نتائج البحث - "Wyatt W, Yue"

1

Defining substrate selection by rhinoviral 2A proteinase through its crystal structure with the inhibitor zVAM.fmk

المؤلفون: Gustavo Arruda Bezerra, Tim Skern, Wyatt W. Yue, Karin M. Deutschmann-Olek

المصدر: Virology. 562:128-141

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::383529bffe662fb2773cde3ad54d9453Test
https://doi.org/10.1016/j.virol.2021.07.008Test

2

Bi-allelic Variants in TKFC Encoding Triokinase/FMN Cyclase Are Associated with Cataracts and Multisystem Disease

المؤلفون: Fatma Taha, Daniel Weghuber, Johannes A. Mayr, Johannes Spenger, Elaina M. Maldonado, Florence van den Broek, Wyatt W. Yue, Saskia B. Wortmann, Simon Heales, Zdenek Jaros, Brigitte Meunier, Lamia Mestek-Boukhibar, Shamima Rahman, James Davison, Emma Clement

المساهمون: Institut de Biologie Intégrative de la Cellule (I2BC), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS), Biogenèse et fonctionnement des complexes OXPHOS mitochondriaux (BIOMIT), Département Biologie Cellulaire (BioCell), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS)-Institut de Biologie Intégrative de la Cellule (I2BC), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS)

المصدر: American Journal of Human Genetics
American Journal of Human Genetics, 2020, 106, pp.256-263. ⟨10.1016/j.ajhg.2020.01.005⟩
American Journal of Human Genetics, Elsevier (Cell Press), 2020, 106, pp.256-263. ⟨10.1016/j.ajhg.2020.01.005⟩
Am. J. Hum. Genet. 106, 256-263 (2020)
Am J Hum Genet

مصطلحات موضوعية: Male, 0301 basic medicine, Developmental Disabilities, Microcytic anemia, [SDV]Life Sciences [q-bio], rapid genome sequencing, Sequence Homology, 0302 clinical medicine, Cerebellum, cyclic FMN, Phosphorylation, innate immunity, Genetics (clinical), Exome sequencing, 2. Zero hunger, Genetics, Homozygote, Galactosemia, Pedigree, 3. Good health, developmental delay, Phosphotransferases (Alcohol Group Acceptor), Phenotype, Child, Preschool, Lactic acidosis, cataracts, Female, Phosphorus-Oxygen Lyases, TKFC, Biology, Nervous System Malformations, Cyclase, Cataract, 03 medical and health sciences, Report, Exome Sequencing, medicine, inborn error of metabolism, Humans, Phosphofructokinase 2, Amino Acid Sequence, Kinase activity, Alleles, Cardiomyopathy, Cataracts, Cyclic Fmn, Developmental Delay, Fructose Metabolism, Inborn Error Of Metabolism, Innate Immunity, Rapid Genome Sequencing, Tkfc, Triokinase, Infant, medicine.disease, triokinase, fructose metabolism, 030104 developmental biology, Inborn error of metabolism, Mutation, cardiomyopathy, 030217 neurology & neurosurgery

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a704de9174a9612ac3e1dd7437d847fTest
https://hal.science/hal-02464288/documentTest

3

Structural basis for the regulation of human 5,10-methylenetetrahydrofolate reductase by phosphorylation and S-adenosylmethionine inhibition

المؤلفون: Elzbieta Rembeza, D. Sean Froese, Terttu Suormala, Anselm Erich Oberholzer, Oktawia Borkowska, Wyatt W. Yue, Jolanta Kopec, Gustavo Arruda Bezerra, Rod Chalk, Seraina Lutz, Matthias R. Baumgartner

المساهمون: University of Zurich, Froese, D Sean

المصدر: Nature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
Nature Communications

مصطلحات موضوعية: 0301 basic medicine, Models, Molecular, Protein Folding, S-Adenosylmethionine, General Physics and Astronomy, Reductase, Crystallography, X-Ray, Mass Spectrometry, chemistry.chemical_compound, 0302 clinical medicine, Protein structure, X-Ray Diffraction, Catalytic Domain, Phosphorylation, lcsh:Science, Multidisciplinary, biology, Chemistry, 3100 General Physics and Astronomy, Recombinant Proteins, Biochemistry, Science, Protein domain, Allosteric regulation, 610 Medicine & health, 1600 General Chemistry, Molecular Dynamics Simulation, General Biochemistry, Genetics and Molecular Biology, Article, Evolution, Molecular, 03 medical and health sciences, Biosynthesis, Protein Domains, 1300 General Biochemistry, Genetics and Molecular Biology, Scattering, Small Angle, Humans, Amino Acid Sequence, Protein Structure, Quaternary, Methylenetetrahydrofolate Reductase (NADPH2), Methionine, General Chemistry, digestive system diseases, Kinetics, 030104 developmental biology, 10036 Medical Clinic, Methylenetetrahydrofolate reductase, biology.protein, lcsh:Q, 030217 neurology & neurosurgery, NADP

