-
1
المؤلفون: Cornacchia, C., Marinelli, L., Di Rienzo, A., Dimmito, M. P., Serra, F., Di Biase, G., De Filippis, B., Turkez, H., Mardinoglu, Adil, Bellezza, I., Di Stefano, A., Cacciatore, I.
المصدر: European Journal of Medicinal Chemistry. 243
مصطلحات موضوعية: Antioxidant, Blood brain shuttle, Brain delivery system, Diketopiperazine, Levodopa, Parkinson's disease, Animals, Antioxidants, Blood-Brain Barrier, Caco-2 Cells, Carcinoma, Renal Cell, Diketopiperazines, Humans, Kidney Neoplasms, Oxidative Stress, Parkinson Disease, Rats, 8 hydroxydeoxyguanosine, free radical, glutathione, neurotoxin, piperazinedione, reactive oxygen metabolite, transcription factor Nrf2, animal cell, animal experiment, animal model, animal tissue, Article, biomembrane, biosynthesis, blood brain barrier, brain cortex, cancer model, cell culture, cell death, comet assay, controlled study, cytotoxicity, DNA damage, genetic marker, genotoxicity, half life time, human, hydrolysis, in vitro study, intestine fluid, male, newborn, nonhuman, rat, simulation, stomach juice, total antioxidant capacity, animal, Caco-2 cell line, kidney tumor, metabolism, renal cell carcinoma
وصف الملف: print
الوصول الحر: https://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-328828Test
https://doi.org/10.1016/j.ejmech.2022.114746Test -
2دورية أكاديمية
المؤلفون: Ji, Weixiu, Wang, Linjia, He, Shiyi, Yan, Lu, Li, Tieying, Wang, Jianxiong, Kong, Ah-Ng Tony, Yu, Siwang, Zhang, Ying
مصطلحات موضوعية: hypoxia inducible factor 1alpha, small interfering RNA, transcription factor Nrf2, animal cell, antioxidant responsive element, binding affinity, C2C12 cell line, controlled study, disease duration, exposure, gene, gene activation, gene knockdown, hypoxia, male, mouse, nonhuman, protein expression, quadriceps femoris musc le, signal transduction, skeletal muscle, transgenic mouse, upregulation
وصف الملف: application/pdf
العلاقة: https://research.usq.edu.au/download/68b54f1a653161c04b5e841ac4779b9cc4b45877fcca91e45e3fbc89923b6795/2811419/2018-12%20Plos%20one%20Nrf2%20and%20hypoxia.pdfTest; https://doi.org/10.1371/journal.pone.0208474Test; Ji, Weixiu, Wang, Linjia, He, Shiyi, Yan, Lu, Li, Tieying, Wang, Jianxiong, Kong, Ah-Ng Tony, Yu, Siwang and Zhang, Ying. 2018. "Effects of acute hypoxia exposure with different durations on activation of Nrf2-ARE pathway in mouse skeletal muscle." PLoS One. 13 (12), pp. 1-15. https://doi.org/10.1371/journal.pone.0208474Test
الإتاحة: https://doi.org/10.1371/journal.pone.0208474Test
https://research.usq.edu.au/item/q4z8w/effects-of-acute-hypoxia-exposure-with-different-durations-on-activation-ofTest-nrf2-are-pathway-in-mouse-skeletal-muscle
https://research.usq.edu.au/download/68b54f1a653161c04b5e841ac4779b9cc4b45877fcca91e45e3fbc89923b6795/2811419/2018-12%20Plos%20one%20Nrf2%20and%20hypoxia.pdfTest -
3دورية أكاديمية
المؤلفون: Eleftheriadis T., Pissas G., Filippidis G., Liakopoulos V., Stefanidis I.
المصدر: Molecular Medicine Reports ; https://www.scopus.com/inward/record.uri?eid=2-s2.0-85096083124&doi=10.3892%2fmmr.2020.11679&partnerID=40&md5=ecd811bfc5f57435ee798aeedaf2b7e9Test
مصطلحات موضوعية: alpha tocopherol, aromatic hydrocarbon receptor, beta actin, caspase 3, ch 223191, cytochrome P450 1A1, extracellular superoxide dismutase, hypoxia inducible factor 1alpha, lactate dehydrogenase, malonaldehyde, reactive oxygen metabolite, roxadustat, transcription factor Nrf2, unclassified drug, 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide, Ahr protein, mouse, azo compound, basic helix loop helix transcription factor, Cyp1a1 protein, FG-4592, glycine, Hif1a protein, isoquinoline derivative, Nfe2l2 protein, oxygen, pyrazole derivative, animal cell, anoxia, Article
-
4دورية أكاديمية
المؤلفون: Eleftheriadis T., Pissas G., Nikolaou E., Filippidis G., Liakopoulos V., Stefanidis I.
