المؤلفون: Al-Olabi, Lara, Polubothu, Satyamaanasa, Dowsett, Katherine, Andrews, Katrina A., Stadnik, Paulina, Joseph, Agnel P., Knox, Rachel, Pittman, Alan, Clark, Graeme, Baird, William, Bulstrode, Neil, Glover, Mary, Gordon, Kristiana, Hargrave, Darren, Huson, Susan M., Jacques, Thomas S., James, Gregory, Kondolf, Hannah, Kangesu, Loshan, Keppler-Noreuil, Kim M., Khan, Amjad, Lindhurst, Marjorie J., Lipson, Mark, Mansour, Sahar, O’Hara, Justine, Mahon, Caroline, Mosica, Anda, Moss, Celia, Murthy, Aditi, Ong, Juling, Parker, Victoria E., Rivière, Jean-Baptiste, Sapp, Julie C., Sebire, Neil J., Shah, Rahul, Sivakumar, Branavan, Thomas, Anna, Virasami, Alex, Waelchli, Regula, Zeng, Zhiqiang, Biesecker, Leslie G., Barnacle, Alex, Topf, Maya, Semple, Robert K., Patton, E. Elizabeth, Kinsler, Veronica A.

المصدر: Al-Olabi, L, Polubothu, S, Dowsett, K, Andrews, K A, Stadnik, P, Joseph, A P, Knox, R, Pittman, A, Clark, G, Baird, W, Bulstrode, N, Glover, M, Gordon, K, Hargrave, D, Hudson, S, Jacques, T S, James, G, Kondolf, H, Kangesu, L, Keppler-Noreuil, K M, Khan, A, Lindhurst, M J, Lipson, M, Mansour, S, O'Hara, J, Mahon, C, Mosica, A, Moss, C, Murthy, A, Ong, J, parker, V, Rivière, J-B, Sapp, J C, Sebire, N J, Shah, R, Sivakumar, B, Thomas, A, Virasami, A, Waelchli, R, Zeng, Z, Biesecker, L G, Barnacle, A, Topf, M, Semple, R K, Patton, E E & Kinsler, V A 2018, ' Mosaic RAS/MAPK variants cause sporadic vascular malformations which respond to targeted therapy ', Journal of Clinical Investigation, vol. 128, no. 4, pp. 1496-1508 . https://doi.org/10.1172/JCI98589Test
The Journal of Clinical Investigation

مصطلحات موضوعية: Adult, Male, Adolescent, MAP Kinase Signaling System, Vascular Malformations, MAP Kinase Kinase 1, Therapeutics, Signal transduction, bcs, 03 medical and health sciences, 0302 clinical medicine, Vascular Biology, Human Umbilical Vein Endothelial Cells, Animals, Humans, Molecular genetics, Child, Alleles, Zebrafish, 030304 developmental biology, 0303 health sciences, Infant, General Medicine, 3. Good health, HEK293 Cells, Phenotype, 030220 oncology & carcinogenesis, Mutation, ras Proteins, Female, Drug therapy, Erratum, Clinical Medicine

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97a787f305108175bc0a77b5fa3cf555Test
https://doi.org/10.1172/jci124649Test

المؤلفون: Clive James Gregory, Christopher J. Morris, Ghaith Aljayyoussi, Mark Gumbleton, Iain McDonald, Ian Price Matthews, Bastiaan Hoogendoorn

المصدر: Environmental Toxicology and Pharmacology. 35:461-464

مصطلحات موضوعية: Male, Mucociliary clearance, Health, Toxicology and Mutagenesis, Chromosomal translocation, Respiratory Mucosa, Carbon nanotube, In Vitro Techniques, Pharmacology, Toxicology, Systemic circulation, law.invention, Rats, Sprague-Dawley, Pharmacokinetics, Nickel, law, medicine, Animals, Lung, Nanotubes, Carbon, Chemistry, General Medicine, respiratory system, Rats, respiratory tract diseases, Lung airways, medicine.anatomical_structure, Mucociliary Clearance, Anesthesia, Ex vivo

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e4ea09a53cffd08add5292c90b744bfTest
https://doi.org/10.1016/j.etap.2013.02.002Test

المؤلفون: Clive James Gregory, Olabode B. Aleshinloye, Adriana Ratier-Cruz, Rafael Martínez-Girón, Hugo Cornelis van Woerden, Ian Price Matthews

المصدر: Respiratory Medicine. 105:877-884

مصطلحات موضوعية: Adult, Male, Pulmonary and Respiratory Medicine, Respiratory tract infections, Staining technique, Bronchial Provocation Tests, Surveys and Questionnaires, parasitic diseases, medicine, Animals, Humans, Protozoa, Asthma, Protozoan Infections, biology, business.industry, Inhaler, Respiratory disease, Sputum, Case-control study, Middle Aged, biology.organism_classification, medicine.disease, Case-Control Studies, Immunology, Housing, Female, medicine.symptom, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82cf202f73e33945417bc623121a5a13Test
https://doi.org/10.1016/j.rmed.2010.11.016Test

المؤلفون: John F. Tallman, Geoff White, Matt Crago, Lu Marshall, James V. Cassella, Pamela Albaugh, James Gregory, Dorothy W. Gallagher, Hutchison Alan J, Phil C. Ross

المصدر: Journal of medicinal chemistry. 45(23)

مصطلحات موضوعية: Male, medicine.drug_class, Stereochemistry, Allosteric regulation, Pyrimidinones, In Vitro Techniques, Motor Activity, Ligands, Chemical synthesis, Partial agonist, Binding, Competitive, Rats, Sprague-Dawley, Radioligand Assay, Structure-Activity Relationship, Xenopus laevis, In vivo, Drug Discovery, Functional selectivity, medicine, Animals, Receptor, GABA Agonists, Cerebral Cortex, Benzodiazepine, Chemistry, GABAA receptor, Imidazoles, Receptors, GABA-A, Rats, Electrophysiology, Oocytes, Molecular Medicine

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04641cdecffd8a06d387d6a2237e6fb3Test
https://pubmed.ncbi.nlm.nih.gov/12408715Test

المؤلفون: Kate J. Claycombe, Jay Whelan, Stephen J. Demichele, Gary T. Smith, Timothy James Gregory, Peter Mancuso, Julie A. Guszcza, Carolyn C. Snider, Michael D. Karlstad

المصدر: Critical care medicine. 25(3)

مصطلحات موضوعية: Male, medicine.medical_specialty, Drug Evaluation, Preclinical, Lung injury, Biology, Critical Care and Intensive Care Medicine, Capillary Permeability, chemistry.chemical_compound, Random Allocation, Double-Blind Method, Internal medicine, Macrophages, Alveolar, medicine, Animals, gamma-Linolenic acid, gamma-Linolenic Acid, Lung, Respiratory Distress Syndrome, Rats, Inbred Strains, Fish oil, Eicosapentaenoic acid, Endotoxemia, Rats, Disease Models, Animal, Endocrinology, Biochemistry, chemistry, Eicosapentaenoic Acid, Docosahexaenoic acid, Arachidonic acid, Docosapentaenoic acid, Corn oil

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20db78c43c699d960750d4770aff3c7aTest
https://pubmed.ncbi.nlm.nih.gov/9118672Test