دورية أكاديمية

Efficacy of intravenous ciprofloxacin in patients with febrile neutropenia refractory to initial therapy.

التفاصيل البيبلوغرافية
العنوان: Efficacy of intravenous ciprofloxacin in patients with febrile neutropenia refractory to initial therapy.
المؤلفون: Matsuoka, Hitoshi, Tsukamoto, Atsuko, Shirahashi, Akihiko, Koga, Shin, Suzushima, Hitoshi, Shibata, Keisuke, Uozumi, Kimiharu, Yamashita, Kiyoshi, Okamura, Seiichi, Kawano, Fumio, Tamura, Kazuo
المصدر: Leukemia & Lymphoma; Aug2006, Vol. 47 Issue 8, p1618-1623, 6p, 1 Diagram, 3 Charts
مصطلحات موضوعية: FEBRILE neutropenia, COMMUNICABLE diseases, CIPROFLOXACIN, AMINOGLYCOSIDES, INTRAVENOUS injections, THERAPEUTICS
مستخلص: We previously reported that monotherapy with carbapenem or cefepime exhibited efficacy equivalent to cefepime plus an aminoglycoside as initial therapy for febrile neutropenia (FN), achieving an adequate response in two-thirds of the patients. However, only one-third of the remaining poor responders to monotherapy became afebrile after an aminoglycoside was added to the initial carbapenem or cefepime. The present study was designed to evaluate the benefit of intravenous ciprofloxacin for neutropenic patients with fever who were refractory to initial therapy given for the first 3 days. Patients with FN—as defined by an axillary temperature ≥37.5°C and a neutrophil count [ABSTRACT FROM AUTHOR]
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قاعدة البيانات: Complementary Index
الوصف
تدمد:10428194
DOI:10.1080/10428190600572731