المؤلفون: Rantanen, Laura M., Bitar, Maina, Lampinen, Riikka, Stewart, Romal, Quek, Hazel, Oikari, Lotta E., Cuni-Lopez, Carla, Sutharsan, Ratneswary, Thillaiyampalam, Gayathri, Iqbal, Jamila, Russell, Daniel, Penttila, Elina, Lopponen, Heikki, Lehtola, Juha-Matti, Saari, Toni, Hannonen, Sanna, Koivisto, Anne M., Haupt, Larisa M., Mackay-Sim, Alan, Cristino, Alexandre S., Kanninen, Katja M., White, Anthony R.

المساهمون: Department of Neurosciences, University of Helsinki, HUS Neurocenter, Neurologian yksikkö

مصطلحات موضوعية: Akap6, Alzheimer's disease, RNA Sequencing, Aging, Cognition, Mild cognitive impairment, Olfactory neurosphere-derived cells, Patient-derived olfactory mucosa, 1182 Biochemistry, cell and molecular biology, 3112 Neurosciences, 3124 Neurology and psychiatry

وصف الملف: application/pdf

العلاقة: Rantanen , L M , Bitar , M , Lampinen , R , Stewart , R , Quek , H , Oikari , L E , Cuni-Lopez , C , Sutharsan , R , Thillaiyampalam , G , Iqbal , J , Russell , D , Penttila , E , Lopponen , H , Lehtola , J-M , Saari , T , Hannonen , S , Koivisto , A M , Haupt , L M , Mackay-Sim , A , Cristino , A S , Kanninen , K M & White , A R 2022 , ' An Alzheimer's Disease Patient-Derived Olfactory Stem Cell Model Identifies Gene Expression Changes Associated with Cognition ' , Cells , vol. 11 , no. 20 , 3258 . https://doi.org/10.3390/cells11203258Test; c64e6de2-0264-4cc9-9fbe-b0d185ee69e5; http://hdl.handle.net/10138/572248Test; 000872406800001

الإتاحة: http://hdl.handle.net/10138/572248Test

المؤلفون: Välimäki, Tarja, Koivisto, Anne M., Selander, Tuomas, Saari, Toni, Hallikainen, Ilona

المصدر: Clinical Gerontologist; 2024, Vol. 47 Issue 2, p234-243, 10p

مصطلحات موضوعية: MENTAL depression risk factors, PATIENT aftercare, ALZHEIMER'S disease, NEUROPSYCHOLOGY, RISK assessment, PSYCHOLOGICAL tests, PSYCHOLOGY of caregivers, DESCRIPTIVE statistics, SOCIODEMOGRAPHIC factors, LONGITUDINAL method, PSYCHOLOGICAL distress

المؤلفون: Lampinen, Riikka, Gorova, Veronika, Avesani, Simone, Liddell, Jeffrey R., Penttilä, Elina, Zavodna, Tana, Krejcik, Zdenek, Lehtola, Juha-Matti, Saari, Toni, Kalapudas, Juho, Hannonen, Sanna, Lopponen, Heikki, Topinka, Jan, Koivisto, Anne M., White, Anthony R., Giugno, Rosalba, Kanninen, Katja M.

المساهمون: Department of Neurosciences, University of Helsinki, Neurologian yksikkö, HUS Internal Medicine and Rehabilitation, HUS Neurocenter, Faculty of Medicine, Geriatrian yksikkö

مصطلحات موضوعية: Alzheimer's disease, olfactory mucosa cells, biometals, zinc, calcium, sodium, alpha-2-macroglobulin, olfactory dysfunction, BETA-AMYLOID PEPTIDE, ALPHA(2)-MACROGLOBULIN, DEMENTIA, GENE, MACROGLOBULIN, ASSOCIATION, GUIDELINES, PROTEOME, Biochemistry, cell and molecular biology, Neurosciences

وصف الملف: application/pdf

العلاقة: This research was funded by The Academy of Finland (295425), The Sigrid Juselius Foundation, and the University of Eastern Finland. The APC was funded by University of Eastern Finland basic funding.; Lampinen , R , Gorova , V , Avesani , S , Liddell , J R , Penttilä , E , Zavodna , T , Krejcik , Z , Lehtola , J-M , Saari , T , Kalapudas , J , Hannonen , S , Lopponen , H , Topinka , J , Koivisto , A M , White , A R , Giugno , R & Kanninen , K M 2022 , ' Biometal Dyshomeostasis in Olfactory Mucosa of Alzheimer's Disease Patients ' , International Journal of Molecular Sciences , vol. 23 , no. 8 , 4123 . https://doi.org/10.3390/ijms23084123Test; http://hdl.handle.net/10138/343462Test; 5be5e7be-6de8-4864-b632-e1886ab7db07; 000786332900001

الإتاحة: http://hdl.handle.net/10138/343462Test

المؤلفون: Hannonen, Sanna, Andberg, Sami, Kärkkäinen, Virve, Rusanen, Minna, Lehtola, Juha-Matti, Saari, Toni, Korhonen, Ville, Hokkanen, Laura, Hallikainen, Merja, Hänninen, Tuomo, Leinonen, Ville, Kaarniranta, Kai, Bednarik, Roman, Koivisto, Anne M.