المصدر: Biomedical Reports ; https://www.scopus.com/inward/record.uri?eid=2-s2.0-85087113574&doi=10.3892%2fbr.2020.1309&partnerID=40&md5=c8f27e95606467a8b78bc457d780c602Test
مصطلحات موضوعية: alpha tocopherol, antioxidant, caspase 3, extracellular superoxide dismutase, ferritin, glutathione reductase, hydrogen sulfide, lactate dehydrogenase, protein Bax, protein p53, reactive oxygen metabolite, transcription factor Nrf2, animal cell, anoxia, apoptosis, Article, cell death, cell viability, cytotoxicity, ferroptosis, kidney tubule cell, lipid peroxidation, mouse, necrosis assay, nonhuman, protein blood level, protein expression, reoxygenation, reperfusion injury, survival analysis
-
5Detection of the mechanism of immunotoxicity of cyclosporine A in murine in vitro and in vivo models
المؤلفون: Mirjam M. Schaap, E. van Someren, Peter C. J. Schmeits, Peter J.M. Hendriksen, M. Luijten, Ad A. C. M. Peijnenburg, H. van Loveren, André Boorsma
المساهمون: Promovendi ODB, Gezondheidsvoorlichting, Toxicogenomics, GezondheidsRisico Analyse en Toxicologie, RS: GROW - Oncology, RS: GROW - R3 - Innovative Cancer Diagnostics & Therapy
المصدر: Archives of Toxicology, 12, 89, 2325-2337
Archives of Toxicology, 89(12), 2325-2337
Archives of Toxicology 89 (2015) 12
Archives of Toxicology, 89(12), 2325-2337. Springerمصطلحات موضوعية: Male, Interspecies comparison, Mouse, Novel Foods & Agrochains, Health, Toxicology and Mutagenesis, RAPID - Risk Analysis for Products in Development, C57BL/6, Biomedical Innovation, Toxicology, Novel Foods & Agroketens, Jurkat cells, Interleukin 2, Unfolded protein response, Jurkat Cells, Mice, In vivo study, Life, Cytotoxic T cell, Immunotoxicity, BU Toxicology, Novel Foods & Agrochains, Splenocytes, Messenger RNA, BU Toxicology, General Medicine, Hep G2 Cells, Cell cycle, Endoplasmic Reticulum Stress, Cell biology, Up-Regulation, CTLL-2, medicine.anatomical_structure, BU Toxicologie, Novel Foods & Agroketens, Cyclosporine, Endoplasmic reticulum stress, Animal cell, Healthy Living, Immunosuppressive Agents, medicine.drug, Human, Cell type, Thymoma, Dpleen cell, BU Toxicologie, T cell, Down-Regulation, Down regulation, Biology, T lymphocyte activation, Cell Line, Thymoma cell line, Transcription factor Nrf2, Cyclosporine A, In vivo, Cell Line, Tumor, Upregulation, medicine, Animals, Humans, Animal experiment, Immune response, Transcriptomics, Protein Unfolding, HepG2 cell line, Cytotoxic T lymphocyte, Gene Expression Profiling, In vitro study, Nonhuman, Jurkat cell line, Mice, Inbred C57BL, Human cell, Cell culture, ELSS - Earth, Life and Social Sciences, Cell cycle regulation, Controlled study, Spleen, T-Lymphocytes, Cytotoxic
وصف الملف: application/octet-stream; application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5be7ec6d1a47efd3d841c0af6f5ca0a4Test
https://doi.org/10.1007/s00204-014-1365-9Test -
6Detection of the mechanism of immunotoxicity of cyclosporine A in murine in vitro and in vivo models
مصطلحات موضوعية: Interspecies comparison, Male, Mouse, Dpleen cell, C57BL/6, RAPID - Risk Analysis for Products in Development, Biomedical Innovation, Down regulation, Interleukin 2, T lymphocyte activation, Thymoma cell line, Transcription factor Nrf2, Unfolded protein response, Cyclosporine A, In vivo study, Life, Upregulation, Immunotoxicity, Splenocytes, Animal experiment, Life and Social Sciences, Immune response, Transcriptomics, Biology, HepG2 cell line, Cytotoxic T lymphocyte, Messenger RNA, In vitro study, ELSS - Earth, Nonhuman, Jurkat cell line, CTLL-2, Human cell, Endoplasmic reticulum stress, Animal cell, Cell cycle regulation, Controlled study, Healthy Living, Human
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=dris___00893::fcc084fa91e986a41972c0c90f60ed45Test
http://resolver.tudelft.nl/uuid:d5268521-be0c-474c-b932-3c9c77e83509Test -
7
المؤلفون: Jac M.M.J.G. Aarts, Yee Y. Lee-Hilz, Hester van der Woude, Ellen Kampman, Ivonne M.C.M. Rietjens, Martijn Vermeulen, Anne-Marie J. F. Boerboom, Birgit I. Bremer, Peter J. van Bladeren
المساهمون: TNO Kwaliteit van Leven
المصدر: Biochemical Pharmacology, 2, 72, 217-226
Biochemical Pharmacology, 72, 217-26
