Functional Neuroimaging of Breastfeeding Analgesia by Multichannel Near-Infrared Spectroscopy
| العنوان: | Functional Neuroimaging of Breastfeeding Analgesia by Multichannel Near-Infrared Spectroscopy |
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| المؤلفون: | Andrea Clarici, Stefano Massaccesi, Sergio Demarini, Stefano Bembich, Pierpaolo Brovedani, Riccardo Davanzo |
| المساهمون: | Bembich, Stefano, Riccardo, Davanzo, Brovedani, Pierpaolo, Clarici, Andrea, Massaccesi, Stefano, Demarini, Sergio |
| المصدر: | Neonatology. 104:255-259 |
| بيانات النشر: | S. Karger AG, 2013. |
| سنة النشر: | 2013 |
| مصطلحات موضوعية: | Male, newborns, Analgesic, Neonatal pain, Breastfeeding, Administration, Oral, Pain, Pilot Projects, Somatosensory system, Multisensory stimulation, Functional neuroimaging, Humans, Medicine, Pain perception, Pain expression, Pain Measurement, Spectroscopy, Near-Infrared, business.industry, Functional Neuroimaging, Infant, Newborn, cortical activation, Pain Perception, Somatosensory Cortex, Breast Feeding, Glucose, Treatment Outcome, Anesthesia, Pediatrics, Perinatology and Child Health, Female, Analgesia, business, Developmental Biology |
| الوصف: | Background: Newborns perceive pain, and several non-pharmacologic analgesic methods have been used during painful procedures. Activation of the neonatal somatosensory cortex, in association with a painful procedure without analgesia, has been demonstrated by two-channel near-infrared spectroscopy (NIRS). Objectives: To evaluate both cortical and behavioural responses of healthy term newborns to a painful procedure during two non-pharmacologic analgesic interventions, i.e. glucose solution and breastfeeding. Methods: The effects of glucose and breastfeeding on pain-associated neonatal cortical activity were studied in two groups (n = 30) by multichannel NIRS during a heel prick. Cortical activation was identified by variations in oxygenated haemoglobin. Neonatal pain expression was assessed by a validated scale. Results: No significant variations in cortical activity emerged using glucose solution, whereas breastfed newborns showed widespread cortical activation. Breastfed neonates showed significantly less behavioural pain expression. Conclusions: Glucose is associated with no significant cortical activation and may interfere with pain-associated response at the cortical level. Conversely, breastfeeding analgesia is associated with generalized cortical activation and may act by multisensory stimulation, possibly overwhelming pain perception. |
| وصف الملف: | ELETTRONICO |
| تدمد: | 1661-7819 1661-7800 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1aa2108001c5a473153eaae4eeee297fTest https://doi.org/10.1159/000353386Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....1aa2108001c5a473153eaae4eeee297f |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 16617819 16617800 |
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