نتائج البحث - "Nardone A."

1

The oral selective oestrogen receptor degrader (SERD) AZD9496 is comparable to fulvestrant in antagonising ER and circumventing endocrine resistance

المؤلفون: Agostina Nardone, Rachel Schiff, Henry Brown, Meghana V. Trivedi, Martin Shea, Mark Pilling, Jamunarani Veeraraghavan, Chandandeep Nagi, Rinath Jeselsohn, Carmine De Angelis, Oona Delpuech, Maria Letizia Cataldo, Tamika Mitchell, C. Kent Osborne, Mothaffar F. Rimawi, Hazel M. Weir, Gary C. Chamness, Xiaoyong Fu, Susan G. Hilsenbeck

المساهمون: Pilling, Mark [0000-0002-7446-6597], Apollo - University of Cambridge Repository, Nardone, A., Weir, H., Delpuech, O., Brown, H., De Angelis, C., Cataldo, M. L., Fu, X., Shea, M. J., Mitchell, T., Veeraraghavan, J., Nagi, C., Pilling, M., Rimawi, M. F., Trivedi, M., Hilsenbeck, S. G., Chamness, G. C., Jeselsohn, R., Osborne, C. K., Schiff, R.

المصدر: British Journal of Cancer

مصطلحات موضوعية: Cancer Research, Indoles, Neoplasms, Hormone-Dependent, Breast Neoplasms, Article, 03 medical and health sciences, chemistry.chemical_compound, Mice, MCF-7 Cell, 0302 clinical medicine, Breast cancer, Cinnamate, In vivo, medicine, Animals, Humans, Receptor, skin and connective tissue diseases, Fulvestrant, Cancer, Cell Proliferation, Estradiol, Animal, Cell growth, Estrogens, medicine.disease, Estrogen, Metastatic breast cancer, 3. Good health, Tamoxifen, Oncology, chemistry, Receptors, Estrogen, Indole, Cell culture, Cinnamates, Drug Resistance, Neoplasm, 030220 oncology & carcinogenesis, Cancer research, MCF-7 Cells, Heterografts, Female, Growth inhibition, Heterograft, Breast Neoplasm, Human, medicine.drug

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1307add3c66d5075ec69b579adb4aedTest
http://europepmc.org/articles/PMC6353941Test

2

Real-time cholesterol sorting in Plasmodium falciparum-erythrocytes as revealed by 3D label-free imaging

المؤلفون: Kentaro Yamaguchi, Eri H. Hayakawa, Glenn Nardone, Masahiro Mori

المصدر: Scientific Reports, Vol 10, Iss 1, Pp 1-12 (2020)
Scientific Reports

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6cee8c6d0cb9e8c1f88f4c71cf68ded6Test
http://link.springer.comTest/article/10.1038/s41598-020-59552-9

3

Integrated analysis of sialotranscriptome and sialoproteome of the brown dog tick Rhipicephalus sanguineus (s.l.): Insights into gene expression during blood feeding

المؤلفون: Itabajara da Silva Vaz, José M. C. Ribeiro, Motoshi Suzuki, Eric Calvo, Lucía Sánchez Di Maggio, Gabriela Alves Sabadin, Stephen Lu, Glenn Nardone, Lucas Tirloni

المصدر: J Proteomics

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e365ecc510fa1da0325f8aa51a17556Test
https://pubmed.ncbi.nlm.nih.gov/32673754Test

4

Upregulation of ER Signaling as an Adaptive Mechanism of Cell Survival in HER2-Positive Breast Tumors Treated with Anti-HER2 Therapy

المساهمون: Giuliano, Mario, Hu, H, Wang, Yc, Fu, X, Nardone, Agostina, Herrera, S, Mao, S, Contreras, A, Gutierrez, C, Wang, T, Hilsenbeck, Sg, DE ANGELIS, Carmine, Wang, Nj, Heiser, Lm, Gray, Jw, Lopez Tarruella, S, Pavlick, Ac, Trivedi, Mv, Chamness, Gc, Chang, Jc, Osborne, Ck, Rimawi, Mf, Schiff, R.

المصدر: Repositorio Institucional de la Consejería de Sanidad de la Comunidad de Madrid
Consejería de Sanidad de la Comunidad de Madrid

مصطلحات موضوعية: Cancer Research, medicine.medical_specialty, Time Factors, Antineoplastic Agents, Hormonal, Cell Survival, Receptor, ErbB-2, medicine.medical_treatment, Gene Expression, Estrogen receptor, Breast Neoplasms, Lapatinib, Article, Mice, Downregulation and upregulation, Cell Line, Tumor, Internal medicine, Animals, Humans, Medicine, Molecular Targeted Therapy, Epidermal growth factor receptor, skin and connective tissue diseases, neoplasms, Neoadjuvant therapy, biology, Fulvestrant, business.industry, Cancer, medicine.disease, Xenograft Model Antitumor Assays, Neoadjuvant Therapy, Disease Models, Animal, Endocrinology, Proto-Oncogene Proteins c-bcl-2, Receptors, Estrogen, Oncology, Drug Resistance, Neoplasm, Tumor progression, Quinazolines, Cancer research, biology.protein, Female, Receptors, Progesterone, business, Biomarkers, Signal Transduction, medicine.drug