وصف الملف: 41467_2018_Article_4735.pdf - application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25c668c6b07c00337b17f534542d0bceTest
http://link.springer.com/article/10.1038/s41467-018-04735-2Test

4

Crystal structure of Porphyromonas gingivalis peptidylarginine deiminase: implications for autoimmunity in rheumatoid arthritis

المؤلفون: Marie-Laëtitia Thézénas, N.A. Burgess-Brown, Roman Fischer, Patrick J Venables, Leela Shrestha, Anna B Montgomery, Wyatt W. Yue, Jolanta Kopec

المصدر: Annals of the Rheumatic Diseases

مصطلحات موضوعية: 0301 basic medicine, Models, Molecular, Hydrolases, Immunology, Molecular Sequence Data, Arthritis, Autoimmunity, Rheumatoid Arthritis, Fibrinogen, medicine.disease_cause, Crystallography, X-Ray, General Biochemistry, Genetics and Molecular Biology, Catalysis, Substrate Specificity, Arthritis, Rheumatoid, 03 medical and health sciences, Structure-Activity Relationship, Rheumatology, Immunology and Allergy, Medicine, Humans, Amino Acid Sequence, Peptide sequence, Porphyromonas gingivalis, Basic and Translational Research, biology, business.industry, Citrullination, medicine.disease, biology.organism_classification, PPAD, Gingipain, 030104 developmental biology, Biochemistry, Ant-CCP, Mutagenesis, Site-Directed, Protein-Arginine Deiminases, Citrulline, business, Crystallization, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91009714b4b08847a71601c014b2f8fcTest
https://ora.ox.ac.uk/objects/uuid:6944c2a9-e1c6-4a1f-82b8-ea85eb3b80eeTest

5

15-deoxy-Δ

المؤلفون: Giancarlo, Abis, Rebecca L, Charles, Jolanta, Kopec, Wyatt W, Yue, R Andrew, Atkinson, Tam T T, Bui, Steven, Lynham, Simona, Popova, Yin-Biao, Sun, Franca, Fraternali, Philip, Eaton, Maria R, Conte

المصدر: Communications Biology

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=pmid________::eead94446ff59076082513a0dd002c52Test
https://pubmed.ncbi.nlm.nih.gov/31123712Test

6

RAC1 Missense Mutations in Developmental Disorders with Diverse Phenotypes

المساهمون: Klinische Genetica, RS: GROW - R4 - Reproductive and Perinatal Medicine, MUMC+: DA Klinische Genetica (5), Clinical Genetics

المصدر: American Journal of Human Genetics, 101(3), 466-477. Cell Press
American Journal of Human Genetics, 101, 466-477
Reijners, M, Mohamad Ansor, N, Kousi, M, Yue, W, Tan, P, Clarkson, K, Clayton-Smith, J, Corning, K, Jones, J, Lam, W, Mancini, G, Marcelis, C, Mohammed, S, Pfundt, R, Roifman, M, Cohn, R, Chiayat, D, Millard, T, Katsanis, N, Brunner, H & Banka, S 2017, ' RAC1 Missense Mutations in Developmental Disorders with Diverse Phenotypes ', American Journal of Human Genetics, vol. 101, no. 3, pp. 466-477 . https://doi.org/10.1016/j.ajhg.2017.08.007Test
American Journal of Human Genetics, 101, 3, pp. 466-477

مصطلحات موضوعية: Male, rac1 GTP-Binding Protein, 0301 basic medicine, Microcephaly, Embryo, Nonmammalian, INTELLECTUAL DISABILITY, Developmental Disabilities, VARIANTS, Mice, 0302 clinical medicine, Missense mutation, Child, Zebrafish, Genetics (clinical), Genetics, Brain Diseases, biology, RHO GTPASES, CDC42, Phenotype, Pedigree, FAMILY, Child, Preschool, SURVIVAL, GROWTH, Female, Rare cancers Radboud Institute for Health Sciences [Radboudumc 9], EXPRESSION, Adolescent, In silico, Mutation, Missense, Context (language use), 03 medical and health sciences, Report, medicine, Animals, Humans, Amino Acid Sequence, Allele, Gene, SPECTRUM, Neurodevelopmental disorders Donders Center for Medical Neuroscience [Radboudumc 7], Infant, biology.organism_classification, medicine.disease, 030104 developmental biology, 030217 neurology & neurosurgery, SYSTEM