Roles of Ubiquitination and SUMOylation in the Regulation of Angiogenesis
| العنوان: | Roles of Ubiquitination and SUMOylation in the Regulation of Angiogenesis |
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| المؤلفون: | Pier Paolo Scaglioni, Andrea Rabellino, Cristina Andreani |
| المصدر: | Current Issues in Molecular Biology Volume 35 Issue 1 Pages 109-126 |
| بيانات النشر: | Multidisciplinary Digital Publishing Institute, 2019. |
| سنة النشر: | 2019 |
| مصطلحات موضوعية: | 0301 basic medicine, Angiogenesis, SUMO protein, Neovascularization, Physiologic, Biology, Neovascularization, 03 medical and health sciences, Roles, 0302 clinical medicine, Ubiquitin, medicine, Animals, Humans, Phosphorylation, Receptor, Neovascularization, Pathologic, Receptors, Notch, Mechanism (biology), Ubiquitination, Endothelial Cells, General Medicine, SUMOylation, Cell biology, 030104 developmental biology, Receptors, Vascular Endothelial Growth Factor, 030220 oncology & carcinogenesis, Protein processing, biology.protein, medicine.symptom, Protein Processing, Post-Translational, Signal Transduction, Regulation |
| الوصف: | The generation of new blood vessels from the existing vasculature is a dynamic and complex mechanism known as angiogenesis. Angiogenesis occurs during the entire lifespan of vertebrates and participates in many physiological processes. Furthermore, angiogenesis is also actively involved in many human diseases and disorders, including cancer, obesity and infections. Several inter-connected molecular pathways regulate angiogenesis, and post-translational modifications, such as phosphorylation, ubiquitination and SUMOylation, tightly regulate these mechanisms and play a key role in the control of the process. Here, we describe in detail the roles of ubiquitination and SUMOylation in the regulation of angiogenesis. |
| وصف الملف: | application/pdf |
| اللغة: | English |
| تدمد: | 1467-3045 |
| DOI: | 10.21775/cimb.035.109 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32a8bb3309ac8d072dfd9aa7097da233Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....32a8bb3309ac8d072dfd9aa7097da233 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 14673045 |
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| DOI: | 10.21775/cimb.035.109 |