المؤلفون: Chang, Wakam, Wang, Yuexia, Östlund, Cecilia, Worman, Howard, Gundersen, Gregg, Luxton, Gw

المصدر: Proceedings of the National Academy of Sciences of USA. 116(9)

مصطلحات موضوعية: Hutchinson–Gilford progeria syndrome, LINC complex, SUN proteins, centrosome orientation, nuclear movement, Aging, Animals, Cell Nucleus, Cell Polarity, Dyneins, Fibroblasts, Gene Expression Regulation, Humans, Lamin Type A, Membrane Proteins, Mice, Microfilament Proteins, Microtubule-Associated Proteins, NIH 3T3 Cells, Nerve Tissue Proteins, Nuclear Envelope, Nuclear Proteins, Progeria, Protein Prenylation

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/44g669rkTest

المؤلفون: Christina Manakanatas, Santhosh Kumar Ghadge, Azra Agic, Fatih Sarigol, Petra Fichtinger, Irmgard Fischer, Roland Foisner, Selma Osmanagic-Myers

المصدر: Aging (Albany NY)

مصطلحات موضوعية: Aging, integumentary system, Down-Regulation, Aorta, Thoracic, Cell Biology, senescence-associated micro RNAs, Atherosclerosis, Lamin Type A, Hutchinson-Gilford progeria syndrome, Up-Regulation, Mice, MicroRNAs, Progeria, Gene Expression Regulation, cardiovascular disease, endothelial senescence, Paracrine Communication, Animals, Endothelium, Vascular, RNA, Messenger, Tumor Suppressor Protein p53, Cellular Senescence, Research Paper

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::164366cc8189269bf555e5916bae4beeTest
http://europepmc.org/articles/PMC8791216Test

المؤلفون: Vicente Andrés, Magda R. Hamczyk

المساهمون: Ministerio de Ciencia, Innovación y Universidades (España), European Regional Development Fund (ERDF/FEDER), Progeria Research Foundation, Fundacio La Marato, Fundación ProCNIC, Instituto de Salud Carlos III

المصدر: Nucleus, Vol 10, Iss 1, Pp 48-54 (2019)
Nucleus
Repisalud
Instituto de Salud Carlos III (ISCIII)
Scopus
RUO. Repositorio Institucional de la Universidad de Oviedo
instname

مصطلحات موضوعية: Premature aging, congenital, hereditary, and neonatal diseases and abnormalities, Vascular smooth muscle, lcsh:QH426-470, Cellular differentiation, Disease, Muscle, Smooth, Vascular, LMNA, 03 medical and health sciences, Progeria, medicine, Animals, Humans, vascular smooth muscle cells, lcsh:QH573-671, 030304 developmental biology, lamin A, 0303 health sciences, integumentary system, business.industry, lcsh:Cytology, Extra View, 030302 biochemistry & molecular biology, nutritional and metabolic diseases, Cell Biology, medicine.disease, Progerin, Lamin Type A, Atherosclerosis, Hutchinson-Gilford progeria syndrome, lcsh:Genetics, progerin, Cancer research, atherosclerosis, business, Lamin, hutchinson-gilford progeria syndrome, lamin a

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2f615358e3f276e90d7de7571bb59ceTest
https://doaj.org/article/f44fdf8a65c245f1b6a1e4410d172064Test

المؤلفون: Rivera-Torres, José, Calvo, Conrado J, Llach, Anna, Guzmán-Martínez, Gabriela, Caballero, Ricardo, González-Gómez, Cristina, Jiménez-Borreguero, Luis J, Guadix, Juan A, Osorio, Fernando G, López-Otín, Carlos, Herraiz-Martínez, Adela, Cabello, Nuria, Vallmitjana, Alex, Benítez, Raul, Gordon, Leslie B, Jalife, José, Pérez-Pomares, José M, Tamargo, Juan, Delpón, Eva, Hove-Madsen, Leif, Filgueiras-Rama, David, Andrés, Vicente

مصطلحات موضوعية: Hutchinson–Gilford progeria syndrome, calcium handling, connexin43, prelamin A, progerin, Adolescent, Adult, Animals, Arrhythmias, Cardiac, Calcium, Cardiac Conduction System Disease, Child, Preschool, Connexin 43, Female, Heart, Humans, Male, Membrane Proteins, Metalloendopeptidases, Mice, Inbred C57BL, Knockout, Myocardium, Nuclear Lamina, Progeria, Sarcoplasmic Reticulum, Young Adult

العلاقة: http://hdl.handle.net/10668/10568Test; PMC5135377; https://europepmc.org/articles/pmc5135377?pdf=renderTest; https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5135377/pdfTest

الإتاحة: https://doi.org/10.1073/pnas.1603754113Test
http://hdl.handle.net/10668/10568Test
https://europepmc.org/articles/pmc5135377?pdf=renderTest
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5135377/pdfTest

