-
1
المؤلفون: Paul J. Emmerson, David J. Hodson, Brandy M. Snider, Nicolas Nunn, Tamer Coskun, Jenna Hunter, Mehdi Boutagouga Boudjadja, Gabriella Aviello, Isabella Culotta, Minrong Ai, Simon M. Luckman, Alessia Costa, Giuseppe D'Agostino, Lourdes Valencia-Torres
المساهمون: Costa, A., Ai, M., Nunn, N., Culotta, I., Hunter, J., Boudjadja, M. B., Valencia-Torres, L., Aviello, G., Hodson, D. J., Snider, B. M., Coskun, T., Emmerson, P. J., Luckman, S. M., D'Agostino, G.
المصدر: Costa, A, Ai, M, Nunn, N, Culotta, I, Hunter, J, Boudjadja, M B, Valencia-Torres, L, Aviello, G, Hodson, D J, Snider, B M, Coskun, T, Emmerson, P J, Luckman, S M & D'Agostino, G 2021, ' Anorectic and aversive effects of GLP-1 receptor agonism are mediated by brainstem cholecystokinin neurons, and modulated by GIP receptor activation ', Molecular Metabolism, vol. 55, 101407 . https://doi.org/10.1016/j.molmet.2021.101407Test
Molecular Metabolism
Molecular Metabolism, Vol 55, Iss, Pp 101407-(2022)مصطلحات موضوعية: Blood Glucose, Male, Glucagon-like peptide-1, endocrine system, Glucose-dependent insulinotropic polypeptide, media_common.quotation_subject, Appetite, Gastric Inhibitory Polypeptide, Brief Communication, Glucagon-Like Peptide-1 Receptor, Receptors, Gastrointestinal Hormone, Mice, Nucleus of the solitary tract, Glucagon-Like Peptide 1, Appetite Depressants, Medicine, Animals, Hypoglycemic Agents, Insulin, Receptor, Internal medicine, Molecular Biology, Glucagon-like peptide 1 receptor, media_common, Cholecystokinin, Neurons, business.industry, Area postrema, digestive, oral, and skin physiology, Brain, Nausea, Cell Biology, Liraglutide, Glucagon, RC31-1245, Mice, Inbred C57BL, Anorectic, Exenatide, Female, Brainstem, business, Neuroscience, hormones, hormone substitutes, and hormone antagonists
وصف الملف: application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3c8f4b8195f8ad7f7f17bc35a2d9541Test
https://www.research.manchester.ac.uk/portal/en/publications/anorectic-and-aversive-effects-of-glp1Test-receptor -agonism-are-mediated-by-brainstem-cholecystokinin-neurons-and-modulated-by-gip-receptor -activation(97b025ca-ff46-4b48-a59c-edf8df09098e).html -
2
المؤلفون: Tamer Coskun, Claire H. Feetham, Giuseppe D'Agostino, Garron T. Dodd, Amy A. Worth, Frank Reimann, James D. Dunbar, Fiona M. Gribble, Simon M. Luckman, Paul J. Emmerson, Katie Tye, Emily C Beebe, Dana Sindelar, Jesline T. Alexander-Chacko, Rosemary Shoop
المساهمون: Worth, Amy A [0000-0003-2573-7140], Shoop, Rosemary [0000-0002-3617-4358], Luckman, Simon M [0000-0001-5318-5473], Apollo - University of Cambridge Repository
المصدر: Worth, A A, Shoop, R, Tye, K, Feetham, C H, D'Agostino, G, Dodd, G T, Reimann, F, Gribble, F M, Beebe, E C, Dunbar, J D, Alexander-Chacko, J T, Sindelar, D K, Coskun, T, Emmerson, P J & Luckman, S M 2020, ' The cytokine GDF15 signals through a population of brainstem cholecystokinin neurons to mediate anorectic signalling ', eLife, vol. 9, e55164, pp. 1-19 . https://doi.org/10.7554/eLife.55164Test
eLife, Vol 9 (2020)
