المؤلفون: Li An Chu, Manohar Prasad Koduri, Venkanagouda S. Goudar, Fan-Gang Tseng, Long Sheng Lu, Yunching Chen, Yen Nhi Ngoc Ta

المصدر: ACS Applied Materials & Interfaces. 13:48478-48491

مصطلحات موضوعية: Materials science, Pyridines, Antineoplastic Agents, Context (language use), Poloxamer, Collagen Type I, Transforming Growth Factor beta1, Extracellular matrix, Mice, chemistry.chemical_compound, Paracrine signalling, Spheroids, Cellular, Regorafenib, Collagen network, Tumor Microenvironment, Animals, Humans, Benzopyrans, Cell Culture Techniques, Three Dimensional, General Materials Science, Tumor microenvironment, Phenylurea Compounds, Spheroid, Coculture Techniques, chemistry, Cancer cell, NIH 3T3 Cells, Cancer research, Fluorouracil, Colorectal Neoplasms

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d5e983f4a6b9210fa3b902b72d56266Test
https://doi.org/10.1021/acsami.1c18249Test

المؤلفون: Pei Ru Jin, Yi Chiung Hsu, Mei Ren Wang, Charles P. Lai, Anthony Yan-Tang Wu, Jane Wang, Fu Fei Hsu, Yunching Chen, Dong Yu Gao, Pei Lun Yu, John Jun Sheng Ko, Tsai-Te Lu, Chu Chi Lin, Li An Chu, Chih-Chun Chang, Jiantai Timothy Qiu, Yun Chieh Sung, Fu Nien Wang, Ann-Shyn Chiang, Show-Jen Chiou, Yu Sing Chen

المصدر: Nature Nanotechnology. 14:1160-1169

مصطلحات موضوعية: Male, Carcinoma, Hepatocellular, Angiogenesis, medicine.medical_treatment, Biomedical Engineering, Bioengineering, 02 engineering and technology, Nitric Oxide, 010402 general chemistry, 01 natural sciences, Nitric oxide, Neovascularization, Mice, chemistry.chemical_compound, Immune system, Adjuvants, Immunologic, Tumor Microenvironment, Animals, Humans, Medicine, General Materials Science, Electrical and Electronic Engineering, Neovascularization, Pathologic, business.industry, Liver Neoplasms, Cancer, Immunotherapy, 021001 nanoscience & nanotechnology, Condensed Matter Physics, medicine.disease, Atomic and Molecular Physics, and Optics, 0104 chemical sciences, chemistry, Delayed-Action Preparations, Cancer research, Nanoparticles, Cancer vaccine, Nanocarriers, medicine.symptom, 0210 nano-technology, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fbc6a29960fc5dc8726b07945d24e3fcTest
https://doi.org/10.1038/s41565-019-0570-3Test

المؤلفون: Chia-Lung Tsai, Shao-Feng Huang, Yun-Chieh Sung, Sheng-Kai Wang, Kuan-Wei Huang, Guann-Jen Chern, Rui-Lin Huang, Yu-Tsung Lai, Cheng-Chin Chiang, Ting-Yun Shiue, Yunching Chen, Ting-Lun Ho, Pi-Bei Hwang

المصدر: Biomacromolecules. 19:2330-2339

مصطلحات موضوعية: 0301 basic medicine, Small interfering RNA, Carcinoma, Hepatocellular, Polymers and Plastics, Aptamer, Bioengineering, Asialoglycoprotein Receptor, 010402 general chemistry, 01 natural sciences, Biomaterials, Mice, 03 medical and health sciences, chemistry.chemical_compound, Drug Delivery Systems, In vivo, Tumor Microenvironment, Materials Chemistry, medicine, Animals, RNA, Small Interfering, Tumor microenvironment, Liver Neoplasms, Galactose, medicine.disease, Galactoside, digestive system diseases, In vitro, Neoplasm Proteins, 0104 chemical sciences, 030104 developmental biology, chemistry, Cancer research, Nanoparticles, Asialoglycoprotein receptor, Liver cancer

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c73ea5424d03a2f7397133165236a1deTest
https://doi.org/10.1021/acs.biomac.8b00358Test

المؤلفون: Chun Hung Liu, Jia-Yu Liu, Kun-Ming Chan, Guann-Gen Chern, Yu-Hsuan Wu, Tsaiyu Chiang, Fu-Fei Hsu, Ya-Chi Liu, Yunching Chen