المؤلفون: Ricardo Villa-Bellosta

المصدر: Proc Natl Acad Sci U S A

مصطلحات موضوعية: Male, 0301 basic medicine, 030204 cardiovascular system & hematology, Pyrophosphate, Mice, chemistry.chemical_compound, Adenosine Triphosphate, Progeria, 0302 clinical medicine, Gene Knock-In Techniques, Pyrophosphatases, RNA, Small Interfering, media_common, Multidisciplinary, integumentary system, Apyrase, Longevity, Calcinosis, Biological Sciences, Lamin Type A, Diphosphates, RNA Interference, Hutchinson Gilford Progeria Syndrome, congenital, hereditary, and neonatal diseases and abnormalities, medicine.medical_specialty, media_common.quotation_subject, Myocytes, Smooth Muscle, Aortic Diseases, Mice, Transgenic, Real-Time Polymerase Chain Reaction, 03 medical and health sciences, Antigens, CD, Internal medicine, medicine, Animals, Humans, Vascular calcification, Phosphoric Diester Hydrolases, business.industry, nutritional and metabolic diseases, Alkaline Phosphatase, medicine.disease, Disease Models, Animal, 030104 developmental biology, Endocrinology, Levamisole, chemistry, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2fc5d2c846386409bed45f6b6a6f47f5Test
https://doi.org/10.1073/pnas.1910972116Test

المؤلفون: Sussan Nourshargh, Loïc Rolas, María J. Andrés-Manzano, Beatriz Dorado, Víctor Fanjul, Ignacio Benedicto, Carla Espinós-Estévez, Pilar Gonzalo, Magda R. Hamczyk, Raquel Riquelme-Borja, Lara Del Campo, Jesús Vázquez, Alvaro Macias, Emilio Camafeita, Amanda Sánchez-López, Cristina González-Gómez, Anna Barkaway, Vicente Andrés

المساهمون: Ministerio de Ciencia e Innovación (España), Agencia Estatal de Investigación (España), Unión Europea. Comisión Europea. H2020, Unión Europea. Fondo Europeo de Desarrollo Regional (FEDER/ERDF), Asociación Apadrina la Ciencia-Ford España-Ford Motor Company Fund, Fundación La Caixa, Comunidad de Madrid (España), Instituto de Salud Carlos III, Fundación ProCNIC, Ministerio de Ciencia e Innovación. Centro de Excelencia Severo Ochoa (España)

المصدر: Circulation

مصطلحات موضوعية: Premature aging, medicine.medical_specialty, Myocytes, Smooth Muscle, cardiac myocyte, Mice, Transgenic, Disease, Muscle, Smooth, Vascular, smooth muscle, Mice, Progeria, Physiology (medical), Internal medicine, Original Research Articles, medicine, Animals, Humans, Myocytes, Cardiac, Myocardial infarction, Stroke, integumentary system, business.industry, cell, Progerin, medicine.disease, Lamin Type A, Hutchinson-Gilford progeria syndrome, Disease Models, Animal, Heart failure, Cardiology, ComputingMethodologies_DOCUMENTANDTEXTPROCESSING, Cardiology and Cardiovascular Medicine, business, Lamin

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b306bba104ae2c185182e39402ab1beTest
https://pubmed.ncbi.nlm.nih.gov/34694158Test

المؤلفون: Vicente Andrés, Beatriz Dorado, Ignacio Benedicto

المساهمون: Ministerio de Ciencia e Innovación (España), Instituto de Salud Carlos III, Unión Europea. Comisión Europea. H2020, Unión Europea. Fondo Europeo de Desarrollo Regional (FEDER/ERDF), Progeria Research Foundation, Fundación La Marató TV3, Comunidad de Madrid (España), Fundación ProCNIC

المصدر: Cells
Cells, Vol 10, Iss 1157, p 1157 (2021)

مصطلحات موضوعية: 0301 basic medicine, Aging, Myocardial Infarction, Disease, Review, 030204 cardiovascular system & hematology, Bioinformatics, Cardiovascular System, endothelial dysfunction, Muscle, Smooth, Vascular, Mice, 0302 clinical medicine, Progeria, cardiovascular disease, Myocardial infarction, Biology (General), Endothelial dysfunction, Stroke, Cytoskeleton, Clinical Trials as Topic, integumentary system, General Medicine, Progerin, Lamin Type A, vessel stiffening, Physiological Aging, Phenotype, Cardiovascular Diseases, congenital, hereditary, and neonatal diseases and abnormalities, Heart Diseases, QH301-705.5, extracellular matrix, 03 medical and health sciences, progeroid animal models, medicine, Animals, Humans, Vascular Calcification, Hutchinson-Gilford progeria syndrome (HGPS), business.industry, fibrosis, nutritional and metabolic diseases, Muscle, Smooth, medicine.disease, Atherosclerosis, Fibrosis, Disease Models, Animal, 030104 developmental biology, Heart failure, progerin, Endothelium, Vascular, vascular smooth muscle cell, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c457295db5bc0418addb0cd861a1c7a6Test
http://europepmc.org/articles/PMC8151355Test

