المؤلفون: Andrea Cavalli, Anna Minarini, Antonino Cattaneo, Michela Rosini, Andrea Tarozzi, Vincenza Andrisano, Maria Laura Bolognesi, Patrizia Hrelia, Giorgio Lenaz, Rita Banzi, Manuela Bartolini, Christian Bergamini, Carlo Melchiorre, Romana Fato, Vincenzo Tumiatti, Maurizio Recanatini

المساهمون: Bolognesi ML, Banzi R, Bartolini M, Cavalli A, Tarozzi A, Andrisano V, Minarini A, Rosini M, Tumiatti V, Bergamini C, Fato R, Lenaz G, Hrelia P, Cattaneo A, Recanatini M, Melchiorre C., Bolognesi, Ml, Banzi, R, Bartolini, M, Cavalli, A, Tarozzi, A, Andrisano, V, Minarini, A, Rosini, M, Tumiatti, V, Bergamini, C, Fato, R, Lenaz, G, Hrelia, P, Cattaneo, Antonino, Recanatini, M, Melchiorre, C.

المصدر: Journal of medicinal chemistry. 50(20)

مصطلحات موضوعية: Models, Molecular, Amyloid beta, Plasma protein binding, medicine.disease_cause, Ligands, Antioxidants, MULTITARGET, Cell Line, Substrate Specificity, chemistry.chemical_compound, Structure-Activity Relationship, Alzheimer Disease, Drug Discovery, medicine, NAD(P)H Dehydrogenase (Quinone), Polyamines, Structure–activity relationship, Humans, Binding site, Butyrylcholinesterase, Amyloid beta-Peptides, Binding Sites, biology, Chemistry, Quinones, medicine.disease, AMYLOID-BETA, Acetylcholinesterase, Oxidative Stress, Biochemistry, ALZHEIMER'S DISEASE, biology.protein, Molecular Medicine, Cholinesterase Inhibitors, Alzheimer's disease, Reactive Oxygen Species, Oxidative stress, Protein Binding

وصف الملف: STAMPA

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1ae0f0f5155ca76a5f3596bd588cb39Test
https://pubmed.ncbi.nlm.nih.gov/17850125Test

المؤلفون: Carlo Melchiorre, Andrea Milelli, Vincenzo Tumiatti, Michela Rosini, Anna Minarini, Maria Laura Bolognesi

المساهمون: Tumiatti V., Minarini A., Bolognesi M.L., Milelli A., Rosini M., Melchiorre C.

المصدر: Current Medicinal Chemistry. 17:1825-1838

مصطلحات موضوعية: Models, Molecular, Disease, Pharmacology, Biochemistry, Structure-Activity Relationship, chemistry.chemical_compound, Alzheimer Disease, Biological profile, Drug Discovery, medicine, Humans, TACRINE HETERODIMERS, Amyloid beta-Peptides, DUAL BINDING ACETYLCHOLINESTERASE INHIBITORS, business.industry, Organic Chemistry, medicine.disease, Acetylcholinesterase, chemistry, Tacrine, MULTI-TARGET-DIRECTED LIGANDS (MTDLS), Molecular Medicine, Cholinesterase Inhibitors, Alzheimer's disease, NEURODEGENERATIVE DISEASES, business, medicine.drug

وصف الملف: STAMPA

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59c756a4aaec2c3b4201e195902f410aTest
https://doi.org/10.2174/092986710791111206Test

المؤلفون: Maria Laura Bolognesi, Vincenza Andrisano, and Andrea Tarozzi, Anna Minarini, Manuela Bartolini, Patrizia Hrelia, Michela Rosini, Carlo Melchiorre

المساهمون: ROSINI M., ANDRISANO V., BARTOLINI M., BOLOGNESI M. L., HRELIA P., MINARINI A., TAROZZI A., MELCHIORRE C.

المصدر: Journal of Medicinal Chemistry. 48:360-363

مصطلحات موضوعية: Pharmacology, Antioxidants, Cell Line, Structure-Activity Relationship, chemistry.chemical_compound, Alzheimer Disease, Biological property, Drug Discovery, medicine, Humans, Structure–activity relationship, Nootropic Agents, Neurons, chemistry.chemical_classification, Reactive oxygen species, Amyloid beta-Peptides, Anti alzheimer, Thioctic Acid, Lipoic acid, chemistry, Butyrylcholinesterase, Tacrine, Acetylcholinesterase, Molecular Medicine, Cholinesterase Inhibitors, Pharmacophore, Reactive Oxygen Species, Lead compound, medicine.drug

