbi.nlm.nih.gov/31377117Test

المؤلفون: Yongjun Zhang, Siqi Xu, Kan Jiang

المصدر: Food & Function. 7:3868-3879

مصطلحات موضوعية: 0301 basic medicine, Arabinose, China, Antioxidant, DPPH, medicine.medical_treatment, 02 engineering and technology, Xylose, Polysaccharide, Antioxidants, Superoxide dismutase, 03 medical and health sciences, chemistry.chemical_compound, Species Specificity, Polysaccharides, Superoxides, medicine, Animals, Caenorhabditis elegans, Chelating Agents, chemistry.chemical_classification, Reactive oxygen species, biology, Superoxide Dismutase, Superoxide, Basidiomycota, Monosaccharides, Free Radical Scavengers, General Medicine, Catalase, 021001 nanoscience & nanotechnology, 030104 developmental biology, chemistry, Biochemistry, biology.protein, Reactive Oxygen Species, 0210 nano-technology, Oxidation-Reduction, Food Science

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7b65eb23767a0524b6bb9dadb7e8a33Test
https://doi.org/10.1039/c6fo00686hTest

المؤلفون: Zhengping Wei, Yu Xia, Na Liu, Huicheng Liu, Sanpeng Xu, Yaqi Duan, Guoping Wang, Shunqun Luo, Jing Luo, Arian Laurence, Fang Chen, Xiang Cheng, Zhaohui Tang, Xiang-Ping Yang, Jing Wang, Kan Jiang, Zhuoya Li, Huabin Li, Feili Gong, Xiuxiu Xie, Dong Kuang, Bingjiao Yin

المصدر: The Journal of clinical investigation. 129(2)

مصطلحات موضوعية: 0301 basic medicine, Vacuolar Proton-Translocating ATPases, Lung Neoplasms, Metabolite, Adenocarcinoma of Lung, mTORC1, Gene Expression Regulation, Enzymologic, 03 medical and health sciences, chemistry.chemical_compound, Mice, 0302 clinical medicine, medicine, Basic Helix-Loop-Helix Transcription Factors, Tumor Microenvironment, Macrophage, Animals, Humans, Lactic Acid, Tissue homeostasis, Mice, Knockout, Tumor microenvironment, Macrophages, General Medicine, medicine.disease, Phenotype, Neoplasm Proteins, Gene Expression Regulation, Neoplastic, 030104 developmental biology, chemistry, Tumor progression, 030220 oncology & carcinogenesis, Cancer research, Adenocarcinoma, Female, Research Article

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf750a2dfe6f4d5a8cb37dd3b13370d0Test
https://pubmed.ncbi.nlm.nih.gov/30431439Test

المؤلفون: Kan Jiang, Stephen C. J. Parker, Michael R. Erdos, Massimo Gadina, Francis S. Collins, Yasuko Furumoto, John J. O'Shea, Vittorio Sartorelli, Yuka Kanno, Golnaz Vahedi, Zhonghui Tang, Nicholas P. Restifo, Yijun Ruan, Sean Davis, Rahul Roychoudhuri

المصدر: Nature

مصطلحات موضوعية: RNA, Untranslated, Transcription, Genetic, Cellular differentiation, medicine.medical_treatment, P300-CBP Transcription Factors, Biology, Article, Arthritis, Rheumatoid, Mice, Piperidines, medicine, Animals, Cell Lineage, Genetic Predisposition to Disease, Pyrroles, p300-CBP Transcription Factors, IL-2 receptor, Regulation of gene expression, Genetics, Multidisciplinary, Janus kinase 3, Janus Kinase 3, Cell Differentiation, T-Lymphocytes, Helper-Inducer, Mice, Inbred C57BL, Basic-Leucine Zipper Transcription Factors, Enhancer Elements, Genetic, Pyrimidines, Cytokine, Gene Expression Regulation, Spatiotemporal gene expression, Janus kinase

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a7cafa7124f0c18292d05171d8026f8Test
https://doi.org/10.1038/nature14154Test

المؤلفون: Dunrui Wang, Ombretta Salvucci, Giovanna Tosato, Kan Jiang, Dragan Maric, Hyeongil Kwak, David Sánchez-Martín, Hidetaka Ohnuki

المصدر: Cancer Research. 74:2038-2049

مصطلحات موضوعية: Male, Cancer Research, Myeloid, Notch signaling pathway, Article, Mice, Transforming Growth Factor beta, Tumor Microenvironment, medicine, Animals, Myeloid Cells, Adaptor Proteins, Signal Transducing, Cell Proliferation, Tumor microenvironment, Receptors, Notch, biology, Calcium-Binding Proteins, Intracellular Signaling Peptides and Proteins, Membrane Proteins, Neoplasms, Experimental, Transforming growth factor beta, Squamous carcinoma, medicine.anatomical_structure, Oncology, Tumor progression, Hes3 signaling axis, Disease Progression, biology.protein, Cancer research, Cyclin-dependent kinase 8, Female, Signal Transduction

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::206af1d7f1f971ce32b71c57b5012f12Test
https://doi.org/10.1158/0008-5472.can-13-3118Test