نتائج البحث

المصدر: Arthritis Research & Therapy
Arthritis research & therapy, vol. 22, no. 1, pp. 49
Arthritis Research & Therapy, Vol 22, Iss 1, Pp 1-12 (2020)

مصطلحات موضوعية: 0301 basic medicine, Cartilage, Articular, medicine.medical_specialty, lcsh:Diseases of the musculoskeletal system, Sulfurtransferase, Osteoarthritis, medicine.disease_cause, Protective Agents, Mineralization (biology), Chondrocyte, 03 medical and health sciences, 0302 clinical medicine, Chondrocytes, In vivo, Internal medicine, medicine, Animals, Humans, Animal model, Chondrocyte calcification, Aged, Meniscectomy, Aged, 80 and over, Mice, Knockout, Hydrogen sulfide, Chemistry, Interleukin-6, Cartilage, Calcinosis, Calcium-containing crystals, X-Ray Microtomography, Middle Aged, Osteoarthritis, Knee, medicine.disease, Mice, Inbred C57BL, 030104 developmental biology, medicine.anatomical_structure, Endocrinology, 030220 oncology & carcinogenesis, Sulfurtransferases, Female, lcsh:RC925-935, human activities, Oxidative stress, Calcification, Research Article

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::417f073521e5b10d0e0b433381965528Test
http://europepmc.org/articles/PMC7077027Test

8

Prematurely aging mitochondrial DNA mutator mice display subchondral osteopenia and chondrocyte hypertrophy without further osteoarthritis features

المؤلفون: Gregory C. Kujoth, Magdalena Müller-Gerbl, Thomas Hügle, Sonia Nasi, Tomas A. Prolla, Pascal Distel, Ulrich A. Walker, Jeroen Geurts

المساهمون: Anatomy and neurosciences, Amsterdam Neuroscience - Neurodegeneration, Amsterdam Neuroscience - Neuroinfection & -inflammation

المصدر: Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-7 (2020)
Scientific reports, vol. 10, no. 1, pp. 1296
Geurts, J, Nasi, S, Distel, P, Müller-Gerbl, M, Prolla, T A, Kujoth, G C, Walker, U A & Hügle, T 2020, ' Prematurely aging mitochondrial DNA mutator mice display subchondral osteopenia and chondrocyte hypertrophy without further osteoarthritis features ', Scientific Reports, vol. 10, no. 1, 1296 . https://doi.org/10.1038/s41598-020-58385-wTest
Scientific Reports, 10(1):1296. Nature Publishing Group

مصطلحات موضوعية: 0301 basic medicine, Premature aging, medicine.medical_specialty, Mitochondrial DNA, Mutation, Missense, lcsh:Medicine, Chondrocyte hypertrophy, Osteoarthritis, Biology, Chondrocyte, Article, Muscle hypertrophy, 03 medical and health sciences, Mice, 0302 clinical medicine, Chondrocytes, Internal medicine, Aging, Premature/enzymology, Aging, Premature/genetics, Aging, Premature/pathology, Amino Acid Substitution, Animals, Bone Diseases, Metabolic/enzymology, Bone Diseases, Metabolic/genetics, Bone Diseases, Metabolic/pathology, Chondrocytes/enzymology, Chondrocytes/pathology, DNA Polymerase gamma/genetics, DNA Polymerase gamma/metabolism, Hypertrophy, Mice, Mutant Strains, Osteoarthritis/enzymology, Osteoarthritis/genetics, Osteoarthritis/pathology, medicine, lcsh:Science, Bone, 030203 arthritis & rheumatology, Multidisciplinary, lcsh:R, DNA damage and repair, Aging, Premature, medicine.disease, DNA Polymerase gamma, Osteopenia, Bone Diseases, Metabolic, 030104 developmental biology, medicine.anatomical_structure, Endocrinology, Osteocyte, lcsh:Q

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c50f8e2514656f46f4057372aa64ced0Test
http://europepmc.org/articles/PMC6987232Test

9

Improving metabolic stability with deuterium: The discovery of HWL ‐066, a potent and long‐acting free fatty acid receptor 1 agonists

المؤلفون: Chen Liao, Hai Qian, Chunxia Liu, Wei Shi, Wenlong Huang, Zheng Li, Nasi Wang, Yuxuan Dai, Huilan Li

المصدر: Chemical Biology & Drug Design. 92:1547-1554

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f557522c57d26f7c965af74081bb796fTest
https://doi.org/10.1111/cbdd.13321Test

10

Phenylquinoline transient receptor potential vanilloid 1 antagonists for the treatment of pain: Discovery of 1-(2-phenylquinoline-4-carbonyl)-N-(4-(trifluoromethyl)phenyl)pyrrolidine-3-carboxamide

المؤلفون: Huilan Li, Taiyu Liu, Yan Liu, Hesham Ghaleb, Jieming Li, Hai Qian, Chunxia Liu, Wenlong Huang, Jiaqi Zhou, Nasi Wang, Chen Liao

المصدر: Bioorganic & Medicinal Chemistry. 26:845-854

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13d4550c8207dad4cac516b733a8b5fdTest
https://doi.org/10.1016/j.bmc.2017.12.048Test

تنقيح النتائج