Biochemical Pharmacology, 72(2), 217-226
Biochemical Pharmacology, 72, 2, pp. 217-26
Biochemical Pharmacology 72 (2006) 2مصطلحات موضوعية: Nutrition and Disease, Mouse, Transcription, Genetic, Glutathione transferase, Response element, Screening test, antioxidant activity, Drug structure, Gene Expression, Aetiology, screening and detection [ONCOL 5], Toxicology, Chemoprophylaxis, Biochemistry, Gene, chemistry.chemical_compound, Mice, Transient transfection, Genes, Reporter, Voeding en Ziekte, Gene expression, Determinants in Health and Disease [EBP 1], Gene activation, Reduced nicotinamide adenine dinucleotide (phosphate) dehydrogenase (quinone), Luteolin, Luciferases, Regulation of gene expression, protein-kinase-c, Structure activity relation, Genetic transcription, Myricetin, Transcription initiation, Validation study, Molecular interaction, Hepa-1c1c7 cells, inducible expression, Reporter gene, Tandem repeat, consensus sequence, Enzyme Induction, transcription factor nrf2, Quercetin, Benzyl isothiocyanate, Animal cell, Plasmids, Tert butylhydroquinone, Biochemie, Gene induction, Biology, chemopreventive agents, Cell Line, Molecular epidemiology [NCEBP 1], nad(p)h-quinone oxidoreductase, Kaempferol, Cancer screening, Structure-Activity Relationship, Drug potency, Antioxidant activity, Translational research [ONCOL 3], Interventional oncology [UMCN 1.5], Cancer cell culture, Animals, Humans, Luciferase, Enhancer, Molecular Biology, Toxicologie, VLAG, DNA Primers, Pharmacology, Flavonoids, Electrophile-responsive element (EpRE), Taxifolin, Hereditary cancer and cancer-related syndromes [ONCOL 1], Base Sequence, subunit gene, Stable luciferase reporter cell lines, colorectal-cancer, Fisetin, Nonhuman, Molecular biology, chemistry, Human cell, detoxify carcinogens, Stereospecificity, Electrophile responsive element mediated gene, Controlled study
وصف الملف: application/octet-stream; application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a66c955569a7a1d9dac8a000f68c8feTest
http://resolver.tudelft.nl/uuid:a7d16055-5432-458e-8dc8-db7264681ea0Test -
8دورية أكاديمية
المؤلفون: Labanca, E., De Luca, P., Gueron, G., Paez, A., Moiola, C.P., Massillo, C., Porretti, J., Giudice, J., Zalazar, F., Navone, N., Vazquez, E., De Siervi, A.
مصطلحات موضوعية: BRCA1 protein, cyclin D1, doxorubicin, etoposide, gelatinase B, heme oxygenase 1, hydrogen peroxide, methotrexate, mitoxantrone, transcription factor Nrf2, human, HMOX1 protein, NFE2L2 protein, protein binding, animal cell, animal experiment, animal model, Article, cancer cell, controlled study, DNA damage, enzyme mechanism, homeostasis, human cell, immunofluorescence, in vitro study, in vivo study, male, mouse, nonhuman
-
9دورية أكاديمية
المؤلفون: Astort, F., Mercau, M., Giordanino, E., Degese, M.S., Caldareri, L., Coso, O., Cymeryng, C.B.
مصطلحات موضوعية: cGMP, Heme oxygenase 1, Nitric oxide, Nuclear factor-erythroid 2-related factor (Nrf2), Soluble guanylate cyclase, cyclic GMP, dactinomycin, diethylenetriamine, guanylate cyclase, guanylate cyclase inhibitor, messenger RNA, transcription factor Nrf2, antioxidant, Nfe2l2 protein, mouse, adrenal cortex cell, animal cell, article, cellular stress response, controlled study, enzyme induction, intracellular signaling, nonhuman, oxidative stress, priority journal, protein localization, regulatory mechanism, RNA degradation, transcription initiation, transient transfection
-
10دورية أكاديمية
المؤلفون: Astort, F., Repetto, E.M., Rocha-Viegas, L., Mercau, M.E., Sanchez Puch, S., Finkielstein, C.V., Pecci, A., Cymeryng, C.B.
مصطلحات موضوعية: Adrenocortical cells, CAMP/PKA, CREB, Heme oxygenase, PI3K, corticotropin, cyclic AMP, cyclic AMP responsive element binding protein, heme oxygenase 1, luciferase, n [2 (4 bromocinnamylamino)ethyl] 5 isoquinolinesulfonamide, phosphatidylinositol 3 kinase, protein kinase B, reactive oxygen metabolite, transcription factor Nrf2, protein binding, adrenal cortex cell, animal cell, Article, controlled study, enzyme activation, enzyme activity, enzyme induction, enzyme inhibition, gene overexpression, mouse, nonhuman, priority journal, promoter region, protein phosphorylation