المصدر: Molecular Pharmaceutics. 13:2253-2262

مصطلحات موضوعية: Liver Cirrhosis, Male, Vascular Endothelial Growth Factor A, 0301 basic medicine, Benzylamines, Receptors, CXCR4, Pathology, medicine.medical_specialty, Small interfering RNA, Carcinoma, Hepatocellular, Cirrhosis, Angiogenesis, Pharmaceutical Science, Angiogenesis Inhibitors, Inflammation, Cyclams, Mice, 03 medical and health sciences, chemistry.chemical_compound, Heterocyclic Compounds, Fibrosis, Drug Discovery, Hepatic Stellate Cells, medicine, Animals, Humans, RNA, Small Interfering, Carbon Tetrachloride, Mice, Inbred C3H, CXCR4 antagonist, Neovascularization, Pathologic, business.industry, Liver Neoplasms, medicine.disease, Vascular endothelial growth factor, Disease Models, Animal, 030104 developmental biology, Liver, chemistry, Disease Progression, Hepatic stellate cell, Cancer research, Nanoparticles, Molecular Medicine, medicine.symptom, business, Signal Transduction

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4c636247d15fa2f4d8df756de21bdb0Test
https://doi.org/10.1021/acs.molpharmaceut.5b00913Test

المؤلفون: Dehui Wan, Dong-Yu Gao, Ts-Ting Lin, Ya-Chi Liu, Tsaiyu Chiang, Yunching Chen, Jia-Yu Liu, Liying Wang, Yun-Chieh Sung

المصدر: Journal of Controlled Release. 221:62-70

مصطلحات موضوعية: Liver Cirrhosis, Male, Niacinamide, 0301 basic medicine, Sorafenib, medicine.drug_class, Pharmaceutical Science, macromolecular substances, 02 engineering and technology, Pharmacology, Tyrosine-kinase inhibitor, Polyethylene Glycols, Mice, 03 medical and health sciences, chemistry.chemical_compound, Polylactic Acid-Polyglycolic Acid Copolymer, Fibrosis, Human Umbilical Vein Endothelial Cells, medicine, Animals, Lactic Acid, Carbon Tetrachloride, Polyglactin 910, Protein Kinase Inhibitors, Drug Carriers, Chemistry, Phenylurea Compounds, technology, industry, and agriculture, 021001 nanoscience & nanotechnology, medicine.disease, Lactic acid, PLGA, 030104 developmental biology, Liver, Carbon tetrachloride, Systemic administration, Nanoparticles, 0210 nano-technology, Drug carrier, Polyglycolic Acid, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a986f3833ace7c8f97839c7a617df38Test
https://doi.org/10.1016/j.jconrel.2015.11.003Test

المؤلفون: Chun Hung Liu, Annique M M J Duyverman, Shuji Kitahara, Dan G. Duda, Kuo Shyang Jeng, Chiung Fang Chang, Yun Chieh Sung, Rakesh R. Ramjiawan, Chih-Chun Chang, Ya Chi Liu, Simona Dima, Rakesh K. Jain, Peigen Huang, Andrew X. Zhu, Dong Yu Gao, Keith T. Flaherty, Irinel Popescu, Fu Fei Hsu, Yunching Chen, Cyril H. Benes, Nabeel Bardeesy, Ts Ting Lin

المساهمون: Medical oncology laboratory, CCA - Cancer Treatment and quality of life

المصدر: Scientific Reports
Chen, Y, Liu, Y C, Sung, Y C, Ramjiawan, R R, Lin, T T, Chang, C C, Jeng, K S, Chang, C F, Liu, C H, Gao, D Y, Hsu, F F, Duyverman, A M, Kitahara, S, Huang, P, Dima, S, Popescu, I, Flaherty, K T, Zhu, A X, Bardeesy, N, Jain, R K, Benes, C H & Duda, D G 2017, ' Overcoming sorafenib evasion in hepatocellular carcinoma using CXCR4-targeted nanoparticles to co-deliver MEK-inhibitors ', Scientific Reports, vol. 7, 44123 . https://doi.org/10.1038/srep44123Test
Scientific Reports, 7:44123. Nature Publishing Group

مصطلحات موضوعية: 0301 basic medicine, Oncology, Sorafenib, MAPK/ERK pathway, Niacinamide, medicine.medical_specialty, Receptors, CXCR4, Carcinoma, Hepatocellular, Article, Cell Line, 03 medical and health sciences, Transactivation, Mice, 0302 clinical medicine, Drug Delivery Systems, Downregulation and upregulation, Internal medicine, medicine, Animals, Humans, Protein kinase A, neoplasms, Protein Kinase Inhibitors, Multidisciplinary, Chemistry, Phenylurea Compounds, Liver Neoplasms, HCCS, digestive system diseases, 3. Good health, Neoplasm Proteins, 030104 developmental biology, Apoptosis, 030220 oncology & carcinogenesis, Cancer cell, Cancer research, Nanoparticles, Benzimidazoles, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2799de176d31e563df78ee2e4c56f53cTest
https://pubmed.ncbi.nlm.nih.gov/28276530Test

المؤلفون: Chien-Wen Chang, Chen-Hsiang Kuan, Yunching Chen, Chun-Jui Lin, Li-Wen Wang, Rih-Yang Huang, Hsi-Chin Wu, Tzu-Wei Wang