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4b1598f486d1beb5e4551a1d1f12f3dTest
https://doi.org/10.1158/1078-0432.ccr-14-2728Test

5

Target highlights from the first post-PSI CASP experiment (CASP12, May-August 2016)

المساهمون: Genome Center [UC Davis], University of California [Davis] (UC Davis), University of California-University of California, Abteilung Membranbiochemie [Martinsried], Max-Planck-Institut für Biochemie (MPIB), Max-Planck-Gesellschaft-Max-Planck-Gesellschaft, Institute for Cell and Molecular Biosciences, Newcastle University [Newcastle], Interdisciplinary Centre of Research in Animal Health, Faculdade de Medicina Veterinária, Pólo Universitário do Alto da Ajuda, Universidade de Lisboa, Oxford Glycobiol Inst, Dept Biochem, University of Oxford [Oxford], Unidade de Ciencias Biomoleculares Aplicadas (UCIBIO), Requimte, Departamento de Química (DQ), Faculdade de Ciências e Tecnologia = School of Science & Technology (FCT NOVA), Universidade Nova de Lisboa = NOVA University Lisbon (NOVA)-Universidade Nova de Lisboa = NOVA University Lisbon (NOVA)-Faculdade de Ciências e Tecnologia = School of Science & Technology (FCT NOVA), Universidade Nova de Lisboa = NOVA University Lisbon (NOVA)-Universidade Nova de Lisboa = NOVA University Lisbon (NOVA)-Universidade do Porto-Departamento de Química (DQ), Universidade Nova de Lisboa = NOVA University Lisbon (NOVA)-Universidade Nova de Lisboa = NOVA University Lisbon (NOVA)-Universidade do Porto, Dept Mol Cellular & Dev Biol, University of California [Santa Barbara] (UCSB), Structural Biology Center, Biosciences Division, Universität des Saarlandes [Saarbrücken], Department of Chemistry, University of Copenhagenn, Department of Cell Biology and Molecular Genetics, University of Maryland [College Park], University of Maryland System-University of Maryland System, Department of Biomolecular Sciences and Biotechnology, University of Milano, Biological Solid-State NMR Methods - Méthodes de RMN à l'état solide en biologie, Institut des Sciences Analytiques (ISA), Institut de Chimie du CNRS (INC)-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Centre National de la Recherche Scientifique (CNRS)-Institut de Chimie du CNRS (INC)-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Centre National de la Recherche Scientifique (CNRS), Biomedical Research & Study Centre, Department of Biochemistry [Oxford], Biozentrum [Basel, Suisse], University of Basel (Unibas), Kryshtafovych, A, Albrecht, R, Baslé, A, Bule, P, Caputo, A, Carvalho, A, Chao, K, Diskin, R, Fidelis, K, Fontes, C, Fredslund, F, Gilbert, H, Goulding, C, Hartmann, M, Hayes, C, Herzberg, O, Hill, J, Joachimiak, A, Kohring, G, Koning, R, Lo Leggio, L, Mangiagalli, M, Michalska, K, Moult, J, Najmudin, S, Nardini, M, Nardone, V, Ndeh, D, Nguyen, T, Pintacuda, G, Postel, S, Van Raaij, M, Roversi, P, Shimon, A, Singh, A, Sundberg, E, Tars, K, Zitzmann, N, Schwede, T

المصدر: Proteins, vol 86 Suppl 1, iss Suppl 1
Proteins-Structure, Function and Bioinformatics
Proteins-Structure, Function and Bioinformatics, Wiley, 2018, 86, pp.27-50. ⟨10.1002/prot.25392⟩

مصطلحات موضوعية: 0301 basic medicine, Models, Molecular, Protein Folding, Protein Conformation, Bioinformatics, FIS/07 - FISICA APPLICATA (A BENI CULTURALI, AMBIENTALI, BIOLOGIA E MEDICINA), Computational biology, computer.software_genre, Crystallography, X-Ray, Biochemistry, Article, Mathematical Sciences, 03 medical and health sciences, Structural Biology, Models, Information and Computing Sciences, [CHIM]Chemical Sciences, Animals, Humans, [SDV.BBM]Life Sciences [q-bio]/Biochemistry, Molecular Biology, CASP, Molecular Biology, X-ray crystallography, Physics, Crystallography, Bacteria, Proteins, Computational Biology, Molecular, Protein structure prediction, Biological Sciences, BIO/10 - BIOCHIMICA, NMR, protein structure prediction, 030104 developmental biology, Biological significance, X-Ray, Data mining, computer, Software

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2375c05a4f68a2d15edec25c29dd5e2fTest
https://escholarship.org/uc/item/21s8k249Test

6

Restored iron transport by a small molecule promotes absorption and hemoglobinization in animals

المصدر: Science. 356:608-616

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a4ad378d8c7997f59df6b6b9d64557eTest
https://doi.org/10.1126/science.aah3862Test

