دورية أكاديمية
A perspective on muscle phenotyping in musculoskeletal research.
| العنوان: | A perspective on muscle phenotyping in musculoskeletal research. |
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| المؤلفون: | Foessl, Ines, Ackert-Bicknell, Cheryl L, Kague, Erika, Laskou, Faidra, Jakob, Franz, Karasik, David, Obermayer-Pietsch, Barbara, Alonso, Nerea, Bjørnerem, Åshild, Brandi, Maria Luisa, Busse, Björn, Calado, Ângelo, Cebi, Alper Han, Christou, Maria, Curran, Kathleen M, Hald, Jannie Dahl, Semeraro, Maria Donatella, Douni, Eleni, Duncan, Emma L, Duran, Ivan, Formosa, Melissa M, Gabet, Yankel, Ghatan, Samuel, Gkitakou, Artemis, Hassler, Eva Maria, Högler, Wolfgang, Heino, Terhi J, Hendrickx, Gretl, Khashayar, Patricia, Kiel, Douglas P, Koromani, Fjorda, Langdahl, Bente, Lopes, Philippe, Mäkitie, Outi, Maurizi, Antonio, Medina-Gomez, Carolina, Ntzani, Evangelia, Ohlsson, Claes, Prijatelj, Vid, Rabionet, Raquel, Reppe, Sjur, Rivadeneira, Fernando, Roshchupkin, Gennady, Sharma, Neha, Søe, Kent, Styrkarsdottir, Unnur, Szulc, Pavel, Teti, Anna, Tobias, Jon, Valjevac, Amina, van de Peppel, Jeroen, van der Eerden, Bram, van Rietbergen, Bert, Zekic, Tatjana, Zillikens, M Carola |
| المصدر: | Trends Endocrinol Metab ; ISSN:1879-3061 ; Volume:35 ; Issue:6 |
| بيانات النشر: | Elsevier Science |
| سنة النشر: | 2024 |
| المجموعة: | PubMed Central (PMC) |
| مصطلحات موضوعية: | animal models, muscle, musculoskeletal phenotyping, sarcopenia |
| الوصف: | Musculoskeletal research should synergistically investigate bone and muscle to inform approaches for maintaining mobility and to avoid bone fractures. The relationship between sarcopenia and osteoporosis, integrated in the term 'osteosarcopenia', is underscored by the close association shown between these two conditions in many studies, whereby one entity emerges as a predictor of the other. In a recent workshop of Working Group (WG) 2 of the EU Cooperation in Science and Technology (COST) Action 'Genomics of MusculoSkeletal traits Translational Network' (GEMSTONE) consortium (CA18139), muscle characterization was highlighted as being important, but currently under-recognized in the musculoskeletal field. Here, we summarize the opinions of the Consortium and research questions around translational and clinical musculoskeletal research, discussing muscle phenotyping in human experimental research and in two animal models: zebrafish and mouse. |
| نوع الوثيقة: | article in journal/newspaper review |
| اللغة: | English |
| العلاقة: | https://doi.org/10.1016/j.tem.2024.01.004Test; https://pubmed.ncbi.nlm.nih.gov/38553405Test |
| DOI: | 10.1016/j.tem.2024.01.004 |
| الإتاحة: | https://doi.org/10.1016/j.tem.2024.01.004Test https://pubmed.ncbi.nlm.nih.gov/38553405Test |
| حقوق: | Crown Copyright © 2024. Published by Elsevier Ltd. All rights reserved. |
| رقم الانضمام: | edsbas.18AC9FE |
| قاعدة البيانات: | BASE |
| DOI: | 10.1016/j.tem.2024.01.004 |
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