وصف الملف: STAMPA

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8aee38e5f1df968b2a0f1d0c510da24Test
https://doi.org/10.1021/jm049112hTest

المؤلفون: Carlo Melchiorre, Maria Laura Bolognesi, Anna Minarini, Michela Rosini, Elena Simoni, Vincenzo Tumiatti

المساهمون: Bolognesi M.L., Simoni E., Rosini M., Minarini A., Tumiatti V., Melchiorre C

مصطلحات موضوعية: Drug, media_common.quotation_subject, Computational biology, Disease, Pharmacology, Ligands, Alzheimer Disease, Alkanes, medicine, Ethylamines, Animals, Humans, Enzyme Inhibitors, media_common, Amyloid beta-Peptides, Thioctic Acid, Drug discovery, business.industry, General Medicine, DRUG DISCOVERY, Tacrine, Molecular targets, Acetylcholinesterase, business, NEURODEGENERATIVE DISEASES, medicine.drug

وصف الملف: STAMPA

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd763a546e1db61961b2fdbedbe66576Test
http://hdl.handle.net/11585/108616Test

المؤلفون: Gianpaolo Chiriano, Maria Laura Bolognesi, Giovanni Bottegoni, Manfred Windisch, Vincenzo Tumiatti, Michela Rosini, Carlo Melchiorre, Manuela Bartolini, Andrea Cavalli, Vincenza Andrisano, Valentina Maestri, Anna Minarini, Stefan Czvitkovich, Francesca Mancini

المساهمون: Bolognesi ML, Chiriano G, Bartolini M, Mancini F, Bottegoni G, Maestri V, Czvitkovich S, Windisch M, Cavalli A, Minarini A, Rosini M, Tumiatti V, Andrisano V, Melchiorre C.

مصطلحات موضوعية: Models, Molecular, Aché, Stereochemistry, Cell Survival, Molecular Conformation, In Vitro Techniques, Ligands, Bivalent (genetics), chemistry.chemical_compound, Structure-Activity Relationship, Catalytic Domain, Drug Discovery, Alkanes, Ethylamines, Animals, Humans, Neurons, Amyloid beta-Peptides, ALZHEIMER’S DISEASE, Affinities, language.human_language, In vitro, Peptide Fragments, APP metabolism, Monomer, chemistry, Butyrylcholinesterase, Amyloid aggregation, language, Acetylcholinesterase, Molecular Medicine, Cholinesterase Inhibitors, Amyloid Precursor Protein Secretases, Chickens, Protein Binding

وصف الملف: STAMPA

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6915ab35436d2c99c205c324dfb6ba17Test
http://hdl.handle.net/11585/109307Test

المؤلفون: Michela Rosini, Federica Lizzi, Maria Laura Bolognesi, Andrea Milelli, Carlo Melchiorre, Manuela Bartolini, Vincenza Andrisano, Anna Minarini, Patrizia Hrelia, Andrea Tarozzi, Fabiana Morroni

المساهمون: Bolognesi M.L., Bartolini M., Tarozzi A., Morroni F., Lizzi F., Milelli A., Minarini A., Rosini M., Hrelia P., Andrisano V., Melchiorre C.

المصدر: Bioorganicmedicinal chemistry letters. 21(9)

مصطلحات موضوعية: Amyloid, Clinical Biochemistry, Pharmaceutical Science, Biochemistry, chemistry.chemical_compound, Inhibitory Concentration 50, Drug Delivery Systems, Alzheimer Disease, Alkanes, Drug Discovery, Ethylamines, Humans, Benzofuran, Enzyme Inhibitors, Molecular Biology, Cells, Cultured, Amyloid beta-Peptides, biology, Molecular Structure, Drug discovery, Organic Chemistry, Acetylcholinesterase, Benzothiazole, chemistry, Enzyme inhibitor, biology.protein, Curcumin, Molecular Medicine, Cholinesterase Inhibitors, NEURODEGENERATIVE DISEASES, Lead compound

وصف الملف: STAMPA

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7aa91f4f7ca1dbc2cea971772e8437b5Test
https://pubmed.ncbi.nlm.nih.gov/21236667Test

المؤلفون: Carlo Melchiorre, Michela Rosini, Maria Laura Bolognesi, Manuela Bartolini, Vincenza Andrisano

المساهمون: Bolognesi ML, Bartolini M, Rosini M, Andrisano V, Melchiorre C.