المؤلفون: Paul Wanschoor, Simon Willaume, Pascale Bertrand, Emilie Rass, Paula Fontanilla-Ramirez, Angela Moussa

المصدر: Genes, Vol 12, Iss 552, p 552 (2021)
Genes

مصطلحات موضوعية: 0301 basic medicine, Genome instability, Senescence, DNA Replication, cGAS-STING pathway, senescence, lcsh:QH426-470, DNA repair, DNA damage, Inflammation, Review, Biology, Genomic Instability, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Genetics, medicine, cancer, Animals, Humans, Genetics (clinical), aging, genome instability, DNA replication stress, Double Strand Break Repair, Lamins, Hutchinson-Gilford progeria syndrome, Cell biology, lcsh:Genetics, Oxidative Stress, 030104 developmental biology, chemistry, 030220 oncology & carcinogenesis, double-strand break repair, medicine.symptom, DNA, Lamin, DNA Damage

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::433a63d4abfad0bef94b2c07871f7669Test
https://pubmed.ncbi.nlm.nih.gov/33918867Test

المؤلفون: Villa-Bellosta, Ricardo, Rivera-Torres, Jose, Osorio, Fernando G, Acin-Perez, Rebeca, Enriquez, Jose Antonio, López-Otín, Carlos, Andres, Vicente

المساهمون: Ministerio de Economía y Competitividad (España), Instituto de Salud Carlos III, Progeria Research Foundation, Botín Foundation, Fundación Cajastur, Fundación ProCNIC

مصطلحات موضوعية: ATP, Hutchinson-Gilford progeria syndrome, muscle, Progerin, Pyrophosphate, Tissue-non specific alkaline phosphatase, Vascular calcification, Smooth, Adenosine Triphosphate, Alkaline Phosphatase, Animals, Aorta, Cells, Cultured, Diphosphates, Disease Models, Animal, Lamin Type A, Male, Mice, Inbred C57BL, Mutant Strains, Mitochondria, Vascular, Progeria, Treatment Outcome

العلاقة: Postprint; https://doi.org/10.1161/CIRCULATIONAHA.112.000571Test; info:eu-repo/grantAgreement/ES/SAF2010-16044; info:eu-repo/grantAgreement/ES/RD06/0014/0021; info:eu-repo/grantAgreement/ES/RD12/0042/0028; info:eu-repo/grantAgreement/ES/JCI-2011-09663; Circulation. 2013; 127(24):2442-51; http://hdl.handle.net/20.500.12105/7754Test; Circulation

الإتاحة: https://doi.org/20.500.12105/7754Test
https://doi.org/10.1161/CIRCULATIONAHA.112.000571Test
https://hdl.handle.net/20.500.12105/7754Test

المؤلفون: Yaazan Blanco, María J. Andrés-Manzano, José Jalife, Víctor Fanjul, Pilar Gonzalo, David Filgueiras-Rama, Andre Monteiro da Rocha, Vicente Andrés, J Jaime Díaz-Larrosa, Cristina González-Gómez, Alvaro Macias, Andrew Allan, Daniela Ponce-Balbuena

المساهمون: Ministerio de Ciencia e Innovación (España), Instituto de Salud Carlos III, Unión Europea. Fondo Europeo de Desarrollo Regional (FEDER/ERDF), Progeria Research Foundation, Ministerio de Ciencia e Innovación. Centro de Excelencia Severo Ochoa (España), Fundación ProCNIC, NIH - National Heart, Lung, and Blood Institute (NHLBI) (Estados Unidos)

المصدر: Cardiovascular Research

مصطلحات موضوعية: Male, Refractory Period, Electrophysiological, Physiology, Swine, Cardiac index, Action Potentials, Laminopathy, Afterdepolarization, Progerin, Progeria, Heart Rate, Tubulin, Myocytes, Cardiac, AcademicSubjects/MED00200, Cytoskeleton, Excitation Contraction Coupling, Cardiomyocytes, integumentary system, Lamin Type A, Electrophysiology, Cardiology, Swine, Miniature, Female, Electrical conduction system of the heart, Cardiology and Cardiovascular Medicine, Anti-Arrhythmia Agents, medicine.medical_specialty, Paclitaxel, Cardiac Electrophysiology and Arrhythmia, Heart Conduction System, Physiology (medical), Internal medicine, Animal model of cardiovascular disease, Cardiac conduction, medicine, Repolarization, Animals, Genetic Predisposition to Disease, Lamin A/C, Hutchinson–Gilford progeria syndrome, business.industry, Arrhythmias, Cardiac, Original Articles, medicine.disease, Mice, Mutant Strains, Disease Models, Animal, Mutation, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f24170b70fb89a7a0130672f81004c0Test
https://pubmed.ncbi.nlm.nih.gov/33624748Test