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المؤلفون: De Mao Chen, Nigel H. Greig, Kumar Sambamurti, Harold W. Holloway, Tada Utsuki, Qian Sheng Yu, Debomoy K. Lahiri, Bryan Maloney, Tony Giordano
المصدر: Journal of Pharmacology and Experimental Therapeutics. 320:386-396
مصطلحات موضوعية: Male, Amyloid, medicine.drug_class, Physostigmine, Alpha (ethology), Pharmacology, Amyloid beta-Protein Precursor, Mice, Alzheimer Disease, In vivo, Cell Line, Tumor, mental disorders, medicine, Animals, Humans, RNA, Messenger, Senile plaques, Cerebral Cortex, Amyloid beta-Peptides, Dose-Response Relationship, Drug, Chemistry, Stereoisomerism, Mice, Inbred C57BL, Dose–response relationship, Acetylcholinesterase inhibitor, Biochemistry, Cell culture, Molecular Medicine, Cholinergic, Cholinesterase Inhibitors, Amyloid Precursor Protein Secretases
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6439ed5b30d25eb61d50559b7b7ec3dcTest
https://doi.org/10.1124/jpet.106.112102Test -
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المؤلفون: Nigel H. Greig, Mark S. Kindy, Kumar Sambamurti, Jacobo Mintzer, Narayan R. Bhat, Ann-Charlotte Granholm, Debomoy K. Lahiri
المصدر: Current Drug Targets. 5:517-528
مصطلحات موضوعية: Apolipoprotein E, Amyloid, Clinical Biochemistry, Presenilin, Alzheimer Disease, Risk Factors, mental disorders, Drug Discovery, medicine, Animals, Humans, Senile plaques, Cells, Cultured, Pharmacology, Clinical Trials as Topic, biology, Neurodegeneration, Environmental Exposure, Environmental exposure, medicine.disease, Diet, Disease Models, Animal, Cholesterol, Biochemistry, Immunology, biology.protein, Molecular Medicine, Alzheimer's disease, Amyloid precursor protein secretase
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7474e38e6136e46f9e388238131e41bTest
https://doi.org/10.2174/1389450043345335Test -
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المؤلفون: Girish J. Kotwal, Anders A. F. Sima, Debomoy K. Lahiri, Kumar Sambamurti, Martin R. Farlow, W. Kupsky, F. H. Sarkar
المصدر: Annals of the New York Academy of Sciences. 973:334-339
مصطلحات موضوعية: Amyloid, Immunoprecipitation, Molecular Sequence Data, CHO Cells, General Biochemistry, Genetics and Molecular Biology, Amyloid beta-Protein Precursor, History and Philosophy of Science, Western blot, Alzheimer Disease, Antibody Specificity, Cricetinae, mental disorders, medicine, Amyloid precursor protein, Animals, Humans, Amino Acid Sequence, Senile plaques, medicine.diagnostic_test, biology, Chemistry, General Neuroscience, P3 peptide, Brain, Immunohistochemistry, Peptide Fragments, Biochemistry of Alzheimer's disease, Cell biology, Biochemistry, biology.protein, Autopsy, Amyloid precursor protein secretase
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1dce2403460616ec2b8bdfedc84e7355Test
https://doi.org/10.1111/j.1749-6632.2002.tb04661.xTest -
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المؤلفون: Nigel H. Greig, Debomoy K. Lahiri, Kumar Sambamurti
المصدر: NeuroMolecular Medicine. 1:1-32
مصطلحات موضوعية: Apolipoprotein E, Amyloid beta-Peptides, Amyloid, biology, Neurodegeneration, P3 peptide, medicine.disease, Presenilin, Amyloid beta-Protein Precursor, Cellular and Molecular Neuroscience, Neurology, Biochemistry, Alzheimer Disease, mental disorders, biology.protein, medicine, Amyloid precursor protein, Humans, Molecular Medicine, Senile plaques, Biology, Molecular Biology, Amyloid precursor protein secretase, Aged
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8deaf78c1e83c77234ab1ac1d71906f7Test
https://doi.org/10.1385/nmm:1:1:1Test -
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المؤلفون: Christian Mihail Prada, John Hardy, Kumar Sambamurti, Nitin D. Mehta, Chris Eckman, Steven G. Younkin, Debora Yager, Lawrence M. Refolo
المصدر: Journal of Neurochemistry. 73:2383-2388
مصطلحات موضوعية: Amyloid, animal diseases, Mutant, Biology, Kidney, Transfection, medicine.disease_cause, Biochemistry, Presenilin, Cell Line, Cellular and Molecular Neuroscience, Alzheimer Disease, Tubulin, mental disorders, Presenilin-1, medicine, Amyloid precursor protein, Humans, RNA, Antisense, Mutation, Amyloid beta-Peptides, Membrane Proteins, Molecular biology, Peptide Fragments, nervous system diseases, Antisense RNA, Gene Expression Regulation, nervous system, Cell culture, Doxycycline, Immunology, biology.protein
