رسالة جامعية
Efeito da complementação do dipeptídeo alanilglutamina parenteral precoce nos marcadores inflamatórios e nos índices prognósticos em pacientes críticos após cirurgia de grande porte abdominal
| العنوان: | Efeito da complementação do dipeptídeo alanilglutamina parenteral precoce nos marcadores inflamatórios e nos índices prognósticos em pacientes críticos após cirurgia de grande porte abdominal |
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| المؤلفون: | Silva, Eliseuda Marinho da |
| المساهمون: | Costa, Maria José de Carvalho, http://lattes.cnpq.br/1587362514258201Test |
| بيانات النشر: | Universidade Federal da Paraíba Brasil Ciências da Nutrição Programa de Pós-Graduação em Ciências da Nutrição UFPB |
| سنة النشر: | 2021 |
| المجموعة: | Universidade Federal da Paraiba: Biblioteca Digital de Teses e Dissertações |
| مصطلحات موضوعية: | Nutrição parenteral total, Aminoácidos, Cirurgia, Inflamação, Resultados de cuidados crítico, Evolução clínica, Total parenteral nutrition, Amino acids, Surgery, Inflammation, Critical care results, Clinical evolution, CNPQ::CIENCIAS DA SAUDE::NUTRICAO |
| الوصف: | Low concentrations of glutamine are present in the plasma of patients admitted to the ICU (Intensive Care Unit), with emphasis on major abdominal surgeries, which are associated with increased complications and mortality. Thus, this thesis was intended to evaluate the effect of complementation of the early parenteral alanylglutamine dipeptide on inflammatory markers and prognostic indexes in critically ill patients after major abdominal surgery. It is a randomized controlled double-blind clinical trial consisted of two groups, one named intervention and another named control, made up by individuals who underwent major abdominal surgery and with the use of parenteral nutrition in the Intensive Care Unit of the Hospital University student Lauro Wanderley. Demographic and anthropometric data, prognostic indexes, diagnoses, hematological and biochemical tests, time of intervention, reasons for discontinuing the intervention, length of stay in ICU and hospital, as well as mortality rates, were collected. The sample was composed of 12 patients, 6 patients in each group on a 1: 1 basis in 30 months. Highlighting statistical significance, in the intervention group, it was observed that total serum proteins in the group before the intervention had an average of 4.50 ± 0.87 and after, it was 5.17 ± 0.82 with p = 0.046, serum albumin before the intervention presented an average of 1.97 ± 0.39 and after, it was 2.35 ± 0.63 with p = 0.026, serum CRP (C Reactive Protein) before the intervention presented with an average of 199.36 ± 91.73 and after, it was 132.53 ± 103.81 with p = 0.028 and the CRP/albumin ratio before the intervention presented an avarege of 105.79 ± 49.75 and after, it was 59.76 ± 49.44 with p = 0.028. When considering the intervention group without the two patients who were surgically re-approached, after the intervention, it was observed between the two groups that there was a reduction in blood glucose in the intervention group, with an average of 136.67 ± 58.78 versus 144.00 ± 40.97 in the control group ... |
| نوع الوثيقة: | thesis |
| اللغة: | Portuguese |
| العلاقة: | https://repositorio.ufpb.br/jspui/handle/123456789/20248Test |
| الإتاحة: | https://repositorio.ufpb.br/jspui/handle/123456789/20248Test |
| حقوق: | Acesso aberto ; http://creativecommons.org/licenses/by-nd/3.0/brTest/ |
| رقم الانضمام: | edsbas.A643F714 |
| قاعدة البيانات: | BASE |
| الوصف غير متاح. |