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1
المؤلفون: Sara Lopes, Thorsten Schmidt, Clévio Nóbrega, Miguel Monteiro Lopes, Dineke S. Verbeek, Diana Lobo, Dina Pereira, Ana Vasconcelos-Ferreira, Luís Pereira de Almeida, Inês Morgado Martins, Rosário Faro
المساهمون: Movement Disorder (MD), Molecular Neuroscience and Ageing Research (MOLAR)
المصدر: Molecular Therapy, 30(1), 370-387. CELL PRESS
Mol Therمصطلحات موضوعية: congenital, hereditary, and neonatal diseases and abnormalities, Ataxia, Intranuclear Inclusions, Neuropathology, Mutant Huntingt, Biology, Neuroprotection, Mice, Cerebellar-Aaxiagene-Productcell-Lines, Drug Discovery, Genetics, medicine, Transcriptional regulation, Nuclear-Localization, Autophagy, Animals, Ataxin-3, Molecular Biology, Pharmacology, ULK2, Machado-Joseph Disease, ULK1, Dependovirus, medicine.disease, Cell biology, Disease Models, Animal, Molecular Medicine, Original Article, Polyglutamine-Expanded Ataxin-3, Rat Modelin-Vitro, medicine.symptom, Machado–Joseph disease
وصف الملف: application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6624ead970bd32025df3f2fed67eab6Test
https://hdl.handle.net/11370/6e7d478b-8917-4de9-ba98-76e5ef115fc2Test -
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المؤلفون: Sandra Macedo-Ribeiro, Luís Pereira de Almeida, Bruno Almeida, Clévio Nóbrega, Susana R. Louros, Ana Luísa Carvalho, Elisabete Ferreiro, Jorge Valero, Carlos A. Matos
المساهمون: Instituto de Investigação e Inovação em Saúde
المصدر: Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
The Journal of Cell Biology
Europe PubMed Centralمصطلحات موضوعية: Male, 0301 basic medicine, Time Factors, medicine.disease_cause, Synapse, Serine, 0302 clinical medicine, Transgenic mice, Phosphorylation, Ataxin-3, Mutant ataxin-3, Research Articles, Cerebral Cortex, Neurons, Mutation, Machado-Joseph Disease, Cell biology, Expanded ataxin-3, Biochemistry, Spinocerebellar ataxia, Rat model, RNA Interference, Protein ataxin-3, Machado–Joseph disease, Signal Transduction, congenital, hereditary, and neonatal diseases and abnormalities, Molecular Sequence Data, Gestational Age, Biology, Transfection, Neuroprotection, Article, 03 medical and health sciences, medicine, Animals, Humans, Amino Acid Sequence, Rats, Wistar, Cell Biology, Repeat expansion, Fibroblasts, medicine.disease, Clinical-features, Repressor Proteins, Disease Models, Animal, Polyglutamine disease, HEK293 Cells, 030104 developmental biology, nervous system, Ataxin, Machado-joseph-disease, Nerve Degeneration, Synapses, Huntingtin phosphorylation, Peptides, 030217 neurology & neurosurgery
وصف الملف: application/pdf; text/plain
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::caa8599ef81658f39793e775da0d11fcTest
https://hdl.handle.net/10216/108249Test -
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المؤلفون: Yi Hsin Weng, Tu Hsueh Yeh, Hung Li Wang, Si Ying Chen, An Hsun Chou
المصدر: Neurobiology of Disease, Vol 41, Iss 2, Pp 481-488 (2011)
مصطلحات موضوعية: Transcriptional Activation, Genetically modified mouse, Cerebellum, congenital, hereditary, and neonatal diseases and abnormalities, Transgene, Down-Regulation, Mice, Transgenic, Nerve Tissue Proteins, Histone Deacetylases, lcsh:RC321-571, Mice, chemistry.chemical_compound, Downregulation and upregulation, Spinocerebellar ataxia type 3, medicine, Animals, Histone deacetylase, Enzyme Inhibitors, Polyglutamine-expanded ataxin-3, Ataxin-3, lcsh:Neurosciences. Biological psychiatry. Neuropsychiatry, Ataxin-1, biology, Nuclear Proteins, Acetylation, Sodium butyrate, Machado-Joseph Disease, Histone acetyltransferase, Molecular biology, Cell biology, Repressor Proteins, Phenotype, Histone, medicine.anatomical_structure, Ataxins, Neurology, chemistry, SCA3 transgenic mice, biology.protein, Butyric Acid
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::764adb266c7489328157913970c7d266Test
http://www.sciencedirect.com/science/article/pii/S0969996110003530Test -
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المؤلفون: Tu Hsueh Yeh, Hung Li Wang, Pin Ouyang, Ying Ling Chen, Si Ying Chen, An Hsun Chou
المصدر: Neurobiology of Disease, Vol 31, Iss 1, Pp 89-101 (2008)
مصطلحات موضوعية: Genetically modified mouse, Cerebellum, Ataxia, Transcription, Genetic, Transgene, Blotting, Western, Gene Expression, Mice, Transgenic, Substantia nigra, Biology, lcsh:RC321-571, Mice, Spinocerebellar ataxia type 3, Heat shock protein, medicine, Animals, Humans, RNA, Messenger, Polyglutamine-expanded ataxin-3, Ataxin-3, lcsh:Neurosciences. Biological psychiatry. Neuropsychiatry, Oligonucleotide Array Sequence Analysis, Reverse Transcriptase Polymerase Chain Reaction, Neurodegeneration, Nuclear Proteins, Microarray analysis, Machado-Joseph Disease, medicine.disease, Immunohistochemistry, Molecular biology, Cell biology, Blotting, Southern, Disease Models, Animal, medicine.anatomical_structure, Neurology, nervous system, Ataxin, SCA3 transgenic mice, medicine.symptom, Peptides, Trinucleotide Repeat Expansion, Transcription Factors
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9fdf1f8f122593d4685fa8d75ff9efdTest
http://www.sciencedirect.com/science/article/pii/S0969996108000673Test -
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المؤلفون: Shu Ru Tsai, Mei Jie Jou, An Hsun Chou, Akira Kakizuka, Yu Cheng Kao, Hung Li Wang, Yu Li Kuo, Chia Yu Hsu, Tu Hsueh Yeh
المصدر: Neurobiology of Disease, Vol 21, Iss 2, Pp 333-345 (2006)
مصطلحات موضوعية: Cerebellum, Blotting, Western, bcl-X Protein, Down-Regulation, Bcl-xL, Substantia nigra, Nerve Tissue Proteins, Apoptosis, lcsh:RC321-571, Downregulation and upregulation, Spinocerebellar ataxia type 3, medicine, In Situ Nick-End Labeling, Animals, Spinocerebellar Ataxias, RNA, Messenger, Polyglutamine-expanded ataxin-3, Ataxin-3, lcsh:Neurosciences. Biological psychiatry. Neuropsychiatry, Cells, Cultured, bcl-2-Associated X Protein, Neurons, TUNEL assay, biology, Reverse Transcriptase Polymerase Chain Reaction, Brain, Nuclear Proteins, medicine.disease, Molecular biology, Mitochondria, Rats, Up-Regulation, Repressor Proteins, Disease Models, Animal, medicine.anatomical_structure, Neurology, nervous system, Bax, Ataxin, Polyglutamine neurodegenerative disorders, Mutation, biology.protein, Spinocerebellar ataxia, Peptides
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f3d5d13429a6fd76667d9d2033e65a3Test
http://www.sciencedirect.com/science/article/pii/S0969996105002123Test