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46eaef380c2cd1d59f1c4b4eef90870bTest
https://doi.org/10.1046/j.1471-4159.1999.0732383.xTest -
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المؤلفون: Lorenzo M. Refolo, Kumar Sambamurti, Swetal Gandhi
المصدر: Journal of molecular neuroscience : MN. 24(1)
مصطلحات موضوعية: ADAM17 Protein, Hydroxamic Acids, Presenilin, Cellular and Molecular Neuroscience, chemistry.chemical_compound, Amyloid beta-Protein Precursor, Alzheimer Disease, Cell Line, Tumor, mental disorders, Endopeptidases, Phorbol Esters, Amyloid precursor protein, Aspartic Acid Endopeptidases, Humans, Enzyme Inhibitors, Amyloid beta-Peptides, biology, Secretory Vesicles, P3 peptide, Metalloendopeptidases, General Medicine, Dipeptides, Compartmentalization (psychology), Peptide Fragments, Cell Compartmentation, ADAM Proteins, Protein Transport, Alpha secretase, Biochemistry, chemistry, biology.protein, Phorbol, Amyloid Precursor Protein Secretases, Amyloid precursor protein secretase
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9d71192f9fabc7cd5b93c5b77e31c1eTest
https://pubmed.ncbi.nlm.nih.gov/15314262Test -
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المؤلفون: Kumar Sambamurti, Debomoy K. Lahiri, Rosa M. Canet, John Hardy, Laura Marlow, Sharie J. Haugabook
المصدر: Biochemical and biophysical research communications. 305(3)
مصطلحات موضوعية: Amyloid, Macromolecular Substances, Protein subunit, Biophysics, Nicastrin, CHO Cells, Biology, Biochemistry, Models, Biological, Presenilin, Cell Line, Amyloid beta-Protein Precursor, RNA interference, PEN-2, Alzheimer Disease, Cricetinae, mental disorders, Endopeptidases, Presenilin-1, Animals, Aspartic Acid Endopeptidases, Humans, APH-1, Molecular Biology, Amyloid beta-Peptides, Membrane Glycoproteins, Membrane Proteins, Cell Biology, Peptide Fragments, Enzyme Activation, Protein Subunits, biology.protein, Amyloid Precursor Protein Secretases, Biogenesis, Peptide Hydrolases
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12dd5b02b425ff399593a3e8d136e901Test
https://pubmed.ncbi.nlm.nih.gov/12763021Test -
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المؤلفون: Frederick Esch, Nikolaos K. Robakis, Kumar Sambamurti, Pamela S. Keim, John P. Anderson, Ivan Lieberburg
المصدر: Neuroscience Letters. 128:126-128
مصطلحات موضوعية: Neurons, biology, medicine.diagnostic_test, General Neuroscience, Proteolysis, P3 peptide, Cleavage (embryo), medicine.disease, PC12 Cells, Carboxypeptidase, Amyloid beta-Protein Precursor, chemistry.chemical_compound, chemistry, Biochemistry, Alzheimer Disease, Cell culture, mental disorders, Chromatography, Gel, biology.protein, Amyloid precursor protein, medicine, Animals, Cyanogen bromide, Alzheimer's disease
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4696f12e642b072b81445be79c19fc8aTest
https://doi.org/10.1016/0304-3940Test(91)90775-o -
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المؤلفون: Terrone L. Rosenberry, Thillai Koothan, Linda H. Younkin, Christian Mihail Prada, Debra Yager, Swetal Gandhi, Yasumasa Ohyagi, Lawrence M. Refolo, Steven G. Younkin, Daniel Sevlever, Inga Pinnix, Kumar Sambamurti, Christopher B. Eckman, Luisa Onstead
المصدر: The Journal of biological chemistry. 274(38)
مصطلحات موضوعية: Amyloid, Glycosylphosphatidylinositols, Mutant, Guinea Pigs, CHO Cells, Biochemistry, Phosphoinositide Phospholipase C, Alzheimer Disease, Cricetinae, mental disorders, Endopeptidases, Animals, Aspartic Acid Endopeptidases, Humans, Secretion, Molecular Biology, Cells, Cultured, Protein Kinase C, Amyloid beta-Peptides, biology, Phospholipase C, Chinese hamster ovary cell, Hydrolysis, Phosphatidylinositol Diacylglycerol-Lyase, P3 peptide, Brain, Cell Biology, nervous system diseases, Enzyme Activation, Type C Phospholipases, biology.protein, Amyloid Precursor Protein Secretases, Amyloid precursor protein secretase, Biogenesis
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72b3c1b38ce396e3c60544329495f091Test
https://pubmed.ncbi.nlm.nih.gov/10480887Test