المصدر: Biomaterials. 90

مصطلحات موضوعية: Materials science, Biophysics, Cystamine, Bioengineering, Peptide, 02 engineering and technology, Nanoconjugates, 010402 general chemistry, 01 natural sciences, Dithiothreitol, Theranostic Nanomedicine, Biomaterials, chemistry.chemical_compound, Mice, Drug Delivery Systems, Cell Line, Tumor, medicine, Animals, Humans, Doxorubicin, Hyaluronic Acid, chemistry.chemical_classification, Ovarian Neoplasms, Antibiotics, Antineoplastic, Ovary, Hydrogen-Ion Concentration, 021001 nanoscience & nanotechnology, Controlled release, 0104 chemical sciences, chemistry, Mechanics of Materials, Delayed-Action Preparations, Drug delivery, Ceramics and Composites, Female, 0210 nano-technology, Drug carrier, Peptides, Oxidation-Reduction, Conjugate, Biomedical engineering, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff9ae2f926cc3d3f693b88d925c1ce31Test
https://pubmed.ncbi.nlm.nih.gov/26974704Test

المؤلفون: Chih-Chun Chang, Dong-Yu Gao, Jia-Yu Liu, Yunching Chen, Ya Chi Liu, Ts-Ting Lin, Yun-Chieh Sung, Wen-Hsuan Chiang

المصدر: Biomaterials. 67

مصطلحات موضوعية: Sorafenib, Male, Niacinamide, Receptors, CXCR4, Carcinoma, Hepatocellular, Angiogenesis, Biophysics, Bioengineering, Pharmacology, Biomaterials, chemistry.chemical_compound, Mice, Drug Delivery Systems, Polylactic Acid-Polyglycolic Acid Copolymer, Cell Line, Tumor, medicine, Human Umbilical Vein Endothelial Cells, Tumor Microenvironment, Animals, Humans, Lactic Acid, Neoplasm Metastasis, neoplasms, Cell Proliferation, Tumor microenvironment, CXCR4 antagonist, Cell Death, business.industry, Phenylurea Compounds, Liver Neoplasms, medicine.disease, Lipids, Survival Analysis, digestive system diseases, Endocytosis, PLGA, Phenotype, chemistry, Mechanics of Materials, Tumor progression, Drug Resistance, Neoplasm, Hepatocellular carcinoma, Ceramics and Composites, Nanoparticles, Liver cancer, business, Polyglycolic Acid, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a899a76c3a1e02636fb1703049c9816Test
https://pubmed.ncbi.nlm.nih.gov/26218745Test

المؤلفون: Dong Yu Gao, Tsaiyu Chiang, Jia Yu Liu, Guann Gen Chern, Ts Ting Lin, Chun Hung Liu, Yunching Chen

المصدر: Molecular therapy : the journal of the American Society of Gene Therapy. 23(11)

مصطلحات موضوعية: Sorafenib, Male, Niacinamide, Vascular Endothelial Growth Factor A, Small interfering RNA, Benzylamines, Receptors, CXCR4, Carcinoma, Hepatocellular, Angiogenesis Inhibitors, Pharmacology, Cyclams, chemistry.chemical_compound, Mice, In vivo, Heterocyclic Compounds, Cell Line, Tumor, Drug Discovery, Genetics, Tumor Microenvironment, Medicine, Animals, Humans, RNA, Small Interfering, Molecular Biology, Tumor microenvironment, Mice, Inbred C3H, CXCR4 antagonist, Neovascularization, Pathologic, business.industry, Phenylurea Compounds, Liver Neoplasms, Genetic Therapy, medicine.disease, digestive system diseases, Chemokine CXCL12, Vascular endothelial growth factor, chemistry, Tumor progression, Disease Progression, Molecular Medicine, Nanoparticles, Original Article, business, Liver cancer, medicine.drug, Signal Transduction

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3651a5253b44bf258bfcad46bd4e3d8eTest
https://pubmed.ncbi.nlm.nih.gov/26278330Test

المؤلفون: Leaf Huang, Qi Yang, Yunching Chen, Surendar Reddy Bathula

المصدر: J Invest Dermatol

مصطلحات موضوعية: Small interfering RNA, Skin Neoplasms, Genes, myc, Apoptosis, Dermatology, Biochemistry, Article, Fatty Acids, Monounsaturated, 03 medical and health sciences, chemistry.chemical_compound, Mice, 0302 clinical medicine, Cell Line, Tumor, Medicine, Animals, Humans, RNA, Small Interfering, Molecular Biology, neoplasms, Melanoma, 030304 developmental biology, chemistry.chemical_classification, 0303 health sciences, Reactive oxygen species, business.industry, RNA, Cancer, Cell Biology, Genetic Therapy, medicine.disease, 3. Good health, Mice, Inbred C57BL, Quaternary Ammonium Compounds, chemistry, Paclitaxel, Cell culture, 030220 oncology & carcinogenesis, Immunology, Liposomes, Cancer research, Nanoparticles, Female, business, Signal Transduction

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c85693cd0285d0def66d6e702e7c0003Test
https://pubmed.ncbi.nlm.nih.gov/21068733Test