المؤلفون: Kip P. Conner, Min-Zu Wu, Jiamiao Lu, Aazam Ghelani, Yi-Ling Hu, Darren L. Bates, Ashutosh Chaudhry, Sue J. Sohn, Chi-Ming Li

المصدر: Frontiers in Immunology
Frontiers in Immunology, Vol 11 (2020)

مصطلحات موضوعية: lcsh:Immunologic diseases. Allergy, 0301 basic medicine, Immunology, Lymphocyte Activation, Protein Engineering, T-Lymphocytes, Regulatory, law.invention, 03 medical and health sciences, Mice, Structure-Activity Relationship, 0302 clinical medicine, law, In vivo, Immunology and Allergy, Animals, Humans, IL-2 receptor, Receptor, STAT5, Original Research, tolerance, biology, Chemistry, IL-2, autoimmunity, In vitro, Recombinant Proteins, regulatory T, Cell biology, Treg, 030104 developmental biology, inflammation, Humanized mouse, biology.protein, Suppressor, Phosphorylation, Interleukin-2, mutein, lcsh:RC581-607, 030215 immunology, Protein Binding

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c5300a7e9e52e6055f1cfa65656b9afTest
https://pubmed.ncbi.nlm.nih.gov/32582190Test

المؤلفون: Ching-Shin Huang, Caroline Gundel, Ben C. Chung, Joanne Lin, Qing Chen, Liying Deng, Darren L. Bates, Zhulun Wang, Jinghong Wang, Jie Yang, Murielle M. Véniant, David Lloyd, Xiaoshan Min, Stephen A. Thibault, Haoda Xu, Christina Abbott, Tina Meng, Junming Yie

المصدر: mAbs

مصطلحات موضوعية: Male, endocrine system, medicine.medical_specialty, Protein Conformation, Immunology, Diet, High-Fat, Weight Gain, Receptors, Gastrointestinal Hormone, Mice, Immune system, Report, Internal medicine, medicine, Animals, Immunology and Allergy, structure, Obesity, crystallography, Receptor, GIPR, biology, Chemistry, Antibodies, Monoclonal, Lipid metabolism, Mice, Inbred C57BL, Endocrinology, Incretin Hormone, Molecular mechanism, biology.protein, antagonistic antibody, Glucose-dependent insulinotropic polypeptide, Antibody, Antagonism, hormones, hormone substitutes, and hormone antagonists

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5ec036e73660230e011396dc0673377Test
https://doi.org/10.1080/19420862.2019.1710047Test

المؤلفون: Brandon C. P. Clavette, Xiaoshan Min, Joanne Lin, Elizabeth A. Killion, Robert J.M. Kurzeja, David Lloyd, Liying Deng, Zhulun Wang, Clarence Hale, Christopher Murawsky, Stone D.-H. Shi, Murielle M. Véniant, Jinghong Wang, James B. Rottman, Christina Abbott, Todd Hager, Lu Shu Chen, Junming Yie, Ian Foltz, Qing Chen, Stephen A. Thibault, Darren L. Bates, Renee Komorowski, Larissa Atangan, Glenn Sivits, Tina Meng

المصدر: Science Translational Medicine. 10

مصطلحات موضوعية: Primates, 0301 basic medicine, endocrine system, medicine.medical_specialty, Recombinant Fusion Proteins, Glucagon-Like Peptides, Mice, Obese, Genome-wide association study, Gastric Inhibitory Polypeptide, Weight Gain, Antibodies, Glucagon-Like Peptide-1 Receptor, Receptors, Gastrointestinal Hormone, 03 medical and health sciences, 0302 clinical medicine, Weight loss, Insulin-Secreting Cells, Internal medicine, Weight Loss, Conditional gene knockout, Adipocytes, Animals, Humans, Medicine, Obesity, Receptor, Respiratory exchange ratio, biology, business.industry, Respiration, Feeding Behavior, General Medicine, Liraglutide, medicine.disease, Diet, Immunoglobulin Fc Fragments, 030104 developmental biology, Endocrinology, 030220 oncology & carcinogenesis, Knockout mouse, biology.protein, Drug Therapy, Combination, medicine.symptom, Antibody, business, hormones, hormone substitutes, and hormone antagonists

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4219a5cd6927493203264b2541e2f88bTest
https://doi.org/10.1126/scitranslmed.aat3392Test