المصدر: Bioorganicmedicinal chemistry letters. 19(15)

مصطلحات موضوعية: Stereochemistry, Clinical Biochemistry, Substituent, Pharmaceutical Science, Biochemistry, Chemical synthesis, chemistry.chemical_compound, Inhibitory Concentration 50, Mice, Structure-Activity Relationship, Alzheimer Disease, Drug Discovery, Alkanes, medicine, Ethylamines, Polyamines, Animals, Humans, Amines, Molecular Biology, Amyloid beta-Peptides, Dose-Response Relationship, Drug, Hydrolysis, Organic Chemistry, Diastereomer, Quinones, Stereoisomerism, Acetylcholinesterase, Small molecule, Mechanism of action, chemistry, Models, Chemical, Molecular Medicine, medicine.symptom, Enantiomer, Chirality (chemistry)

وصف الملف: STAMPA

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4b025f3491fb5e46f3a95538cd7d07bTest
https://pubmed.ncbi.nlm.nih.gov/19505825Test

المؤلفون: Vincenza Andrisano, Michela Rosini, Maria Laura Bolognesi, Manuela Bartolini, Carlo Melchiorre, Romana Fato, Giorgio Lenaz, Andrea Cavalli, Christian Bergamini

المساهمون: Bolognesi ML, Cavalli A, Bergamini C, Fato R, Lenaz G, Rosini M, Bartolini M, Andrisano V, Melchiorre C.

مصطلحات موضوعية: Antioxidant, medicine.drug_class, Ubiquinone, medicine.medical_treatment, Submitochondrial Particles, Carboxamide, Ligands, Antioxidants, Electron Transport, chemistry.chemical_compound, Alzheimer Disease, Cell Line, Tumor, Drug Discovery, Alkanes, medicine, Ethylamines, Humans, Amyloid beta-Peptides, biology, Thioctic Acid, Rational design, Acetylcholinesterase, Benzoquinone, Lipoic acid, chemistry, Biochemistry, Enzyme inhibitor, Drug Design, biology.protein, Molecular Medicine, Reactive Oxygen Species, Function (biology), Protein Binding

وصف الملف: STAMPA

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::059ee8f15e58e064ed3cec87811cd724Test
http://hdl.handle.net/11585/84134Test

المؤلفون: Andrea Cavalli, Maria Laura Bolognesi, Carlo Melchiorre

المساهمون: Bolognesi ML, Cavalli A, Melchiorre C.

مصطلحات موضوعية: Drug, Tau hyperphosphorylation, media_common.quotation_subject, Plaque, Amyloid, tau Proteins, Review Article, Disease, Anisoles, Biology, Antioxidants, Choline, Multi target, Alzheimer Disease, Memory, Biological profile, Alkanes, Ethylamines, Animals, Aspartic Acid Endopeptidases, Humans, Attention, Pharmacology (medical), Phosphorylation, Available drugs, media_common, Neurons, Pharmacology, Amyloid beta-Peptides, Galantamine, Drug discovery, Ligand (biochemistry), Amides, Drug Design, Neurology (clinical), Amyloid Precursor Protein Secretases, Neuroscience, Platelet Aggregation Inhibitors

وصف الملف: STAMPA

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9fd1839ab4a8471ffc63cacdc055bc83Test
http://hdl.handle.net/11585/84142Test

المؤلفون: Maria Laura Bolognesi, Manuela Bartolini, Carlo Melchiorre, Vincenza Andrisano, Andrea Cavalli, Maurizio Recanatini, Michela Rosini, Luca Valgimigli

المساهمون: Bolognesi ML, Cavalli A, Valgimigli L, Bartolini M, Rosini M, Andrisano V, Recanatini M, Melchiorre C

مصطلحات موضوعية: Models, Molecular, medicine.drug_class, Ligands, Ferric Compounds, Structure-Activity Relationship, chemistry.chemical_compound, Alzheimer Disease, Drug Discovery, medicine, Humans, Structure–activity relationship, Binding site, Chelating Agents, Amyloid beta-Peptides, Binding Sites, biology, Biological activity, Acetylcholinesterase, Peptide Fragments, chemistry, Acetylcholinesterase inhibitor, Biochemistry, Enzyme inhibitor, Butyrylcholinesterase, Drug Design, Tacrine, biology.protein, Thermodynamics, Molecular Medicine, Cholinesterase Inhibitors, Lead compound, Copper, medicine.drug

وصف الملف: STAMPA

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e7b237e16654741393b4fff129e7597Test
http://hdl.handle.net/11585/52760Test