eLifeمصطلحات موضوعية: 0301 basic medicine, Male, food intake, Lydia Becker Institute, medicine.medical_treatment, cisplatin, brainstem, neuroscience, Rats, Sprague-Dawley, Mice, Random Allocation, 0302 clinical medicine, rat, Biology (General), Receptor, Cholecystokinin, Neurons, education.field_of_study, GFRAL, General Neuroscience, Area postrema, General Medicine, Recombinant Proteins, Anorexia, Cytokine, Pica, Medicine, medicine.symptom, Signal transduction, Research Article, Signal Transduction, medicine.medical_specialty, Growth Differentiation Factor 15, QH301-705.5, Science, Population, Biology, General Biochemistry, Genetics and Molecular Biology, 03 medical and health sciences, Internal medicine, ResearchInstitutes_Networks_Beacons/lydia_becker_institute_of_immunology_and_inflammation, medicine, Animals, education, mouse, General Immunology and Microbiology, CCK, Rats, Mice, Inbred C57BL, 030104 developmental biology, Endocrinology, GDF15, nervous system, Anorectic, 030217 neurology & neurosurgery, Brain Stem
وصف الملف: application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c36fee4c12ae9aa6d1944526e39affeTest
-
3
المؤلفون: Qian Liu, Ruth E. Gimeno, Jason X. Tang, Gavin C. Barnard, Xilin Liu, Yong Du, Jorge Alsina-Fernandez, Paul J. Emmerson, Avinash Muppidi, Bei B Zhang, Richard Todd Pickard, Matthew J Hamang, Bei Shan, Tamer Coskun, Pamela Jean Mitchell, Malgorzata Donata Gonciarz, Kimberly K Ballman, John H. Sloan, Xinle Wu, Xudong Mao, Lisa A Foltz, Feng Wang, Dana Sindelar, Robert W. Siegel
المصدر: Nature Medicine. 23:1215-1219
مصطلحات موضوعية: Male, 0301 basic medicine, medicine.medical_specialty, Glial Cell Line-Derived Neurotrophic Factor Receptors, Growth Differentiation Factor 15, Immunoblotting, Biology, Real-Time Polymerase Chain Reaction, General Biochemistry, Genetics and Molecular Biology, Rats, Sprague-Dawley, Eating, Mice, 03 medical and health sciences, Estrogen-related receptor alpha, 0302 clinical medicine, Internal medicine, Weight Loss, medicine, Animals, Humans, 5-HT5A receptor, Obesity, RNA, Messenger, Receptor, Mice, Knockout, Orphan receptor, Brain, General Medicine, Surface Plasmon Resonance, Flow Cytometry, Rats, Neuron-derived orphan receptor 1, Macaca fascicularis, HEK293 Cells, 030104 developmental biology, Endocrinology, Area Postrema, ROR1, Estrogen-related receptor gamma, GDF15, 030217 neurology & neurosurgery
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2502200f39c5bdc1b589339efb20908aTest
https://doi.org/10.1038/nm.4393Test -
4
المؤلفون: Angelos Karlas, Monja Willershäuser, Tobias Fromme, Florian Bolze, Vasilis Ntziachristos, Martin Klingenspor, Sanna Laurila, Kirsi A. Virtanen, Jorge Alsina-Fernandez, Mueez U Din, Yongguo Li, Tamer Coskun, Andrea Bast-Habersbrunner, Minna Lahesmaa, Josefine Reber, Libbey S. O’Farrell, Pirjo Nuutila, Sarah-Madeleine Gabler, Katharina Schnabl
المصدر: Cell. 175:1561-1574.e12
مصطلحات موضوعية: 0301 basic medicine, medicine.medical_specialty, Lipolysis, Glucose uptake, Mice, Obese, Biology, digestive system, General Biochemistry, Genetics and Molecular Biology, Secretin, Eating, Mice, 03 medical and health sciences, Adipose Tissue, Brown, Internal medicine, medicine, Animals, Humans, Receptor, Mice, Knockout, digestive, oral, and skin physiology, Thermogenesis, ta3121, Adipocytes, Brown, HEK293 Cells, 030104 developmental biology, Postprandial, Endocrinology, Secretin receptor, hormones, hormone substitutes, and hormone antagonists, Hormone