المؤلفون: Lin Chen, Yongheng Chen, Darren L. Bates, Grace Kim, Liang Guo

المصدر: Journal of Molecular Biology. 381:1292-1306

مصطلحات موضوعية: Models, Molecular, Molecular Sequence Data, GATA zinc finger, GATA3 Transcription Factor, Biology, Crystallography, X-Ray, Protein Structure, Secondary, Article, Mice, Structure-Activity Relationship, Structural Biology, Transcription (biology), Animals, Amino Acid Sequence, Binding site, Molecular Biology, Transcription factor, Genetics, Zinc finger, Binding Sites, GATA2, GATA3, Zinc Fingers, DNA, Protein Structure, Tertiary, embryonic structures, GATA transcription factor, Dimerization, Protein Binding

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa2430bf4d819b8222fca96a84441081Test
https://doi.org/10.1016/j.jmb.2008.06.072Test

المؤلفون: Aron M. Levin, K. Christopher Garcia, Paul Novick, Aaron M. Ring, Miro E. Raeber, Leon Su, Jack T. Lin, Gregory R. Bowman, C. Garrison Fathman, Onur Boyman, Vijay S. Pande, Darren L. Bates, Carsten Krieg, Ignacio Moraga

المساهمون: University of Zurich, Garcia, K Christopher

المصدر: Nature

مصطلحات موضوعية: Models, Molecular, Receptor complex, Protein Conformation, medicine.medical_treatment, T-Lymphocytes, Crystallography, X-Ray, Protein Engineering, Mice, 0302 clinical medicine, Neoplasms, STAT5 Transcription Factor, Cytotoxic T cell, IL-2 receptor, Phosphorylation, 0303 health sciences, Multidisciplinary, ZAP70, 10177 Dermatology Clinic, 3. Good health, Cell biology, Killer Cells, Natural, Cytokine, Immunotherapy, medicine.drug, Interleukin 2, 610 Medicine & health, Streptamer, Biology, Molecular Dynamics Simulation, Article, Cell Line, 03 medical and health sciences, Immune system, medicine, Animals, Humans, 030304 developmental biology, Cell Proliferation, 1000 Multidisciplinary, Binding Sites, Interleukin-2 Receptor alpha Subunit, Surface Plasmon Resonance, Molecular biology, Interleukin-2 Receptor beta Subunit, Mice, Inbred C57BL, Mutation, Interleukin-2, Mutant Proteins, Directed Molecular Evolution, Neoplasm Transplantation, 030215 immunology

وصف الملف: Levin_et_al._-_Nature_2012.pdf - application/pdf; Levin_et_al_Acc-MS.pdf - application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c841d44ba8335e8595f4cd275c74e2c2Test
https://doi.org/10.5167/uzh-75564Test

المؤلفون: Steven F. Ziegler, Ariya D. Lapan, Liang Guo, Vigo Heissmeyer, Christophe Benoist, Diane Mathis, Darren L. Bates, James C. Stroud, Anjana Rao, Lin Chen, Yongqing Wu, Madhuri Borde, Markus Feuerer, Aidong Han

المصدر: Cell 126, 375-387 (2006)

مصطلحات موضوعية: Models, Molecular, Regulatory T cell, T cell, Molecular Sequence Data, Regulator, chemical and pharmacologic phenomena, Biology, Crystallography, X-Ray, Jurkat cells, T-Lymphocytes, Regulatory, General Biochemistry, Genetics and Molecular Biology, Jurkat Cells, Mice, Genes, Reporter, Mice, Inbred NOD, medicine, Animals, Humans, IL-2 receptor, Amino Acid Sequence, Luciferases, Transcription factor, Cells, Cultured, Binding Sites, NFATC Transcription Factors, Sequence Homology, Amino Acid, Biochemistry, Genetics and Molecular Biology(all), FOXP3, hemic and immune systems, NFAT, Forkhead Transcription Factors, Receptors, Interleukin-2, Recombinant Proteins, Protein Structure, Tertiary, Up-Regulation, Repressor Proteins, medicine.anatomical_structure, Retroviridae, Amino Acid Substitution, Cancer research, Interleukin-2, Dimerization, Biomarkers, Protein Binding

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2cf2739206bc744d4ba66f6b7761f55Test
https://pubmed.ncbi.nlm.nih.gov/16873058Test