المساهمون: Department of Psychology and Logopedics, University of Helsinki, Department of Neurosciences, HUS Neurocenter, Neurologian yksikkö, Geriatrian yksikkö

مصطلحات موضوعية: Alzheimer's disease, biomarker, CERAD, eye tracking, King-Devick, mild cognitive impairment, saccadic eye movements, CERAD NEUROPSYCHOLOGICAL BATTERY, KING-DEVICK TEST, ASSOCIATION WORKGROUPS, DIAGNOSTIC GUIDELINES, NATIONAL INSTITUTE, RECOMMENDATIONS, DEMENTIA, ALLELE, 3112 Neurosciences, 3124 Neurology and psychiatry, 515 Psychology, Neuropsychology

وصف الملف: application/pdf

العلاقة: We are deeply grateful to all of the study participants. We also thank BEGAD research project study nurses Ulla Vanhanen, Kati Monttinen, and Kristiina Holopainen for recruiting the study participants. We thank biostatistician Tuomas Selander for help with the statistical analysis. This work was supported by Juho and Lempi Pitkanen Foundation.; Hannonen , S , Andberg , S , Kärkkäinen , V , Rusanen , M , Lehtola , J-M , Saari , T , Korhonen , V , Hokkanen , L , Hallikainen , M , Hänninen , T , Leinonen , V , Kaarniranta , K , Bednarik , R & Koivisto , A M 2022 , ' Shortening of Saccades as a Possible Easy-to-Use Biomarker to Detect Risk of Alzheimer's Disease ' , Journal of Alzheimer's Disease , vol. 88 , no. 2 , pp. 609-618 . https://doi.org/10.3233/JAD-215551Test; ORCID: /0000-0001-8342-9248/work/117173311; cf23b6b3-9995-43a9-a640-5ab028bd110c; http://hdl.handle.net/10138/346799Test; 000828034300020

الإتاحة: http://hdl.handle.net/10138/346799Test

المؤلفون: Lampinen, Riikka, Fazaludeen, Mohammad Feroze, Avesani, Simone, Ord, Tiit, Penttila, Elina, Lehtola, Juha-Matti, Saari, Toni, Hannonen, Sanna, Saveleva, Liudmila, Kaartinen, Emma, Fernandez Acosta, Francisco, Cruz-Haces, Marcela, Lopponen, Heikki, Mackay-Sim, Alan, Kaikkonen, Minna U., Koivisto, Anne M., Malm, Tarja, White, Anthony R., Giugno, Rosalba, Chew, Sweelin, Kanninen, Katja M.

المساهمون: Department of Neurosciences, Neurologian yksikkö, HUS Neurocenter, Geriatrian yksikkö

مصطلحات موضوعية: Alzheimer's disease, olfactory mucosa, amyloid beta, single-cell RNA-sequencing, mitochondria, BETA, EXPRESSION, BRAIN, TAU, NEUROGENESIS, DYSFUNCTION, CONSORTIUM, EPITHELIUM, ESTABLISH, REGISTRY, 3112 Neurosciences, 3124 Neurology and psychiatry, 1182 Biochemistry, cell and molecular biology

وصف الملف: application/pdf

العلاقة: This research was funded by The Academy of Finland (295425), The Sigrid Juselius Foundation, The Finnish Cultural Foundation, The Inkeri and Mauri Vanska Foundation, The Yrjo Jahnsson Foundation, The Saastamoinen Foundation and The Finnish Brain Foundation. This project has received funding from the European Union's Horizon 2020 research and innovation programme under grant agreement No 814978.; Lampinen , R , Fazaludeen , M F , Avesani , S , Ord , T , Penttila , E , Lehtola , J-M , Saari , T , Hannonen , S , Saveleva , L , Kaartinen , E , Fernandez Acosta , F , Cruz-Haces , M , Lopponen , H , Mackay-Sim , A , Kaikkonen , M U , Koivisto , A M , Malm , T , White , A R , Giugno , R , Chew , S & Kanninen , K M 2022 , ' Single-Cell RNA-Seq Analysis of Olfactory Mucosal Cells of Alzheimer's Disease Patients ' , Cells , vol. 11 , no. 4 , 676 . https://doi.org/10.3390/cells11040676Test; 9418c0ce-00e1-44de-8e9b-67d358dc255d; http://hdl.handle.net/10138/342420Test; 000763939800001

الإتاحة: http://hdl.handle.net/10138/342420Test

المؤلفون: Rantanen, Laura M., Bitar, Maina, Lampinen, Riikka, Stewart, Romal, Quek, Hazel, Oikari, Lotta E., Cuni-Lopez, Carla, Sutharsan, Ratneswary, Thillaiyampalam, Gayathri, Iqbal, Jamila, Russell, Daniel, Penttila, Elina, Lopponen, Heikki, Lehtola, Juha Matti, Saari, Toni, Hannonen, Sanna, Koivisto, Anne M., Haupt, Larisa M., Mackay-Sim, Alan, Cristino, Alexandre S., Kanninen, Katja M., White, Anthony R.

