المؤلفون: Gong-Her Wu, Charlene Smith-Geater, Jesús G. Galaz-Montoya, Yingli Gu, Sanket R. Gupte, Ranen Aviner, Patrick G. Mitchell, Joy Hsu, Ricardo Miramontes, Keona Q. Wang, Nicolette R. Geller, Cathy Hou, Cristina Danita, Lydia-Marie Joubert, Michael F. Schmid, Serena Yeung, Judith Frydman, William Mobley, Chengbiao Wu, Leslie M. Thompson, Wah Chiu

المصدر: Nature communications, vol 14, iss 1

مصطلحات موضوعية: Neurons, Proteomics, Huntington's Disease, Huntingtin Protein, Multidisciplinary, Animal, Induced Pluripotent Stem Cells, Neurosciences, General Physics and Astronomy, General Chemistry, Neurodegenerative, Stem Cell Research, General Biochemistry, Genetics and Molecular Biology, Mitochondria, Brain Disorders, Mice, Huntington Disease, Phenotype, Rare Diseases, Orphan Drug, Artificial Intelligence, Disease Models, Neurological, Animals, Humans

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4c64404d0da476045f534c77ca70608Test
https://escholarship.org/uc/item/8sk2g35qTest

المؤلفون: Ryan G. Lim, Osama Al-Dalahmah, Jie Wu, Maxwell P. Gold, Jack C. Reidling, Guomei Tang, Miriam Adam, David K. Dansu, Hye-Jin Park, Patrizia Casaccia, Ricardo Miramontes, Andrea M. Reyes-Ortiz, Alice Lau, Richard A. Hickman, Fatima Khan, Fahad Paryani, Alice Tang, Kenneth Ofori, Emily Miyoshi, Neethu Michael, Nicolette McClure, Xena E. Flowers, Jean Paul Vonsattel, Shawn Davidson, Vilas Menon, Vivek Swarup, Ernest Fraenkel, James E. Goldman, Leslie M. Thompson

المصدر: Nature communications, vol 13, iss 1

مصطلحات موضوعية: Huntington's Disease, General Physics and Astronomy, Biotin, Mice, Transgenic, Nerve Tissue Proteins, Neurodegenerative, General Biochemistry, Genetics and Molecular Biology, Transgenic, Mice, Rare Diseases, Genetics, Solitary Nucleus, 2.1 Biological and endogenous factors, Animals, Humans, Thiamine, Aetiology, Multidisciplinary, Animal, Neurosciences, General Chemistry, Stem Cell Research, Brain Disorders, Oligodendroglia, Disease Models, Animal, Huntington Disease, Disease Models, Neurological, Dietary Supplements, Stem Cell Research - Nonembryonic - Non-Human

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89f9948beef509831c9cf3152893e723Test
https://pubmed.ncbi.nlm.nih.gov/36543778Test

المؤلفون: Eva L. Morozko, Charlene Smith-Geater, Alejandro Mas Monteys, Subrata Pradhan, Ryan G. Lim, Peter Langfelder, Marketta Kachemov, Jayesh A. Kulkarni, Josh Zaifman, Austin Hill, Jennifer T. Stocksdale, Pieter R. Cullis, Jie Wu, Joseph Ochaba, Ricardo Miramontes, Anirban Chakraborty, Tapas K. Hazra, Alice Lau, Sophie St-cyr, Iliana Orellana, Lexi Kopan, Keona Q. Wang, Sylvia Yeung, Blair R. Leavitt, Jack C. Reidling, X. William Yang, Joan S. Steffan, Beverly L. Davidson, Partha S. Sarkar, Leslie M. Thompson

المصدر: Proc Natl Acad Sci U S A
Proceedings of the National Academy of Sciences of the United States of America, vol 118, iss 4

مصطلحات موضوعية: Huntington's Disease, 0301 basic medicine, Male, DNA Repair, Transcription, Genetic, Mutant, SUMO protein, Neurodegenerative, Inbred C57BL, Transgenic, Mice, 0302 clinical medicine, DNA damage repair, 2.1 Biological and endogenous factors, Aetiology, RNA, Small Interfering, Induced pluripotent stem cell, Neurons, Gene knockdown, Huntingtin Protein, Multidisciplinary, Cell Differentiation, Protein Inhibitors of Activated STAT, Ubiquitin ligase, Cell biology, Phosphotransferases (Alcohol Group Acceptor), Huntington Disease, Neurological, Small Ubiquitin-Related Modifier Proteins, Female, Transcription, Pluripotent Stem Cells, PIAS, DNA damage, 1.1 Normal biological development and functioning, Primary Cell Culture, Mice, Transgenic, Biology, Small Interfering, 03 medical and health sciences, Rare Diseases, Genetic, Huntington's disease, Underpinning research, Genetics, medicine, Animals, Humans, PNKP, Gene, Protein Processing, Animal, Post-Translational, Neurosciences, Sumoylation, Correction, DNA, Stem Cell Research, medicine.disease, Brain Disorders, Mice, Inbred C57BL, Disease Models, Animal, 030104 developmental biology, DNA Repair Enzymes, SUMO, Disease Models, biology.protein, RNA, Protein Processing, Post-Translational, 030217 neurology & neurosurgery, DNA Damage

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e38249a9a6accb8170577dc07adbd259Test
https://pubmed.ncbi.nlm.nih.gov/34341126Test