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15dc556cb8e26641603a14156ad1f27fTest
https://doi.org/10.1016/j.cell.2018.10.016Test -
5
المؤلفون: Andreas Stengel, Jean Rivier, Jorge Alsina-Fernandez, Libbey S. Craft, Yvette Taché, Lixin Wang, Tamer Coskun, Miriam Goebel-Stengel
المصدر: Regulatory Peptides. 167:201-208
مصطلحات موضوعية: Male, Agonist, endocrine system, medicine.medical_specialty, Physiology, medicine.drug_class, Clinical Biochemistry, Weight Gain, Biochemistry, Article, Injections, Rats, Sprague-Dawley, Eating, Cellular and Molecular Neuroscience, Endocrinology, Thinness, Internal medicine, medicine, Animals, Obesity, Receptors, Somatostatin, Receptor, Somatostatin receptor, Chemistry, Body Weight, nutritional and metabolic diseases, medicine.disease, Peptide Fragments, Diet, Rats, Somatostatin, Lean body mass, medicine.symptom, Diet-induced obese, Weight gain, hormones, hormone substitutes, and hormone antagonists
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9c29d3207c860f2cc55b03169c28e9bTest
https://doi.org/10.1016/j.regpep.2011.01.006Test -
6
المؤلفون: Gary M. Green, Travis E. Solomon, Steven R. Vigna, Grace L. Rosenquist, Peter Chew, Tamer Coskun, David A. Keire, Rodger A. Liddle, Douglas C. McVey, John E. Shively, Joseph R. Reeve, Terry D. Lee
المصدر: American Journal of Physiology-Gastrointestinal and Liver Physiology. 287:G326-G333
مصطلحات موضوعية: Male, Physiology, Radioimmunoassay, Neuropeptide, In Vitro Techniques, Biology, digestive system, Sincalide, Gastric Acid, Rats, Sprague-Dawley, Mice, Dogs, Physiology (medical), Biological property, medicine, Animals, Amino Acids, Receptor, Pancreas, Cholecystokinin, Hepatology, digestive, oral, and skin physiology, Gastroenterology, Brain, Receptor, Cholecystokinin B, Rats, Receptor, Cholecystokinin A, Intestines, medicine.anatomical_structure, Biochemistry, Amylases, Gastric acid, hormones, hormone substitutes, and hormone antagonists
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91cfb4635ef9e5618dd89d6c75a75bcbTest
https://doi.org/10.1152/ajpgi.00520.2003Test -
7
المؤلفون: David A. Keire, Kym F. Faull, Peter Chew, Joseph R. Reeve, Gary M. Green, S. Vincent Wu, Tamer Coskun, Travis E. Solomon
المصدر: American Journal of Physiology-Gastrointestinal and Liver Physiology. 286:G395-G402
مصطلحات موضوعية: medicine.medical_specialty, Physiology, Radioimmunoassay, Neuropeptide, Stimulation, CHO Cells, Spectrometry, Mass, Fast Atom Bombardment, Biology, Binding, Competitive, digestive system, Mass Spectrometry, Sincalide, Rats, Sprague-Dawley, Cricetinae, Physiology (medical), Internal medicine, Casein, medicine, Animals, Bile, Potency, Anesthesia, Amino Acids, Receptor, Pancreas, Cholecystokinin, Whole blood, Hepatology, Sulfates, digestive, oral, and skin physiology, Gastroenterology, Caseins, Receptor, Cholecystokinin B, Rats, Receptor, Cholecystokinin A, Endocrinology, Amylases, hormones, hormone substitutes, and hormone antagonists
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c35c004a1a16bdea0be142aaade7ddf6Test
https://doi.org/10.1152/ajpgi.00020.2003Test -
8
