نتائج البحث - "Sebastian Bauer"

1

Pharmacokinetic–pharmacodynamic guided optimisation of dose and schedule of CGM097, an HDM2 inhibitor, in preclinical and clinical studies

المؤلفون: Stephane Ferretti, Sébastien Jeay, Ensar Halilovic, Claire Fabre, Laurence Van Bree, Christophe Meille, Jens Wuerthner, Florence Hourcade-Potelleret, Sebastian Bauer, Reinhard Dummer, Philippe A. Cassier, Astrid Jullion, George D. Demetri, Nelson Guerreiro, Daniel Shao-Weng Tan

المساهمون: University of Zurich, Bauer, Sebastian

المصدر: British Journal of Cancer

مصطلحات موضوعية: Male, Oncology, Cancer Research, Medizin, Administration, Oral, Piperazines, Mice, 0302 clinical medicine, Neoplasms, Medicine, 1306 Cancer Research, Drug Dosage Calculations, Platelet, 0303 health sciences, Drug discovery, Pharmacokinetic pharmacodynamic, 10177 Dermatology Clinic, Middle Aged, Treatment Outcome, Tolerability, 030220 oncology & carcinogenesis, Toxicity, Biomarker (medicine), 2730 Oncology, Female, Adult, medicine.medical_specialty, Growth Differentiation Factor 15, Cell Survival, 610 Medicine & health, Drug development, Article, Drug Administration Schedule, 03 medical and health sciences, In vivo, Cell Line, Tumor, Internal medicine, Biomarkers, Tumor, Animals, Humans, Dosing, Aged, Cell Proliferation, 030304 developmental biology, business.industry, Isoquinolines, Xenograft Model Antitumor Assays, Regimen, business

وصف الملف: 918_Bauer_S._et_al._Pharmacokinetic-pharmacodynamic_guided_optimisation_of_dose_and_schedule_of_CGM097,_an_HDM2_inhibitor_Br_J_Cancer_2021.pdf - application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::962edae56c80ae45d9537101a31228f2Test
https://doi.org/10.1038/s41416-021-01444-4Test

2

Circulating P2X7 Receptor Signaling Components as Diagnostic Biomarkers for Temporal Lobe Epilepsy

المؤلفون: Tobias Engel, Aida Menéndez-Méndez, Felix Rosenow, David C. Henshall, Giorgia Conte, Norman Delanty, Sebastian Bauer, Mariana Alves, Hany El-Naggar, Annette Nicke

المصدر: Cells
Volume 10
Issue 9
Cells, Vol 10, Iss 2444, p 2444 (2021)

وصف الملف: application/pdf; application/octet-stream

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d7153573f988e7883912d188a0680daTest
http://europepmc.org/articles/PMC8467140Test

3

A systems approach delivers a functional microRNA catalog and expanded targets for seizure suppression in temporal lobe epilepsy

المصدر: Venø, M T, Reschke, C R, Morris, G, Connolly, N M C, Su, J, Yan, Y, Engel, T, Jimenez-Mateos, E M, Harder, L M, Pultz, D, Haunsberger, S J, Pal, A, Heller, J P, Campbell, A, Langa, E, Brennan, G P, Conboy, K, Richardson, A, Norwood, B A, Costard, L S, Neubert, V, Gallo, F D, Salvetti, B, Vangoor, V R, Sanz-Rodriguez, A, Muilu, J, Fabene, P F, Pasterkamp, R J, Prehn, J H M, Schorge, S, Andersen, J S, Rosenow, F, Bauer, S, Kjems, J & Henshall, D C 2020, ' A systems approach delivers a functional microRNA catalog and expanded targets for seizure suppression in temporal lobe epilepsy ', Proceedings of the National Academy of Sciences of the United States of America, vol. 117, no. 27, pp. 15977-15988 . https://doi.org/10.1073/pnas.1919313117Test
Proceedings of the National Academy of Sciences
Venø, M T, Reschke, C R, Morris, G, Connolly, N M C, Su, J, Yan, Y, Engel, T, Jimenez-Mateos, E M, Harder, L M, Pultz, D, Haunsberger, S J, Pal, A, Heller, J P, Campbell, A, Langa, E, Brennan, G P, Conboy, K, Richardson, A, Norwood, B A, Costard, L S, Neubert, V, Del Gallo, F, Salvetti, B, Vangoor, V R, Sanz-Rodriguez, A, Muilu, J, Fabene, P F, Pasterkamp, R J, Prehn, J H M, Schorge, S, Andersen, J S, Rosenow, F, Bauer, S, Kjems, J & Henshall, D C 2020, ' A systems approach delivers a functional microRNA catalog and expanded targets for seizure suppression in temporal lobe epilepsy ', Proceedings of the National Academy of Sciences of the United States of America, vol. 117, no. 27, 27, pp. 15977-15988 . https://doi.org/10.1073/pnas.1919313117Test
Proceedings of the National Academy of Sciences of the United States of America

مصطلحات موضوعية: Male, Proteomics, antisense oligonucleotide, Small RNA, Systems Analysis, Hippocampus, Noncoding RNA, Rats, Sprague-Dawley, Mice, Epilepsy, 0302 clinical medicine, biomarker, epigenetic, epilepsy, noncoding RNA, Gene expression, Antisense oligonucleotide, 0303 health sciences, Gene knockdown, Multidisciplinary, Epigenetic, Biological Sciences, Argonaute, Non-coding RNA, Up-Regulation, 3. Good health, Argonaute Proteins, Female, Biology, 03 medical and health sciences, Seizures, microRNA, medicine, Animals, Humans, Epigenetics, 030304 developmental biology, Antagomirs, Biomarker, Oligonucleotides, Antisense, medicine.disease, Rats, Mice, Inbred C57BL, Disease Models, Animal, MicroRNAs, Epilepsy, Temporal Lobe, Neuroscience, Biomarkers, 030217 neurology & neurosurgery