Clinical features of patients with -lactamase producing Haemophilus influenzae isolated from sputum
| العنوان: | Clinical features of patients with -lactamase producing Haemophilus influenzae isolated from sputum |
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| المؤلفون: | Hilary Humphreys, S. R. Johnson, R. C. F. Thompson, J. T. Macfarlane |
| المصدر: | Journal of Antimicrobial Chemotherapy. 38:881-884 |
| بيانات النشر: | Oxford University Press (OUP), 1996. |
| سنة النشر: | 1996 |
| مصطلحات موضوعية: | Adult, Lung Diseases, Male, Microbiology (medical), Haemophilus Infections, medicine.disease_cause, beta-Lactamases, Microbiology, Haemophilus influenzae, Amp resistance, Ampicillin, Lower respiratory tract infection, medicine, Humans, Pharmacology (medical), Beta (finance), Respiratory Tract Infections, Aged, Retrospective Studies, Antibacterial agent, Aged, 80 and over, Pharmacology, business.industry, Smoking, Sputum, Middle Aged, Amoxicillin, medicine.disease, Anti-Bacterial Agents, Infectious Diseases, Chronic Disease, Female, medicine.symptom, business, Ampicillin Resistance, medicine.drug |
| الوصف: | Ampicillin resistance amongst isolates of Haemophilus influenzae is of increasing concern but its clinical impact is unclear. We performed a retrospective study of 34 hospital patients with lower respiratory tract infection (LRTI) caused by beta-lactamase positive (beta+) H. influenzae and compared these with 34 control patients with LRTI caused by beta-lactamase negative (beta-) strains. Chronic obstructive pulmonary disease was the most common underlying condition in both groups (beta+ 23/24, beta- 25/34). A recent course of antibiotics, especially ampicillin/amoxycillin, was significantly (P < 0.05) more common in the beta+ group (beta+ 17/34, beta- 3/34). Other pathogens were isolated more frequently in the beta+ group (beta+ 10/34, beta- 4/34). There was no difference in outcome between the two groups. |
| تدمد: | 1460-2091 0305-7453 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d35f32fd513b067319dad62b70af374fTest https://doi.org/10.1093/jac/38.5.881Test |
| رقم الانضمام: | edsair.doi.dedup.....d35f32fd513b067319dad62b70af374f |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 14602091 03057453 |
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