المؤلفون: Travis E. Solomon, John E. Shively, David A. Keire, F.J. Ho, Michael T. Davis, Christopher J. Evans, Tamer Coskun, Gary M. Green, Terry D. Lee, Joseph R. Reeve
المصدر: Regulatory Peptides. 113:71-77
مصطلحات موضوعية: Time Factors, Physiology, Clinical Biochemistry, Neuropeptide, Peptide, Biology, digestive system, Biochemistry, Mass Spectrometry, Cellular and Molecular Neuroscience, chemistry.chemical_compound, Dogs, Endocrinology, Peptide synthesis, Animals, Amino Acids, Tyrosine, Receptor, Pancreas, Cholecystokinin, chemistry.chemical_classification, Dose-Response Relationship, Drug, digestive, oral, and skin physiology, Biological activity, Peptide Fragments, Amino acid, chemistry, Amylases, hormones, hormone substitutes, and hormone antagonists
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40a3cf278ee92910cf49525edebe2753Test
https://doi.org/10.1016/s0167-0115Test(02)00301-4 -
9
المؤلفون: James Ficorilli, Feihan Dai, Lucy S. Jun, M. Dodson Michael, Aaron D. Showalter, Kyle W. Sloop, Wenzhen Ma, Tamer Coskun, Michael B. Wheeler, Nosher Ali
المصدر: PLoS ONE
PLoS ONE, Vol 9, Iss 4, p e93746 (2014)مصطلحات موضوعية: Physiology, lcsh:Medicine, Biochemistry, Epitope, Mice, Endocrinology, Integrative Physiology, Medicine and Health Sciences, Receptors, Glucagon, Homeostasis, Insulin, lcsh:Science, Receptor, Multidisciplinary, Systems Biology, Animal Models, Cell biology, Research Design, Anatomy, Research Article, Agonist, medicine.medical_specialty, Clinical Research Design, medicine.drug_class, Transgene, Cre recombinase, Endocrine System, Mouse Models, Mice, Transgenic, Biology, Research and Analysis Methods, Glucagon-Like Peptide-1 Receptor, Model Organisms, Internal medicine, Genetics, medicine, Animals, Humans, Animal Models of Disease, Pancreas, Glucagon-like peptide 1 receptor, G protein-coupled receptor, Diabetic Endocrinology, Endocrine Physiology, Gastric emptying, lcsh:R, Biology and Life Sciences, Correction, Glucose Tolerance Test, Disease Models, Animal, Metabolism, Glucose, Diabetes Mellitus, Type 2, lcsh:Q, Endocrine-Related Substances, Endocrine Cells, Energy Metabolism, Physiological Processes, Animal Genetics
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::268e152417bb338cff0082bff035872dTest
https://pubmed.ncbi.nlm.nih.gov/26172935Test -
10
المؤلفون: Lisa Selsam Beavers, Samreen K. Syed, Tamer Coskun, Libbey S. O’Farrell, Daniel A. Briere, Mervyn D Michael, Franciskovich Jeffry Bernard, Alexander M. Efanov, Susan L. DuBois, David Gene Barrett
المصدر: Endocrinology. 154(1)
مصطلحات موضوعية: medicine.medical_specialty, medicine.medical_treatment, EP4 Receptor, Enteroendocrine cell, Gastric Inhibitory Polypeptide, Thiophenes, Biology, Real-Time Polymerase Chain Reaction, Mice, Endocrinology, Glucagon-Like Peptide 1, Internal medicine, medicine, Glucagon-Like Peptide 2, Animals, Secretion, Peptide YY, Intestinal Mucosa, Receptor, Cells, Cultured, digestive, oral, and skin physiology, Triazoles, Glucagon-like peptide-1, lipids (amino acids, peptides, and proteins), Receptors, Prostaglandin E, EP4 Subtype, Prostaglandin E, Hormone
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::386887594bb0a46da8b4ac15d84c5b69Test
https://pubmed.ncbi.nlm.nih.gov/23142807Test