7

Gasdermin pores permeabilize mitochondria to augment caspase-3 activation during apoptosis and inflammasome activation

المؤلفون: Corey, Rogers, Dan A, Erkes, Alexandria, Nardone, Andrew E, Aplin, Teresa, Fernandes-Alnemri, Emad S, Alnemri

المصدر: Nature Communications

مصطلحات موضوعية: Mice, Knockout, Threonine, Skin Neoplasms, Caspase 3, Inflammasomes, Macrophages, Primary Cell Culture, Melanoma, Experimental, Cytochromes c, Fibroblasts, Article, Mitochondria, Mice, Inbred C57BL, Gene Knockout Techniques, Mice, HEK293 Cells, Protein Domains, Receptors, Estrogen, Mitochondrial Membranes, Mutation, Pyroptosis, Animals, Humans, Phosphorylation, HeLa Cells

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=pmid________::0371049dbbeb2930a1a71b419de79155Test
https://pubmed.ncbi.nlm.nih.gov/30976076Test

8

HER2 Reactivation through Acquisition of the HER2 L755S Mutation as a Mechanism of Acquired Resistance to HER2-targeted Therapy in HER2+ Breast Cancer

المساهمون: Xu, X., De Angelis, C., Burke, K. A., Nardone, A., Hu, H., Qin, L., Veeraraghavan, J., Sethunath, V., Heiser, L. M., Wang, N., Ng, C. K. Y., Chen, E. S., Renwick, A., Wang, T., Nanda, S., Shea, M., Mitchell, T., Rajendran, M., Waters, I., Zabransky, D. J., Scott, K. L., Gutierrez, C., Nagi, C., Geyer, F. C., Chamness, G. C., Park, B. H., Shaw, C. A., Hilsenbeck, S. G., Rimawi, M. F., Gray, J. W., Weigelt, B., Reis-Filho, J. S., Osborne, C. K., Schiff, R.

مصطلحات موضوعية: 0301 basic medicine, Cancer Research, Xenograft Model Antitumor Assay, Receptor, ErbB-2, Afatinib, medicine.medical_treatment, Breast Neoplasms, Biology, Lapatinib, Antibodies, Monoclonal, Humanized, Article, Targeted therapy, 03 medical and health sciences, Mice, 0302 clinical medicine, Germline mutation, Breast cancer, Trastuzumab, Cell Line, Tumor, medicine, Animals, Humans, Molecular Targeted Therapy, skin and connective tissue diseases, Cell Proliferation, Animal, Cancer, Quinazoline, medicine.disease, Xenograft Model Antitumor Assays, 030104 developmental biology, Oncology, Receptors, Estrogen, Drug Resistance, Neoplasm, 030220 oncology & carcinogenesis, Immunology, Neratinib, Mutation, Cancer research, Quinazolines, Female, Breast Neoplasm, medicine.drug, Human, Signal Transduction

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6cb068280b301594f2965d31acd31789Test
https://europepmc.org/articles/PMC5762201Test/

9

Structure and Ligand-Binding Mechanism of a Cysteinyl Leukotriene-Binding Protein from a Blood-Feeding Disease Vector

المؤلفون: Georgia C. Atella, John F. Andersen, Apostolos G. Gittis, José M. C. Ribeiro, Lívia Silva-Cardoso, Van N. Pham, Willy Jablonka, Glenn Nardone

المصدر: ACS Chemical Biology. 11:1934-1944

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::418e8d174933d2a62137de180bb7be36Test
https://doi.org/10.1021/acschembio.6b00032Test

10

Homeotic Arm-to-Leg Transformation Associated with Genomic Rearrangements at the PITX1 Locus

المؤلفون: Katarina Dathe, Anna Maria Nardone, Silke Lohan, Jochen Hecht, Danny Chan, Daniel M. Ibrahim, Eva Klopocki, Ulrich Mennen, Stefan Mundlos, Peter N. Robinson, Martin Franke, Francesco Brancati, Peter Krawitz, Malte Spielmann, Lars Wittler, Bernd Timmermann, A. Landi, Paola Ferrari

المصدر: American Journal of Human Genetics

مصطلحات موضوعية: Male, Wrist Joint, ved/biology.organism_classification_rank.species, Mice, Transgenic, Biology, Article, Translocation, Genetic, Fingers, Mice, Transformation, Genetic, Elbow Joint, medicine, Genetics, Animals, Humans, Paired Box Transcription Factors, Genetic Predisposition to Disease, Genetics(clinical), Enhancer, Model organism, Genetics (clinical), Carpal Bones, Gene Rearrangement, Comparative Genomic Hybridization, ved/biology, Genome, Human, Brachydactyly, Genes, Homeobox, Liebenberg syndrome, Gene Expression Regulation, Developmental, Gene rearrangement, Sequence Analysis, DNA, medicine.disease, Phenotype, Synostosis, Genetic Loci, Female, Homeotic gene, Developmental biology, Hand Deformities, Congenital, Gene Deletion, Comparative genomic hybridization

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7626a1d6d794673f84386d296a3879f4Test

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