المصدر: Cells

مصطلحات موضوعية: aging, AKAP6, Alzheimer’s disease, cognition, mild cognitive impairment, olfactory neurosphere-derived cells, patient-derived olfactory mucosa, RNA Sequencing

وصف الملف: application/pdf

العلاقة: https://eprints.qut.edu.au/236508/1/118008542.pdfTest; Rantanen, Laura M., Bitar, Maina, Lampinen, Riikka, Stewart, Romal, Quek, Hazel, Oikari, Lotta E., Cuni-Lopez, Carla, Sutharsan, Ratneswary, Thillaiyampalam, Gayathri, Iqbal, Jamila, Russell, Daniel, Penttila, Elina, Lopponen, Heikki, Lehtola, Juha Matti, Saari, Toni, Hannonen, Sanna, Koivisto, Anne M., Haupt, Larisa M., Mackay-Sim, Alan, Cristino, Alexandre S., Kanninen, Katja M., & White, Anthony R. (2022) An Alzheimer's Disease Patient-Derived Olfactory Stem Cell Model Identifies Gene Expression Changes Associated with Cognition. Cells, 11(20), Article number: 3258.; https://eprints.qut.edu.au/236508Test/; Centre for Genomics and Personalised Health; Faculty of Health; School of Biomedical Sciences

الإتاحة: https://doi.org/10.3390/cells11203258Test
https://eprints.qut.edu.au/236508Test/

المؤلفون: Saari, Toni, Koivisto, Anne, Hintsa, Taina, Hänninen, Tuomo, Hallikainen, Ilona

المساهمون: Department of Neurosciences, University of Helsinki, HUS Internal Medicine and Rehabilitation, Geriatrian yksikkö, Department of Medicine

مصطلحات موضوعية: validity, reliability, SYMPTOMS, BEHAVIORAL-DISORDERS, DEMENTIA, Neuropsychiatric Inventory, PSYCHOPATHOLOGY, 3112 Neurosciences, Alzheimer's disease, CONSTRUCT-VALIDATION, behavioral and psychological symptoms of dementia, humanities, 3124 Neurology and psychiatry, ALZHEIMERS-DISEASE, mental disorders, neuropsychiatric symptoms, measurement, CHINESE VERSION, NPI

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=od______1593::0af3eb122841f9675cec40191207ee88Test
http://hdl.handle.net/10138/343421Test

المؤلفون: Ylä-Herttuala, Salla, Hakulinen, Mikko, Poutiainen, Pekka, Laitinen, Tiina M., Koivisto, Anne M., Remes, Anne M., Hallikainen, Merja, Lehtola, Juha-Matti, Saari, Toni, Korhonen, Ville, Könönen, Mervi, Vanninen, Ritva, Mussalo, Hanna, Laitinen, Tomi, Mervaala, Esa, Castelo-Branco, Miguel

المصدر: Journal of Alzheimer's Disease; 2020, Vol. 79 Issue 1, p153-161, 9p

مصطلحات موضوعية: SLEEP apnea syndromes, CEREBRAL amyloid angiopathy, OLDER patients, ALZHEIMER'S disease, GLUCOSE metabolism, MAGNETIC resonance imaging, SEVERITY of illness index, AMINES, RADIOPHARMACEUTICALS, DEOXY sugars, CEREBRAL cortex, PEPTIDES, THIAZOLES

المؤلفون: Saari, Toni, Hallikainen, Ilona, Hintsa, Taina, Koivisto, Anne M.

المصدر: International Psychogeriatrics; Jun2020, Vol. 32 Issue 6, p741-751, 11p

المؤلفون: Saari, Toni¹, Räty, Hannu¹, Hallikainen, Ilona², Koivisto, Anne^2,3, Hänninen, Tuomo³, Hänninen, Tuomo⁴ (AUTHOR), Räty, Hannu⁵ (AUTHOR)

المصدر: Journal of Alzheimer's Disease. 2018, Vol. 64 Issue 1, p269-279. 11p.

مصطلحات موضوعية: *COGNITION, *ALZHEIMER'S disease, *DEMENTIA, *FOLLOW-up studies (Medicine), *ACTIVITIES of daily living